Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Farmaka International Journal of Integrated Health Sciences Althea Medical Journal Jurnal Kesehatan Andalas Indonesian Journal of Biotechnology
Afiat Berbudi
Fakultas Farmasi Universitas Padjadjaran
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
REVIEW: AKTIVITAS IMMUNOMODULATOR TANAMAN SAMBILOTO (Andrographis paniculata Nees) Maulana Yusuf Alkandahri; Anas Subarnas; Afiat Berbudi
Farmaka Vol 16, No 3 (2018): Farmaka (September)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (194.811 KB) | DOI: 10.24198/jf.v16i3.14237

Abstract

Artikel ini mengulas tentang aktivitas immunomodulator tanaman sambiloto (Andrographis paniculata Nees.) yang digunakan sebagai terapi alternatif dalam meningkatkan sistem imunitas tubuh. Sambiloto (Andrographis paniculata Nees) merupakan tanaman asli Indonesia yang banyak diteliti saat ini, terutama aktivitas immunomodulator yang dimilikinya. Aktivitas immunomodulator dari sambiloto ini disebabkan karena adanya kandungan senyawa aktif berupa deoxyandrographolide, andrographolide, 14-deoxy-11, neoandrographolide, 12- didehydroandrographolide, homoandrographolide, diterpenoid dan flavonoid yang terkandung di dalam sambiloto. Sebagai agen immunomodulator, sambiloto dapat digunakan sebagai immunostimulator yang meningkatkan respon imun saat kekebalan tubuh menurun, dan juga bisa menjadi imunosupresor yang dapat menurunkan respon kekebalan tubuh saat sistem kekebalan tubuh meningkat melebihi kondisi tubuh normal. Selain itu, sebagai immunomodulator, sambiloto juga mampu menormalkan kondisi tubuh meskipun terjadi infeksi.Kata kunci : Sambiloto, Andrographis paniculata Nees., Immunomodulator, Andrographolide
Performance of CO1 and ITS2 nested PCR in molecular identification of ordinary scabies (Sarcoptes scabiei var. hominis) Gita Dwi Prasasty; Miftahurrizqiyah Miftahurrizqiyah; Chairil Anwar; Dwi Handayani; Dalilah Dalilah; Ahmad Ghiffari; Inda Astri Aryani; Nunuk Dyah Retno Lastuti; Afiat Berbudi
Indonesian Journal of Biotechnology Vol 26, No 4 (2021)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijbiotech.64472

Abstract

Scabies is a global disease with a high prevalence, causing morbidity and even mortality, especially in poor and developing countries. However, it is often misdiagnosed due to varied and unspecified lesions. The gold standard technique for diagnosis is a microscopic examination, which requires experienced experts in finding mites, mainly in ordinary scabies. CO1 and ITS2 genes have been widely used in molecular identification to detect Sarcoptes scabiei and its variants. This study aimed to determine and compare the sensitivity and specificity of CO1 and ITS2 S. scabiei genes to the microscopic examination of scabies skin scrapings. The skin scrapings of 52 subjects with scabies diagnosed by anamnesis, physical examination, and dermoscopic examination were examined under a microscope and analyzed by nested PCR. The diagnostic test result showed that the sensitivity of nested PCR of both CO1 and ITS2 genes to micro‐ scope examination was 100%. However, the specificity of both CO1 and ITS2 nested PCR was poor (24% and 0%). Hence, CO1 and ITS2 nested PCR could be more suitable for screening ordinary scabies in humans than the microscopic examination.
Characteristics and Complications of Tuberculous Meningitis Patients with Hydrochepalus Undergone Fluid Diversion in Dr. Hasan Sadikin General Hospital, Bandung Adriani Lawrencia Novalia; Afiat Berbudi; Ahmad Faried; Heda Melinda Nataprawira
International Journal of Integrated Health Sciences Vol 6, No 1 (2018)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.71 KB) | DOI: 10.15850/ijihs.v6n1.1048

Abstract

Objective: To describe the clinical characteristics and complications observed in tuberculous meningitis (TBM) patients with hydrocephalus who had undergone fluid diversion management.Methods: This was a cross-sectional descriptive observational study involving 28 TBM patients with hydrocephalus aged 0–5 years who had undergone ventriculoperitoneal shunt or extraventricular drainage in the period of July 2011 to July 2016 in Dr. Hasan Sadikin General Hospital, Bandung. Age, gender, head circumferences, nutritional status, and classical characteristics such as sunset eye, frontal bossing, cracked pot sign, venectation as well as complications such as infection, phlebitis, and exposed shunt documented in the hospital medical records were analyzed.Result: The study discovered that infant group was predominant (21/28). Some of the patients had macrocephalus (7/28) and 18 had good nutrition status (18/28). There were 4 patients with frontal bossing characteristics (4/28) and almost none was found with others classic hydrocephalus characteristics. This study found no complication such as infection, phlebitis, and exposed shunt in TBM patients with hydrocephalus who had undergone fluid diversion therapy in Dr. Hasan Sadikin General Hospital, Bandung.Conclusion: One of the most dominan characteristics of TBM patients with hydrocephalus is frontal bossing. Tuberculous meningitis patients with hydrocephalus in our center did not show any fluid diversion-related complications such as infection, phlebitis, or exposed shunt.Keywords: Tuberculous meningitis, hydrocephalus, fluid diversion DOI: 10.15850/ijihs.v6n1.1048
Determinant of Hypertension among Adults in West Java, Indonesia: Analysis of National Basic Health Research Data 2018 Karlen, Jannatin; Berbudi, Afiat; Wahyudi, Kurnia
Althea Medical Journal Vol 10, No 4 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n4.2826

Abstract

Background: Hypertension is a serious health problem worldwide. Many studies on the determinants of hypertension have been done, however studies in West Java are still very minimal. This study aimed to determine the risk factors for hypertension among adults in West Java, Indonesia.Methods: This study used a cross-sectional method with a quantitative approach using secondary data from the National Basic Health Research 2018. The final number of individuals sampled was 46,186 people. Data analysis was performed using simple logistic regression and multiple logistic regression methods.Results: The mean age of the sample was 42.97 years (SD=15.37), and females were the predominant (52.95%). The majority of samples consumed sweet beverages (31.06%) and salty foods more than once a day (29.22%), did not smoke (59.17%), had a normal body mass index (BMI) (53.78 %), and had experienced gum disease and dental problems in the last year (56.75 %). Physical activity in metabolic equivalent task (MET) minute was 5,917.79. There was a significant positive association between age and hypertension, with an odds ratio (OR) of 1.06 and a 95% confidence interval (CI) of 1.05–1.06. Furthermore, the analysis found a significant negative correlation between physical activity and hypertension, with an OR of 0.999 and a 95% CI of 0.9999874–0.9999962.Conclusions: Hypertension is significantly associated with age, whereas physical exercise is negatively associated. Priority should be given to elderly individuals and people with a high BMI for interventions such as routine blood pressure monitoring and education.
Korelasi Status Nutrisi dengan Tingkat Kadar Hemoglobin Darah pada Anak Usia Sekolah Dasar Markidam di Desa Cilame Kabupaten Bandung Oktorina, Lenny; Hakim, Fadhli Dharmansyach; Buntoro, Josep Dharmadi; Berbudi, Afiat; Ewangga, Bayu
Andalas Journal of Health Vol. 12 No. 1 (2023): Online March 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v12i1.2154

Abstract

Malnutrition has many adverse effects, including a decrease in hemoglobin levels, or known as anemia. Malnutrition caused by nutritional deficiencies can affect the decrease in hemoglobin levels or anemia. Objective: To determined the correlation between nutritional status and hemoglobin levels in Markidam elementary school-age children in Cilame Village Methods: This cross-sectional study uses primary data from research subjects who have agreed. The number of subject research that has been taken was 143 respondents. Anthropometric examinations using weight scales and microtoise were then carried out in a plotting process to determine the nutritional status of respondents. The hemoglobin level was used as a rapid diagnostic test tool with the Easytouch brand type GCHB. Spearman test to find out the results of this research hypothesis. Results:  Hemoglobin levels did not have a significant correlation with nutritional status. This could be seen from the significance value (p-value) of 0,172, where this value is greater than 0,05. Conclusion: There is no correlation between nutritional status and hemoglobin level at the age of elementary school children.Keywords: anemia, hemoglobin, nutritional status
Co-Authors Adriani Lawrencia Novalia Ahmad Faried Ahmad Ghiffari Anas Subarnas Buntoro, Josep Dharmadi Chairil Anwar Cintami Putri, Almahitta Dwi Handayani Ewangga, Bayu Gita Dwi Prasasty Hakim, Fadhli Dharmansyach Heda Melinda Nataprawira Ifham Hanif, Muhammad Inda Astri Aryani Karlen, Jannatin Kurnia Wahyudi, Kurnia Maulana Yusuf Alkandahri Miftahurrizqiyah Miftahurrizqiyah Nunuk Dyah Retno Lastuti Oktorina, Lenny