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Meity M Laut
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Resistensi Larva Strongyle sp. Terhadap Albendazole pada Kambing Kacang (Capra hircus) di Indonesia Natasha Imanuelle; Meity M Laut; Dede Rival Novian
Jurnal Veteriner Nusantara Vol 6 No 1 (2023): Februari 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i1.2791

Abstract

Nematodiasis is a disease of livestock which caused by nematode infestation. Nematodes in the digestive tract inhibit livestock productivity and increase mortality in young animal. Generally speaking, control of nematodiasis is done by administering anthelmintic from benzimidazole group. Albendazole is the most commonly used anthelmintic. However, continuous use of albendazole in ruminants leads to the development of resistance. The present study aims to not only investigate and evaluate Strongyle sp. larvae resistance to albendazole in Indonesia but also to determine the incident rate of albendazole resistance. This study and references were obtained through Google Scholar and PubMed then arranged using Mendeley. The references are scientific journals, scientific articles, Ebooks and proceedings with "keywords" resistance of Strongyle sp. larvae to albendazole. All references were analyzed and evaluated systematically. The result show that the resistence of Strongyle larvae against albendazole occurred in West Java, East Java, and Yogyakarta with the results of the resistence test was 67%to 89%; 77% and 83%. This results shows that the ability of the drug to treat nematodiasis is no longer optimal. The risk factors of strongyle larvae resistence to albendazole are administering sntihelmintic from the same group continously with inapropriate dose and the ability of worms to develop resistence genes against albendazole.
Studi Kepustakan Uji Sensitivitas Antibiotik terhadap Escherichia coli Isolat Kecoak Monycha Bumbungan; Meity M Laut; Novalino H. G. Kallau
Jurnal Veteriner Nusantara Vol 5 No 1 (2022): Februari 2022
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v5i1.2987

Abstract

Kecoak merupakan vektor mekanis yang hidup berdampingan dengan manusia. Kecoak bertindak sebagai vektor karena terkait erat dengan keberadaan bakteri yang dibawa pada permukaan tubuhnya. Escherichia coli adalah bakteri yang tersebar di lingkungan yang dapat mengkontaminasi air dan tanah disekitarnya sehingga dapat disebarkan melalui vektor seperti kecoak. Penelitian ini bertujuan untuk mengetahui prevalensi Escherichia coli isolat kecoak dan profil uji sensitivitasnya terhadap antibiotik. Penelitian ini menggunakan pendekatan studi kepustakaan dengan melakukan penelusuran dan pengumpulan informasi dan data dari data base Google Cendekia. Data dan informasi dianalisis secara deskriptif dan dibahas berdasarkan hasil penelitian dari berbagai sumber. Hasil studi kepustakaan menunjukkan 100% (7/7) literatur penelitian dapat mengisolasi Escherichia coli dari tubuh kecoak dengan prevalensi rata-rata Escherichia coli 40,22%. Hasil uji sensitivitas beberapa literatur penelitian menunjukkan Escherichia coli isolat kecoak telah resisten terhadap antibiotik ampicillin, piperacillin, amoxicillin, penicillin, cloxacilin, ceftriaxone, cefuroxime, cephotaxime, cefepime, ceftazidime, erythromycin, gentamycin, streptomycin, amikacin, nalidixic acid, ciprofloxacin, ofloxacin, tetracycline, chloramphenicol dan vancomycin. Beberapa literatur penelitian juga melaporkan Escherichia coli isolat kecoak masih sensitif terhadap antbiotik vancomycin, ciprofloxacin, ofloxacin, imipenem, cefoperazone, gentamycin, ampicillin, methylaxone, tetracycline, chloramphenicol dan erythromycin.
Efektifitas Ekstrak Serai Dapur (Cymbopogon citratus) Sebagai Larvasida Nyamuk Culex Sp di Kota Kupang Agatha Sada Ua; Julianty Almet; Meity M Laut
Jurnal Veteriner Nusantara Vol 6 No 1 (2023): Februari 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i1.3022

Abstract

Beberapa penyakit disebabkan oleh nyamuk sebagai vektor, seperti demam berdarah dengue (DBD), malaria dan filariasis. Kota Kupang pada tahun 2018, terdapat 238 kasus DBD dan 35 kasus malaria. Berbagai upaya dilakukan untuk memutuskan siklus hidup nyamuk, salah satunya dengan menggunakan larvasida. Salah satu tanaman yang dapat digunakan sebagai larvasida adalah serai dapur (Cymbopogon citratus). Penelitian ini bertujuan untuk mengetahui nilai Lethal Concentration 50 (LC50) dari ekstrak serai dapur (Cymbopogon citratus). Pengujian ekstrak serai dapur (Cymbopogon citratus) sebagai larvasida dilakukan dengan menggunakan 25 ekor larva Culex sp pada setiap perlakuan dan diuji pada enam konsentrasi yaitu 0%; 0,2%; 0,4%; 0,6%; 0,8% dan 1% serta dilakukan pengulangan sebanyak tiga kali dan dilakukan pengamatan pada 2 jam, 4 jam, 12 jam dan 24 jam. Hasil penelitian menunjukkan kematian larva sebesar 5,3% (0%); 45,3% (0,2%); 70,6% 0,4%; 96% (0,6%); 100% (0,8% dan 1%). Hasil analisis probit menunjukkan nilai LC50 sebesar 0,412%, sehingga dapat disimpulkan bahwa ekstrak serai dapur (Cymbopogon citratus) efektif sebagai larvasida nyamuk Culex sp dan pada konsentrasi 0,412% ekstrak serai dapur (Cymbopogon citratus) mampu membunuh 50% dari jumlah larva uji.Salah satu tanaman yang dapat digunakan sebagai larvasida adalah serai dapur (Cymbopogon citratus). Penelitian ini bertujuan untuk mengetahui nilai Lethal Concentration 50 (LC50) dari ekstrak serai dapur (Cymbopogon citratus). Pengujian ekstrak serai dapur (Cymbopogon citratus) sebagai larvasida dilakukan dengan menggunakan 25 ekor larva Culex sp pada setiap perlakuan dan diuji pada enam konsentrasi yaitu 0%; 0,2%; 0,4%; 0,6%; 0,8% dan 1% serta dilakukan pengulangan sebanyak tiga kali dan dilakukan pengamatan pada 2 jam, 4 jam, 12 jam dan 24 jam. Hasil analisis probit menunjukkan nilai LC50 sebesar 0,412%, sehingga dapat disimpulkan bahwa ekstrak serai dapur (Cymbopogon citratus) efektif sebagai larvasida nyamuk Culex sp dan pada konsentrasi 0,412% ekstrak serai dapur (Cymbopogon citratus) mampu membunuh 50% dari jumlah larva uji.
Kajian Escherichia coli Resisten Antibiotik pada Lingkungan Air di Indonesia Yudith Elma Mauwalan; Novalino Kallau; Meity M Laut
Jurnal Veteriner Nusantara Vol 5 No 1 (2022): Februari 2022
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v5i1.3264

Abstract

Water is a natural resource that is needed by living things. Esherichia coli is one of the normal flora on digestive tract of humans and animals and is a parameter of drinking water quality because its presence in the water indicates the water is contaminated. Esherichia coli is abundant in water and is a reservoir associated with Antimicrobial Resistance (AMR). This literature review aims to determine the prevalence level of Escherichia coli in the water environment in Indonesia and the level of Escherichia coli resistant to β-lactam antibiotics and aminoglycoside antibiotics. This literature review is obtained from searching and collecting data and information from various reference sources using the Mendeley and Google Schoolar applications. Research data on Escherichia coli resistance were analyzed and evaluated and it was found that the prevalence of Escherichia coli in the water environment in Indonesia ranges from 33.33% to 100% and the level of antibiotic resistance in the β-lactam group (Amoxicillin 66.7%-100%, Ampicillin 100% and Penicillin 100%) and Aminoglycosides (Streptomycin 73.3%-86.7%, Tobramycin 100%, Gentamicin 100% and Kanamycin 33.3%) against Escherichia coli in the water resources in Indonesia.
Studi Literatur Uji Aktivitas Ekstrak Daun Kirinyuh (Chromolaena odorata) Sebagai Alternatif Pengobatan Myiasis yang Disebabkan oleh Chrysomya bezziana Diana Rabeka Otu; Nemay A Ndaong; Meity M Laut
Jurnal Veteriner Nusantara Vol 6 No 1 (2023): Februari 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i1.5370

Abstract

Myiasis is a disease in livestock caused by the larvae of the fly Chrysomya bezziana . Myiasis causes economic losses due to decreased productivity and tissue damage in livestock. Treatment of myiasis is by using synthetic insecticides, but the use of synthetic insecticides has a negative impact on animals, humans, and the environment. The use of synthetic insecticides can be replaced with botanical insecticides, one of the plants that can be used as antimyiasis is kirinyuh . Kirinyuh is a plant from the Asteraceae family which has been used as a botanical insecticide. This literature study aims to determine the potential of kirinyuh leaves as antimyiasis, the compounds contained in kirinyuh leaves and the mechanism of antimyiasis. This literature study uses 30 literature collected by browsing the Google Scholar database. Five literature states that kirinyuh leaves contain secondary metabolites of flavonoids, alkaloids, saponins, tannins and terpenoids. Meanwhile, 12 literatures describe the antimyiasis activity of these secondary metabolites. Flavonoids inhibit the nervous system and interfere with energy metabolism in the insect body, alkaloids interfere with the nervous system and reduce insect appetite, saponins as antifeedants and insect growth inhibitors, tannins interfere with insect digestion and growth, and terpenoids as inhibitors of nerve transmission in insects.
Studi Literatur Uji Aktivitas Ekstrak Etanol Daun Anting-Anting (Acalypha indica Linn.) Terhadap Penyembuhan Luka Bakar Pada Hewan Coba Devilia Rambu Athandau; Meity M Laut; Tri Utami
Jurnal Veteriner Nusantara Vol 6 No 2 (2023): Agustus 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i2.5663

Abstract

Burns are injuries that occur due to the body surface touching objects that produce heat, namely heat, radiation, electricity, and/or chemical either direct or indirect contact and resulting in skin damage or tissue loss. Treatment of burns can use chemical compounds or natural compounds from plants.Earring plant is one of the medicinal plants that can be used to heal burns. This literature study aims to determine the compounds contained in earring leaves and their mechanism of action in the process of healing burns. This literature study was conducted through searching and collecting literature using Google Schoolar and then analyzed descriptively. The literature used is 34 literatures that meet the criteria related to research topics with 29.41% discussing earring leaves, 29.41% discussing the pharmacological activity of secondary metabolites and 41.17% discussing wound healing. From the literature study, it is known that earring leaves contain aleurone compounds, flavonoids, alkaloids, saponins, steroids, triterpenoids, terpenoids, tannins, quinones, phenols and glycosides. These secondary metabolites have anti-inflammatory, antibacterial activity, stimulate the formation of new cells and stimulate the growth of collagen, antimicrobials and antioxidants, thereby accelerating burn healing. Wound healing is influenced by flavonoid compounds, alkaloids, saponins, tannins and phenols and affects the stages of inflammation, proliferation and maturation. To support these results, it is necessary to do laboratory research to prove it.
Studi Kepustakaan Pengendalian Infeksi Soil Transmitted Helminth Pada Ruminansia Di Lahan Kering Nusa Tenggara Timur Secara Kimia Dan Non-Kimia Ayu Yuliatri Manafe; Meity M Laut; Aji Winarso
Jurnal Veteriner Nusantara Vol 6 No 2 (2023): Agustus 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i2.9552

Abstract

Soil Transmitted Helminth (STH) is an intestinal nematode which in its life cycle requires soil for the maturation process. STH infection is classified as neglected disease, which is an infection that is not noticed and is chronic in nature because it does not cause typical clinical symptoms and the effects are only seen in the long term. The purpose of this study was to determine chemical and non-chemical control of STH infection on ruminants in dry land of NTT. The method used is a qualitative descriptive method with a literature study approach. Based on the results of the study, it was found that the chemical control of STH infection on ruminants in the dry land of NTT is from the benzimidazole group because it is easy to obtain, easy to apply and has good effectiveness, some of which are albendazole, mebendazole, levamisole, piperazine, pyrantel pamoate, and tiabendazole. Meanwhile, non-chemical effective control of STH infection can use several types of plants, including Putri malu extract (Mimosa pudica Linn.), katuk leaf extract, basil leaf extract (Ocimum americanum Linn.), soursop leaf extract (Annona muricata L.), alamanda leaf extract (Allamanda cathartica L.), mango arumanis (mangifera indica L.), and moringa leaf (Moringaoleifera L.) which have been studied contain chemical compounds that are beneficial such as anthelmintics, namely saponins, mimosin and tannins.
Efek Terapi Pemberian Vitamin E Terhadap Kerusakan Histopatologi Ginjal Tikus Putih (Rattus norvegicus) Yang Diinduksi Dexamethasone Padre Pio Kendok; Nemay A Ndaong; Meity M Laut
Jurnal Veteriner Nusantara Vol 7 No 1 (2024): April, 2024
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v7i1.11471

Abstract

The purpose of this study was to determine whether or not there was a therapeutic effect of vitamin E administration on dexamethasone-induced kidney histopathological damage of white rats. This study used 20 white rats (Rattus norvegicus) aged 2-3 months with a body weight of 200 grams divided into 5 groups, namely negative control (K) without dexamethasone and vitamin E, positive control group (P0) given dexamethasone subcutaneously at a dose of 0.13 mg / Kg BB, treatment group 1 (P1) given dexamethasone subcutaneously at a dose of 0.13 mg / Kg body weight and vitamin E orally at a dose of 150 mg / Kg body weight, treatment group 2 (P2) given dexamethasone subcutaneously at a dose of 0.13 mg / Kg body weight and vitamin E orally at a dose of 200 mg / Kg body weight, and treatment group 3 (P3) given dexamethasone subcutaneously at a dose of 0.13 mg / Kg body weight and vitamin E orally at a dose of 250 mg / kg body weight. Adaptation is carried out for 7 days. Experimental animals are then terminated and kidney organs are taken to make histopathological preparations with HE staining then the preparations are observed under a microscope. The observed parameter is damage to the glomerulus and proximal tubules of the kidneys. The results showed that dexamethasone was able to damage the kidneys characterized by necrosis of the glomerulus and hydropic degeneration of the proximal tubules of the kidneys shown in the positive control group (P0). In the group given vitamin E, only the P3 group with a dose of vitamin E 250 mg / kg body weight was able to provide a therapeutic effect on damage to the glomerulus and renal tubules due to the toxic effects of dexamethasone.
Uji Resistensi Campylobacter sp. Yang Diisolasi Dari Rusa Timor (Rusa Timorensis) Terhadap Antibiotik Sesarius Wahyu Pagung Jampur; Elisabet Tangkonda; Meity M Laut
Jurnal Veteriner Nusantara Vol 7 No 1 (2024): April, 2024
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v7i1.11899

Abstract

Timor deer (Rusa timorensis) is a protected animal and is categorized as vulnerable in the International Union for Conservation of Nature of Threatened Species Red List (IUCN Red List). Efforts to save and prevent timor deer from extinction are through conservation in captivity. Captive-bred timor deer can be infected with Campylobacter sp. which is one of the causes of diarrhea in humans. Antibiotic resistance to Campylobacter sp. has been widely reported in various parts of the world. Timor deer are not directly exposed to antibiotics but can experience antibiotic resistance due to interactions with humans. The purpose of this study was to determine resistance and determine the level of resistance of Campylobacter sp. isolated from timor deer to antibiotics. This research was conducted using Campylobacter sp. isolates on modified charcoal-cefoperazone-deoxycholate agar (mCCDA) media. Kirby-Bauer method resistance test with Mueller-Hinton agar media using test antibiotics: ampicillin, ciprofloxacin, erythromycin, chloramphenicol, and tetracycline. Data were analyzed by looking at the inhibition zone formed and compared with Clinical and Laboratory Standards Institute (CLSI) standards. The results showed that Campylobacter sp. from timor deer had developed resistance to ampicillin, erythromycin, and tetracycline antibiotics. The inhibition zones formed from the five types of test antibiotics were ampicillin (7.58 mm), ciprofloxacin (26.76 mm), erythromycin (11.65 mm), chloramphenicol (24.40 mm), and tetracycline (9.05 mm).
Co-Authors Agatha Sada Ua Aji Winarso Ayu Yuliatri Manafe Devilia Rambu Athandau Diana Rabeka Otu Julianty Almet Kallau, Novalino Harold Geoffrey Monycha Bumbungan Natasha Imanuelle Nemay A Ndaong Novian, Dede Rival Padre Pio Kendok Sesarius Wahyu Pagung Jampur Tangkonda, Elisabet Tri Utami Yudith Elma Mauwalan