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Pengolahan Jamu Tradisional sebagai Minuman Peningkat Imunitas Tubuh Sama’ Iradat Tito; Muhammad Ma’ruf; Arina Roikhana; Lailatul Maghfirah; Sulis Setiawati; Zuhrotul Chumairoh; Nur Mufida; Durrotul Hasanah
Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Vol 2, No 2 (2021): Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M)
Publisher : Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jp2m.v2i2.13244

Abstract

Jamu merupakan obat tradisonal dengan bahan dasarnya berasal dari alam dengan pemberian dari warisan budaya secara turun-temurun dari generasi ke generasi. Dimasa pandemi Covid-19 ini, masyarakat disarankan untuk banyak mengonsumsi jamu dengan tujuan untuk meningkatkan imunitas tubuh selama pandemi ini. Salah satu upaya yang dapat dilakukan yakni melakukan sosialisasi kepada Ibu PKK serta perangkat Desa Srimulyo tentang pengolahan jamu tradisonal yang mempunyai potensi sebagai minuman peningkat imunitas tubuh. Metode yang digunakan yaitu metode pendekatan langsung, cerama dan praktek. Metode pendekatan yang dilakukan untuk mengetahui permasalahan yang ada di Desa Srimulyo. Metode ceramah dilakukan memberikan informasi tentang manfaat dari jamu tradisional sebagai minuman meningkatkan imunitas tubuh. Metode praktek dilakukan untuk memberikan pelatihan pengolahan jamu tradisional yang baik dan benar. Hasil yang didapat melalui kuisioner uji organoleptik didapat nilai rata-rata rasa olahan jamu tradisional 3.60, nilai rata-rata aroma olahan jamu tradisional 3.85, nilai rata-rata warna olahan jamu tradisional 3.75, dan nilai rata-rata kesukaan olahan  jamu tradisional 3.70.
Analysis of the theory of planned behavior on the use of halal-labeled cosmetics for students at the University of Islamic Malang Muhammad Ma'ruf; Nina Salamah
Journal of Halal Science and Research Vol. 4 No. 2 (2023): September
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v4i2.7122

Abstract

The practice of using halal cosmetics involves the intentional involvement of individuals, groups, or organizations in acquiring and using cosmetics that have obtained a halal certification. The behavior of individuals is subject to influence by multiple factors, including attitudes, subjective norms, behavioral control, and intention to use. These factors are motivated by the desires and needs of the individual. This study examines the influence of attitudes, subjective norms, behavioral control, and usage intentions on adopting halal-labeled cosmetics among college students. This research investigates the impact of attitudes, subjective norms, behavioral management, and usage intentions on adopting cosmetics labeled as "halal" among college students. The study employs online surveys as the primary method for data collection. The research utilized a purposive sampling methodology to select a sample size of 110 participants. The present study utilizes a data analysis technique that involves applying multiple regression analysis using the SPSS 25.0 software. The results of this study indicate that the variables of attitude, behavioral control, and intention to use have a statistically significant impact on the utilization of halal-certified cosmetic products. On the other hand, the influence of subjective norms on the utilization of halal decorative goods among students enrolled in the Faculty of Mathematics and Natural Sciences at the University of Islamic Malang is determined to have no significant statistical effect. Keywords: Halal, Cosmetics, Students, Theory of Planned Behavior.
Phytochemical Screening Analysis and Determination of Total Flavonoids and Total Phenolics Content of Ethanol Extract of Sungkai Leaf (Penorema canescens Jack) from Samarinda City Muhammad Ma'ruf; Moch. Saiful Bachri; Laela Hayu Nurani
Jurnal Mandala Pharmacon Indonesia Vol. 9 No. 2 (2023): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v9i2.360

Abstract

Sungkai is a plant that contains compounds such as flavonoids, tannins, phenolics, saponins, steroids, and terpenoids, which have the potential to develop native Indonesian herbal medicines to treat the prevention and treatment of various diseases. This research aimed to analyze phytochemical screening and the total flavonoid and phenolic content in sungkai leaves originating from Samarinda City. This research method was carried out by extracting sungkai leaves with 96% ethanol and evaporating them with a vacuum rotary evaporator. Sungkai leaf extract was analyzed for phytochemical screening using the tube method with color testing from various reagents and total phenolic and flavonoid content testing using the colorimetric method using a UV-Vis spectrophotometer. The results of the phytochemical screening showed that the ethanol extract of sungkai leaves from Samarinda City was positive for containing flavonoids, saponins, alkaloids, phenolics, and steroids. The results of determining the flavonoid and phenolic content of sungkai leaf ethanol extract were 18,210 ± 0.271 mg QE/g sample and 33,666 ± 1.052 mg GAE/g sample.
The Hepatoprotective Effect of Moringa oleifera Leaves on Male Wistar Rat Induced Streptozotocin-Nicotinamide Bachri, Moch Saiful; Nurani, Laela Hayu; Edityaningrum, Citra Ariani; Ma'ruf, Muhammad; Sulistyorini, Dwi Agustin; Amelia, Rizki; Hidayati, Sholihatil; Sulistyawati, Rini; Guntarti, Any
Majalah Obat Tradisional Vol 29, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.90806

Abstract

Diabetes mellitus is a disease characterized by uncontrolled increases in blood sugar levels, which can cause complications in the liver. Disorder liver disease can be seen from the increasing SGOT, SGPT activity, and the number of necrosis cells in the liver. Moringa leaves contain the flavonoid quercetin with antidiabetic and antioxidant activity. This research aimed to determine the effect of administering the ethyl acetate fraction of Moringa leaves on SGOT activity, SGPT, and liver histopathology in rat induced by streptozotocin and nicotinamide. Moringa leaves macerated with 80% ethanol and fractionated with ethyl acetate were used. The research subjects were 30 rats divided into six groups. The rats were induced with streptozotocin at a dose of 65 mg/kgBW and nicotinamide 100 mg/kgBW for five days, then treated for ten days. Serum SGOT and SGPT activity were measured using a Microlab 300 Semi-Automated at a wavelength of 340 nm. Histopathological observations were carried out when the rats were dislocated, their livers were taken, and then preparations were made using Hematoxylin Eosin (HE) staining. Data were analyzed using the SPSS One Way ANOVA method, followed by the Tukey test with a confidence level of 95%. The results of the study showed that administration of Ethyl Acetate Fraction of Moringa oleifera (EA-MO) could reduce the levels of SGOT, SGPT, and the number of liver necrosis cells in rats induced by streptozotocin and nicotinamide.
Jatropha curcas L. Leaf Extract Effects on Blood Pressure and Lipid Levels in Hypertensive Rats with High-Fat Diet Moch. Saiful Bachri; Wiki Yuli Anita; Putri Dwi Lestari; Desi Eko Wulansari; Dwi Retno Nengtyas; Muhammad Ma'ruf; Sapto Yuliani; Wahyu Widyaningsih; Laela Hayu Nurani; Daru Estiningsih; Vivi Sofia
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 1 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i12024.61-70

Abstract

Background: One of the main risk factors for cardiovascular diseases such as coronary atherosclerotic heart disease (CAHD) is dyslipidaemia or high levels of low-density lipoprotein (LDL) and triglycerides (TG) and low levels of high-density lipoprotein (HDL). Hypertension is also a cause of cardiovascular disease. One potential plant to lower LDL levels and blood pressure is Jatropha curcas, which is known to contain saponins, polyphenols, and flavonoids. Objective: The purpose of this study was to determine the effect of the ethanol extract of Jatropha curcas leaves (EEJCL) on blood pressure, LDL levels, and HDL levels in hypertensive rats given a high-fat diet. Methods: This study is an experimental study with a pretest-posttest control group design on male Wistar strain rats. Rats were divided into seven groups, namely the normal group, control group (induced with NaCl and given a high-fat diet), Captopril group, Simvastatin group, and EEJCL groups given doses of 1.8, 2.7, and 4.05 g/kg BW. The data obtained were analysed using the One-Sample Kolmogorov-Smirnov Test, Homogeneity of Variance, One-Way ANOVA, and Tukey Test. Results: The results showed that the administration of EEJCL could significantly lower LDL levels and blood pressure and increase HDL levels (p < 0.05) at doses of 1.8, 2.7, and 4.05 g/kg BW, and the dose of 4.05 g/KgBW was the most optimal dose. Conclusion: EEJCL has a potential for development in the treatment of hypertension and dyslipidaemia.
PROGRAM KEWIRAUSAHAAN BERBASIS TEKNOLOGI DAN LINGKUNGAN PADA KOMPLEK PERUMAHAN BARU DENGAN PENGOLAHAN PUPUK ORGANIK Agus Suryono; Imam Hanafi; Riyanto Riyanto; Sama' Iradat Tito; Hamdani Dwi Prasetyo; Muhammad Ma’ruf; Ghomamul Karim
Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024 Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) 2021
Publisher : Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024

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Abstract

Perumahan Griya Tama Pakis merupakan salah satu perumahan yang terletak di Desa Pakisjajar, Kecamatan Pakis Kabupaten Malang. Perumahan ini dikelola langsung oleh PT. Griya Karya Tama dan menjadi perumahan baru didaerah tersebut Dengan itu, perumahan baru akan menghasilkan permasalahan lingkungan yang cukup kompleks terhadap permasalah sampah yang berasal dari rumah tangga maupun daun-daun dari tumbuhan yang terdapat di setiap rumah ini. Salah satu cara untuk mengatasi permasalahan lingkungan yakni dengan melakukan pengolahan sampah tersebut menjadi pupuk organik. Metode yang digunakan yaitu metode pendekatan langsung, ceramah dan praktek. Metode pendekatan yang dilakukan untuk mengetahui permasalahan yang ada di Perumahan Griya Tama Pakis. Metode ceramah dilakukan memberikan informasi tentang manfaat dari pupuk organik. Metode praktek dilakukan untuk memberikan pelatihan pengolahan pupuk organik yang baik dan benar. Hasil yang didapat melalui kuisioner uji organoleptik didapat 13 dari 20 panelis menyatakan sangat suka terhadap tekstur dari pupuk organik dengan persentase (65%), kemudian 12 dari 20 panelis menyatakan sangat suka terhadap aroma dari pupuk organik dengan persentase (60%), dan 12 dari 20 panelis menyatakan sangat suka terhadap warna dari pupuk organik dengan persentase (60%)
UPAYA PENINGKATAN PERILAKU HIDUP BERSIH DAN SEHAT (PHBS) DI ERA PANDEMI COVID-19 KEPADA MASYARAKAT DESA SRIMULYO MELALUI MEDIA POSTER Sama' Iradat Tito; Muhammad Ma’ruf; Durrotul Hasanah; Arina Roikhana; Lailatul Maghfirah; Nur Mufida; Sulis Setiawati; Zuhrotul Chumairoh
Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024 Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) 2021
Publisher : Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024

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Abstract

Corona virus adalah suatu kelompok virus yang dapat menyebabkan penyakit saluran pernafasan pada manusia mulai dari batuk pilek hingga yang lebih serius seperti Middle East Respiratory Syndrome (MERS) dan Severe Acute Respiratory Syndrome (SARS). Wabah virus covid-19 telah menyebar ke berbagai negara di dunia dengan waktu yang sangat singkat, salah satunya adalah Indonesia. Program Perilaku hidup bersih dan sehat (PHBS) adalah program yang pada dasarnya bertujuan untuk membuat masyarakat meninggalkan pola hidup tidak sehat kehidup yang lebih sehat. Metode yang dilakukan dalam kegiatan ini yaitu metode ceramah, metode diskusi dan metode praktik. Pelaksanaan kegiatan pengabdian dalam program Kandidat Sarjana Mengabdi (KSM-Tematik) ini dilaksanakan mulai 2 Agustus – 14 September 2021. Tempat pelaksanaan kegiatan Kandidat Sarjana Mengabdi (KSM-Tematik) di Desa Srimulyo, Kecamatan Dampit, Kabupaten Malang. Kegiatan sosialisasi pencegahan penyebaran penyakit Covid-19 dengan sosialisasi melalui poster dan pembagian masker. Kegiatan ini dilakukan dengan bersosialisasi kepada masyarakat Desa Srimulyo dengan cara mempresentasikan poster, yaitu poster pencegahan Covid-19 dengan 5M & perilaku hidup bersih dan sehat (PHBS) melalui media poster. Kegiatan ini juga memberikan kuisioner kepada masyarakat yang diberikan saat sebelum dan sesudah diakannya sosialisasi penyuluhan ini. Hasil kuisioner sebelum penyuluhan tentang perilaku hidup bersih dan sehat (PHBS) dengan pengetahuan yang kurang sebanyak 10 orang (40%), pengetahuan yang cukup sebanyak 9 orang (36%), dan yang memiliki pengetahuan yang baik sebanyak 6 orang (24%).  Hasil kuisioner sesudah penyuluhan tentang perilaku hidup bersih dan sehat (PHBS) dengan pengetahuan yang kurang sebanyak 6 orang (24%), pengetahuan yang cukup sebanyak 7 orang (28%), dan yang memiliki pengetahuan yang baik sebanyak 12 orang (48%). Dengan hasil ini, masyarakat telah mengetahui pencegahan Covid-19 dengan 5M & perilaku hidup bersih dan sehat (PHBS) di lingkungan sekitar rumah
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER CLAY KOMBINASI EKTRAK ETANOL DAUN BAWANG DAYAK DAN KULIT JERUK SIAM Musiam, Siska; Ma'ruf, Muhammad; Kumalasari, Eka
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i3.2298

Abstract

Clay masks are a popular cosmetic due to their ability to rejuvenate the skin and detoxify the face. Clay masks can be made by adding dayak onion leaves and Siamese banjar orange peel, known to be rich in natural antioxidants containing various complex secondary metabolites. The aim of this research is to formulate and evaluate a clay mask preparation made from a combination of ethanol extracts of dayak onion leaves and Siamese banjar orange peel. The samples were extracted using the maceration method with 70% ethanol as a solvent. The ethanol extracts were then formulated into clay masks using kaolin as the base material, with ratios of 1:1, 2:1, and 1:2. The organoleptic evaluation showed no changes in color, odor, or texture of the masks during storage. All formulations were homogeneous with an average pH ranging from 5.19 to 5.97. The viscosity test results ranged from 29.14 to 37.05 Pa’s, the average spreadability was 27.12-38.90 mm, and the drying time ranged from 15.21 to 17.58 minutes. It can be concluded that the ethanol extract combination of dayak onion leaves and Siamese banjar orange peel can be formulated into a stable clay mask and all formulations meet the required physical evaluation.
MEKANISME KO-KEMOTERAPI EKSTRAK ROSELLA (Hibiscus sabdariffa. L) DENGAN DOXORUBICIN PADA SEL KANKER SERVIKS (HeLa) SECARA IN VITRO Daud, Intan; Hayu Nurani, Laela; Bachri, Moch. Saiful; Ariani Edityaningrum, Citra; Ma’ruf, Muhammad
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 2 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.2158

Abstract

Cervical cancer caused by exposure to Human Papilloma Virus (HPV) through sexual intercourse can be treated with Doxorubicin. Doxorubicin shows side effects so it needs to be combined with co-chemotherapy. Rosella (Hibiscus sabdariffa L.) The main content of anthocyanins is cytotoxic to HeLa cells.  The purpose of this study was to find co-chemotherapy combination of Doxorubicin and Rosella extract with apoptosis mechanism and Rosella antiproliferation.  The research method starts from the maceration process of Rosella petals using 96% ethanol. Cytotoxic test method, antiproliferation test, apoptosis, and combination test with MTT method using HeLa cells. The result of cytotoxic test showed IC50 of Rosella extract was 32.3 ± 2.15 µg/mL and IC50 of Doxorubicin was 2.68 ± 0.09 µg/mL. The antiproliferation test results in the control cell doubling time of 28.25 ± 0.21 hours while the concentration of Rosella extract at levels of 32.3; 16.15; and 8.08 µg/mL doubling time of 53.23 ± 0.20 hours, 39.02 ± 0.19 hours and 46.74 ± 0.23 hours so that it shows the inhibition of cell multiplication growth. The IC results show the combination of 4.04 µg/mL Rosella Flower Extract and 2.67 µg/mL Doxorubicin which is 0.0013 can be interpreted as a very strong synergistic effect (0.0013 ≤ 0.1). So it can be concluded the combination of ethanol extract Rosella flowers has antiproliferation properties through the mechanism of delaying the doubling time.
THE IMPACT OF PVA CONCENTRATION ON THE PHYSICAL QUALITY OF THE Eleutherine palmifolia (L.) Merr LEAVES PEEL-OFF GEL MASK Kumalasari, Eka; Prihandiwati, Erna; Ma'ruf, Muhammad; Ariani, Novia; Amelia, Senya Puteri; Fawwazi, Muhammad Hafizh Abiyyu Fathin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 2 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.2277

Abstract

The natives of Central Kalimantan utilize Eleutherine palmifolia (l.) Merr as a traditional medicine to treat various diseases. Eleutherine palmifolia  leaves are rich in flavonoid substances. Eleutherine palmifolia  leaves extract has an IC50 value of 45.33 ppm, indicating significant antioxidant activity. Antioxidants are helpful in reducing the risk of UV radiation-induced skin damage. Eleutherine palmifolia leaves have antioxidant properties that can be used as a peel-off gel mask. Polyvinyl alcohol (PVA) bases come in various formulations for peel-off gel mask that F1 10%, F2 12%, and F3 14%. The concentration of PVA is the most significant element affecting how well peel-off gel masks create films. This study aims to determine the impact of PVA concentration on the physical of the Eleutherine palmifolia  leaves Peel-off gel mask. All formulas are tested for organoleptics, homogeneity, spreadability, pH value, and drying speed. The results showed that all peel-off gel mask compositions pass the physical properties test. A one-way ANOVA statistical analysis reveals a significant variation in the preparations drying speeds (p<0,05).