Number of deaths from the deadliest pandemics/epidemics in history worldwide as of 2025 (in millions)

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Release date

July 2025

Region

Worldwide

Survey time period

as of 2025

Supplementary notes

* Figures for COVID-19 are as of May 2024 and taken from a different source. The figures can be found here.

** This is an exact estimate.

Citation formats

Deadliest disease outbreaks in history worldwide as of 2025

Published by
Conor Stewart,
Mar 3, 2026

From around 1334 to 1353, the Black Death claimed the lives of between ** and *** million people worldwide, making it the deadliest disease outbreak in human history. Although the exact death toll from the COVID-19 pandemic is difficult to judge, sources such as the World Health Organization (WHO) and the Economist estimate that as of May 2024, between ** and ** million people may have lost their lives due to COVID-19. However, as of June 2025, the WHO reported just over ***** million confirmed deaths due to COVID-19 worldwide. This statistic presents the number of deaths from the deadliest pandemics/epidemics in history.

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