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All Journal THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Analis Medika Biosains (JAMBS) JPP Jurnal Kesehatan Poltekkes Palembang Jurnal Ilmiah Tatengkorang International Journal of Advanced Health Science and Technology Jurnal Teknokes
Rahayuningsih, Christ Kartika
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Lead Levels in the Urine of Active Smokers and Passive Smokers in the Surroundings of Wadung Asri Sidoarjo Christyaningsih, Juliana; Sherly Amri, Qonita Salsabilla Amara; Rahayuningsih, Christ Kartika
International Journal of Advanced Health Science and Technology Vol. 3 No. 4 (2023): August
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i4.286

Abstract

An active smoker is someone who smokes cigarettes, resulting in an impact on their health, as well as on passive smokers and the surrounding environment. Smoking exposes individuals to the risk of lead inhalation due to cigarette smoke. Accumulated lead from smoked cigarettes can pose a health risk. This study aimed to identify respondent characteristics and analyze lead levels in both active and passive smokers. The research employed a descriptive approach with quantitative analysis. The sample consisted of urine samples from 20 active and passive smokers in the vicinity of Wadung Asri, selected using purposive sampling. The study was conducted at the Toxicology Laboratory, TLM Department of the Health Polytechnic in Surabaya, and at BARISTAND from October 2022 to May 2023. Based on the characteristics of active and passive smokers, regarding age, those aged 21-44 accounted for 25% of active smokers and 30% of passive smokers, those aged 45-59 constituted 10% in both categories, and those aged 60-74 constituted 15% of active smokers and 10% of passive smokers. The study results revealed that lead levels in the urine of active smokers ranged from a high of 0.1592 µg/mL to a low of 0.0885 µg/mL. Conversely, in passive smokers, lead levels in the urine ranged from a high of 0.0885 µg/mL to a low of 0.000032 µg/mL. Thus, the conclusion drawn from this study is that one respondent exhibited lead levels exceeding the normal threshold of <0.15 µg/mL.
KORELASI NILAI LAJU ENDAP DARAH (LED) DENGAN HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) PADA PEROKOK AKTIF DI WARUNG KOPI WILAYAH SURABAYA TIMUR Ramadhany, Rieke Dwi; Woelansari, Evy Diah; Rahayuningsih, Christ Kartika; Aprilyadi, Nadi
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 17 No 2 (2022): JPP (Jurnal Kesehatan Poltekkes Palembang)
Publisher : Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v17i2.1297

Abstract

Background Smoking has become one of the leading causes of death worldwide. The negative impact of smoking usually occurs after a few years when a person starts actively smoking can harm the body's organs and become a major risk factor for diseases with inflammatory components. Systemic inflammatory reactions are characterized by an increase in inflammatory cytokines, blood cell counts and blood viscosity. Examination CRP and ESR are the two most frequently measured laboratory tests in assessing the response of a systemic inflammatory process. This study aims to determine and analyze the correlation between ESR values ​​and hs-CRP in active smokers at coffee shops, East Surabaya. Methods: The type of research used is correlation research with cross sectional. The sample used is 30 active smokers who meet the inclusion criteria. This research was carried out on February 21 – April 11, 2022. The examination of ESR values ​​and hs-CRP levels was carried out at Balai Besar Laboratorium Kesehatan (BBLK) Surabaya. Results: It was found that 30 respondents had been actively smoking >5 years with a percentage of 100%. as many as 8 respondents consumed 1-10 cigarettes/day with a percentage of 27%, 19 respondents consumed 10-20 cigarettes per/with a percentage of 63%, and 3 respondents consumed >20 cigarettes/day with a percentage of 10%. The average value of ESR is 8.37 mm/Hr and The The average value of the of hs-CRP 1.11 mg/L. Conclusion: Based on statistical tests, There is no correlation between the value of ESR and hs-CRP in active smokers in a coffee shop in the East Surabaya area (p value = 0.099) with a sufficient relationship and a positive direction of relationship (r = 0.307).
AKSI KOMPETENSI BERSAMA DI PANTI ASUHAN MISI NUSANTARA SURAKARTA Juliana Christyaningsih; Puspitadewi, Teresia Retna; Alberta, Lembunai Tat; Pengge, Nuning Marina; Siagian, Hotmaida; Mutiarawati, Diah Titik; Rahayuningsih, Christ Kartika; Kurniawan, Dedi; Lestari, Indah; Sumasto, Hery; Endarini, Lully Hani; Kiaonarni OW; Ira Puspita Sari; Evi Yunita N; Suliati; Darjati; Nur Hatijah; Khambali; Hadi Suryono; Demes Nurmayanti; Tatarini Ika Pipitcahyani; Astuti Setiyani; Siti Alfiah; Dina Isfentiani; Bambang Hadi Sugito; Retno Sasongkowati; Yusianti Silviani; N. S. Widodo
Jurnal Ilmiah Tatengkorang Vol 7 No 1 (2023): Jurnal Ilmia Tatengkorang
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat, Politeknik Negeri Nusa Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54484/tkrg.v7i1.553

Abstract

Permasalahan sosial yang banyak terjadi di masyarakat adalah kaum marjinal yang terpinggirkan seperti anak terlantar, anak jalanan, pengemis, dan sebagainya. Salah satu upaya mengatasi masalah kaum marjinal yaitu dengan didirikan lembaga sosial berupa panti asuhan anak. Sejak masa pandemi, anak di Panti Asuhan Misi Nusantara Surakarta jarang mendapat layanan kesehatan dan ada keterbatasan ruang gerak anak-anak. Tujuan pengabdian masyarakat ini untuk membantu panti asuhan dalam memantau pertumbuhan dan perkembangan penghuni dan pengelola Panti Asuhan Misi Nusantara di Surakarta. Metoda pelaksanaan berupa pemeriksaan tumbuh kembang anak, Penyuluhan Hidup Bersih dan Sehat, pemeriksaan Status Gizi Anak, penyuluhan cara menyikat gigi yang benar, pemeriksaan kesehatan pengelola panti asuhan serta pelatihan penanggulangan bencana. Hasil pemeriksaan Kesehatan pada penghuni dan pengelola panti didapatkan sebagian besar (52,6 persen) penghuni panti berjenis kelamin laki-laki, hampir setengahnya berusia rata-rata 21-60 tahun, Sebagian besar (68,4 persen) tekanan darah kurang dari 140/90 mmHg, Sebagian besar (73,1 persen) berstatus gizi normal, hampir seluruhnya (94,4 persen) glukosa darah kurang dari 126 m/dL dan asam urat kurang dari 8 mg/dL. Secara umum keadaan warga panti asuhan dalam keadaan baik Social problems that often occur in society are abandoned children, street children, beggars, disabled people, neglected elderly, poor families, families with social problems, and so on. Children and poor people should have their human rights fulfilled by the State of Indonesia. However, in reality there are many children whose needs are not met, such as parents who are unable to provide for the child's needs or the child does not have parents. One effort to overcome this is to establish social institutions in the form of orphanages. Since the pandemic, children at the Mission Nusantara Surakarta Orphanage rarely receive health services and there is limited space for children to move. Theless than purpose of this community service is to assist the orphanage in monitoring the growth and development of residents and managers of the Mission Nusantara Orphanage in Surakarta. The implementation method is in the form of examinations on child growth and development, Counseling on Clean and Healthy Living, checking on the Nutritional Status of Children, counseling on how to brush their teeth properly, health checks for orphanage managers and training on disaster management. 6 percent) of the residents of the orphanage are male, almost half of them are aged 21-60 years, most (68.4 percent) have blood pressure less than 140/90 mmHg, most (73.1 percent) have normal nutritional status, almost all (94.4 percent) blood glucose less than 126 m/dL and uric acid less than 8 mg/dl. Similar activities are needed to see general body health and must be monitored periodically, so that the residents of the orphanage can find out their health status, especially now that they are still in a pandemic condition Covid-19
Penyimpanan dan Penambahan Kurma Ajwa Terhadap Aktivitas Antioksidan Infused Water Stroberi dan Wortel Dewi, Luh Putu Rahayu Candra; Lestari, Indah; Rahayuningsih, Christ Kartika; Diarti, Maruni Wiwin
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 1 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i1.274

Abstract

Radikal bebas merupakan senyawa yang sangat reaktif dan dapat merusak molekul pembentuk sel dalam tubuh sehingga terjadi kemunduran fungsi organ dan memicu timbulnya penyakit degeneratif. Infused water merupakan alternatif dalam proses detoksifikasi radikal bebas sekaligus pemenuhan kebutuhan cairan tubuh harian. Stroberi banyak dijadikan sebagai bahan utama infused water karena kandungan vitamin C yang tinggi dan dikombinasikan dengan wortel yang kaya akan beta karoten sedangkan kurma ajwa dijadikan sebagai penambah cita rasa. Kandungan antioksidan total dalam infused water mudah mengalami degradasi fisik maupun kimia selama proses penyimpanan. Penelitian ini bertujuan untuk mengetahui pengaruh penyimpanan dan penambahan kurma ajwa terhadap aktivitas antioksidan infused water stroberi dan wortel. Jenis penelitian yang digunakan adalah eksperimental dengan rancangan post test only control group design yang dilaksanakan di Laboratorium Proteomik Institute Tropical Disease Universitas Airlangga dan Laboratorium Kimia AMAMI Jurusan Analis Kesehatan Poltekkes Kemenkes Surabaya pada bulan Oktober 2019 sampai Juni 2020. Penelitian ini terdiri dari dua kelompok infused water dengan dan tanpa penambahan kurma ajwa yang disimpan selama 0 jam sebagai kontrol, 2 jam dengan pengisian ulang pertama dan 4 jam dengan pengisian ulang kedua pada suhu ruang (±28oC) dan suhu refrigerator (±10oC). Masing - masing sampel diuji aktivitas antioksidan menggunakan metode DPPH yang dinyatakan dengan IC50 sedangkan untuk uji organoleptik dilakukan secara hedonik oleh panelis. Hasil analisis ANOVA menunjukkan bahwa penyimpanan dan penambahan kurma ajwa berpengaruh nyata terhadap aktivitas antioksidan infused water stroberi dan wortel (p<0,05). Aktivitas antioksidan tertinggi diperoleh dari infused water dengan penambahan kurma pada penyimpanan suhu ruang selama 2 jam dengan nilai IC50 sebesar 206,53 ppm yang menandakan aktivitas antioksidan sedang.
Efektivitas Daun Kelor Terhadap Kadar Kadmium Dan LDL Kolesterol Dalam Darah Sebagai Indikator Penyempitan Pembuluh Darah (Aterosklerosis) Pada Tikus Putih Yang Terpapar Asap Rokok Rahayuningsih, Christ Kartika; Agustin, Riya
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 6 No 2 (2023): The Journal Of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v6i2.19837

Abstract

Tobacco consumption in Indonesia is a health epidemic that has direct or indirect toxicity due to exposure of cigarette smoke which contains harmful substances, especially cadmium metal. Cadmium’s exposure can increase the risk of coronary heart disease due to increased LDL cholesterol. One of the cadmium toxicity treatment by utilizing Moringa oleifera leaves as a natural antioxidant considering the flavonoids, saponins, ascorbic acid, carotenoids, phenolics, interquinones as cadmium chelating agents and β-sitosterol content. Therefore, it was necessary to determine the effectiveness of Moringa leaves extract in lowering blood cadmium and LDL cholesterol levels as indicators of atherosclerosis in white rats exposed to cigarettes smoke. The type of research was an experiment with quantitative analysis, conducted at the nutrition laboratory of the Faculty of Public Health Airlangga University and the clinical chemistry laboratory of Surabaya Health Polytechnic in March-July 2023. The independent variable was the doses of Moringa leaf extracts, while the dependent variables were blood cadmium and LDL cholesterol levels of white rats. The analysis of blood cadmium levels used an atomic absorption spectrophotometer and used precipitation methods by a photometer for LDL cholesterol levels. Based on statistical analysis using one way anova showed that blood cadmium levels had a significant value of < 0.05, followed by post hoc tests it was found that treatment group 2 had significant differences from normal groups. Moringa leaves extract dose of 1500 mg/kgbw has been effective in lowering cadmium and LDL cholesterol levels against the risk of atherosclerosis for 14 days. Keywords : Atomic Absorption Spectrophotometry, Cadmium, LDL Cholesterol, Moringa oleifera, photometer, Rattus norvegicus
Candida Albicans CT Value in Asthmatics with Prolonged Corticosteroid Inhaler Uses Cholidah, Ema Zahiroh Nur; Sasongkowati, Retno; Rahayuningsih, Christ Kartika; Suliati, Suliati
Jurnal Teknokes Vol. 16 No. 4 (2023): December
Publisher : Jurusan Teknik Elektromedik, Politeknik Kesehatan Kemenkes Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Corticosteroid inhaler is one of the first-line drugs given for the control and prevention of asthma attacks in the long term and continuously. The use of corticosteroid inhalers for a long time has systemic side effects in the oral cavity which can be a predisposing factor for normal fungal infection of Candida albicans microflora, an increase of Candida albicans’s amount in the oral cavity can cause oral candidiasis. Candida albicans detection using q-PCR to detect specific genes in oral swab specimens can provide an indirect picture of the amount of Candida albicans in the samples taken. The purpose of this study was to determine the relationship between the length of use of corticosteroid inhalers and the cycle threshold value in oral swab samples of asthma patient. This type of research is correlational research with data collection techniques using a purposive sampling technique on 30 respondents at the Lung Polyclinic at Bhayangkara Hospital H.S Samsoeri Mertojoso Surabaya who fit the inclusion criteria. Samples were examined using q-PCR to detect specific genes in the ITS-2 region to detect Candida albicans. This research was conducted at the Molecular Biology Laboratory of theMinistry of Health Surabaya Polytechnic during the period April – May 2023. The results showed that there were 26 samples(86.7%) positive for the ITS-2 gene and 4 samples (13.3%) negative for the ITS-2 gene. with sig. 0.307 so that it can be concluded that there is no relationship between the length of use of corticosteroid inhalers and the cycle threshold value of C. albicans in asthmatic’s oral swab sample.
Co-Authors Agustin, Riya Aprilyadi, Nadi Astuti Setiyani Bambang Hadi Sugito Cholidah, Ema Zahiroh Nur Darjati Dedi Kurniawan Demes Nurmayanti Dewi, Luh Putu Rahayu Candra Endarini, Lully Hani Evi Yunita N Evy Diah Woelansari Hadi Suryono Indah Lestari, Indah Ira Puspita Sari Isfentiani, Dina Juliana Christyaningsih Khambali, Khambali Kiaonarni OW Lembunai Tat Alberta, Lembunai Tat Maruni Wiwin Diarti Mutiarawati, Diah Titik N. S. Widodo Nur Hatijah Pengge, Nuning Marina Puspitadewi, Teresia Retna Ramadhany, Rieke Dwi Retno Sasongkowati Sasongkowati, Retno Sherly Amri, Qonita Salsabilla Amara Siagian, Hotmaida Siti Alfiah Suliati Suliati Suliati Sumasto, Hery Yusianti Silviani