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All Journal Jurnal Biologi Tropis Window of Health : Jurnal Kesehatan Journal Syifa Sciences and Clinical Research (JSSCR) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Dunia Farmasi Jurnal Ilmiah Manusia dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Aisyah : Jurnal Ilmu Kesehatan Journal of Pharmaceutical and Health Research International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Chemical Science and Technology Jurnal Kesehatan Tambusai Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Buana Farma Indonesian Journal of Pharmaceutical Education JUKESHUM: Jurnal Pengabdian Masyarakat FORTE JOURNAL Jurnal Farmanesia Journal of Health and Medical Science International Journal of Health and Pharmaceutical (IJHP) Student Scientific Creativity Journal Cross-border Jurnal Pengabdian West Science FARMASAINKES Nusantara Scientific Medical Research Journal Usada Nusantara: Jurnal Kesehatan Tradisional Jurnal Ilmu Kesehatan dan Gizi Journal of Pharmaceutical and Sciences. Scientica: Jurnal Ilmiah Sains dan Teknologi FASKES : Jurnal Farmasi, Kesehatan, dan Sains Medic Nutricia : Jurnal Ilmu Kesehatan Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara Jurnal Sains dan Kesehatan
Gabena Indrayani Dalimunthe
Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Al-Washliyah, Medan, Indonesia
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Transportation Veterinary Other

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Edge Activator: Effect of Concentration Variation of Tween 80 on Characteristics and Rate of Difusion transfersome sodium diclofenac Gabena Indrayani Dalimunthe; Ricky Andi Syahputra
Journal Syifa Sciences and Clinical Research Vol 3, No 2 (2021): Volume 3 Edisi 2 2021
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v3i2.11914

Abstract

Diclofenac sodium is a Transfersom is a transdermal delivery system consisting of phospholipids and edge activators. Transfersom increases the size of the stratum corneum lipid barrier pores, then enters the skin through the drive of the trans-barrier motion and squeezes itself to follow the lipid barrier pore size. The purpose of this study is to determine the effect of the tween-80 concentration as an edge activator on the characteristics and diffusion rate of diclofenac sodium transfersom. Transferom preparation used the vortex-sonication method which was made in five formulae with variations in the concentration ratio of phosphatidylcholine and tween-80 (95:05, 90:10, 85:15, 80:20, and 75:25). The results show that all five formulae have different morphological forms. The results of statistical tests using One-Way ANOVA finds a significant effect (p-value) of the edge activator concentration on the diffusion rate of diclofenac sodium transfersom.
NARKOBA, BAHAYA DAN CARA MENGANTISIPASINYA Ahmad Darwis; Gabena Indrayani Dalimunthe; Sulaiman Riadi
AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Vol. 1 No. 1 (2017): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LP2M UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v1i1.14

Abstract

Penyalahgunaan narkoba di kalangan pemuda dan remaja tidak dapat dipungkiri ternyata masih banyak yang mengkonsumsinya di lingkungan sekitar kita. Dampaknya bagi kesehatan dan masa depan tidaklah sedikit. Bahaya narkoba bagi pecandu dan kalangan muda, para pelajar sangat banyak dan jika tidak segera dihentikan kebiasaan mengkonsumsi narkoba maka hal ini akan memperburuk derajat kesehatan penggunanya itu sendiri secara pelan pelan tapi pasti serta akan merusak masa depan kehidupan mereka.. Dalam kehidupan bermasyarakat para pemuda atau pelajar membutuhkan suasana lingkungan yang kondusif dan nyaman dari penyalahgunaan narkoba, oleh karena itu penanggulangan narkoba menjadi tanggung jawab bersama dimulai dari keluaraga, kemudian masyarakat dan pemerintah. Melalui kegiatan pengabdian ini diharapkan mampu memberikan pemahaman kepada masyarakat di kabupaten karo tentang bahaya yangdiderita akibat penyalahgunaan narkoba , jenis jenis dan macam-macam narkotika serta bagaimana cara menanggulanginya. Metode yangdigunakan dalam menanggulangi narkoba adalah memberikan presentasi pemahaman yang benar tentang narkoba serta adanya diskusi tanya jawab seputar jenis jenis narkoba, bahayanya dan langkah langkah yang efektif agar masyarakat di Kabupaten Karo dapat menanggulanginya terlebih dahulu harus dimulai dari pribadi masing-masing keluarga, kemudian masyarakat dan pemerintah.
PKM PENYULUHAN PENGGUNAAN ANTIBIOTIK KEPADA MASYARAKAT DESA TEMBUNG Minda Sari Lubis; Debi Meilani; Rafita Yuniarti; Gabena Indrayani Dalimunthe
AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Vol. 3 No. 1 (2019): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LP2M UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v3i1.246

Abstract

Antibiotik merupakan obat yang penting digunakan dalam pengobatan infeksi akibat bakteri. Tingginya penggunaan antibiotika yang tidak tepat pada masyarakat disebabkan kurangnya pengetahuan tentang antibiotika yang menyebabkan meningkatnya masalah resistensi antibiotika. Pengabdian masyarakat ini bertujuan untuk melihat bagaimana tingkat pengetahuan masyarakat di Desa Tembung tentang penggunaan antibiotika. Pengabdian masyarakat ini merupakan Pengabdian masyarakat deskripsi, dengan metode pendekatan crosssectional, menggunakan instrumen berupa kuesioner. Total 30 responden dalam Pengabdian masyarakat ini adalah penduduk Lingkungan III, Kelurahan Tembung, Kecamatan Medan Tembung, Kota Medan. Hasil yang diperoleh dari pengabdian ini adalah peningkatan pengetahuan masyarakat di Desa Tembung entang penggunaan antibiotik yang tepat. Adapun Kesimpulan kegiatan ini adalah edukasi dan Penyuluhan dapat meningkatkan pengetahuan masyarakat tentang penggunaan antibiotika.
Formulasi Sediaan Gummy Candies Sari Brokoli (Brassica Oleracea L.) Dengan Variasi Sukrosa Sebagai Pemanis Niza Fonna, Gabena Indrayani Dalimunthe
Journal of Health and Medical Science Volume 1 Nomor 2 April 2022
Publisher : Journal of Health and Medical Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.828 KB)

Abstract

Broccoli belongs to the cabbage family and includes vegetables that are not resistant to hot air. Broccoli is efficacious to accelerate the healing of the disease and prevent and inhibit the development of cancer cells in the body, especially hormone-related cancers, such as breast cancer in women, and prostate cancer that threatens men. Therefore, it is very potential to be developed and made in gummy candies preparations so that consumers can be consumed for all ages (especially children). The objective of the research was to find out broccoli essence can be formulated into gummy candies with variations of sucrose as sweetener, test the quality of broccoli candies gummy candies preparations resulting from various physical tests and the results of the favorite level of gummy candies from broccoli essence with variations in sucrose levels as sweetener. In this research used formula 1 with the amount of sucrose levels 115 mg, formula 2 with the amount of sucrose levels 230 mg, formula 3 with the amount of sucrose content 345 mg, formula 4 with the amount of sucrose content 460 mg and formula 5 with the amount of sucrose levels 575 mg. Based on the results of the research, broccoli essence could be formulated into gummy candies preparations with sucrose variations, had an attractive shape and color with a distinctive odor, as well as a chewy texture and has a pH of 5 that was suitable for gummy candies, the results of the favorite level test showed formula 5 was the preferred one with a variation in sucrose levels of 575 mg. Variations in sucrose levels had an effect on the level of liking.
Formulasi Sediaan Gummy Candies Sari Sawi Pakcoy (Brassica Rapa L) Dengan Variasi Sukrosa Sebagai Pemanis Liza Zulaini, Gabena Indrayani Dalimunthe
Journal of Health and Medical Science Volume 1 Nomor 2 April 2022
Publisher : Journal of Health and Medical Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (198.807 KB)

Abstract

Pakcoy (Brassica rapa L.) is a type of green vegetable that is still a group with mustard. Pakcoy is a vegetable of immigrants from abroad. This vegetable is popular especially among people of Chinese descent. Sawi pakcoy contains vitamin A and vitamin C. The use of sawi pakcoy as a nutraceutical product is still relatively rare. The objective of this research was to find out that sawi pakcoy juice (Brassica rapa L.) can be made into preparations nutraceutical gummy candies and can find out which formula respondents prefer the most and the results of the best physical evaluation in gummy candies preparations. Samples of sawi pakcoy were formulated into gummy candies preparations with variations in sucrose concentrations of 115 mg, 230 mg, 345 mg, 460 mg, and 575 mg. All preparations were tested by organoleptic testing, weight uniformity, pH test, stability and hedonics by respondents of color, taste, aroma/smell, shape, and texture, then the results were compared to requirements in the literature. The results of the evaluation of gummy candies preparations state that gummy candies preparations meet physical quality. From the data it could be concluded that the preparation of gummy candies from sawi pakcoy’s essence showed the most preferred test results of gummy candies preparations, namely formula 5 with sucrose levels of 575 mg. The coefficient value of variation for the weight uniformity test was best compared to other formulas was formula 5 which was 575 mg. The pH value for the entire formula was 5. From stability tests it was known that the most stable formula was formula 5 which was stored at room temperature (25 °C).
Phytochemical Screening And Antioxidant Activity Testing Of Porang (Amorphophallus Muelleri Blume) Leaf Ethanol Extract From Kuta Buluh Region, North Sumatera Ainil Fithri Pulungan; Ridwanto Ridwanto; Gabena Indrayani Dalimunthe; Zulmai Rani; Rahma Dona; Ricky Andi Syahputra; Robiatun Rambe
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.501 KB) | DOI: 10.51601/ijhp.v3i1.141

Abstract

Porang (Amorphallus muelleri Blume) is one type of tuber plant that has the potential to be developed in Indonesia. Porang plants have been reported to contain chemical compounds that have antioxidant activity. This research was conducted on the leaves of the porang plant with the aim of knowing the antioxidant activity, characterization, and phytochemical profile of the compounds contained therein. Compound identification and characterization were performed using standard methods, and antioxidant activity was determined using the DPPH (1,1- Diphenyl-2-picrylhydrazyl ) method. The results of the identification of chemical compounds showed that the ethanol extract of porang leaves contained chemical compounds of alkaloids, flavonoids, tannins, saponins, and steroids. The results of the examination of the simplicia characterization of porang leaves included the soluble ethanol content of 33.93%, the water soluble extract content of 17.3%, the ash content of 5.58%, the acid insoluble ash content of 0.235% and the water content of 8%. From the results of the simplicia characterization, it shows that the results meet the specified requirements. The results showed that the ethanol extract of porang leaves had antioxidant activity with an IC50 value of 93.04 µg/mL, which in this case is included in the category of strong antioxidant activity. Meanwhile, as a comparison, Vitamin C was used, which has an IC50 value of µg/mL, which is included in the category of very strong antioxidant activity.
Antipyretic Activity Test of Combination of Peperomia pellucida Extract and Andrographis paniculata in Mice (Mus musculus) Khairil Pahmi; Muhammad Ricky Ramadhian; Gabena Indrayani Dalimunthe
Indonesian Journal of Pharmaceutical Education Vol 2, No 3 (2022): September-Desember 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i3.15654

Abstract

Pepper elder (Peperomia pellucida) and green chiretta (Andrographis paniculata) are plants that have been used empirically to reduce fever. Fever is a symptom of a disease characterized by a significant increase in body temperature. This study aimed to determine the antipyretic effect of the combination of pepper elder herbal extract (P. pellucida) and green chiretta herbal extract (A. paniculata) (80:20) in the male house mice (Mus musculus). Extraction was conducted through maceration using ethyl acetate solvent. The total of 25 male mice were divided into 5 groups, namely a negative control group (Na-CMC 1%), a positive control group (paracetamol), and a treatment group induced by a combination of pepper elder herbal extracts and green chiretta herbal extract at the dose of (80 + 20), (40 +10), and (20 + 5) mg/kg BW. DPT vaccine 0.2 ml was used intramuscularly as a fever inducer. The observation was carried out at 30, 60, 90, and 120 minutes after treatment. The data obtained were analyzed using one-way ANOVA followed by the LSD test to determine the differences between groups. The results showed that variations in the dose of the combination of pepper elder and green chiretta herbal extracts had an antipyretic effect where the most effective dose was (80 + 20) mg/kg BW due to its stable temperature reduction power and effectiveness that are equivalent to paracetamol. The combination of suruhan herb extract (P. pellucida) and sambiloto herb (A. paniculata) has potential as an antipyretic
Formulation And Evaluation Of The Preparation Of Hard Candy Source Of Sweet Orange (Citrus Sinensis (L.) Osbeck) As A Nutracetical Syarifah Mauliza; Gabena Indrayani Dalimunthe
International Journal of Science, Technology & Management Vol. 3 No. 5 (2022): September 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i5.611

Abstract

Candy is used as a source of high calories, so it is often eaten during activities such as work, studying, and exercise. In general, the candy that is widely circulated in the community is hard candy, which has a hard texture and a shiny appearance. The benefits of candy for the human body are that it adds nutrients, minerals, and other vitamin content because this candy is made from real fruit juice. The purpose of this study was to formulate hard candy with the main ingredient of sweet orange juice with a variety of sucrose in order to get a delicious formula in the form of taste that is expected to meet the nutritional requirements of both children and adults. formulated candy. Hard candy is made using the open pan method. The research is experimental and includes the processing of sweet orange ingredients, making sweet orange juice, making hard candy and hard candy test parameters including organoleptic tests, pH tests, weight uniformity tests, water content tests, ash content tests and tests of preference level (hedonic test) by the respondent. Based on the results of the study, sweet orange juice can be formulated into hard candy preparations with sucrose 1,5; 2 and 3 g. The obtained results with candy shape, taste, and hardness are quite good; they have a pH of 5, and they meet weight uniformity requirements with a coefficient of variation of 1.08, 1.30, and 1.11%, moisture content 2.4, 2.3 and 1.7%, ash content 1.0, 0.13 and 0%. The results of the organoleptic preference level test in terms of liking, taste, and texture showed that F3 was the most preferred formula. The sucrose levels have an effect on the level of liking.
Caffeine Levels from Various Types of Coffee Drink Packaging Circulated in the Medan City Market Were Examined Using a UV Spectrophotometry Method Gabena Indrayani Dalimunthe; Adli Nuzula Rahmah; Zulmai Rani; Yayuk Putri Rahayu
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 5, No 2 (2022): JULI 2022
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v5i2.37465

Abstract

Coffee drinks are drinks that come from the processing and extraction of coffee beans. One of which is caffeine. Coffee contains approximately 24 of the most important substances. The purpose of this study was to determine the level of caffeine in coffee drinks from various types of packaging. The research stages include sample collection and preparation; identification of caffeine content; and examination of caffeine levels using UV spectrophotometry. The results showed that the three samples of coffee drinks sold at the minimarket in Jermal, Medan contained caffeine, and the levels of caffeine in coffee drinks were 26,352±0,292 mg/100mL (Sample A), 15,179±0,286 mg/100mL (Sample B), and 7,965±0,98 mg/100mL (Sample C). The caffeine content obtained meets the requirements of SNI, where the maximum amount of caffeine that can be consumed by the public in a day based on SNI is 50 mg–150 mg.
Aktivitas Antibakteri Ekstrak Etanol Lidah buaya (Aloe Vera L.) Terhadap bakteri Propionibacterium acnes Sry Lanna Zahara, Minda Sari Lubis, Gabena Indrayani Dalimunthe, Haris Munandar Nasution
Journal of Health and Medical Science Volume 1 Nomor 2 April 2022
Publisher : CV. Pusdikra Mitra Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tanaman Lidahibuaya (Aloeivera L.) di Indonesia telah lamaidibudidayakan olehimasyarakat sebagaiitanaman obat keluargaisekaligus tanamanihias karenaibentuknya yangiunik. Lidahibuaya diketahui mengandung antrakuinon, saponin dan tanin yang memiliki sifat antibakteri. Kulit luar dan tengahibanyak mengandungiantrakuinon yangimemiliki efek antibakteri, sedangkanikulitidalam mengandung saponin yang juga memiliki efek antibakteri. Penelitianiini bertujuan untukimengetahui bahwa ekstrakietanol lidahibuaya memiliki kemampuan menghambatidan membunuhibakteri Propionibacteriumiacnes. dibuat secara maserasi dengan etanol 96%, kemudian dilakukan skrining fitokimia terhadap ekstrak. Ekstrakietanol lidah buayao(Aloe veraiL.) dibuat dalamilarutan uji konsentrasi yangiberbeda yaitu 3,125%,i6,25%,i12,5% dan 50%.iKontrol positifiyang digunakaniadalah tetrasiklin danikontrol negatifnyaiadalah DMSO.Hasil penelitian menunjukkanibahwa ekstrakietanol lidahibuaya mengandung flavonoid,osaponin, tanin, steroid/triterpenoididan antrakuinon. Konsentrasi hambat minimum (KHM)pditentukanidengan mengamati kekeruhanisecaraiin vitro danikonsentrasiibunuhiminimum (KBM) ditentukan dengan menghitung keberadaan koloni Propionibacterium acnes dalam cawan Petri. Berdasarkanipenelitian yang dilakukanidapat disimpulkanibahwa ekstrakietanol lidahibuaya mampu menghambatipertumbuhan Propionibacterium acnes pada konsentrasi 12,5% sebagai hambat minimum dan pada konsentrasi 25% sebagai bunuh minimum
Co-Authors Adani, Bazlina Adela Octi Dwiyani Adli Nuzula Rahmah Agustina, Meri Ahmad darwis Ali Affan Silalahi Alma Dhita Shafira Anny Sartika Daulay Anugrah, Bayu Arianti, Sellin Arina Ashar, Diya Asparyzha, Rhyzha Athaillah Athaillah Aulia Fitri, Aulia Aulia, Meisyah Bambang Hermanto Basaniah Basaniah Chairina Milda Chandra, Putra Cindy Marlina Tambunan Claudy Friesta Melanie Cut Erika Maulydya D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D.Elysa Putri Mambang Debi Meilani Dewa, Fasca Dikki Miswanda Dina Veranika Dinda Sari Utami Emmy Wiriandini Fadillah, Nike Fathur Rahman Febiyani, Rica Fithri Pulungan, Ainil Fitri Febriani Fitri, Raissa Ginting, Ovalina Sylvia Br. Girsang, Raflika Azwanda Gita Dwi Puspa Fadillah Hamda, Haikal Handayani, Riska Harahap, Aswan Pangondian Haris Munandar Nasution Hendraputra, Hardy Handoko Heru Adha Prayogo Hijrotun Nur Humairah, Dwina Angelina Husna, Miftahul husna, nadiatul Ilmi Widya Sari Intan Annisa Puteri, Cut Isnaria, Vita Jurida, Wike Juwita, Sukma Karlina Butar Butar Kartika, Dinda Dwi Khairil Pahmi Khairunnisa , Ardina Kiki Rawitri Latifah Sahara Pulungan Laura Indah Restu Sihotang Lestari, Amanda Putri Linda, Rosa Lisa Amalia Lubis, Minda Sari M. Arya Wiguna Madani Sirait maghfirah, Suci Mambang, D Elysa Putri Mambang, Elysa Putri Misna Rosalinda Hutabarat Muhammad Amin Nasution Muhammad Ricky Ramadhian Muhammad Tegar Tri Rizky Mutia Dena Nasution, M. Pandapotan Nasution, Nur Sahadah Nasution, Shamila Sufi Aulia Nasution, Vevi Sarah Nia Novranda Pertiwi Nindya Indah Damayanti Ningtias, Anggitha Niswa, Khairun Novita Sari, Helsa Nur Aini Khairunnisa Nur Asia, Nur Nuraisyah Nurfadilla, Kiki Nurliansyah, Nurliansyah Nurmala, Dewi Nurul Hidayah Nurul Salsa Abya Ritonga Olita, Apen Ovalina Sylvia Br. Ginting Peri , Peri Peri, Peri Puteri, Cut Intan Annisa Putra Chandra Rafita Yuliarti Rafita Yuniarti Rafita Yuniarti Rafita Yuniarti Rafita Yuniarti Rahma Dona Rahma Maulidia Fitri Rambe, Robiatun Rambe, Sitiapsah Rangkuti, Cindy Rahayu Rawitri, Kiki Riani, Nur Aslin Ricky Andi Syahputra Ricky Andi Syahputra Ridwan Taher Lubis Ridwanto Ridwanto Rima Marwarni Rina Azhari Risnayanti Rista Rafliza Ritonga, Oktavia Riza Syafira Robiatun Rambe Rosalinda Mahdalena Sinaga Rosalinda Mahdalena Sinaga Saddam Husein sahrianti, Hikmah Samosir, Anzly Hasian Samran, Samran Saragih, Aqilah Mutmainnah Sari Lubis , Minda Sari Lubis, Winda Sartika Daulay, Anny Selvicahyani, Selvicahyani Seri Lestari Shinta Mida Ariani Harahap Sinaga, Rosalinda Mahdalena Siregar, Hikmatussabaria Siti Anisa Siti Anisa Sitinjak, Iyustri Ririn Situmorang, Lusi Grasia Sri Indah Lestari Sri Mulia Ningsih Siregar Sri Wahyuni Sri Wahyuni Sulaiman Riadi Sulwiyatul K Sani Syahputri, Maulida Syarifah Aulia Syarifah Mauliza Syilvi Rinda Sari Tasya Ardana Ulfa Rahmi Ummu Safura Sirait Widya Sari Winda Aulia Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Apriani Br.Lubis Yuni Sartika Yuniarti, Rafita Yuniarti, Rapita Zahara, Anisa Zahira Ahmad, Madani Ziza Putri Aisyia Fauzi Zulmai Rani