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All Journal Medical Journal of Indonesia Gender Equality: Internasional Journal of Child and Gender Studies Jurnal Manajemen Pelayanan Publik Jurnal AKSI (Akuntansi dan Sistem Informasi) International Journal of Supply Chain Management Jesya (Jurnal Ekonomi dan Ekonomi Syariah) JASa (Jurnal Akuntansi, Audit dan Sistem Informasi Akuntansi) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal Research of Social Science, Economics, and Management Jurnal Riset Pangan dan Gizi Jurnal Penyakit Dalam Indonesia
Dyah Purnamasari
Department Of Internal Medicine, Faculty Of Medicine, Universitas Indonesia, Jakarta
Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health Social Sciences Transportation

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Sunlight–derived vitamin D affects interleukin-4 level, T helper 2 serum cytokines, in patients with Graves’ disease: a prospective cohort study Purnamasari, Dyah; Soewondo, Pradana; Djauzi, Samsuridjal
Medical Journal of Indonesia Vol 24, No 4 (2015): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.046 KB) | DOI: 10.13181/mji.v24i4.1270

Abstract

Background: Graves’ disease (GD) is the most common autoimmune disease leading to hyperthyroidism. The role of Th1/Th2 pathways balance in GD is still controversial. Vitamin D is reported to have an effect on those pathways. This study aims to examine the effect of sunlight exposure on vitamin D 25(OH) level and Th1 and Th2 pathway-derived cytokines in GD patients. Methods: A prospective cohort study was conducted on 32 GD patients to compare the effect of sunlight exposure on vitamin D level and cytokines of Th1 and Th2 pathways between exposed and unexposed groups. Exposed group received sunlight exposure three times a week for 30 minutes each between 9–11 a.m for 1 month. Thyroid stimulating hormone (TSH), free thyroxin (fT4), vitamin D 25(OH), interferon-γ (IFN-γ) and interleukin-4 (IL-4) serum levels, were investigated before and after one month of sunlight exposure. Paired t-test or Mann Whitney test were used to analyze the difference between exposed and unexposed GD groups before and after sun exposure.Results: One month of sunlight exposure increased vitamin D 25(OH) level by 27.90% among exposed GD group (15.34 ng/mL to 19.62 ng/mL, p<0.001). Meanwhile, unexposed GD group’s vitamin D 25(OH) level decreased from 20.48 ng/mL to 18.86 ng/mL (p<0.001). Increased vitamin D 25(OH) level in exposed group was not accompanied by the increase of IL-4 level after sunlight exposure.Conclusion: Sunlight exposure increases vitamin D 25(OH) serum level and may affect the level of IL-4, Th2 pathway-derived cytokine, in patients with GD. However, the role of sunlight-derived vitamin D on IFN-γ in GD patients can not be concluded in this study.
The Effect of Sales Growth and Leverage on Tax Avoidance Empirical Study of Coal Sub-Sector Mining Companies Listed on the Indonesia Stock Exchange in 2014-2018 Nadya, Bella; Purnamasari, Dyah
Jurnal AKSI (Akuntansi dan Sistem Informasi) Vol 5, No 2 (2020)
Publisher : Politeknik Negeri Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32486/aksi.v5i2.538

Abstract

This study aims to determine the influence of sales growth and leverage on tax avoidance on coal sub-sector mining companies listed on the IDX in 2014-2018. The data used were secondary data and the samples were financial statements from 10 coal sub-sector mining companies listed on the IDX in 2014-2018. The method of sample selection was purposive sampling, while the data analysis included panel data regression analysis. The data were analyzed using Eviews 10 software. The results of this study show that sales growth and leverage affect tax avoidance. Suggestions for further research is to add research model variables that influence tax avoidance.
Liver Fibrosis and Steatosis in Virally Suppressed HIV-Infected Patients with Cytomegalovirus Seropositivity Chyntia Olivia Maurine Jasirwan; Adik Wibowo; Amal C Sjaaf; Gita Aprilicia; Dyah Purnamasari; Evy Yunihastuti; Rino Alvani Gani
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 3 (2021): VOLUME 22, NUMBER 3, December 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (6096.609 KB) | DOI: 10.24871/2232021180-187

Abstract

Background: Cytomegalovirus (CMV) is a human herpesvirus common in people with human immunodeficiency virus (HIV). In a patient with immunocompetence, long periodic asymptomatic CMV might affect to develop the abnormal liver function and contribute to non-AIDS defining morbidity, including chronic liver disease. This study aims to know the prevalence of liver fibrosis and steatosis in virally suppressed HIV infected patients with CMV reactive and summarize the correlation of clinical presentation with liver fibrosis and steatosis in these subjects.Method: A cross-sectional study in HIV Integrated Care Unit, Cipto Mangunkusumo Hospital, was conducted from April 2019 until June 2020. Subjects enrolled in this study were suppressed HIV patients aged between 30-40 years with positive IgG CMV and already using stable ART for at least one year. Transient elastography measured the liver stiffness. Patients with liver stiffness above 7 kPa were defined as having significant liver fibrosis. In addition, Spearman correlation was conducted to evaluate the correlation of clinical presentation of subjects related to liver fibrosis and steatosis. Results: A total of subjects was included in this study. Dominantly male (62.5%) with average age 38 ± 4.68 years. The median amount of CMV DNA was 466 (17-21284) copy/ml. Significant Fibrosis was found in 17/80 (21%) subjects. In this study, clinical parameters correlated with liver fibrosis were insulin, glucose fasting, Homa IR, triglyceride, HDL, and platelet. A medium positive correlation was found in insulin, and Homa IR, with coefficient correlation for insulin, was r = 0.475, p 0.001; and coefficient correlation for Homa IR was r = 0 .487, p 0.001.Conclusion: The prevalence of liver fibrosis was 12% in these subjects. In addition, insulin and Homa IR had a positive correlation with increasing liver fibrosis.
Faktor-Faktor yang Berperan terhadap Terjadinya Lipodistrofi pada Pasien HIV yang Mendapatkan Terapi Antiretroviral Lini Pertama Kusumayanti, Ratu Ratih; Yunihastuti, Evy; Purnamasari, Dyah; Witjaksono, F; Dewiasty, Esthika
Jurnal Penyakit Dalam Indonesia Vol. 2, No. 4
Publisher : UI Scholars Hub

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Abstract

Pendahuluan. Seiring dengan perkembangan antiretroviral, harapan hidup pasien HIV terus meningkat namun menjadi rentan terhadap efek samping pengobatan. Salah satu efek samping pengobatan adalah sindrom lipodistrofi, meliputi lipoatrofi, lipohipertrofi, atau gabungan keduanya. Faktor risiko yang dikaitkan dengan lipodistrofi pada HIV adalah usia, jenis kelamin, lama terapi antiretroviral, CD4 awal, Stadium HIV, dan pemakaian Stavudin. Belum ada publikasi di Indonesia yang meneliti kejadian lipodistrofi pada populasi pasien HIV yang mendapat terapi ARV lini pertama serta faktor-faktor yang memengaruhinya. Berdasarkan hal tersebut, penelitian ini dilakukan untuk mengetahui kejadian lipodistrofi pada pasien HIV dalam terapi ARV lini pertama berbasis Stavudin dan Zidovudin minimal 6 bulan serta faktor-faktor yang memengaruhinya yang berobat di Pokdisus RSCM. Metode. Penelitian dilakukan dengan desain potong lintang dan kasus kontrol untuk mengetahui prevalensi lipodistrofi pada pasien HIV dengan ARV lini pertama serta faktor-faktor yang memengaruhinya. Analisis statistik menggunakan uji chi square atau uji Kolmogrof Smirnoff untuk mendapatkan hubungan antara masing-masing faktor risiko dengan terjadinya lipodistrofi. Analisis multivariat dilakukan dengan regresi logistik. Hasil. Sebanyak 346 pasien terlibat dalam penelitian ini. Didapatkan prevalensi lipodistrofi sebesar 27,5%, dengan rincian 70,5% lipoatrofi, 8,4% lipohipertrofi, dan 21,1% gabungan keduanya. Lokasi lipoatrofi terbanyak di daerah wajah. Prevalensi lipodistrofi pada subjek yang menggunakan Stavudin sebesar 43.3%, dan Zidovudin sebesar 10,7%. Faktor yang berhubungan dengan kejadian lipodistrofi adalah penggunaan Stavudin [p= Simpulan. Didapatkan prevalensi Lipodistrofi pada pasien HIV yang mendapatkan terapi ARV lini pertama adalah 27.5%, dan didapatkan hubungan antara kejadian lipodistrofi pada pasien HIV dengan penggunaan Stavudin.
The Association between Vitamin D 25(OH)D Level andAlbuminuria in Type 2 Diabetes Mellitus Indra, Tities Anggraeni; Lydia, Aida; Purnamasari, Dyah; Setiati, Siti
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 1
Publisher : UI Scholars Hub

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Abstract

Introduction. Vitamin D 25(OH)D deficiency was reported as a possible risk factor for the development of diabetic nephropathy in several epidemiologic studies. Whether vitamin D 25(OH)D deficiency plays a role in the development of diabetic nephropathy in Indonesia is unknown. This study aims to determinate the association between vitamin D 25(OH)D level with albuminuria in patients with type 2 diabetes mellitus in Indonesia. Methods. A cross-sectional study was conducted in 96 patients with type 2 diabetes mellitus at outpatient clinic of MetabolicEndocrine Cipto Mangunkusumo Hospital. Serum vitamin D level was assessed using Diasorin kit with CLIA method, while albuminuria was assessed using random urine sample. Statistical analysis was conducted using chi square for bivariate analysis and regression logistic method for multivariate analysis. Results.The prevalence of vitamin D 25(OH)D deficiency in patients with type 2 diabetes mellitus was 49% with a median value 16,35 (4,2-41,4) ng/mL. There was no significant correlation between vitamin D deficiency with the severity of albuminuria (OR 0,887; 95% CI 0,335 to 2,296). Confounding factors such as poor blood glucose control and overweight strongly influenced the association between vitamin D deficiency with the incidence of albuminuria in patients with type 2 diabetes mellitus. Conclusion. The results of this study showed that there was no association between vitamin D deficiency with the severity of albuminuria in patients with type 2 diabetes mellitus in Indonesia.
Association of Glucose Variability in the First 72 Hours of ICUCare with ICU Mortality in Critically-III Patients Yasmine, Elizabeth; Mansjoer, Arif; Purnamasari, Dyah; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 3, No. 1
Publisher : UI Scholars Hub

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Abstract

Introduction. Hyperglycemia during hospitalization is a risk factor that can be managed in order to reduce mortality. Inspite of hyperglycemia, glucose variability also brings negative outcome to cells. Studies about glucose variability effect to mortality had been studied using many variables of glucose variability. Methods. Retrospective cohort study is done to 280 critical ill patient in ICU and HCU in Cipto Mangunkusumo Hospital who admitted to critical care between January 2012-August 2013. MAG change and glucose standard deviation are divided into 4 quartiles. Relationship between MAG change and glucose standard deviation are analyzed using Chi Square test. To control the confounders (MSOFA score, Charlson comorbidities index, hypoglycemia, and hyperglycemia), logistic regression is done Results. Median of MAG change is 3.3 mg/dL/hour and median of glucose standard deviation is 37.63 mg/dL. Mortality proportion is higher in upper quartile of MAG change and glucose standard deviation compared to lower quartile. OR of upper quartile MAG change to ICU mortality is OR 4.26 (95% CI 1.98-9.15) and OR of upper quartile glucose standard deviation to ICU mortality is OR 2.78 (95% CI 1.35-5.71). These results are adjusted to MSOFA score, hypoglycemia, and hyperglycemia. In logistic regression test, fully adjusted OR are 3.34 (95% CI 1.08-10.31) and 0.90 (95% CI 0.28-2.88) for MAG change and glucose standard deviation, respectively. Conclusions. Mortality proportion of upper quartile of MAG change (>8.1 mg/dL/hour) is higher than lower quartile (59 mg/dL) is higher than lower quartile(<22.7 mg/dL), but the difference is not statistically significant.
The Role of Paternal History of Type 2 Diabetes Mellitus on Prediabetes Status among The Offspring of Type 2 Diabetes Mellitus Patients Ekaputri, Maulidia; Citrawijaya, Henrico; Sudirman, Adrian Reynaldo; Jonathan, Kevin; Murti, Radityo Alu; Balqis, Ayu Putri; Purnamasari, Dyah
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 4
Publisher : UI Scholars Hub

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Abstract

Faktor-Faktor yang Memengaruhi Kualitas Hidup Pasien Gagal Jantung Kronik Fraksi Ejeksi Terjaga (HFpEF) Rawat Jalan di RSUPN Dr. Cipto Mangunkusumo Pratama, Derin Anugrah; Nasution, Sally Aman; Muhadi, Muhadi; Mansjoer, Arif; Alwi, Idrus; Purnamasari, Dyah; Lydia, Aida; Tahapary, Dicky Levenus
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 1
Publisher : UI Scholars Hub

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Abstract

Introduction. The prevalence of heart failure in Indonesian adults is 1.5%, at least half of which categorized as heart failure with preserved ejection fraction (HFpEF). Quality of life assessment plays an important role in the management of heart failure, one of the tools widely used is the Minnesota Living with Heart Failure (MLHF) questionnaire. In Indonesia, there is still no data regarding risk factors that affect the quality of life of HFpEF patients. This study aimed to determine the quality of life profile of HFpEF patients and the relationship between the risk factors (age, hypertension, DM, smoking, and obesity) on the quality of life of HFpEF patients. Methods. A cross-sectional study was conducted. Data was collected from adult HFpEF (based on echocardiography in the last 6 months) patients (>18 years old) who visited the Cardiology Clinic at Cipto Mangunkusumo Hospital from January 2022 to December 2023. Quality of life was measured using the MLHF questionnaire. Bivariate analysis was performed to find the relationship between risk factors (age, gender, hypertension, DM, smoking, and obesity) and patients’ quality of life. Multivariate analysis was performed for hypertension, DM, gender, and age variables. Results. Out of 206 subjects, 72.33% of patients were dominant in the physical domain items, and 27.67% of patients were dominant in the emotional domain items. The majority of patients dominant in physical items had overall good quality of life. The majority of patients dominant in emotional items also had good quality of life. No significant relationship was found between the dominant domain item and the quality of life in HFpEF patients. We also found that there was no significant relationship between socio-demographic factors and risk factors for dominant domain items. However, there was a significant relationship between age (p=0.005), gender (p=0.001), and smoking history (p=0.001) with the quality of life in HFpEF patients. Adult patients had a poorer quality of life compared to elderly patients (OR= 0.33 [95% CI 0.17-0.66]). No significant relationship was found between hypertension, diabetes mellitus, dyslipidemia, and obesity with the quality of life in HFpEF patients. Conclusions. There is a statistically significant relationship between age, gender, and smoking history with the quality of life in HFpEF patients. Meanwhile, there is no significant relationship between hypertension, diabetes mellitus, and obesity with the quality of life in HFpEF patients.
The wisdom of ecofeminism in Arjasari as a link between Hadith and community practice Daffa, Muhammad; Purnamasari, Dyah
INTERNATIONAL JOURNAL OF CHILD AND GENDER STUDIES Vol 10, No 1 (2024)
Publisher : Universitas Islam Negeri Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/equality.v10i1.19835

Abstract

This research aims to discuss ecological wisdom in Arjasari as a link between hadith and community practice. This qualitative research used a case study. It used hadith science theory as the formal object, and the practice of ecofeminism the material object. Using observation, interviews, and documentation for data collection, this study analyzed the data through inventory, classification, and interpretation stages. The research involved two community organizations affiliated with the Sapa Institute: Bale Istri Community and Islamic Organization in Arjasari, Bandung, Indonesia, from July 2022 to December 2022. This research is unique because it explores thematic hadiths, which serve as a basic source for integrating Islamic teachings into the practice of ecofeminism. This study explores the matan of traditions related to ecology, using a thematic approach to understand their relevance to contemporary environmental challenges comprehensively. The research shows that ecofeminism practices of community organizations from the perspective of hadith were found in Arjasari Village, Bandung. The identified hadiths emphasize responsible land use, sustainable agriculture, and preservation of natural resources, contributing to developing an ecofeminist framework in Arjasari, harmonizing Islamic values with environmental ethics. This study's unique contribution lies in exploring thematic hadith, which integrates ecofeminist practices. The deliberate linkage of religious principles with ecofeminist discourse promotes the equivalence between environmental standards and Islamic values.
Efforts to Improve the Public Service Quality: Implementation of a Modern Electronic Tax System, Self-Efficacy, and Taxpayer Compliance Purnamasari, Dyah; Tahir, Rusdin
Jurnal Manajemen Pelayanan Publik Vol 9, No 1 (2025): Jurnal Manajemen Pelayanan Publik
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jmpp.v9i1.58803

Abstract

The success of tax revenue depends on the effectiveness of tax administration that improves taxpayer compliance, the quality of public services, and the uniform implementation of tax provisions. This study aims to explore the factors that affect the quality of public services with a focus on taxpayer compliance, including the influence of e-registration, e-filing, e-efficacy, and digital literacy. A quantitative approach was used with a survey of 535 respondents (416 individual taxpayers and 119 fiscal authorities) at the Directorate General of Taxes of West Java I, II, and III. Statistical analysis was carried out using SEM with the Lisrel application. The results of the study show that e-registration has a positive and significant effect on taxpayer compliance, while e-filing affects compliance but is not significant. Self-efficacy has a positive and significant effect on taxpayer compliance, while digital literacy has an effect but is not significant. At the same time, e-registration, self-efficacy, e-filing, digital literacy, and taxpayer compliance have a positive and significant effect on the quality of public services. These findings make a theoretical contribution by clarifying the factors affecting taxpayer compliance and practical implications for improving tax administration strategies that can improve taxpayer engagement and compliance.
Co-Authors Adik Wibowo Ahmad Fariz M.Z Zein, Ahmad Fariz M.Z Aida Lydia, Aida Amal C Sjaaf Anandhara Indriani Khumaedi, Anandhara Indriani Annisha, Zakiah Apriwandi . Arif Mansjoer Arwaty, Dini Balqis, Ayu Putri Barus, Irene Sukma Lestari Catarina Budyono, Catarina Chyntia Olivia Maurine Jasirwan, Chyntia Olivia Maurine Citrawijaya, Henrico Cleopas M Rumende, Cleopas M Daffa, Muhammad Dicky Levenus Tahapary E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Ekaputri, Maulidia Elizabeth Yasmine, Elizabeth Esthika Dewiasty, Esthika Evy Yunihastuti F Witjaksono, F Gita Aprilicia Hiya Alfi Rahmah Idrus Alwi Ika P Wijaya, Ika P Jonathan, Kevin Laksono, Radi Laras Budiyani, Laras Marcellus Simadibrata Mohd Saudi, Mohd Haizam Muhadi Muhadi, Muhadi Murdani Abdullah Murti, Radityo Alu Nadya, Bella Patricia Sari, Vena Pradana Soewondo Pratama, Derin Anugrah Ratu Ratih Kusumayanti Rino Alvani Gani Rusdi, Muhammad Adhi Rusdin Tahir, Rusdin Sally A Nasution, Sally A Sally Aman Nasution, Sally Aman Samsuridjal Djauzi Siti Marhamah, Siti Siti Setiati Stevent Sumantri, Stevent Sudirman, Adrian Reynaldo Tities Anggraeni Indra, Tities Anggraeni Wijaya, Aida Yuniarti Soeroso Zaman, Dr. Fazluz