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Separation processes

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Separation processes are techniques used in chemical engineering and industrial processes to separate components of a mixture based on differences in their physical or chemical properties. These processes are essential for purifying substances, recovering valuable materials, and facilitating various applications in industries such as pharmaceuticals, petrochemicals, and food processing.
lightbulbAbout this topic
Separation processes are techniques used in chemical engineering and industrial processes to separate components of a mixture based on differences in their physical or chemical properties. These processes are essential for purifying substances, recovering valuable materials, and facilitating various applications in industries such as pharmaceuticals, petrochemicals, and food processing.

Key research themes

1. How can gravity-driven separation techniques be optimized and diversified for mineral and particulate separation?

This theme focuses on classical gravity separation methods and their recent innovations, emphasizing the optimization of operational parameters and adaptation to finer particle recovery and hard rock mineral processing. This research area matters because gravity separation remains a cost-effective and environmentally friendly technique, yet faces challenges in fine particle separation and operational control, necessitating advances in equipment design and process understanding.

Key finding: This paper provides a detailed comparative review of main gravity separation devices, highlighting new equipment such as In Line Pressure jigs that operate under elevated pressure (~70 kPa) for compact operation and minimal... Read more
Key finding: The research models the effect of preliminary stratification of grain mixtures before entering vertical pneumatic separators to enhance separation of light impurities by creating layers enriched in these impurities. The study... Read more
Key finding: By decoupling thermal gradients from convective velocity in a horizontal cavity filled with binary fluid, the study analytically and numerically determines optimal parameters (mass Péclet and Rayleigh numbers) for maximizing... Read more

2. How can integration of reaction and separation processes in a single unit improve efficiency and control in chemical manufacturing?

This theme explores reactive separation processes combining chemical reactions and separation in unified equipment such as reactive distillation columns, focusing on control strategies to manage inherent nonlinearities and operational constraints. Approaches in process integration aim to reduce energy consumption, equipment footprint, and waste production while ensuring product quality. Understanding and implementing advanced control methods like Model Predictive Control (MPC) is critical to handle complex interactions, maintain stability, and optimize performance in these integrated systems.

Key finding: This study demonstrates the application of advanced nonlinear Model Predictive Control (MPC) strategies to reactive separation processes, specifically natural gas sweetening, which intrinsically exhibit nonlinear dynamics due... Read more

3. What are the advances in membrane-based and supported separation technologies for energy and environmental applications?

This area investigates novel membrane materials and supported systems that enable selective separation of gases (e.g., CO2 from flue gases, olefin/paraffin separations) or contaminants (e.g., antibiotics from wastewater). Enhanced materials such as mixed matrix membranes incorporating functional nanomaterials aim to overcome trade-offs between permeability and selectivity, while supported ionic liquid membranes offer high extraction efficiency with tunable selectivity. Molecular-level understanding of transport mechanisms guides material design. These efforts address energy efficiency, environmental sustainability, and industrial applicability of membrane-based separation.

Key finding: This comprehensive review delineates state-of-the-art CO2 separation technologies including adsorption, absorption, membrane-based and cryogenic distillation processes, contrasting their operational efficiencies, energy... Read more
Key finding: The study fabricates mixed matrix membranes (MMMs) incorporating hydroxyl-functionalized graphene nanosheets into a Pebax 1657 polymer matrix, achieving enhanced propylene permeability (~90 barrer) and selectivity (C3H6/C3H8... Read more
Key finding: This work optimizes supported ionic liquid membranes (SILMs) employing Aliquat 336 as carrier embedded in PVDF supports for selective extraction of sulfamethoxazole (SMX) antibiotic from aquaculture wastewater. The SILM... Read more

4. How can the application of chemometrics improve data analysis and method optimization in separation science and related forensic/toxicological analyses?

With increasingly complex and rich datasets from multi-dimensional separation techniques (e.g., chromatography), chemometric approaches—multivariate analysis, experimental design, pattern recognition—enable extraction of meaningful information, enhanced method development, and better decision-making. This theme covers applications in analytical chemistry including volatile, soluble, and colloidal samples and extends to forensic and toxicological contexts where data robustness, automation, and reliable interpretation are critical for regulatory and legal purposes.

Key finding: This review synthesizes the role of chemometric techniques—such as PCA, cluster analysis, LDA, PLS, and experimental design—in improving data elaboration and method design in separation science. Applications across gas... Read more

5. How can modeling and predictive analytics accelerate the selection of separation media and process parameters for biotherapeutics and metallurgical applications?

This theme focuses on developing predictive models and software tools using physicochemical property inputs to expedite and optimize separation media selection and process design, minimizing experimental resource usage. Examples include surface-property based prediction of monoclonal antibody behavior on hydrophobic interaction chromatography resins and web-based automated sizing tools for multiphase separators in oil and gas. These modeling approaches enhance efficiency, accuracy, and reliability in designing separation processes critical for pharmaceutical manufacturing and hydrocarbon processing.

Key finding: Using a dataset comprising seven mAbs across 13 HIC resins paired with measured physicochemical attributes (e.g., surface hydrophobicity, charge, thermal stability), this study develops QSAR-based predictive models with high... Read more
Key finding: This proposal outlines the development of 'Separator Pro', a web-based software integrating advanced engineering algorithms with user-friendly interfaces for automated selection and sizing of multiphase separators (horizontal... Read more

6. What are the emerging materials and process developments for enhanced adsorption-based removal of organic and biological contaminants from wastewater?

This research theme explores the design and characterization of novel adsorbent materials modified with polymers or functional groups to improve adsorption capacity, selectivity, and regeneration for contaminants such as pesticides, antibiotics, and dyes in aqueous environments. The optimization of surface chemistry, porosity, and interaction mechanisms is critical for achieving efficient contaminant removal while ensuring reusability and operational feasibility. Understanding adsorption kinetics and isotherms under various conditions guides development of sustainable wastewater treatment technologies.

Key finding: This study synthesizes granular activated carbon (GAC) modified with polyethylene glycol (PEG) and evaluates its performance for adsorption of Diazinon (DZ), Amoxicillin (AMX), and Crystal Violet (CV) from aqueous solutions.... Read more

All papers in Separation processes

Extractive Distillation Process 297 8.3 Applications to screening of solvents 303 8.4 Extractive and Ordinary distillations Canpared 306 8.5 Further Discussion of the results on Screening of Solvents 315 9 DESIGN METHODS AIID THE COMPUTER... more
Columns 492 LC TROUBLESHOOTING Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part 2: Contemporary Separations of Proteins by Size-Exclusion Chromatography Szabolcs Fekete, Davy Guillarme, and Dwight R. Stoll Several... more
In our previous work, a perturbed hard-trimersphere equation of state (PHTS EOS) was developed for modeling the phase equilibria of pure ionic liquids (ILs) (M.M. Alavianmehr et al., Ionics 22 (2016) 2447-2459). In this work, we have... more
Gas separation technology is a mature topic, while the vapor permeation (VP) process still needs some development. It can be presumed that VP will become extensively applied in the future, thanks to its economic and ecological advantages.... more
Molecular sieves can be used as a host matrix to encapsulate several drugs. Here, we studied the adsorption of acetylsalicylic acid (ASA) in HUS-Y, HZSM-5 and silicalite-1 zeolites, as well as in the mesoporous sieve Si-MCM-41, and... more
The preparation and characterization of porous ceramics multilayer ultrafiltration membrane is described. The first step consisted to prepare high-quality macroporous support in Moroccan clay. The choice of this material is based on its... more
Niniejszy artykuł traktuje o trudnościach metodologicznych i koncepcyjnych dotyczących fundamentalnych dla lingwistyki wyrazów znak i tekst oraz wiązanych z nimi (meta)lingwistycznych pojęć. Przyczynę tych trudności stanowi wyłączanie z... more
This is to certify that the thesis entitled "DI-OCTYL AMINE MEDIATED TRANSPORT OF LIGNOSULFONATE USING BULK LIQUID MEMBRANE TECHNIQUE" submitted by Mr. SANTOSH VISHWANATH HIPPALE to National Institute of Technology, Rourkela, India for... more
This is to certify that the thesis entitled "DI-OCTYL AMINE MEDIATED TRANSPORT OF LIGNOSULFONATE USING BULK LIQUID MEMBRANE TECHNIQUE" submitted by Mr. SANTOSH VISHWANATH HIPPALE to National Institute of Technology, Rourkela, India for... more
Superoxide dismutase (SOD) is a major antioxidative enzyme and the only one that neutralizes superoxide ion, a precursor of reactive oxygen species (ROS) and their reactive derivatives. ROS can cause considerable damage to biological... more
Chromatographic retention data were measured for a wide range of organic solutes on 1-butyl-1-methylpyrolidinium tris(pentafluoroethyl)trifluorophosphate, ([BMPyrr] [FAP]
Propylene is a widely used compound in various indus trial applications, but its separation from propane, which is often associated with it, remains a significant challenge. Among the separation methods, membrane technology, particularly... more
A new model to obtain fast prediction of partition coefficients in polymer/polymer aqueous two phase systems (ATPSs) is presented, using amino acids as test systems. In particular, the partitioning behavior of eleven amino acids (glycine,... more
A phase diagram was constructed from experimental data to study the phase behavior of the liquid-liquid ternary system of acetone, ethyl acetate, and water in a solution. To achieve this, the following objectives are assigned: (1) to... more
A comprehensive outlook of marriage and divorce in the 21st century. This book looks at marriage from different cultures around the world and the realities and challenges faced by couples. It looks at the perspective of marriage from the... more
Evaporation-driven particle self-assembly can be used to generate three-dimensional microstructures. We present a new method to create these colloidal microstructures, in which we can control the amount of particles and their packing... more
Zanieczyszczenie środowiska wodno-glebowego substancjami ropopochodnymi wynika z powszechnego zastosowania ropy naftowej i jej pochodnych, jako podstawowego surowca do produkcji energii, w przemyśle chemicznym, w zakładach przemysłowych... more
Literature data with respect to Ni(II) adsorption from real process streams is scarce. The present work addresses the effect of solution complexity of electroless plating solution on the adsorption efficiency of commercial activated... more
This paper focuses on methane recovery from gas hydrates and the thermal assisted CH 4 -CO 2 replacement in the hydrate phase. The experimental investigation was carried out in a 60 L reactor, in which the CH 4 hydrates were formed with... more
Nano goethite was synthesized via chemical precipitation, characterized, and utilized in batch adsorption of uranium (VI) in aqueous solution. This study aims to investigate whether a synthetic goethite could extract uranium (VI) from... more
A hybrid purification process combining extraction and distillation for the production of levulinic acid (LA), furfural, and formic acid (FA) from lignocellulosic biomass was studied. The effective process depends on the choice of... more
Separator sizing is a critical process in the oil and gas industry, directly impacting the efficiency, safety, and reliability of operations. Existing tools often fail to meet the requirements of accuracy, flexibility, and usability.... more
The number of sovereign states has more than quadrupled since 1939. Meanwhile, there are about 50 small political units in the World in some form of dependency, and for that reason, possible candidates for new and small, independent... more
Abstract: The fruits of Zanthoxylum leprieurii Guill. & Perr. (Rutaceae) are traditionally used in Africa, particularly in Cameroon, as a spice and in the treatment of sickle cell anaemia. Phytochemical investigation on the fruits of this... more
At the moment the combined method - mash distillate rectification with following water adsorption by molecular sieves - is the most widely used method in bioethanol dehydration. We have estimated the energy consumption of the both water... more
Lactic acid is an important platform chemical with a wide range of applications. Production of lactic acid by fermentation is advantageous because renewable and low cost raw materials can be used as substrates. After fermentation, the... more
Monoclonal antibodies (mAbs) require a high level of purity for regulatory approval and safe administration. Highmolecular weight (HMW) species are a common impurity associated with mAb therapies. Hydrophobic interaction chromatography... more
Future high value lignin-based products, such as carbon fibers, require a lignin raw material with a high purity level. Lignin with low inorganic content can be separated from kraft black liquor by the LignoBoost process. This laboratory... more
Produksi biji pinang sangat melimpah, dimana selama ini potensi biji pinang sebagian besar hanya digunakan untuk keperluan menyirih (nyeupah). Biji pinang sebagai penyusun ramuan obat sudah masuk kedalam prioritas WHO (World Health... more
To effectively remove Diazinon (DZ), Amoxicillin (AMX), and Crystal Violet (CV) from aquatic environments, a novel granular activated carbon (GAC) modified with Polyethylene glycol 600 (PEG) was created and manufactured. The chemical... more
Worldwide demand for cleaner burning fuels and 'clean'chemicals has been increasing from the global issues of environmental concern. This lead to a greater utilization of renewable resources to replace the old and existing... more
Lactic acid is a naturally occurring organic acid that can be used in a wide variety of industries, such as the cosmetic, pharmaceutical, chemical, food, and, most recently, the medical industries. It can be made by the fermentation of... more
Olive mill wastewater (OMW) causes many environmental problems, mainly in the Mediterranean area. The phenolic content of OMW is principally responsible for the phytotoxicity and microbial growth inhibitory effects. However, these... more
This work presents statistical data on breast cancer incidence in the population of the USSR and the Union republ i c~ (1970-1980). Mortality rates for the population are also presented, together with trends in compilation of breast... more
The history of mass transfer dates back to the 19th century with the development of diffusion theory. Initially, operations like distillation, drying, and leaching were practiced as an art. The 1920s brought advancements with the film... more
During the thickening process of sludges with intermediate to high solid concentrations three settling regimes are typically encountered, namely, zone, transition, and compression regimes. Recent studies have indicated that the validity... more
Hydroelectricity is an important component of world renewable energy supply and remains a major source of power generation due to its environment friendly nature. Effective water management improves the efficiency of utilization of... more
This work presents a theoretical investigation of the use of nanoporous carbon membranes for the separation of nitrogen from natural gas. A mathematical model to predict the performance of the membrane is developed. The model is a... more
The investigation of the hexane extract from aerial parts of Lychnophora pinaster provided, besides others substances, the E-isomer of lychnophoric acid, a sesquiterpene derivative previously isolated from L. affinis.
In presenting this thesis in partial fulfillment of the requirements for an advanced degree at the University of British Columbia, I agree that the Library shall make it freely available for reference and study. I further agree that... more
The aim of this study was to extract oil from sweet orange seeds and determine potential applications by investigating the physicochemical parameters of the oil. The seeds of Citrus sinesis were collected, washed and prepared for uses... more
We describe a general model to explore responsive adsorption processes in flexible porous materials. This model combines mean field formalism of the osmotic potential, classical density functional theory of adsorption in slit pore models... more
This study deals with onshore oilfield drilling fluid system to drill corrosion. Corrosion under static and dynamic conditions of the drilling fluid was evaluated. The effect of temperature and pressure on corrosion was examined.... more
TiO2 submicron fibers were prepared by atmospheric pressure plasma assisted calcination.  Low temperature plasma pre-treatment of Ti(Bu)/PVP fibers in ambient air was realized using Diffuse Coplanar Surface Barrier Discharge. ... more
Recently, an interest from both academia and industry has been moved toward ionic liquids due to their environmentally friendly characteristics as green alternative for traditional volatile organic solvents (VOCs). In addition, because of... more
The preparation of highly efficient and low-cost activated carbon from sawdust was achieved for the treatment of uranium-contaminated groundwater. The adsorption properties of the synthesized activated carbon, as well as their ability to... more
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