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All Journal JURNAL GIZI INDONESIA As-syifaa Jurnal Farmasi ANNALES BOGORIENSES Jurnal Keperawatan Muhammadiyah Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Seminar Nasional Lahan Suboptimal Jurnal Ilmiah Keperawatan M A T H L I N E : Jurnal Matematika dan Pendidikan Matematika Babul Ilmi Jurnal Ilmiah Multi Science Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Kesehatan Tambusai Masker Medika Real Coster Journal of Health Science Makara Journal of Technology Jurnal Rakat Sehat : Pengabdian Kepada Masyarakat Jurnal Keperawatan International Journal of Health Sciences Epidemiological Journal of Indonesia Journal of World Future Medicine, Health and Nursing Agritechpedia: Journal of Agriculture and Technology Frontiers in Community Service and Empowerment Al-Suaibah Midwifery Journal
Minarti Minarti
Research Center of Chemistry, Indonesian Institute of Scinces, Kawasan Puspiptek Serpong, Tangerang 15314, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Isolation and Identification of Antiplasmodial Compound from Methanol Extract of Calophyllum bicolor P. F. Steven Abbas, Jamilah; Hanafi, Muhammad; Artanti, Nina; Sundowo, Andini; Minarti, Minarti; Asih, Puji Budi Setia; Syafrudin, Din
ANNALES BOGORIENSES Vol 19, No 2 (2015): Annales Bogorienses
Publisher : Research Center for Biotechnology - Indonesian Institute of Sciences (LIPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/ab.v19i2.253

Abstract

Calophyllum bicolor (Clusiacea) is a big tree from Indonesian rain forest in Palangkaraya, Central Kalimantan. Calophyllum or bintagor is one of many sources of natural bioactive compounds that can be used in the fields of health and pharmaceuticals. The aim of this research was to explore the antiplasmodial activity of methanol extract of Calophyllum bicolor P.F. Steven against Plasmodium falciparum. The methanol extract was purified by colomn chromatography system, hexane – ethyl acetate was used as solvent with increasing polarity. One pure compound was obtained and was elucidated based on the 1H-&13C-NMR and 2D-NMR, [COSY, HMBC and HMQC] data and the isolated compound was identified as xanthone. Methanol extract showed antiplasmodial activity growth inhibition against P. falciparum with IC50 5.2 ppm and the new 5-methoxy trapezifolixanthone compound have maximum inhibition at concentration 0.11 nMol.
Factors Affecting the Development of Anxiety in Postmenopausal Women: A CrossSectional Study in Coastal Areas Saimin, Juminten; Wicaksono, Satrio; Junuda, Junuda; Minarti, Minarti
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.747 KB) | DOI: 10.32771/inajog.v6i3.775

Abstract

  Objective: To analyze factors associated with anxiety in postmenopausal women.   Methods: This study was descriptive analytic with cross-sectional approach conducted in 228 postmenopausal women that aged 50-64 years old in coastal areas of Kendari City. Samples were taken by simple random sampling. The technique of collecting data used questionnaires and the Taylor Manifest Anxiety Scale (T-MAS). Data were analyzed using Chi-square test with a significance value p  0.05.   Results: The results showed that 188 respondents (82.4%) had. anxiety. Its most experienced anxiety was aged 50-54 years old (37.7%), low education (96.0%), as housewife (62.7%), low income (91.2%) and lived with a partner (54.4%). There was correlation between anxiety with age (p=0.016), education level (p = 0.009), income (p = 0.011), and residence status (p = 0.029). There was no correlation between anxiety with occupation (p = 0.351).   Conclusion: There was a correlation between anxiety in postmenopausal women in coastal areas with age, education level, income, and residence status.   Keywords: age, anxiety, education level, income, postmenopausal women, residence status
Factors Affecting the Development of Anxiety in Postmenopausal Women: A CrossSectional Study in Coastal Areas Saimin, Juminten; Wicaksono, Satrio; Junuda, Junuda; Minarti, Minarti
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.747 KB) | DOI: 10.32771/inajog.v6i3.775

Abstract

  Objective: To analyze factors associated with anxiety in postmenopausal women.   Methods: This study was descriptive analytic with cross-sectional approach conducted in 228 postmenopausal women that aged 50-64 years old in coastal areas of Kendari City. Samples were taken by simple random sampling. The technique of collecting data used questionnaires and the Taylor Manifest Anxiety Scale (T-MAS). Data were analyzed using Chi-square test with a significance value p  0.05.   Results: The results showed that 188 respondents (82.4%) had. anxiety. Its most experienced anxiety was aged 50-54 years old (37.7%), low education (96.0%), as housewife (62.7%), low income (91.2%) and lived with a partner (54.4%). There was correlation between anxiety with age (p=0.016), education level (p = 0.009), income (p = 0.011), and residence status (p = 0.029). There was no correlation between anxiety with occupation (p = 0.351).   Conclusion: There was a correlation between anxiety in postmenopausal women in coastal areas with age, education level, income, and residence status.   Keywords: age, anxiety, education level, income, postmenopausal women, residence status
PENGARUH KOMPOSISI HERBAL DALAM MINUMAN TEH HIJAU GAMBUNG HERBAL TERHADAP HAMBATAN α-GLUKOSIDASE Megawati, Megawati; Mulyani, Hani; Minarti, Minarti; Ernawati, Teni; Darmawan, Akhmad
Jurnal Ilmiah As-Syifaa Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (650.017 KB) | DOI: 10.33096/jifa.v10i2.434

Abstract

The aim of this study is to make a formula of green tea that is enriched by other herbs. Green tea drinks are made using the basic ingredients of gambung (THG) green tea enriched with sapodilla leaves (Manilkara zapota (Aw) bay leaves (Syzygium polyanthum (Am), Artocarpus communis (Un) breadfruit leaves, and cinnamon leaves (Cinnamomum verum (K)). The composition of gambung herbal green tea is made by reference to the antidiabetic activity of each herb. All the samples were tested for inhibition of α-glucosidase enzymes and toxicity using the lethality test method for brine shrimp. All samples showed good inhibition of the α-glucosidase enzyme barriers of gamboeng green tea (THG) 82.05%, sapodilla leaves (Aw) 97.81%, breadfruit leaves (Un) 73.34%, bay leaves (Am) 93.80%, cinnamon leaves (K) 91.24 %. The inhibition value of α-glucoside enzymes in the formulation of gamboeng herbal green tea drinks: 96.203% (GKUn) is higher when compared to the GKAm formula (94.78%) and GKAw (62.487%).
BERAT BADAN BAYI BARU LAHIR,POSISI IBU MELAHIRKAN, DENGAN KEJADIAN ROBEKAN PERENIUM PADA IBU BERSALIN NORMAL Minarti, Minarti
Masker Medika Vol 6 No 2 (2018): Masker Medika
Publisher : IKesT Muhammadiyah Palembang

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Abstract

Latar belakang: Robekan perineum adalah perlukaan jalan lahir yang terjadi pada saat kelahiran bayi baik menggunakan alat maupun tidak manggunakan alat (Ilmiah, 2015). Penelitian ini bertujuan: untuk mengetahui Hubungan Berat Badan Bayi Baru Lahir dan Posisi Ibu Melahirkan Terhadap Kejadian Robekan Perineum Pada Ibu Bersalin Normal di Puskesmas Talang Jaya Raya kec. betung kab. banyuasinTahun 2017. Metode Penelitian: ini menggunakan metode survey analitik kuantitatif dengan pendekatan cross sectional dimana data variabel dependen robekan perenium dan variable independent Berat Badan Bayi Lahir dan posisi ibu melahirkan.Populasi dalam penelitian ini adalah Seluruh ibu yang melahirkan yang tercatat direkam medik Puskesmas Talang jaya raya kec. betung kab. Banyuasintahun 2017, yaitu sebanyak 1328. Pengambilan sample dengan mengunakan teknik total sampling, jadi besar populasi 93 responden. Hasil penelitian: menunjukkan ada hubungan yang bermakna antara berat badan bayi baru lahir dan posisi ibu melahirkan terhadap kejadian robekan perinium secara statistik. Disarankan pada petugas puskesmas talang jaya raya kec. betung kab.banyuasin Agar menurunkan kejdian Robekan Perineum. Background Perineal rupture is a birth canal injury that occurs at the time of birth of the baby either using the tool or not manggunakan tool (Ilmiah, 2015). This research aims to determine the relationship of Newborn Weight Loss and Maternal Position of Against Perineum Rupture in Normal Maternity Mothers at health center of talang jaya raya kec. betung kab.banyuasin Year 2017.Methods Research methods uses a quantitative analytical survey method with cross sectional approach where the dependent variable data (BBBL). The population in this study were all mothers who gave birth recorded recorded medical health center of talang jaya raya kec. betung kab.banyuasin 2017, that is as much as 1328. Sampling by using total sampling technique, so large population of 93 respondents. It is recommended which showed there was significant relationship between new baby weight Birth and the position of the mother gave birth to the incidence of perinium rupture statistically. Suggested to the officers of Islamic hospital siti khadijah palembang. In order to decrease the peregrity of perinium rupture
In vitro lipase enzyme inhibitory activities of green tea and other herbs Megawati, Megawati; Artanti, Nina; Mulyani, Hani; Darmawan, Akhmad; Syahrian, Heri; Lotulung, Puspa Dewi N.; Supriadi, Edi; Widiyarti, Galuh; Dewi, Rizna Triana; Meilawati, Lia; Ernawati, Teni; Dewijanti, Indah Dwiatmi; Minarti, Minarti
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 9, No 1 (2020)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.9.1.48-52

Abstract

Background: Increased lipase activity can increase the amount of monoglycerides and fatty acids absorbed by the body, this is what affects obesity. If pancreatic lipase activity is inhibited, the production of fatty acids will decrease, consequently the level of fat in the blood will also decrease.Objective: To study anti obesity potential of a single herb or a mixture of green tea and other herbs (Syzygium polyanthum. Lv, Artocarpus communis.Lv, Cinnamomum verum..Lv, Manilkara zapota.Lv, Tectona grandis.Lv) by the in vitro inhibition assay of the lipase enzyme activityMethod: A single (8 herbs) or a mixture of three herbs powder (12 formulas) was put into a tea bag with a total weight of 1.5 g to be brewed in 100 mL bottled mineral water at 70⁰-90⁰C for 10 minutes. In vitro lipase enzyme inhibition assay were conducted to measure the ability of these samples as lipase inhibitor. Orlistat used as positive lipase inhibitor. Results: There was a difference results of lipase inhibition activity between the sample of a single and a mixture of herbs. Interestingly, the results shows that formula 3 (mixture of green tea, Manilkara zapota and cinnamon). has 53.942 % inhibition, formula 9 (a mixture of green tea, Syzygium polyanthum and cinnamon) has 67.322 % inhibition and formula 12 (a mixture of green tea, Tectona grandis and cinnamon) has 56.612 % inhibition which close to lipase inhibitory activity by standard Orlistat.Conclusion: The mixture of green tea and two other herbs has a lipase inhibitory activity similar to Orlistat, when compared to the single herb. The highest lipase inhibitory activity is found in formula 9.
Production of Lovastatin and Sulochrin by Aspergillus Terreus Using Solid State Fermentation Dewi, Rizna Triana; Artanti, Nina; Mulyani, Hani; Lotulung, Puspa Dewi Narrij; Minarti, Minarti
Makara Journal of Technology Vol. 15, No. 1
Publisher : UI Scholars Hub

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Abstract

Lovastatin is an anti-cholesterol agent that was produced by Aspergillus terreus using solid state fermentation (SSF). During this fermentation process, sulochrin is also produced as an unwanted co-metabolite. However, our previous result showed that sulochrin had potential as antidiabetes because it is an inhibitor agent of α-glucosidase. In this paper, we reported our observation on lovastatin and sulochrin production pattern in relation with inhibitor α-glucosidase activity during eleven days fermentation of A. terreus koji (SSF) ethyl acetate extract. Koji obtained from solid state fermentation with rice as the substrate and incubated at room temperature, sample is taken daily for eleven day (D-1 to D-11). Lovastatin and sulochrin production was measured by Liquid Chromatography- Mass Spectrometer based on their molecular weight m/z 404.5 and 332.3 respectively. The inibitory activity is measured by inhibition model of koji extract against α-glucosidase (EC 3.2.1.20) from Saccharomyces cereviceae. The results show that lovastatin production was started on the day 2 (0.04 mg/g) and achieving the optimal production on day 7 (11.46 mg/g), while sulochrin production was started on day 4 (0.60 mg/g) and keep produced until the end of fermentation period at Day 11 (3.11 mg/g). Koji extract was started to show inhibitory to α-glucosidase activity on Day 5 (IC50= 23.34 μg/mL) and keep showed activity until Day 11 (IC50=3.33 μg/mL). These results suggest that inhibitory activity of koji extract to α- glucosidase activity have relation with sulochrin biosynthesis production.
HUBUNGAN PERAN TENAGA DAN MOTIVASI TERHADAP KELENGKAPAN IMUNISASI TETANUS TOKSOID PADA IBU HAMIL Minarti, Minarti; Chandra, Tiara Ayu; Riani, Lita
JOURNAL OF HEALTH SCIENCE Vol 1 No 2 (2023): Journal of Health Science
Publisher : LPPM Universitas Kader Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (507.184 KB)

Abstract

Tetanus Toxoid (TT) immunization is a process to build immunity as an effort to prevent tetanus infection (Indanati, 2015). The tetanus vaccine is a toxin from the tetanus germ that has been weakened and then purified. The immunity that is transmitted from mother to baby can be a protection for babies against stressors (unsterile delivery and unclean umbilical cord care) that can cause TN. This research is a quantitative research with an analytical survey with a cross sectional approach. The population in this study were all pregnant women who visited totaling 36 pregnant women. The sample of this research used systematic random sampling method. The sample of this study amounted to 36 respondents. Data analysis was carried out in two stages, namely univariate analysis and bivariate analysis with Chi-square statistical test. The results of the bivariate analysis showed that there was a relationship between the role of health workers (p value = 0.022) and there was a relationship between motivation (p value = 0.040) and the completeness of tetanus toxoid (TT) immunization for pregnant women. The advice given is expected to be a source of information, input and improve the quality of services, especially regarding TT immunization for pregnant women. Keywords: Completeness of Tetanus Toxoid Immunization for Pregnant Women
HUBUNGAN JUMLAH ANAK, DUKUNGAN SUAMI, DAN PENGETAHUAN DALAM PEMILIHAN KONTRASEPSI IUD (INTRA UTERINE DEVICE) Purwanti, Kristin; Nati Indriani, Putu Lusita; Minarti, Minarti
Babul Ilmi Jurnal Ilmiah Multi Science Kesehatan Vol 15, No 2 (2023): Babul Ilmi Jurnal Ilmiah Multi Science Kesehatan
Publisher : STIKES 'Aisyiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36729/bi.v15i2.1140

Abstract

Latar Belakang: Cakupan peserta KB baru dan aktif  Intra Uterine Device (IUD) di Indonesia pada tahun 2021 sebanyak 8,0%, Faktor-faktor yang mempengaruhi kurangnya pemilihan kontrasepsi IUD antara lain; pengetahuan, jumlah anak, dan  dukungan suami, kurangnya pemahaman masyarakat tentang IUD serta kurangnya kesadaran masyarakat untuk menggunakannya.Tujuan: untuk mengetahui Hubungan Jumlah anak, Dukungan Suami dan Pengetahuan dalam Pemilihan Kontrasepsi IUD. Metode:  Penelitian ini bersifat kuantitatif secara Survey Analitik dengan pendekatan cross Sectional. Populasi penelitian ini adalah semua peserta KB yang menggunakan IUD dan yang tidak menggunakan IUD pada  bulan  Juni tahun 2023 di PMB Hj. Sri Nirmala, S.ST., Bd. sebanyak 80 peserta. Pengambilan sampel secara accidental sampling. Analisis bivariat dengan menggunakan uji chi-square Hasil: di dapatkan tidak ada hubungan antara jumlah anak dengan pemilihan kontrasepsi IUD  dimana p value 0,296 > 0,05 OR 0,206. Ada hubungan antara dukungan suami dengan pemilihan kontrasepsi IUD  dimana p value 0,000 < 0,05 OR 5,000. Ada hubungan antara pengetahuan dengan pemilihan kontrasepsi IUD dimana p value 0,000 < 0,05 OR 5,000. Saran: Dengan Meningkatkan KIE (Konseling, Informasi, dan Edukasi)  pada Pasangan Usia Subur (PUS) sehingga jumlah PUS banyak memilih Kontrasepsi IUD di banding dengan KB  lainnya. Kata kunci : IUD, Jumlah anak, dukungan suami, pengetahuan.
Kepatuhan Minum Obat Pada Klien Hipertensi Di Wilayah Kerja Puskesmas Wonokusumo Surabaya Febiayuni, Nabila; Ongko Waluyo, Kiaonarni; padoli, Padoli; Minarti, Minarti
JURNAL KEPERAWATAN Vol. 17 No. 1 (2023)
Publisher : JURUSAN KEPERAWATAN POLITEKNIK KESEHATAN KEMENKES SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/nersbaya.v17i1.35

Abstract

ABSTRAK Hipertensi atau tekanan darah tinggi adalah peningkatan tekanan darah sistolik lebih dari 140 mmHg dan tekanan darah diastolik lebih dari 90 mmHg. Klien hipertensi harus memahami dan menumbuhkan kesadaran diri terhadap penyakitnya, dan melakukan perawatan mandiri seperti salah satunya patuh minum obat antihipertensi. Semakin patuh klien saat mengkonsumsi obat maka tekanan darah akan terkontrol dengan baik. Tujuan dari penelitian ini adalah mengetahui tingkat kepatuhan minum obat pada klien hipertensi di wilayah kerja Puskesmas Wonokusumo Surabaya. Jenis penelitian yang digunakan adalah penelitian deskriptif dengan pendekatan cross sectional dan menggunakan teknik accidental sampling. Populasi pada penelitian ini adalah seluruh klien hipertensi yang melakukan pemeriksaan di Puskesmas Wonokusumo Surabaya dengan jumlah sampel 85 klien. Pengumpulan data dengan menggunakan kuesioner dari Morisky Medication Adherence Scale (MMAS). Data yang diperoleh kemudian di analisis dikode, dan ditabulasi dan disajikan dalam bentuk tabel. Hasil penelitian menunjukkan bahwa sebagian besar 50,6% memiliki tekanan darah kategori tahap 1 dan sebagian kecil 14,1% memiliki tekanan darah kategori tahap 2, pada tingkat kepatuhan minum obat sebagian besar 57,6% klien hipertensi tidak patuh dan hampir setengahnya 42,4% klien patuh minum obat hipertensi. Klien dan keluarga diharapkan dapat mendukung untuk selalu melakukan pengontrolan tekanan darah dengan rutin serta patuh dalam melakukan pengobatan hipertensi. Kata Kunci : Kepatuhan, Tekanan Darah, Hipertensi ABSTRACT Hypertension or high blood pressure is an increase in systolic blood pressure over 140 mmHg and diastolic blood pressure over 90 mmHg. Hypertension clients should understand and cultivate self-awareness of the disease, and perform self-care such as one of them obediently taking antihypertension drugs. The more obedient the client when taking the drug then the blood pressure will be well controlled. Theadvice of this study is to find out tingkat compliance taking drugs in hypertension clients at work area of Wonokusumo Public Health Center Surabaya. The type of research used is descriptive research with a cross sectional approach and using accidental sampling techniques. The population in this study was all hypertension clients who conducted examinations at Wonokusumo Health Center Surabaya with a sample number of 85 clients. Data collection using questionnaires from the Morisky Medication Adherence Scale (MMAS). The result showed that most of the 50.6% had stage 1 category blood pressure and a small percentage of 14.1% had stage 2 category blood pressure, at the level of adherence to taking medications most of the 57.6% of hypertensive clients were non-compliant and almost half of 42.4% of clients were obedient to take hypertension medications. Families is hoped that can support clients to always control blood pressure regularly and be obedient in treating hypertension. Keywords : Compliance, Blood Pressure, Hypertension
Co-Authors A.A. Ketut Agung Cahyawan W Adinata, Ach. Arfan Agus Mukholid, Agus Akhmad Darmawan Alfatik, Fatma Andini Sundowo Anisa Pertiwi Arfiah Aryadi, Anggi Ayuanda, Leila Nisya Bayu Argaheni, Niken Chandra, Tiara Ayu darwis darwis, darwis Dewijanti, Indah Dwiatmi Dina Raidanti Dintya Ivantarina Elvi Sunarsih Endarini, Lully Hanni Ernita, Lisa Evy Diah Woelansari Febiayuni, Nabila FIKA MINATA WATHAN Galuh Widiyarti Gernauli Purba, Imelda Hani Mulyani, Hani Heri Syahrian, Heri Heru Sulistijono Inoy Trisnaini Insyur, Bergita Irzanita, Irzanita Istanto, Wisnu Jamilah Abbas Juliana Christyaningsih Juminten Saimin, Juminten Junuda, Junuda Junuda, Junuda Kastubi Kastubi, Kastubi Khrisna Agung Cendekiawan, Khrisna Agung Ladyka Viola Aulia Armawan Lara, Lara Leni Novianti Lia Meilawati Lotulung, Puspa Dewi N. Luthfi Rusyadi Luthfiyah, Sari Mahendika, Devin Maksuk Mamik Mamik Martoni Megawati - Minata, Fika Museyaroh, Museyaroh Mutiarawati, Diah Titik Namriah, Namriah Ngguna, Ani Mura Nina Artanti Ningsih, Dewi Andariya Ningsih, Eka Sarofah Nur Anugrahini, Hepta Nurhayani, Delvi NURUL ANNISA Ongko Waluyo, Kiaonarni Padoli Padoli, Padoli Peluw, Zulfikar Pestariati, Pestariati Puji Budi Setia Asih, Puji Budi Purwanti, Kristin Puspa Dewi Narrij Lotulung Puspa Lotulung, Puspa PUTU LUSITA NATI INDRIANI Rahagia, Rasi Rahma Sari, Indah Rajokiaman Sinaga Rembon, Fransiscus S Resman, Resman Riani, Lita Ririn Noviyanti Putri Rizna Dewi Rizna Triana Dewi Ruben, Sethiana Dewi Runtu, Andro Ruben SAHTA GINTING, SAHTA Sari, Erma Puspita Sartika, Diana Sasongkowati, Retno Satrio Wicaksono Setyorini, Dhiana Suhariyadi Suhariyadi Suliati Suliati Supriadi, Edi Supriatin Supriatin, Supriatin Suyono Suyono Syafrudin, Din Tandiola, Rosdiana Teni Ernawati Wahidin, Wahidin Warni, Rosma Wiraningsih, Eti Dwi Yeninar, Fendi Abraham yuliani, meda Yuliastuti, Rizka Yuniarti, Nini Iswara