MX2020012204A - Inhibidores de kras g12c para tratar el cáncer. - Google Patents

Inhibidores de kras g12c para tratar el cáncer.

Info

Publication number
MX2020012204A
MX2020012204A MX2020012204A MX2020012204A MX2020012204A MX 2020012204 A MX2020012204 A MX 2020012204A MX 2020012204 A MX2020012204 A MX 2020012204A MX 2020012204 A MX2020012204 A MX 2020012204A MX 2020012204 A MX2020012204 A MX 2020012204A
Authority
MX
Mexico
Prior art keywords
inhibitors
kras
treat cancer
colorectal
compositions
Prior art date
Application number
MX2020012204A
Other languages
English (en)
Inventor
Victor J Cee
Brian Alan Lanman
Jian Chen
Nuria A Tamayo
Youngsook Shin
Longbin Liu
Ryan Paul Wurz
Hui-Ling Wang
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2020012204A publication Critical patent/MX2020012204A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

(VER FORMULA) En la presente se proporcionan inhibidores de KRAS G12C tales como composiciones de estos y métodos de utilización de estos. Estos inhibidores son útiles para tratar múltiples trastornos, incluido cáncer pancreático, colorrectal y de pulmón.
MX2020012204A 2018-06-11 2019-06-10 Inhibidores de kras g12c para tratar el cáncer. MX2020012204A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862683263P 2018-06-11 2018-06-11
PCT/US2019/036397 WO2019241157A1 (en) 2018-06-11 2019-06-10 Kras g12c inhibitors for treating cancer

Publications (1)

Publication Number Publication Date
MX2020012204A true MX2020012204A (es) 2021-03-31

Family

ID=67253966

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020012204A MX2020012204A (es) 2018-06-11 2019-06-10 Inhibidores de kras g12c para tratar el cáncer.

Country Status (8)

Country Link
US (2) US20190375749A1 (es)
EP (2) EP3802537A1 (es)
JP (2) JP7357644B2 (es)
AU (1) AU2019284472B2 (es)
CA (1) CA3099799A1 (es)
MA (1) MA52780A (es)
MX (1) MX2020012204A (es)
WO (1) WO2019241157A1 (es)

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MA52780A (fr) 2021-04-14
WO2019241157A1 (en) 2019-12-19
EP3802537A1 (en) 2021-04-14
US12583854B2 (en) 2026-03-24
US20220002298A1 (en) 2022-01-06
CA3099799A1 (en) 2019-12-19
JP7611978B2 (ja) 2025-01-10

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