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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Community Development Journal: Jurnal Pengabdian Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Medical Sains : Jurnal Ilmiah Kefarmasian
Rodhia Ulfa
Sekolah Tinggi Ilmu Farmasi Riau, Kamboja Street, Pekanbaru, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Development of black cumin seed oil (Nigella sativa L.) SNEDDS into solid-SNEDDS and its characterization Rodhia Ulfa; Dwi Utami; Iis Wahyuningsih
Pharmaciana Vol 11, No 2 (2021): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (369.931 KB) | DOI: 10.12928/pharmaciana.v11i2.18230

Abstract

Black cumin seed oil (MBJH) (Nigella sativa L.) is a well-known herb with pharmacology activities such as anticancer and anti-thrombocytopenia. The limitation of MBJH has poor absorption when using oral dosage form. The liquid SNEDDS (Self-nanoemulsifying drug delivery system) of MBJH as an alternative formulation. However, the disadvantage of liquid-SNEDDS of MJBH was the interaction between the active ingredients with soft gelatin capsules. Hence, this study proposed to develop solid-SNEDDS as a new formulation of MBJH. Solid-SNEDDS of MBJH was prepared from liquid-SEDDS of MBJH by adsorption to solid carrier method, consisting of aerosil and crospovidone as the adsorbent. The characterization of S-SNEDDS was determined by emulsification time and percent transmittance. Micromeritics properties of S-SNEDDS such as the angle of repose, bulk and tap density parameter, compressibility index, and Hausner ratio were measured  before and after stored in stress condition (40 ̊ C ± 2 ̊ C and relative humidity of 75% ± 5% for 14 days). The result showed S-SNEDDS of MBJH with aerosil absorbent had better S-SNEDDS performance in both characteristics and micromeritics properties under stress conditions than crospovidone absorbent. In conclusion, the s-SNEDDS of black cumin oil by solid aerosil carrier method is promising for future research development of S-SNEDDS dosage form.
VALIDATION OF SPECTROPHOTOMETRIC METHOD TO QUANTIFY QUERCETIN IN THE IN VITRO DISSOLUTION STUDY OF SELF NANO-EMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) Wildan Khairi Muhtadi; Ferdy Firmansyah; Tiara Tri Agustini; Pricillia Rahayu; Siti Arifah Fitriyanti; Rodhia Ulfa
Jurnal Farmasi Sains dan Praktis Vol 8 No 3 (September-December 2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v8i3.6258

Abstract

Quercetin possesses low solubility and decreases oral bioavailability. One way to increase the bioavailability of quercetin is by formulating a self-nanoemulsifying drug delivery system (SNEDDS). In vitro dissolution testing of SNEDDS needs to be carried out using a validated analytical method. This study aims to validate the quercetin analytical method in in vitro dissolution testing. Validation was carried out with two solvents, namely hydrochloric acid buffer pH 1.2 (HCl-1,2) and phosphate buffer pH 6.8 (PO-6.8). It tested some parameters, including linearity, detection limit (LoD), quantification limit (LoQ), accuracy, and precision. The quercetin calibration curve for both solvents has a value of r≥0.999. The LoD at HCl-1,2 and PO-6,8 were 0.26 ppm and 0.27 ppm, respectively. The LoQ of HCl-1,2 and PO-6,8 were 0.86 ppm and 0.91 ppm, respectively. The percentage recovery in both solvents was in the range of 80-110%. The relative standard deviation of the two solvents was less than 7.3%. The quercetin analytical method has been successfully validated as indicated by the results of linearity, detection limit, quantification limit, accuracy, and precision that met the requirements
REVIEW: PHYSICAL CHARACTERISTICS, ANTIOXIDANT, ANTIBACTERIAL AND WOUND HEALING EFFECTS OF BASIL LEAVES IN SEVERAL TYPES OF PHARMACEUTICAL BASES Rodhia Ulfa; Wildan Khairi Muhtadi; Nesa Agistia; Haiyul Fadhli
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.855

Abstract

Topical preparations are dosage forms applied to the skin for local therapy. These topical preparations contain several types of bases that are used for drug formulations. This review aimed to determine the type of base that is effective and widely used in basil leaf preparations that function as antioxidants, antibacterial agents, and in wound healing. The research method is comparative, namely, reviewing research articles on formulations of basil leaf products with various concentrations of base types, hydrogels, emulgels, lotions, hydrocarbons, water solubility, absorption, water washing, M/A-type creams, and pastes. The recommended formulation is a gel base type that has physical characteristics, non-irritating properties, antioxidant activity, antibacterial activity, and wound healing. This review contained articles published in the last 10 years.  Keywords: basil leaves, base type, physical characteristics, basil leaves, pharmacological activity
REVIEW: PHYSICAL CHARACTERISTICS, ANTIOXIDANT, ANTIBACTERIAL AND WOUND HEALING EFFECTS OF BASIL LEAVES IN SEVERAL TYPES OF PHARMACEUTICAL BASES Rodhia Ulfa; Wildan Khairi Muhtadi; Nesa Agistia; Haiyul Fadhli
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.855

Abstract

Topical preparations are dosage forms applied to the skin for local therapy. These topical preparations contain several types of bases that are used for drug formulations. This review aimed to determine the type of base that is effective and widely used in basil leaf preparations that function as antioxidants, antibacterial agents, and in wound healing. The research method is comparative, namely, reviewing research articles on formulations of basil leaf products with various concentrations of base types, hydrogels, emulgels, lotions, hydrocarbons, water solubility, absorption, water washing, M/A-type creams, and pastes. The recommended formulation is a gel base type that has physical characteristics, non-irritating properties, antioxidant activity, antibacterial activity, and wound healing. This review contained articles published in the last 10 years.  Keywords: basil leaves, base type, physical characteristics, basil leaves, pharmacological activity
REVIEW: ANTIBACTERIAL, ANTIFUNGAL AND WOUND HEALING ACTIVITY OF NANOEMULGEL FORMULATIONS AND PHYSICAL CHARACTERISTICS Rodhia Ulfa; Wildan Khairi Muhtadi; Urva Fresiva; Amraini Amelia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1193

Abstract

Nanoemulgel is an emulsion preparation with a droplet size of 1–100 nm suspended in a hydrogel. This review delves into the research on the impact of incorporating excipient components in nanoemulgel formulations to create products with specific physical attributes for different active ingredients with antifungal, antibacterial, and wound-healing properties. The research approach involves comparing articles on nanoemulgel preparation formulations with different combinations of active ingredients and excipients, as well as their pharmacological effects. Enhancing the level of active ingredients and altering the excipients can boost the effectiveness of nanoemulgel formulations in combating fungi, bacteria, and promoting wound healing. The review includes articles published within the past decade. Keywords: Nanoemulgel, Pharmacological activity, Physical characteristics, Review
Peningkatan pengetahuan terhadap sosialisasi dagusibu pada siswa SMA An Namiroh kota Pekanbaru Meiriza Djohari; Adriani Susanti; Rodhia Ulfa; Ana Bella Parina; Atika Putri; Azhariah Fadila; Bintang Bayu Winekas; Bonita Dwi Setyowati; Dea Adilla; Delfi Amrianis; Dinda Farahdilla; Rahmi Asrina Rizki; Ulfha Ikhwani; Yori Yunita Sinulingga
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 3 (2024): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i3.25929

Abstract

AbstrakIkatan Apoteker Indonesia melakukan edukasi baru yang disebut DAGUSIBU, yang merupakan singkatan dari "Dapatkan, Gunakan, Simpan, dan Buang". Dengan mengikuti langkah-langkah yang diuraikan dalam program DAGUSIBU yang dimulai dengan perolehan obat-obatan dan diakhiri dengan pembuangannya. Salah satu lapisan masyarakat yang sejak dini harus mengetahui tentang penggunaan obat adalah Siswa SMA. Untuk memastikan siswa tidak melakukan kesalahan dalam menggunakan obat, kegiatan sosialisasi DAGUSIBU dilaksanakan karena siswa masih belum memiliki cukup informasi tentang cara menggunakan obat yang benar.  Siswa SMA An Namiroh Kota Pekanbaru mengikuti sosialisasi DAGUSIBU dengan menggunakan kuesioner sebelum dan sesudah tes untuk mengukur pengetahuan mereka. Sebanyak 50 siswa yang mengikuti sosialisasi menunjukkan terjadinya peningkatan pengetahuan yaitu dari 75% pada pretest menjadi 93,4% pada posttest. Hasil menunjukkan bahwa pemahaman siswa terhadap DAGUSIBU dapat meningkat sebesar 18,4% ketika sosialisasi ini diadakan. Kata kunci: dagusibu; pengetahuan; obat. AbstractThe Indonesian Pharmacists Association is conducting a new education program called DAGUSIBU, which stands for “Get, Use, Store, and Dispose”. By following the steps outlined in the DAGUSIBU program that starts with the acquisition of medicines and ends with their disposal. One of the layers of society that should know about the use of medicines from an early age is high school students. To ensure that students do not make mistakes in using medicines, DAGUSIBU socialization activities are carried out because students still do not have enough information about how to use medicines correctly.  Students of An Namiroh High School in Pekanbaru City participated in the DAGUSIBU socialization using pre- and post-test questionnaires to measure their knowledge. A total of 50 students who participated in the socialization showed an increase in knowledge from 75% in the pretest to 93.4% in the posttest. The results show that students' understanding of DAGUSIBU can increase by 18.4% when this socialization is held. Keywords: dagusibu; knowledge, medicine.
A Literature Review On the Formulation, Characterization, and Stability of Cinnamomum burmannii Emulgel Extract as an Antioxidant and Sunscreen Rodhia Ulfa; Ferdy Firmansyah; Fenny Khairunnisa; Putri Lestari
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 21, No 1 (2024): Jurnal Ilmu Farmasi & Farmasi Klinik
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v21i1.9126

Abstract

Emulgel is a pharmaceutical formulation that integrates the characteristics of both emulsions and gels, resulting in a semisolid product. The utilization of emulgel formulations has been shown to enhance the efficacy of drug delivery by facilitating deeper skin penetration and subsequently augmenting its pharmacological activity. The antioxidant and sunscreen properties of cinnamon bark extract make it suitable for incorporation into an emulgel formulation. Variations in the concentration of extracts and gelling agents can have an impact on the physical properties, stability, and pharmacological efficacy of the emulgel. The objective of this review is to ascertain the optimal concentrations of extracts and gelling agents in emulgel formulations for enhanced efficacy. The employed methodology entails conducting a comprehensive review of scholarly articles pertaining to emulgel formulations containing cinnamon bark extract. These formulations encompass a range of concentrations of both the extract itself and gelling agents, while also possessing antioxidant and sunscreen properties. The formulation that is recommended is one that satisfies the criteria pertaining to its physical attributes, stability, and pharmacological efficacy. The emulgel formulation that best meets the specified criteria consists of a 1% concentration of cinnamon bark extract in combination with the gelling agent Viscolam MAC 5%.
OPTIMALISASI PENGGUNAAN OBAT MAAG DAN GERD SELAMA BULAN PUASA: EDUKASI KESEHATAN BAGI SISWA MAN 3 KOTA PEKANBARU Benni Iskandar; Neni Frimayanti; Rodhia Ulfa; Irfan Maulana; Haryeni Sastra Anggraini; Kolista Sisilawati; Lala Azela; Mazaya Putri Anabesi; Mulia Rizki; Mutiara Salsabillah; Nadea Zahra Ramadhani; Nadila Putri; Nisa Novrianti
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2025): Volume 6 No. 2 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i2.44093

Abstract

Selama bulan Ramadan, individu Muslim yang menderita penyakit maag dan gastroesophageal reflux disease (GERD) mengalami perubahan pola konsumsi obat akibat periode puasa yang berlangsung antara 11 hingga 18 jam. Penyesuaian jadwal ini dapat memengaruhi farmakokinetik obat, berpotensi mengurangi efektivitas terapi jika tidak dikelola dengan baik. Oleh karena itu, edukasi kesehatan menjadi krusial untuk memastikan pemahaman yang tepat mengenai aturan dan waktu penggunaan obat selama berpuasa guna mencapai efek terapi yang optimal. Kegiatan pengabdian ini bertujuan untuk meningkatkan pengetahuan siswa MAN 3 Kota Pekanbaru tentang penggunaan obat maag dan GERD yang rasional selama bulan Ramadan. Metode yang digunakan mencakup penyuluhan interaktif yang didukung dengan media edukasi berupa leaflet dan presentasi PowerPoint. Efektivitas edukasi diukur melalui pre-test dan post-test dengan lembar checklist sebagai instrumen evaluasi. Hasil analisis menggunakan uji Wilcoxon menunjukkan peningkatan signifikan dalam tingkat pengetahuan siswa setelah edukasi, dengan nilai p = 0,000 (p < 0,05). Temuan ini menegaskan bahwa penyuluhan berbasis ceramah, didukung oleh leaflet, secara efektif meningkatkan pemahaman siswa tentang penggunaan obat maag dan GERD selama bulan puasa.
Co-Authors Adriani Susanti agistia, nesa Agustini, Tiara Tri Amraini Amelia Ana Bella Parina Atika Putri Azhariah Fadila BENNI ISKANDAR Bintang Bayu Winekas Bonita Dwi Setyowati Dea Adilla Delfi Amrianis Dinda Farahdilla Fenny Khairunnisa Ferdy Firmansyah Haiyul Fadhli Haryeni Sastra Anggraini Iis Wahyuningsih Irfan Maulana Kolista Sisilawati Lala Azela Mazaya Putri Anabesi Meiriza Djohari, Meiriza Muhammad Yusron Maulana El-Yunusi Muhtadi, Wildan Khairi Mulia Rizki Mutiara Salsabillah Nadea Zahra Ramadhani Nadila Putri Neni Frimayanti Nisa Novrianti Pricillia Rahayu Putri Lestari Rahmi Asrina Rizki Siti Arifah Fitriyanti Ulfha Ikhwani Urva Fresiva Wildan Khairi Muhtadi Yori Yunita Sinulingga