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All Journal Dinamika Hukum Jurnal Penelitian dan Pengembangan Pendidikan Journal of Aquaculture Management and Technology Jurnal Penelitian Pendidikan Guru Sekolah Dasar Al-Zahra : Journal for Islamic and Arabic Studies ADDIN QIJIS (Qudus International Journal Of Islamic Studies) Proceeding International Conference on Global Resource Conservation Jurnal Pendidikan Agama Islam JURNAL PENELITIAN LIBRARIA Edufisika: Jurnal Pendidikan Fisika Jurnal Pendidikan Islam Journal of Biology Education Madaniyah: Terciptanya Insan Akademis Berkualitas Dan Berakhlak Mulia Kesmas Indonesia: Jurnal Ilmiah Kesehatan Masyarakat JPM (Jurnal Pemberdayaan Masyarakat) TARBIYA ISLAMIA : Jurnal Pendidikan dan Keislaman JMM (Jurnal Masyarakat Mandiri) ORBITA: Jurnal Pendidikan dan Ilmu Fisika Paedagoria : Jurnal Kajian, Penelitian dan Pengembangan Kependidikan Journal of Teaching and Learning English Issues GENETIKA Britania Journal of English Teaching SYIRKAH Jurnal Dewantara Anterior Jurnal Jurnal Ilmu Pendidikan (JIP) STKIP Kusuma Negara Science Education and Application Journal JPPS (Jurnal Penelitian Pendidikan Sains) Jurnal Abdi Insani MALIA: Journal of Islamic Banking and Finance Jurnal Sains dan Edukasi Sains Jurnal Penelitian ADDIN Journal of English Teaching and Learning Issues Vocational : Jurnal Inovasi Pendidikan Kejuruan ISLAM NUSANTARA: Journal for the Study of Islamic History and Culture Al Hikmah: Journal of Education Civil Officium: Journal of Empirical Studies on Social Science INTERNATIONAL JOURNAL OF EDUCATION, INFORMATION TECHNOLOGY, AND OTHERS Jurnal Agroteknologi Journal of Educational Sciences JURNAL MUARA PENDIDIKAN JRFES Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS GEMBIRA (Pengabdian Kepada Masyarakat) InJEBA : International Journal of Economics, Business and Accounting EDUCATIA JURNAL PENDIDIKAN DAN AGAMA ISLAM Journal of Innovative Science Education Edukasia Islamika: Jurnal Pendidikan Islam Edubiotik : Jurnal Pendidikan, Biologi dan Terapan
Ulin Nuha, Ulin
State Institute for Islamic Studie (STAIN) Kudus
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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In silico Docking Reveals Interaction Pattern between Topoisomerase I and Camptothecin Analogs: Implication for Ovarian Cancer Treatment Nuha, Ulin; Mustofa, Zainul
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

Ovarian cancer is one of cancer types that begins in the ovaries. Many kind of anticancer agents are developed for the treatment now. Camptothecin analogs are agent that inhibit the action of DNA topoisomerase I, a nuclear enzyme that relaxes the supercoiled DNA during the replication, recombination, transcription, and repair of DNA. FDA have been approved two camptothecin analogs for the treatment of ovarian and colorectal cancer, those are topotecan and irinotecan. Another analogs are in various stages of clinical development, including 9-aminocamptothecin, rubitecan, lurtotecan, and exatecan mesylate. The purpose of this study is to discover interaction pattern between topoisomerase I and camptothecin analogs through in silico docking. PyRx is used for DNA topoisomerase I and camptothecin analogs docking. The interactions between topoisomerase I and camptothecin analogs were visualized and analyzed using PyMol and LigPlus. Our results show that the binding pattern between another camptothecin analogs, including rubitecan, lurtotecan, and 9-aminocamptothecin, with DNA topoisomerase I is relative similar with irinotecan-DNA topoisomerase I complex, specifically in the binding of Arg364, Asn491, Lys493 and Lys532.6 Keywords: camptothecin analogs; in silico docking; interaction pattern; ovarian cancer; topoisomerase I
Bioinformatic Analysis of Drug Candidate Compounds for Acquired Immunodeficiency Syndrome Sukoco, Restu Megadiana; Fauzi, Ahmad; Nuha, Ulin
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

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Abstract

AIDS is a syndrome caused by HIV. The immune system of AIDS patient was too weak to fight off many infections. Many drugs developed to overcome these deadly disease. In this study, bioinformatic analysis performed on some drug candidate compounds that under development of FDA for AIDS’ patient. The drug candidate compounds are Amdoxovir, Alovudine, Elvucitabine, Dexelvucitabine, Capravirine, Darunavie, Calanolide-A, Tipranavir and Enfuvirtide. Molinspiration and preADMET web server has been used as tool for analyzing that drugs. As a results, our study revealed that not all of these drug candidate compounds fulfilled the Lipinski’s rule of five and toxicity test standart in silico.Keywords:Bioinformatic analysis; AIDS’ drug; Lipinski’s rule; toxicity test
The Inventory of Aquatic Macroinvertebrates in Various Waterfall in East Region of Malang, East Java Wijayanti, Erna; Fauzi, Ahmad; Widiansyah, Arindra Trisna; Mustofa, Zainul; Setyanto, Haqqi Anajili; Sukoco, Restu Megadiana; Nuha, Ulin; Fadilah, Rizka Elan
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

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Abstract

Indonesia as Maritime Island has many water regions. Waterfall is one of the water region that has a large number of aquatic macroinvertebrates. The aim of this research is to collect and identify the various aquatic macroinvertebrates that can be found in several waterfalls in east Region of Malang, East Java. The research was carried out on September until November 2015 in six waterfalls: Coban Jahe, Coban Pelangi, Coban Trisula, Coban Kembar, Coban Ringin Gantung and Coban Pitu. Dragnet was used to collect the samplesof aquatic macroinvertebrates in some sampling point. The result of this research was found 38 families that belonged to 18 ordo in 6 different classes: Insecta, Oligochaeta, Gastropoda, Hirudinae, Turbellaria, and Crustacea. The information about the inventory of aquatic macroinvertebrates will give another suggestion for the local government to conserve this animals especially waterfall environment, not only as tourist area but also as a source of knowledge to do another research. Keywords: Aquatic macroinvertebrates; inventory; Malang; waterfalls
INTEGRASI PENDIDIKAN AGAMA ISLAM DAN PENDIDIKAN LINGKUNGAN DI PONDOK PESANTREN Nuha, Ulin
GENETIKA Vol 1, No 1 (2017): Genetika
Publisher : Tadris Biologi IAIN Kudus

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Abstract

Artikel ini membahas tentang integrasi ilmu yaitu Pendidikan Agama Islam dan Pendidikan Lingkungan. Hal ini sangatlah penting di ajarkan kepada santri dalam kegiatan pengajaran di Pondok Pesantren, sebagian orang menganggap bahwasannya ajaran agama tidak peduli terhadap lingkungan. Integrasi tersebut bertujuan untuk menanamkan nilai-nilai dasar dalam menjaga lingkungan alam yang terkandung dalam kitab suci Al-Quran. Dengan terjaganya lingkungan alam yang dilandasi oleh nilai-nilai agama dalam pendidikan lingkungan yang tertanam didalam jiwa peserta didik,diharapkan bisa memberikan pencerahan dan bisa mengurangi efek terjadinya kerusakan lingkungan dan pemanasan global yang di akibatkan perilaku manusia.Kata Kunci : Integrasi Pendidikan Agama Islam, Pendidikan Lingkungan
Javanese Ulama as a Part of Ulama Jawi Community and Their Connection with Ottoman Empire Nuha, Ulin
QIJIS Vol 5, No 1 (2017)
Publisher : STAIN Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21043/qijis.v5i1.2044

Abstract

16th century Javanese Muslim is like a newcomer in a large family called the Islamic civilization. At the same time, the Ottoman Empire at that time the great empire which emphasized Islam as a source of law is the only manifestation of the Islamic Caliphate remained. Is a must, Javanese Muslims who had entered the Islamic civilization met with the Ottoman Empire. Meetings that occur through several channels including the Hajj, political, trade and networking all these scientists actually have the benefit of both nations. Java clerics who are part of the community of clerics Jawi is the pioneer generation of meeting the other two nations in the continent.
THE ROLE OF PONDOK PESANTREN IN ENCOUNTERING ASEAN ECONOMIC COMMUNITY (AEC) Nuha, Ulin
ADDIN Vol 10, No 2 (2016): ADDIN
Publisher : LPPM IAIN Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21043/addin.v10i2.1739

Abstract

ASEAN Economic Community (AEC) with characteristics of the economy and labour liberalization can be a blessing for Indonesian people when they are ready to deal with it, but it can also be disastrous if they do not prepare it. This requires the synergy of government and all elements of Indonesian society in facing the ASEAN Economic Community (AEC). Boarding school in the context of history has become an institution that is highly effective not only in the printing community deeply in the science of religion, but also in terms of the economy certainly cannot remain silent in facing the ASEAN Economic Community (AEC).
MENINGKATKAN KUALITAS PELAYANAN PERPUSTAKAAN DENGAN PENDEKATAN BILINGUAL Nuha, Ulin
LIBRARIA Vol 2, No 1 (2014): LIBRARIA
Publisher : UPT. Perpustakaan Institut Agama Islam Negeri (IAIN) Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21043/libraria.v2i1.1190

Abstract

This article is aimed to describe how to improve the quality of library service with the bilingual approach. Good library service is service done quickly, on time, correctly, and with fun. Library sevice quality is the hallmarks of the library services that are expected to fulfi ll the users’ need. Library service with the bilingual approach is library service that utilizes the usefulness of two languages, Indonesian and English, in all service activities in a balanced way.The steps to improve the quality of service are strategic planning, user-oriented service, humanresource recruitment, provision of funds, and commitment.
Compatibility of Transactional and Interpersonal Conversation Texts in MTs English Textbook With The Standard of Content Nuha, Ulin
Jurnal Penelitian Vol 13, No 1 (2019): JURNAL PENELITIAN
Publisher : LP2M IAIN kUDUS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21043/jp.v13i1.4836

Abstract

In this study, I analyzed the transactional and interpersonal conversation texts found in grade VIII English textbook entitled “EOS English on Sky 2”. This textbook is still much used at SMP or MTs although it was published a couple years ago. I also analyzed the linguistic features of the transactional and interpersonal conversations in the English textbook. It is assumed by the writers of the English textbook that the transactional and interpersonal conversation texts found in the English textbook are compatible with the standard of content as mentioned in curriculum 2006, School-based Curriculum (KTSP or Kurikulum Tingkat Satuan Pendidikan). The standard of content in KTSP 2006 develops student’s linguistic competence in people’s experience, ideas, and feelings and understands various meanings.This study focuses on the issues of structural-functional approach which analyzes the speech function, structural approach which analyzes linguistic features,This is a qualitative study. In calculating the data and the final result of data percentage, quantification was used to support this study. The data are transactional and interpersonal conversation texts written in grade VIII English textbook. Units of analysis in this study are moves and clauses. The conversation texts are presented in 8 units. The moves were analyzed functionally and the clauses were analyzed structurally.The result shows that the speech functions of the transactional conversation texts are 54.5% matching the standard of content, the speech functions of the interpersonal conversation texts are 2.1% matching the standard of content, the linguistic feature applied in the transactional and interpersonal conversation texts uses the linguistic feature in functional literacy level, the speech functions of conversation texts introduced in EOS English on Sky 2 for MTs grade VIII are less compatible with the standard of content based on the compatibility levels.
Optimalisasi Peran Dewan Pengawas Syariah Pada Lembaga Keuangan Mikro Syariah (Studi Kasus di Assosiasi Koperasi Warga NU Jepara) Nuha, Ulin
MALIA: Journal of Islamic Banking and Finance Vol 2, No 2 (2018)
Publisher : IAIN Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21043/malia.v2i2.4940

Abstract

This study aims to find out the supervision carried out by the Sharia Supervisory Board, and try to analyze the role and function of the Sharia Supervisory Board in supervising shari'ah financial institutions, especially for ASKOWANU Jepara. This research is descriptive qualitative research, where data collection is carried out from various sources in the form of books, magazines, newspapers and documents related to the supervision of sharia financial institutions.The results of this study illustrate that basically the supervision of sharia financial institutions has two systems, namely supervision of aspects: (i) financial conditions, compliance with the provisions of financial institutions in general and prudential principles, and (ii) compliance with sharia principles in the operational activities of institutions Islamic finance. In this regard, the structure of supervision of sharia financial institutions is more multilayer in nature, which would ideally consist of a system of internal supervision carried out by Sharia Supervisory Board, which is more in-depth and carried out so that there are mechanisms and control systems for the interests of management and external supervision systems. by DSN which basically to meet the interests of customers and public interests in general.
PENGARUH PERBEDAAN DOSIS MADU DALAM PAKAN YANG MENGANDUNG rGH TERHADAP PERTUMBUHAN DAN RASIO JENIS KELAMIN PADA IKAN NILA (Oreochromis niloticus) Nuha, Ulin; Susilowati, Titik; Yuniarti, Tristiana
Journal of Aquaculture Management and Technology Volume 6, Nomor 3, Tahun 2017
Publisher : Journal of Aquaculture Management and Technology

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Abstract

Kebutuhan akan benih ikan nila juga tinggi untuk memenuhi target produksi. Beberapa cara telah dilakukan untuk menghasilkan ikan monoseks jantan, seperti penggunaan hormon 17α-metiltestosteron Akan tetapi, semakin sulit dan terbatasnya ketersediaan hormon tersebut, maka diperlukan bahan lain yang lebih mudah didapat dan lebih efisien dalam pemanfaatannya. Selain itu, diperlukan alternatif metode sex reversal yang lebih efektif dan efisien secara alami untuk menghasilkan benih ikan nila yang berkualitas. Cara untuk mendapatkan ikan jantan lebih banyak dapat dilakukan dengan metode sex reversal. Monoseks jantan dapat dilakukan melalui pemberian suplemen madu lebah hutan. Rekombinan hormone pertumbuhan (rGH) berfungsi mengatur pertumbuhan tubuh, reproduksi, sistem imun dan mengatur tekanan osmosis pada ikan teleostei. Pentingnya peneltian tentang jantanisasi menggunakan madu dalam pakan yang diberi rGH dalam upaya mendapatkan benih yang unggul, pertumbuhan cepat dan menghasilkan monoseks jantan. Tujuan dari penelitian ini adalah mengetahui pengaruh dosis madu terhadap pakan yang mengandung rGH terhadap pertumbuhan dan rasio jenis kelamin pada ikan nila dan dan mengetahui dosis madu terbaik dalam pakan yang mengandung rGH. Ikan uji yang digunakan adalah benih ikan nila larasati (Oreochromis niloticus) dengan bobot rata-rata 0,4 g/ekor dan panjang rata-rata 1,2 cm dengan padat tebar 80 ekor/wadah. Penelitian ini menggunakan metode eksperimental dengan Rancangan Acak Lengkap 4 perlakuan dan 3 kali ulangan. Perlakuan dalam penelitian ini: perlakuan A (dosis madu 0 ml/Kg pakan), B (dosis madu 25 ml/Kg pakan), C (dosis madu 50 ml/Kg pakan) dan D (dosis madu 75 ml/Kg pakan). Data yang diamati meliputi spesifik growth rate (SGR), food convertion ratio (FCR), total konsumsi pakan (TKP), survival rate (SR), presentase kelamin jantan dan kualitas air. Hasil penelitian menunjukkan bahwa perbedaan dosis madu dalam pakan yang mengandung rGH terhadap pertumbuhan dan rasio jenis kelamin pada ikan nila (O. niloticus) memberikan pengaruh sangat nyata (P<0,01) terhadap SGR, FCR dan  presentase kelamin jantan. Dosis terbaik perlakuan D mampu menghasilkan SGR, FCR masing-masing sebesar 9,81%/hari dan 1,75gram presantase kelamin jantan terbaik sebesar 81,11%. The need for tilapia fish too high to meet production targets. Several ways have been made to produce a male monosex fish, such as the use of hormone 17α-methyltestosterone, however, the more difficult and limited availability of these hormones, then needed another material that is easier to get and more efficient utilization. In addition, the necessary alternative methods of monosex more effective and efficient naturally to produce high quality tilapia fish. How to get more male fish to do with sex reversal method. Male monosex can be done through the forest bee honey supplementation in the feed which refers to the process of reproduction. Recombinant growth hormone (RGH) regulates body growth, reproduction, immune system and regulate the osmotic pressure on the fish Teleostei. The importance of other research about the use of honey in the feed masculinization by rGH in effort to obtain a superior seeds, rapid growth and generate monosex males. The purpose of this research is to know the effect of a dose of honey to feed containing rGH on growth and sex ratio on tilapia and honey and determine best dosage in feed containing rGH. Test fish used is larasati tilapia fish (Oreochromis niloticus) with an average weight of 0.4 g / head and an average length of 1.2 cm with a stocking density of 80 fishes / container. This research used experimental method to completely randomized design 4 treatments and 3 repetitions. The treatment in this study: treatment A (dose of honey 0 ml / kg of feed), B (dose of honey 25 ml / kg of feed), C (dose of honey 50 ml / kg of feed) and D (at a dose of honey 75 ml / kg of feed). Data observed specific growth rate (SGR), food convertion ratio (FCR), total feed consumption (TKP), survival rate (SR), the percentage of male and water quality. The results showed that the dose differences in feed containing honey RGH on growth and sex ratio in tilapia (O. niloticus) provides highly significant effect (P <0.01) on the SGR, FCR and percentage of male sex. Best dose treatment D is able to produce SGR, FCR respectively of 9.81%/day and 1.75gram presantase best male sex by 81.11%.
Co-Authors Abdillah, Fais Nur Abdul Azis Abdul Jalil Ainun Najib Amaliyah , Tsabitah Anjar Putro Utomo Anwar, Thoful Aprilia, Rennanti Lunnadiyah Arifudin, Moch. Safri Arindra Trisna Widiansyah, Arindra Trisna Aufaa, Muhamad Ibnu Abi Aulia Rahmawati, Aulia AZIZAH, DEWI HALIMATUL Billi Rifa Kusumah Budiawan, Ahmad Nafis Chin Chen, Yong Diah Wahyuni Dwipoyanti, Nur Atmi Ekawati, Nurul Elinah, Elinah Erna Wijayanti Eulis Henda Nugraha Fadillah, M. Amirul Faiza Salsabila FUADI, ILHAM Gito Supriadi, Gito Hanum, Wardah Nabilah Haqqi Anajili Setyanto, Haqqi Anajili Hasyim, Taufiqrahman Hawa, Putri Hidayat, Fayzabila Shofwa Huda, Aniq Nauval Husni Farros , Muhammad I Gusti Bagus Wiksuana I Ketut Mahardika ILMIAH, ULI TARBIATI Iskandar, Ali Khumairoh, Nurista Yuliatul Kusuma, Dhoni Kuswandari, Yuli Lisdiana Lisdiana Mahbubah, Isna Nikmatul Martin Martin Maulana, Rafika Anissa Moh. Nurul Qomar, Moh. Nurul Mohd Salleh, Sallimah Mubarok, Yusuf Muhamad Rizki Muhammad Izamul Maruf Al Fahmi Muhammad Nur Hayid Muharom, Mohammad Syahrul Mujianto Solichin Mushofi, Rfiul Muzadi, Ahmad Rafi Nasirun, Muhammad Khoirun Novianti, Teni Novitasari, Nurul Nur Ahmad, Nur Octaviani S, Nazhaa Patekun, Patekun Pramudya Dwi Aristya Putra Predina, Sherin Shintya Purwati Putri, Amelia Eka Rachmad, Ferizal Rahmawati, Rahmawati rakhmawati, ita Rasyid Ridlo, Zainur Razak, Ainun Ruzana Abdul Restu Megadiana Sukoco, Restu Megadiana Ridlo, Zainur Rasyid Ridwan Siskandar Risvana, Ivan Risvana Rizka Elan Fadilah, Rizka Elan Rizky Rizky, Rizky Rusdianto Rusdianto Rusdianto, Rusdianto Ruspendi, Ruspendi Safik Faozi, Safik Sari, Novilia Mita Sendi Setyawan, Ricky Andris Sri Wahyuni Sunarko, Mas Suparwi Supeno Supeno Susanti, Maya Syarif Maulidin Syauq, Muhammad Anas Titik Susilowati Tristiana Yuniarti Uma'iyah, Nofita Wardani, Veronica Diniarti Mulyana Kusuma Wicaksono, Iwan Yona Ratri, Anindhita Zainal Arifin Zainul Mustofa, Zainul Zam Zami, M. Akmalun Ni’am