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Synthesis of Microgel Sulfated Carboxymethyl Cellulose (SCMC) by Double Crosslinked Alginate from Lindur Fruit (Bruguiera gymnorrhiza) for Diabetic Ulcer Healing Hutapea, Jobin Armando; Zaki, Nesfitra Dzakwan; Syahrum, Silvina Faradilla; Putra, Surya Andika; Marbun, Sarah Aknesia; Tarigan, Indra Lasmana
Jurnal Rekayasa Kimia & Lingkungan Vol 20, No 1 (2025): Jurnal Rekayasa Kimia & Lingkungan (June, 2025)
Publisher : Chemical Engineering Department, Syiah Kuala University, Banda Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23955/rkl.v20i1.40112

Abstract

Microgels have been recognized as promising scaffolds for diabetic wound care due to their favorable properties in promoting wound healing. This study aims to synthesize a microgel using sulfated carboxymethyl cellulose (SCMC) derived from Lindur fruit (Bruguiera gymnorrhiza) for potential application in diabetic ulcer treatment. The synthesis was conducted through a double-crosslinking reaction, and the resulting microgel was characterized using infrared (IR) spectroscopy, scanning electron microscopy (SEM), and in vivo analysis in male mice (Mus musculus). The results demonstrated that the yield of Ca-alginate isolate ranged from 18.67% to 19.46%, with a purity of 19.5%33.1%, viscosity of 31.1931.46 cP, and stable pH at 7. The Ca-alginate isolate exhibited antioxidant activity at 50 ppm with an inhibition percentage of 22.3%. The modification of SCMC was successfully achieved, as confirmed by the presence of characteristic absorption peaks at 1220 cm (asymmetric SO stretching) and 870 cm (symmetric COS stretching vibrations), indicating successful sulfate group incorporation. The microgel swelling ratio was recorded at 660% for microgel A, 700% for microgel B, and 720% for microgel C, with microgel C exhibiting the highest swelling capacity. In vivo wound healing assessment revealed that microgel C facilitated more rapid wound closure, with wound sizes reducing progressively from 0.9 cm on day 3 to 0.5 cm on day 5, 0.3 cm on day 7, and 0.1 cm on day 14. These findings suggest that SCMC-based microgel with alginate derived from Lindur fruit holds significant potential as an innovative formulation for diabetic wound management
Pendampingan Ibu PKK Mengolah Kulit Pisang Menjadi Cookies Untuk Mendukung Pencegahan Stunting Fadhil, Ahmad; Rahmasari, Nadia; Tambunan, Betharia Juli Mas; Marbun, Sarah Aknesia; Rahayu, Rosi; Latief, Madyawati; Tarigan, Indra Lasmana
Jurnal IPTEK Bagi Masyarakat Vol 5 No 1 (2025)
Publisher : Ali Institute of Research and Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55537/j-ibm.v5i1.1267

Abstract

Indonesia merupakan salah satu negara penghasil pisang terbesar, namun kulit pisang yang kaya nutrisi sering kali terbuang sebagai limbah. Di sisi lain, stunting masih menjadi permasalahan kesehatan yang signifikan, terutama di wilayah Jambi. Kegiatan pengabdian ini bertujuan untuk memberdayakan ibu-ibu PKK Desa Simpang Limo dalam mengolah kulit pisang menjadi cookies sehat sebagai upaya alternatif mendukung pencegahan stunting. Program dilaksanakan selama tiga bulan (Agustus-November 2024) dengan melibatkan tiga puluh peserta. Metode yang digunakan meliputi observasi, sosialisasi, pelatihan pembuatan tepung kulit pisang, dan praktik pembuatan cookies berbasis kulit pisang. Hasil survei pasca-pelatihan menunjukkan tingkat pengetahuan yang sedang namun minat yang tinggi, di mana 36,9% responden menyatakan kesediaan memproduksi cookies kulit pisang dan 15,4% menilai inovasi ini sebagai langkah positif dalam pengurangan limbah. Produk cookies yang dihasilkan memperoleh respon positif, masyarakat menilai rasa enak, tekstur renyah dan aroma yang khas. Kegiatan ini menunjukkan bahwa pemanfaatan kulit pisang berpotensi menghasilkan produk pangan bergizi dan bernilai ekonomi, sekaligus meningkatkan keterampilan ibu PKK serta berpotensi mendukung upaya penurunan stunting.