JP2002543103A - Cosmetic and / or diet composition comprising a mixture of lycopene and olive leaf extract - Google Patents

Abstract

  (57) [Summary] The present invention relates to a cosmetic and / or diet composition. The composition comprises an active mixture of lycopene and olive leaf extract. The olive leaf extract solubilizes lycopene and combines the lipid regulating effect of the olive leaf extract with the cell preservation effect of lycopene. The present invention also relates to the use of the composition, a cosmetic treatment or dieting method using the composition and a method for producing the composition of the present invention.

Description

DETAILED DESCRIPTION OF THE INVENTION TECHNICAL FIELD OF THE INVENTION

 The present invention relates to a cosmetic and / or diet composition.

The invention also relates to the use of this composition for the preparation of cosmetics having anti-aging properties, and to diet properties, in particular blood pressure lowering-anticonvulsant properties, atherosclerosis preventing properties, antioxidation and It also relates to the use of orally ingestible formulations having anti-radical properties, collagen protection properties and cell aging process slowing properties.

Furthermore, the invention relates to a cosmetic and dieting method and to a method for producing the composition according to the invention.

[0003] In particular, the invention has application in the field of the manufacture of cosmetic and diet products, mainly for the manufacture of products based on plants.

[0004]

[Prior art]

 Certain physical properties of lycopene are already known.

[0005] In this regard, WO 97/47278 relates to compositions having bronze-promoting and sunscreen activity for oral or topical application and their cosmetic applications. This composition is a type of skin pigmentation regulating composition containing a carotenoid, and basically comprises the following two components: beta-carotene,
A component selected from the group consisting of beta alpha carotene and mixtures thereof, comprising at least one naturally occurring carotenoid also having provitamin activity;
A component corresponding to at least one naturally occurring carotenoid without provitamin activity, which is lycopene optionally selected from the group consisting of zeaxanthin, cryptoxanthin, lutein, and mixtures thereof, and optionally lycopene combined with other components ( The ratio between these components and lycopene is 0.95 / 1 to 1/50).

[0006] However, actual compositions are not entirely satisfactory.

First of all, lycopene is a very difficult substance to solubilize.

[0008] Therefore, its utilization is difficult and the compositions obtained in practice are not always homogeneous and stable.

[0009] It can be proved that physical properties other than those aimed at promoting sunburn and preventing sunburn are derived from lycopene.

[0010]

[Problems and Solutions to be Solved by the Invention]

Lycopene can also be utilized in combination with other components that allow for a synergistic effect.

It is an object of the present invention to utilize lycopene in combination with other substances, especially olive leaf extract and pure red wine extract.

The advantage of such a combination is that it achieves a good solubilization of lycopene and combines the two substance properties with the protective properties of red wine polyphenols.

[0013] To date, lycopene is regarded as a substance that is very difficult and even impossible to completely solubilize.

[0014] Applicants' research has established that sufficient solubilization of lycopene can be achieved by combining lycopene with olive leaf extract.

The present invention has an advantage that it has the properties of maintaining health by diet and anti-aging at the same time.

In this way, the same active ingredient can be used for internal use and external use.

Further, the present invention has an advantage that it can take various forms, such as a granular form which can be ingested orally, and a form of an oil which is topically applied externally.

[0018] It is likewise noted that the composition according to the invention can be produced from entirely natural ingredients, such as tomatoes, olive leaves, red wine and the like.

Other objects and advantages will become apparent in the following non-limiting description.

The cosmetic and / or diet composition of the present invention comprises an active mixture of lycopene and an olive leaf extract, the olive leaf extract solubilizes the lycopene, and the lipid regulating effect of the olive leaf extract is lycopene. Characterized in that it is associated with the cell preservation effect of

The present invention also relates to the use of a composition for the preparation of a cosmetic having anti-aging properties.

The present invention also relates to the use of a composition for the preparation of an orally ingestible formulation with dietary properties that avoids lipid excess and aging.

The cosmetic and dietary treatment methods of the present invention, excluding any therapeutic treatment, utilize an active mixture of olive leaf extract and lycopene both for external topical application and for oral administration. It is characterized by comprising.

The method for producing a composition according to the invention is characterized in that the active mixture comprises:-adding the tomato oleoresin little by little to the concentrated olive extract with stirring;-maintaining stirring to optimize the solubilization. 25% pure red wine extract in a 50% v / v water / alcohol mixture
m / m solution;-adding the obtained red wine solution to a solution of the tomato oleoresin and the olive leaf extract under low speed stirring.

[0025]

BEST MODE FOR CARRYING OUT THE INVENTION

 The composition of the present invention can be used in the embodiments described below.

The active mixture comprises one or more polyphenolic species having antioxidant properties.

The lycopene is derived from tomato extract.

The one or more polyphenolic species is obtained from red wine.

The composition of the present invention has a granular shape.

The composition of the present invention takes the form of an oil.

The composition of the present invention is formulated in the following weight ratio:-Lemon extract: 5-10%-Tomato oleoresin containing 6% lycopene: 5-10%-Olive extract: 5-10%-Pure red wine Extract: 1 to 5%-Broccoli: 1 to 5%-Citric acid: 1 to 3%-Sodium carbonate: 1 to 3%-Sweet orange essential oil: 1 to 3%-Excipient Maltitol: A sufficient amount. The active mixture of the composition comprises, in equal proportions by weight:-a tomato oleoresin;-a concentrated extract of olive leaves, 4 times more concentrated than the dry powder of olive leaves;-50% by volume of water and 50%. It is formed from a pure red wine extract, which is contained in a solution with 25% by volume of alcohol at a rate of 25%.

The composition according to the invention is formulated in the following weight ratios:-0.01 to 1% of said active mixture-30 to 50% of olive oil-10 to 55% of sweet almond oil-Wheat germ oil 1 to 20 %-Primrose oil 1-20%-borage oil 1-20%, and-ylang ylang essential oil 0.1-0.5%-geranium essential oil 0.1-0.5%-fragrance 0.3-1%-lemon Essential oils Essential oils such as 0.1-0.5%.

The composition according to the present invention can be used in the fields of beauty and diet.

The composition comprises an active mixture.

The active mixture comprises both lycopene and olive leaf extract.

Lycopene has antioxidant and antifree radical properties. Lycopene is obtained from tomato extract.

In fact, the tomato oleoresin contains lycopene.

The active mixture contains an olive leaf extract.

This extract has the effect of lowering cholesterol levels and preventing cardiovascular disease. Furthermore, it has blood pressure lowering ability and anticonvulsant ability, and prevents atherosclerosis.

The olive oil contained in the cosmetics is rich in polysaturated fatty acids having beneficial properties for maintaining skin health.

In order to produce the composition of the present invention, an extract obtained from olive leaf powder can be used.

Olive leaf extract has the very advantageous property of solubilizing lycopene.

In addition, the simultaneous use of lycopene and olive leaf extract combines complementary effects in terms of cell integrity and lipid regulation, respectively. Red wine extract can further enhance this connection.

Accordingly, a true synergistic effect is exhibited by the combination of the substances.

In a preferred embodiment, the active mixture also comprises one or more polyphenolic species provided that: total polyphenols: 92% (catechin equivalent); proanthocyanidol: at least 45%.

These polyphenolic species have very advantageous properties: anti-free radical properties, collagen protective properties and slowing of the cell senescence process.

This means providing a “pool” of polyphenols.

This “pool” also avoids free radicals and will have an effect, especially in the prevention of connective tissue aging and cancer.

[0049] The red wine extract contains about 46% proanthocyanidol.

In another embodiment, an extract of grape seed, which itself contains 50% or more of proanthocyanidins, can be utilized.

Hereinafter, a preferred embodiment of the active mixture used in the composition according to the present invention expressed by weight ratio will be described.

In this connection, a mixture is prepared using tomato oleoresin, olive concentrate extract and red wine pure extract in equal proportions by weight.

The olive concentrate extract is obtained from olive leaf powder and concentrated 4 times.

Further, the red wine extract is used in a 50% by volume solution of water and alcohol.
It is a pure extract prepared to be 5%.

One of the advantages of the composition of the present invention is its use flexibility, which can be used in an ingestible form or an external use form.

For example, compositions can be formed which are in particular in the form of granules, even oils.

In order to achieve an orally ingestible composition such as granules, the following formulas by weight unit: Lemon extract: 5-10%; Lemon constitutes an excellent binder and a valuable aromatic compound I do. -Tomato oleoresin containing 6% lycopene: 5-10%: Tomatoes actually contain lycopene and are the main ingredient of a completely natural product, especially used in Mediterranean diets. Olive extract: 5-10%; olive extract is likewise derived from the Mediterranean diet. -Red wine pure extract: 1-5%; if pure red wine extract is involved, polyphenols will likewise be included in the range of Mediterranean diet products. -Broccoli: 1-5%; Broccoli has the advantage of detoxification properties. -Citric acid: 1-3%-sodium carbonate 1-3%; sweet orange essential oil 1-3%-flavoring agent: 0.3-1%-excipient: sufficient (Qsp) maltitol

Particularly in the field of application in the form of topical oils, the compositions are formulated in the following proportions by weight: lycopene, olive leaves and red wine extract 0.01% to 1% sweet almond oil, olive oil And vegetable oils including wheat germ oil, primrose oil and borage oil-essential oils such as ylang-ylang 0.1-0.5% geranium 0.1-0.5% lemon 0.1-0.5%.

Flavors can also be added at a level of 0.3-1%.

The contribution of the essential oil is important in the composition according to the invention.

For example, geranium essential oil is a tonic and a skin regenerative substance.

Geranium essential oils exhibit very rich olfactory effects and other skin properties that are noteworthy in cosmetics.

Geranium essential oil is rich in citronellol and geraniol.

[0064] Ylang-Ylang essential oil also has a tonic regenerating effect on the skin.

When ylang-ylang essential oil is used together with geranium essential oil, it shows particularly high activity and shows excellent capillary vein tonicity.

Lemon essential oil prevents facial wrinkles and keeps hands smooth.

Furthermore, the composition is given a beneficial lemon-like light aroma.

The present invention also relates to the use of the composition according to the invention.

The composition of the present invention in the form of an oil or a cream according to the above-mentioned formulation using vegetable oil and essential oil can be used for preparing a cosmetic formulation having anti-aging properties.

At this time, topical application of oil or cream to the skin is essential.

The present invention also relates to the use of the composition according to the present invention in an ingestible form.

This form may be in the form of granules, or any form that can be sucked, chewed, swallowed, drunk or dissolved for oral ingestion.

The composition is used for preparing a formulation having dietary properties such as blood pressure lowering, anticonvulsant, and prevention of atherosclerosis.

It will be appreciated that the compositions of the present invention are available in internal and external forms.

[0075] These two uses can also be combined.

Thus, the present invention relates to cosmetic and dietary treatment methods, except for any therapeutic treatment.

This method consists in simultaneously using an active mixture comprising lycopene and olive leaf extract, and preferably red wine extract, for external and internal use.

The complementarity of these two uses is particularly advantageous.

Hereinafter, a method for producing the composition according to the present invention will be described.

As a matter of course, the embodiments described below do not limit the method for producing the composition of the present invention.

The method described below has the advantage that lycopene can be effectively solubilized in olive leaf extract.

The active mixture of the composition according to the invention is produced by the following steps: To the olive concentrate extract, the tomato oleoresin is added in small portions under stirring.
The tomato oleoresin contains lycopene. The gradual dissolution of the two components becomes possible by adding the olive extract little by little under stirring. -Maintain stirring to optimize solubilization. The stirring time may be about one hour. -Prepare a solution of pure red wine extract in parallel with stirring. Then, lycopene and olive leaf extract are added to obtain a clear solution. This last addition is preferably performed under low speed stirring to obtain a completely homogeneous final composition.

As explained above, the present invention has the advantage of using the components of a completely natural product (red wine extract, tomato and olive leaf extract) used in a Mediterranean diet.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI theme coat ゛ (Reference) A61K 7/00 A61K 7/00 BC L 7/48 7/48 31/01 31/01 47/04 47/04 47/10 47/10 47/12 47/12 47/26 47/26 47/44 47/44 A61P 3/06 A61P 3/06 9/10 101 9/10 101 9/12 9/12 17 / 16 17/16 21/02 21/02 43/00 105 43/00 105 (81) Designated countries EP (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE), OA (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG), AP (GH) , GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW), EA (AM, AZ, BY, K) , KZ, MD, RU, TJ, TM), AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE , DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL , TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW. Mediterranean de Bourbet d'Anva Zion et de Marc (72) Inventor Zaannini, Gareitano F-06000 Nice-Leu Massena 24 Cabinet-Otier-office Mediterranean-du-Bourbe-d'Ambancion de Marc F-term (reference) 4B018 LE02 LE05 MD01 MD07 MD09 MD14 MD52 MD53 MD61 MD91 ME01 ME06 ME08 ME10 MF01 MF08 4C076 BB01 BB31 CC11 CC18 CC21 CC40 DD25 DD43 DD67 EE53 EE57 GG46 4C083 AA111 AA121 AB051 AB311 AC011 AC101 AC131 AC301 AC471 BB41 CC05 CC06 DD30 DD31 AB56 AB15 AB56 AB13 AB53 AB53 AB31C48 BA06 MA08 MA52 MA63 ZA36 ZA42 ZA45 ZA70 ZA89 ZA94 ZB21 ZC33 4C206 AA01 AA02 BA02 MA03 MA05 MA12 MA83 NA02 NA14 ZA36 ZA42 ZA45 ZA70 ZA89 ZA94 ZB21 ZC33

Claims (13)

[Claims] Claims: 1. A cosmetic and / or diet composition comprising an active mixture of lycopene and olive leaf extract, wherein the olive leaf extract solubilizes lycopene, A composition wherein the lipid regulating effect of olive leaf extract is combined with the cell preserving effect of lycopene. 2. The cosmetic and / or diet composition according to claim 1, wherein the active mixture comprises one or more polyphenol species having antioxidant properties. 3. The cosmetic and / or diet composition according to claim 1, wherein the lycopene is derived from a tomato extract. 4. The cosmetic and / or diet composition according to claim 2, wherein the one or more polyphenol species are obtained from red wine. 5. The cosmetic and / or diet composition according to claim 1, wherein the composition is in the form of granules. 6. The cosmetic and / or diet composition according to claim 1, wherein the composition is in the form of an oil. 7. The cosmetic and / or diet composition according to claim 5, wherein the composition is formulated by the following weight ratio:-Lemon extract: 5-10%-Tomato oleoresin containing 6% lycopene : 5-10%-Olive extract: 5-10%-Pure red wine extract: 1-5%-Broccoli: 1-5%-Citric acid: 1-3%-Sodium carbonate: 1-3%-Sweet orange essential oil: 1-3%-excipient maltitol: a composition characterized by a sufficient amount. 8. The cosmetic and / or diet composition according to claim 3, wherein the active mixture is 4 times concentrated from equal weight ratios of:-tomato oleoresin,-dry powder of olive leaves. Concentrated extract of olive leaves and
A composition consisting of: a pure red wine extract comprised of 25% by volume in a solution of 50% by volume of water and 50% by volume of alcohol. 9. The cosmetic and / or diet composition according to claim 6, wherein the composition has the following weight ratio:-the active mixture 0.01-1%-olive oil 30-50%. -Sweet almond oil 10-55%-wheat germ oil 1-20%-primrose oil 1-20%-borage oil 1-20%,-ylang ylang essential oil 0.1-0.5%-geranium essential oil 0.1 -0.5%-essential oil of lemon 0.1-0.5%-essential oil such as fragrance 0.3-1%. 10. Use of a composition according to claim 6, 8 or 9 for preparing a cosmetic having anti-aging properties. 11. Use of a composition according to claim 5 or 7 for preparing an ingestible formulation having dietary properties that avoids lipid excess and aging. 12. A cosmetic or dietary treatment method, excluding any therapeutic treatment, characterized in that an active mixture of olive leaf extract and lycopene is used both by external topical application and by oral ingestion. And the treatment method. 13. The method for producing a composition according to claim 8, wherein the active mixture comprises:-adding the tomato oleoresin little by little to the olive concentrated extract while stirring;-optimizing the solubilization. To maintain stirring, 25% pure red wine extract in a 50% v / v water / alcohol mixture
preparing a m / m solution; adding the resulting red wine solution to a solution of the tomato oleoresin and the olive leaf extract under low-speed stirring to produce a composition.