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IDENTIFIKASI ISOLAT KULIT BATANG WARU (Hibiscus tiliaceus L.) MENGGUNAKAN SPEKTROSKOPI INFRAMERAH Taupik, M.Sc, Muhammad; Adam Mustapa, Muhammad
Journal Syifa Sciences and Clinical Research Vol 1, No 1 (2019): March
Publisher : State University of Gorontalo

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Abstract

Waru (Hibiscustiliaceus L.) bark is a plant that is believed and used by community as a traditional medicine in treatment, especiallytotreat fever. This study aims to analyze the level of a secondary metabolite compound in the bark of waru (Hibiscustiliaceus L.) plant calculated using UV-Vis spectrophotometry and infrared methods. The method used to identify the flavonoid content is Thin Layer Chromatography (TLC) using eluent n-hexane and ethyl acetate at the best comparison (7:3). The result obtained from this study is waru bark extract containing flavonoid compound which is shown from the Rf value of the waru bark methanol extract of 0.82, which the value is close to the Rf value of quarcetine 0.83. Analysis of the flavonoid content of waru bark methanol extract has carried out on The Spectrophotometric UV-Vis at a wavelength of 382 nm and the total flavonoid content obtained is of 10 mg of waru bark methanol extract containing135.2166µg/mL flavonoid compound with percentage of 13.521% and on the Spetroscopy Infrared, based on the obtained peak shows the existence of functional groups of OH, CH aliphatic, C=C aromatic and C-O indicates that this isolat is a flavonoid compound.
ANALISIS KADAR FLAVANOID TOTAL MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS DALAM KULIT BUAH SALAK (Salacca zalacca V.) Adam Mustapa,M.Sc, Mohammad; Taupik, Muhammad; Ramadhan L, Aditya
Journal Syifa Sciences and Clinical Research Vol 1, No 1 (2019): March
Publisher : State University of Gorontalo

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Abstract

The Snake Fruit (Salacca zalacca (Gaertn.) Voss) skin is considered as a waste, but there are a small number of people who use this fruit skin as an medicine. A compound that plays a role in snake fruit skin for the treatment is flavonoid. The purpose of this study was to determine the level of flavonoid contained in the extract of snake fruit skin. The method used to determine the amount of flavonoid compound contained in it is the UV-Vis Spectrophotometry method. The result of reading the absorbance value of each snake fruit fraction obtained from the methanol fraction was 0.568 and ethyl acetate fraction of 0.319, which were then calculated by using the quercetin linear equation standard, y = 0.0608 x -0.0188 with the correlation coefficient (R2) = 0.997. The result obtained for each snake fruit fraction for flavonoid level in the methanol fraction was 96.51 µg/mL and in ethyl acetate fraction was 55.56 µg/mL.
ANALISIS KADAR FLAVANOID TOTAL MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS DALAM KULIT BUAH SALAK (Salacca zalacca V.) Adam Mustapa,M.Sc, Mohammad; Taupik, Muhammad; Ramadhan L, Aditya
Journal Syifa Sciences and Clinical Research Vol 1, No 1 (2019): March
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (547.013 KB)

Abstract

The Snake Fruit (Salacca zalacca (Gaertn.) Voss) skin is considered as a waste, but there are a small number of people who use this fruit skin as an medicine. A compound that plays a role in snake fruit skin for the treatment is flavonoid. The purpose of this study was to determine the level of flavonoid contained in the extract of snake fruit skin. The method used to determine the amount of flavonoid compound contained in it is the UV-Vis Spectrophotometry method. The result of reading the absorbance value of each snake fruit fraction obtained from the methanol fraction was 0.568 and ethyl acetate fraction of 0.319, which were then calculated by using the quercetin linear equation standard, y = 0.0608 x -0.0188 with the correlation coefficient (R2) = 0.997. The result obtained for each snake fruit fraction for flavonoid level in the methanol fraction was 96.51 g/mL and in ethyl acetate fraction was 55.56 g/mL.
IDENTIFIKASI ISOLAT KULIT BATANG WARU (Hibiscus tiliaceus L.) MENGGUNAKAN SPEKTROSKOPI INFRAMERAH Taupik, M.Sc, Muhammad; Adam Mustapa, Muhammad
Journal Syifa Sciences and Clinical Research Vol 1, No 1 (2019): March
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (663.495 KB)

Abstract

Waru (Hibiscustiliaceus L.) bark is a plant that is believed and used by community as a traditional medicine in treatment, especiallytotreat fever. This study aims to analyze the level of a secondary metabolite compound in the bark of waru (Hibiscustiliaceus L.) plant calculated using UV-Vis spectrophotometry and infrared methods. The method used to identify the flavonoid content is Thin Layer Chromatography (TLC) using eluent n-hexane and ethyl acetate at the best comparison (7:3). The result obtained from this study is waru bark extract containing flavonoid compound which is shown from the Rf value of the waru bark methanol extract of 0.82, which the value is close to the Rf value of quarcetine 0.83. Analysis of the flavonoid content of waru bark methanol extract has carried out on The Spectrophotometric UV-Vis at a wavelength of 382 nm and the total flavonoid content obtained is of 10 mg of waru bark methanol extract containing135.2166g/mL flavonoid compound with percentage of 13.521% and on the Spetroscopy Infrared, based on the obtained peak shows the existence of functional groups of OH, CH aliphatic, C=C aromatic and C-O indicates that this isolat is a flavonoid compound.
WASTE PROCESSING TRAINING AS AN ALTERNATIVE MATERIAL FOR CANDLES Suryani, Nuri; Krisdianti, Nana; Pradana, Riski; Taupik, Muhammad; Subiyantoro, Singgih
ADI WIDYA : JURNAL PENGABDIAN MASYARAKAT Vol 4, No 2 (2020): ADIWIDYA
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33061/awpm.v4i2.4403

Abstract

In their life, the people of Siwal Village cannot be separated from the use of oil. Moreover, the majority of Siwal Village residents work as food or fried food sellers on the roadside. Repeated use of cooking oil can have harmful effects on health. In addition, used cooking oil that can no longer be used is usually dumped in careless places and causes environmental pollution. Another problem in Siwal Village is the lack of skills of children due to the influence of gadgets. With these things in mind, training on how to process used cooking oil into an alternative material for making used used wax is one of the right solutions. Activities consist of a location survey, implementation, results and discussion. Implementation includes; 1) preparation 2) counseling 3) training 4) mentoring 5) evaluation 6) advanced stage training. All activities carried out online are able to improve children's skills and reduce environmental pollution due to used waste. Keywords: oil, used cooking, wax
Pemberdayaan Dan Pemanfaatan Tanaman Toga untuk Produk Minuman Immunostimulan di Masa Pandemi Covid 19 Tuloli, Teti S; Taupik, Muhammad
Jurnal Sibermas (Sinergi Pemberdayaan Masyarakat) Vol 9, No 2 (2020): Jurnal Sbermas (Sinergi Bersama Masyarakat)
Publisher : Univeristas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/sibermas.v9i2.7984

Abstract

Kondisi di lapangan menunjukkan bahwa selama ini pemanfaatan dan pengelolaan sumberdaya perdesaan sebagian besar dilakukan oleh laki-laki, mulai dari kegiatan di bidang pertanian, peternakan, industri kecil dan menengah, koperasi, dan kegiatan lain yang sifatnya kegiatan ekonomi. Padahal perempuan sebagai anggota masyarakat juga mempunyai hak untuk ikut serta dalam pemanfaatan dan pengelolaan sumberdaya perdesaan, meskipun kemungkinan peran perempuan tidak sebesar peran laki-laki. Oleh karena itu diperlukan adanya berbagai program yang dapat dilakukan perempuan dalam rangka peningkatan kesejahteraan keluarga dengan memanfaatkan dan mengelola lingkungan sekitarnya. Salah satu program yang dapat dilaksanakan oleh perempuan dalam upaya peningkatan kesejahteraan industri rumah tangga, khususnya di bidang pangan adalah program penanaman dan pemanfaatan Tanaman Obat Keluarga (TOGA).Tujuan dari pengabdian ini adalah meningkatkan pendapatan masyarakat  dimasa pandemi covid 19 sekaligus menyediakan obat yang lebih murah dan efek samping yang lebih ringan. Metode yang digunakan adalah ceramah dan praktik atau demonstrasi. Sehingga masyarakat dapat mempraktikkan secara langsung dan menerapkan dalam  rumah tangga. Dalam pelaksanaannya disampaikan metode pengolahan tanaman TOGA sehingga menjadi minuman immunostimulan yang menyehatkan maupun bagaimana cara menanamnya. Disamping itu juga bagaimana cara mengelola keuangan hasil penjualan hasil pengelohan tanaman TOGA tersebut. Bagaimana strategi pemasarannya kepada masyarakat atau konsumen yang membutuhkan sehingga bisa menghasilkan keuntungan.
Kajian Fitokimia dan Identifikasi Senyawa Metaboli Sekunder Daun Pare (Momordica Charantia L.) Muhammad Taupik; Endah Nurrohwinta Djuwarno; Moh Adam Mustapa
Al-Kimia Vol 9 No 2 (2021): DESEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v9i2.23633

Abstract

Pare plant is a plant that is found in almost every region in the country Indonesia. Plant is used as a traditional medicine to eliminate some diseases. The aim of this study was to isolate and identify the compounds terpenoids methanol extract fraction of n-hexane pare leaf (Momordica charantia L.) using UV-VIS spectrophotometry. Insulation done by maceration method using methanol to produce condensed methanol extract as much as 36.25 grams. Extracts condensed methanol produced is tested phytochemical. Phytochemical test results shows that it contains alkaloids, saponins and steroid / terpenoids. Condensed methanol extract then fractionated using liquid-liquid partition with solvent n-hexane and methanol with a ratio of 4: 2 ie 133 ml of n-hexane and 67 mL of methanol. Non-polar phase (phase n-hexane) results of further partitioning is evaporated using a rotary evaporator to produce a thick n-hexane extract as much as 1.25 grams hereinafter in the TLC test ratio of solvent to produce the best. Solvents are chosen that n-hexane: ethyl acetate (3: 1). Separation and purification was performed using Vacuum Liquid Chromatography (KCV) using silica gel GF254 as stationary phase and solvent n-hexane: methanol as mobile phase and eluted gradually. Isolates were then tested using Thin Layer Chromatography (TLC). Isolates were identified using UV-VIS spectrophotometry. Analysis of physicochemical data qualitatively using UV-VIS spectrophotometry on samples of the methanol extract of N-Hexane fraction pare leaf (Momordica charantia L.) class of compounds containing triterpenoids. This is because the absorption band at a wavelength of 274.2 nm and 432.8 nm with absorbance respectively 0.601 and 0.177 were suspected because of the transition of an electron from n à π*.
The Type Fragmentation Patterns Confirmed Acetaminophen By Using Liquid Chromatography-Mass Spectroscopy (LCMS) From Herbal Medicine (Jamu) Muhammad Taupik; Endah Nurrohwinta Djuwarno; Moh Adam Mustapa; Wiwin R Kunusa; Jafar La Kilo; Muhamad Handoyo Sahumena
Elkawnie: Journal of Islamic Science and Technology Vol 7, No 2 (2021)
Publisher : Universitas Islam Negeri Ar-Raniry Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/ekw.v7i2.7492

Abstract

Abstract: The Jamu or herbal medicine were adulterated with chemical drugs in the last twenty years. One of the chemical drugs that are commonly added to herbal medicine is acetaminophen. Acetaminophen is generally considered an analgesic-antipyretic drug. The research aims to identify the content of paracetamol and its amount added to the jamu. This study consisted of 6 jamu or herbal medicine samples with different brands. The TLC method conducted the qualitative analysis using the mobile phase n-hexane: ethyl acetate (1:1). Three positive samples containing acetaminophen were obtained: D, E, and F. The three positive samples containing acetaminophen were calculated using the LCMS method. Quantitative analysis was conducted with LCMS using a reversed-phase with a mobile phase of acetonitrile: water (15%>: 85%> v/v) at a flow rate of 0.2 mL/min and an injection volume of 5 µL, it was obtained the levels of acetaminophen in sample D as much as  0.16 g/2 g of sample, in sample E of 0.63 g/7 g of sample, and sample F of 0.56 g/7 g of sample. Although the acetaminophen content in herbal medicine is relatively small, according to the Regulation of the Minister of Health of Indonesia No. 007 of 2012, traditional medicine or herbal medicine should not contain synthetic chemicals.Abstrak: Dalam dua puluh tahun terakhir, banyak jamu yang dipalsukan dengan obat-obatan kimia. Salah satu obat kimia yang biasa ditambahkan pada jamu adalah asetaminofen. Acetaminophen umumnya dianggap sebagai obat analgesik-antipiretik. Penelitian ini bertujuan untuk mengetahui kandungan parasetamol dan jumlah yang ditambahkan pada jamu. Sampel penelitian ini terdiri dari 6 sampel jamu dengan merek yang berbeda. Analisis kualitatif dilakukan dengan metode KLT menggunakan fase gerak n-heksana: etil asetat (1:1). Diperoleh tiga sampel positif mengandung asetaminofen, yaitu sampel D, E, dan F. Tiga sampel positif mengandung asetaminofen dihitung menggunakan metode LCMS. Analisis kuantitatif dilakukan dengan LCMS menggunakan fase terbalik dengan fase gerak asetonitril: air (15%>:85%> v/v) pada laju alir 0,2 mL/menit dan volume injeksi 5 µL. Diperoleh kadar asetaminofen pada sampel D sebanyak 0,16 g/2 g sampel, pada sampel E sebesar 0,63 g/7 g sampel, dan pada sampel F sebesar 0,56 g/7 g sampel. Meskipun kandungan asetaminofen dalam jamu relatif sedikit, namun menurut Peraturan Menteri Kesehatan RI No. 007 Tahun 2012, obat tradisional atau jamu tidak boleh mengandung bahan kimia sintetik.
EDUKASI PENGGUNAAN OBAT YANG BENAR MELALUI MEDIA BROSUR BAGI MASYARAKAT Nur Rasdianah; Endah Nurrohwinta Djuwarno; Muhammad Taupik
JMM (Jurnal Masyarakat Mandiri) Vol 6, No 1 (2022): Februari
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (371.914 KB) | DOI: 10.31764/jmm.v6i1.6380

Abstract

Abstrak: Masyarakat memerlukan obat dengan tujuan untuk menyembuhkan atau mencegah timbulnya penyakit. Penggunaan obat secara mandiri lazim ditemui dikalangan masyarakat dengan berbagai alasan dan pertimbagan. Agar masyarakat dapat menggunakan obat dengan aman dan berkhasiat, maka penggunaan obat harus tepat. Penggunaan obat yang benar meliputi cara mendapatkan, menggunakan, menyimpan dan membuang obat. Melalui kegiatan program Pengabdian Masyarakat KKNT UNG 2021 yang berlokasi di Desa Bondat Kecamatan Pagimanana dilakukan kegiatan sosialisasi berupa penyuluhan disertai dengan pembagian brosur berisi materi penggunaan obat yang benar. Sebelum dan sesudah sosialisasi, dilakukan pretest dan posttest, dengan tujuan untuk mengukur tingkat pengetahuan masyarakat mengenai cara penggunaan obat yang tepat. Kategori tingkat pengetahuan terdiri dari: baik, sedang dan buruk,. Dari 67 penduduk desa Bondat yang ikut berpartisipasi dalam kegiatan ini, diketahui warga yang memiliki tingkat pengetahuan dengan kategori baik dari 3 orang ( 4% ) meningkat menjadi 51 orang ( 76%) dan kategori pengetahuan kurang menurun dari 55 orang 82% menjadi 4 orang (6%) setelah mengikuti sosialisasi.Abstract: People need medicine intending to cure or prevent disease. The use of drugs independently is common among the public for various reasons and considerations. So that people can use drugs safely and efficiently, the use of drugs must be appropriate. Correct use of drugs includes how to get, use, store and dispose of drugs. Through the Community Service Program KKNT UNG 2021, located in Bondat Village, Pagimanana District, socialization in the form of counseling is accompanied by brochures containing the correct use of drugs. Before and before socialization, pretest and posttest were conducted to measure the level of public knowledge about the proper use of drugs. The categories of knowledge consist of: good, moderate and bad; of the 67 residents of Bondat village who participated in this activity, it is known that residents who have a good level of knowledge from 3 people (4%) increased to 51 people (76%), and the category of knowledge less decreased from 55 people 82% four people (6%) after participating in the socialization.
PENGARUH KONSENTRASI HYDROXYPROPYL METHYLCELLULOSE SEBAGAI BAHAN PENGIKAT PADA SEDIAAN TABLET EKSTRAK RIMPANG JAHE MERAH (zingiber officinale Var. Rubrum.) Nur AIn Thomas; Widy Susanti Abdulkadir; Muhammad Taupik; Nur Oktaviana
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11667

Abstract

Lozenges are solid preparations made from aromatic and sweet taste that can dissolve slowly in the mouth, which are intended to treat infections in the mouth and throat. Hydroxypropyl Methylcellulose (HPMC) is a binder that can be used in lozenges.This study attempted to examine the effect of the concentration of HPMC as a binder in the tablet preparation of red ginger rhizome extract (Zingiber officinale Var Rubrum) by wet granulation method. This study was a laboratory experimental study by comparing the three concentrations of HPMC binder used in each formula i.e., FI (4%), FII (5%), FIII (6%).The resulting tablets were tested for physical properties including organoleptic tests, weight uniformity, tablet hardness, tablet friability and hedonic tests. Based on the results of the study, it was shown that with an increase in the concentration of the HPMC binder, the physical quality of the resulting tablet also increased. The higher the concentration of HPMC used, the better the uniformity of weight and the high level of tablet hardness. However, tablet friability will decrease. The results showed that the concentrations of 4%, 5%, and 6% had an effect on the tablet physical properties whichwas fragility. Further, formula II with a concentration of 5% had better tablet physical quality and was preferred by respondentsbased on hedonic tests.
Co-Authors A Admiral A. Mu'thi Andy Suryadi A. Muthi Andi Suryadi A. Mu’thi Andy Suryadi A. Mu’thi Andy Suryadi A. Mu’thi Andy Suryadi Abdi Dzul Ikram Hasanuddin Adam Mustapa, Moh Adam Mustapa, Muhammad Adinda, Fadhel Arjuna Ahmad Farhani aldafarista kopman AM. Andy Suryadi Amin, Muhammad Nur Andi Suryadi, A. Mu’thi Andy Suryadi, A. Mu'thi Andy Suryadi, A. Mu’thi Antuli, Zikran Nazar Antuli Aprianto Paneo, Mohamad Ariani H. Hutuba Ariani H. Hutuba Banne, Pratiwi Zesika Beby Bestari Djuarno, Endah Nurrohwintah Dr. Apt. Hamsidar Hasan S.Si.,M.Si Endah Nurrohwinta Djuwarno Faramita Hiola Febriana, Afifah Jihan Friskawati Hanapi Gita Potabuga Hamsidar Hasan Hamzah, Rosyidi Hayati, Rahmi Hiola, Faramita Hutuba, Ariani Ishak Isa Jafar La Kilo Jamiah Jamiah, Jamiah Julianty Akuba Juniarista Jessica Pakaya Kaino, Ratni Kasim, Sesha Ramadhani Khairil Pahmi Krisdianti, Nana La Ode Aman LATIF, MULTIANI S Liansyah Angga Saputra Mahdalena Sy Pakaya mahdalena sy. pakaya Makkulawu, Andi Maku, Mohamad Aditya Manno, Mohamad Reski Moh Adam Mustapa Mohamad Adam Mustapa Mohamad Aprianto Paneo Mohamad Reski Manno molote, kasibee molote Muh. Ihsan Muhamad Handoyo Sahumena Muhamad Handoyo Sahumena Muhammad Ricky Ramadhian Muhammad Rizal Firmanda Aditya Multiani S Latif Mursyidah, Andi Nana Krisdianti Nur Ain Thomas Nur Oktaviana Nur Rasdianah Nuri Suryani Nurul Istiqomah Panu, Karmila Papeo, Dizky Ramadani Putri Pradana, Riski Puluhulawa, Lisa Efriani Radjak, Fahmi As Rahmawati, Nuzu Ramadhan L, Aditya Rannu, Jumriani Riska Wahyuni, Nor Riski Pradana Robert Tungadi Selvi Marcellia Singgih Subiyantoro Siti Surya Indah Nurdin Sitti Gonibala, Sintia Suryadi, A Mu'thi Andy Suryadi, A. Mu'thi Andy Suryani, Nuri Teti Surriyati Tuloli Teti Sutriyati Tuloli Teti Sutriyati Tuloli Widy Susanti Abdulkadir Widy Susanti Abdulkadir Wiwin Rewini Kunusa Wiwit Zuriati Uno Yelisnawati Harwanto Zulfikar Ahmad