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All Journal Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Jurnal Sains Student Research
Dwi Krihariyani
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Uji Efektivitas Daya Hambat Ekstrak dan Perasan Lidah Buaya (Aloe barbadensis Miller) pada Bakteri Staphylococcus Aureus dengan Metode Difusi Farah Adilah Ambar Sari; Suliati Suliati; Syamsul Arifin; Dwi Krihariyani
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 2 No. 4 (2024): Oktober : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v2i4.4307

Abstract

Aloe vera is a plant that is rich in minerals, vitamins, and antibacterial properties. A study to analyze the antibacterial effectiveness of aloe vera in inhibiting the growth of Staphylococcus aureus bacteria isolated from acne pus. This study was an experimental laboratory study using the disc diffusion method, located at the Bacteriology Laboratory, Department of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya, from February to May 2024. There were 6 sample treatments with 4 replications, 4 treatments of extract and juice concentration variations, namely concentrations of 70%, 80%, 90%, 100%, positive control using penicillin antibiotics, and negative control using clean distilled water. The results of this study show that at aloe vera extract concentrations of 70%, 80%, 90%, and 100%, the average diameter of the inhibition zone was 9 mm, 10 mm, 11 mm, and 12 mm, respectively, while in aloe vera juice, these concentrations did not form an inhibition zone. So it was concluded that aloe vera extract is more effective than aloe vera juice, the most successful test material to slow the growth of Staphylococcus aureus bacteria in this study was aloe vera extract with a concentration of 100%. This study also conducted qualitative phytochemical testing on aloe vera extract which has antibacterial compounds, namely saponins, tannins, flavonoids, and terpenoids. The results of the study on the effectiveness of the inhibitory power of aloe vera extract and juice against Staphylococcus aureus bacteria using the disc diffusion method were analyzed using quantitative descriptive and presented in tabulation form in the form of the diameter of the inhibition zone formed.
Korelasi Kadar Serum Iron Dengan Hemoglobin Pada Pasien Gagal Ginjal Kronik Level V Di RSUD Dr. Harjono S Ponorogo Yulia Hermawati; Dwi Krihariyani; Syamsul Arifin; Wisnu Istanto
JOURNAL SAINS STUDENT RESEARCH Vol. 3 No. 4 (2025): Jurnal Sains Student Research (JSSR) Agustus
Publisher : CV. KAMPUS AKADEMIK PUBLISING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61722/jssr.v3i4.5975

Abstract

Chronic Kidney Disease (CKD) is not merely a condition of permanently decreased renal function, but it also significantly impacts patients’ quality of life. One of the major complications is anemia. Iron deficiency is a primary contributor to anemia in CKD patients, often resulting from reduced erythropoietin production, blood loss during hemodialysis, and inadequate iron intake. This study aims to determine the relationship between serum iron levels (iron in the blood) and hemoglobin levels in stage V chronic kidney disease (CKD) patients undergoing regular hemodialysis at Dr. Harjono S. Ponorogo Regional Hospital, using a quantitative descriptive-analytic approach based on secondary data from the hospital's Laboratory Information System (LIS). A total of 24 CKD patients undergoing hemodialysis twice a week during the period of July to December 2024 were included as research subjects. The results showed that all patients experienced anemia. Although most patients had serum iron levels within the normal range, hemoglobin levels remained low. Statistical analysis revealed a moderate correlation between serum iron and hemoglobin levels, with a statistically significant p-value (p < 0.05) in both examinations. A moderate and statistically significant correlation was found between serum iron and hemoglobin levels in stage V CKD patients, indicating that monitoring iron status is important in the management of anemia in chronic kidney disease.
Co-Authors Farah Adilah Ambar Sari Suliati Suliati Syamsul Arifin Wisnu Istanto Yulia Hermawati