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HUBUNGAN ANTARA PENGETAHUAN DAN KETERAMPILAN VULVA HIGIENE DENGAN KEJADIAN KEPUTIHAN PADA IBU RUMAH TANGGA (STUDI DI DESA SAWAHJOHO WARUNGASEM BATANG) Melati, Rika; Santoso, Eko Jemi; -, Sayono
Karya Ilmiah S.1 Ilmu Keperawatan Tahun 2012
Publisher : STIKES Telogorejo Semarang

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Abstract

ABSTRAK Keputihan merupakan keluarnya cairan dari mulut vagina. Keputihan dapat bersifat fisiologis maupun patologis. Sebanyak 75% wanita mengalami keputihan minimal 1 kali seumur hidup dan 45% mengalami 2 kali atau lebih. Vulva hygiene terkait dengan kejadian keputihan, namun pengetahuan dan keterampilan vulva hygiene belum diketahui hubungannya dengan kejadian keputihan. Penelitian ini bertujuan untuk mengetahui apakah ada hubungan antara pengetahuan dan keterampilan vulva hygiene dengan kejadian keputihan pada ibu rumah tangga di Desa Sawahjoho Warungasem Batang. Desain penelitian ini adalah Crossectional dengan umlah sampel 90 responden dengan tehnik Systematic Sampling. Data dikumpulkan dengan kuesioner dan dianalisis secara analitik dan deskriptif dengan uji korelasi Chi-Square. Hasil penelitian menunjukkan mayoritas responden memiliki pengetahuan baik sebayak 43,3%, keterampilan cukup sebanyak 51,1% dan kejadian keputihan mencapai 38,8%. Hasil uji statistic membuktikan ada hubungan antara pengetahuan (p= 0,000) dan keterampilan vulva hygiene (p=0,000) dengan kejadian keputihan. Wanita usia dewasa disarankan untuk selalu menambah pengetahuan dan keterampilannya untuk mengurangi resiko kejadian keputihan.   Kata kunci: Pengetahuan, Keterampilan, Keputihan
HUBUNGAN ANTARA PENGETAHUAN DAN KETERAMPILAN VULVA HIGIENE DENGAN KEJADIAN KEPUTIHAN PADA IBU RUMAH TANGGA (STUDI DI DESA SAWAHJOHO WARUNGASEM BATANG) Melati, Rika; Jemi Santoso, Eko; -, Sayono
Karya Ilmiah S.1 Ilmu Keperawatan Tahun 2012
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Keputihan merupakan keluarnya cairan dari mulut vagina. Keputihan dapat bersifat fisiologis maupun patologis. Sebanyak 75% wanita mengalami keputihan minimal 1 kali seumur hidup dan 45% mengalami 2 kali atau lebih. Vulva hygiene terkait dengan kejadian keputihan, namun pengetahuan dan keterampilan vulva hygiene belum diketahui hubungannya dengan kejadian keputihan. Penelitian ini bertujuan untuk mengetahui apakah ada hubungan antara pengetahuan dan keterampilan vulva hygiene dengan kejadian keputihan pada ibu rumah tangga di Desa Sawahjoho Warungasem Batang. Desain penelitian ini adalah Crossectional dengan umlah sampel 90 responden dengan tehnik Systematic Sampling. Data dikumpulkan dengan kuesioner dan dianalisis secara analitik dan deskriptif dengan uji korelasi Chi-Square. Hasil penelitian menunjukkan mayoritas responden memiliki pengetahuan baik sebayak 43,3%, keterampilan cukup sebanyak 51,1% dan kejadian keputihan mencapai 38,8%. Hasil uji statistic membuktikan ada hubungan antara pengetahuan (p= 0,000) dan keterampilan vulva hygiene (p=0,000) dengan kejadian keputihan. Wanita usia dewasa disarankan untuk selalu menambah pengetahuan dan keterampilannya untuk mengurangi resiko kejadian keputihan.   Kata kunci: Pengetahuan, Keterampilan, Keputihan
PENAMBATAN MOLEKUL SIANIDIN Ipomoea batatas L. SEBAGAI INHIBITOR HUMAN EPIDERMAL RECEPTOR 2 (HER-2) PADA KANKER PAYUDARA Ayubbi, Muhammad Reza Pahlevy Al; Melati, Rika; Karimah, Umul
Journal of Sustainable Transformation Vol. 1 No. 2 (2023)
Publisher : Universitas Nahdlatul Ulama Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59310/jst.v1i2.14

Abstract

HER-2 (Human Epidermal Receptor 2) is a receptor on the cell surface that affects cell proliferation, this receptor support controls healthy cell growth,divide and repair cells when they are damaged. When HER-2 had overexpressed will not controlled cancer cell division. Overexpressed HER-2 could inhibited with cyanidine compound flavonoid derivatives from Ipomoea batatas L. (purple sweet potato). This study aim to measured potential of Ipomoea batatas L. cyanidin compounds in inhibited overexpressed HER-2 using computational chemistry methods specifically is molecular docking. Stages of molecular docking receptor HER-2 is ligand set up with drew structure cyanidine with Marvin Sketch then optimized by Autodock Tools and Discovery Studio, lapatinib as a comparison ligand downloaded on PubChem website. HER-2 (3PP0) prepared with downloaded on Protein Data Bank website then optimized by Autodock Tools. Molecular Docking validated with docked protein target with native ligand by PyMOL to secured RMSD (root mean square deviation). Protein Targeted HER-2 docked with test ligand cyanidine, lapatinib, and native ligand by Autodock VINA, analysed energy bond and amino acid residue interactions by LigPlot+. Cyanidine had potency inhibitor of receptor HER-2 overexpressed from docked is had bound energy -7.1 ccal/mol up to -8.6 ccal/mol wich is also had amino acid residue interactions Met 801 equal to native ligand
PENGUKURAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL & FRAKSI ETIL ASETAT DAUN JERUK PURUT (Citrus hystrix DC) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Rizky Saputra, Dewa; Melati, Rika; Karimah, Umul
Journal of Sustainable Transformation Vol. 2 No. 01 (2023)
Publisher : Universitas Nahdlatul Ulama Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59310/jst.v2i01.26

Abstract

This study measured the total flavonoid content of 70% ethanol extract and the ethyl acetate fraction of kaffir lime leaves (Citrus hystrix DC). The purpose of this study was to measure the total flavonoid content of the 70% ethanol extract and the ethyl acetate fraction of kaffir lime leaves (Citrus hystrix DC). Extraction of the chemical content of kaffir lime leaves (Citrus hystrix DC) was carried out by maceration and remaceration extraction processes using ethanol and to measure the metabolite compounds. flavonoids in total and separate other metabolites by a fractionation process,). Measurement of total flavonoid content of ethanol extract and ethyl acetate fraction by UV-Vis spectrophotometry. The results showed that the total flavonoid content of kaffir lime leaves (Citrus DChystrix DC) from the ethanol extract contained a total flavonoid content of 14,380 mgQE/g and the ethyl acetate fraction contained a total flavonoid content of 44,287 mgQE/g.
IMPLEMENTATION OF PROBLEM BASED LEARNING AND TEACHING AT THE RIGHT LEVEL (TARL) APPROACH COMBINED WITH GAMES FACTS ABOUT ME AS AN EFFORT TO IMPROVE STUDENTS' HIGHER LEVEL THINKING SKILLS Roidah Affifah, Jihan; Zubaidah, Siti; Melati, Rika
Jurnal Ekonomi, Bisnis dan Pendidikan (JEBP) Vol. 3 No. 7 (2023)
Publisher : Universitas Negeri Malang

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Abstract

The implementation of the Merdeka Curriculum necessitates the development of high-level thinking skills, a crucial aspect of 21st-century competencies. This research aims to enhance students' higher-order thinking skills by applying the Problem-Based Learning (PBL) model in conjunction with the Teaching at the Right Level (TaRL) approach and educational games. The study focused on seventh-grade students at SMP Negeri 16 Malang. Employing a qualitative research design, the case study method was utilized to gain in-depth insights. Data were collected through observations conducted by the researchers and several observers during the learning activities. The findings from the observations indicated a significant improvement in students' higher-order thinking skills following the implementation of the PBL model and TaRL approach. Additionally, integrating educational games proved to be an effective strategy for engaging students and facilitating a deeper understanding of complex concepts. This research underscores the potential of innovative teaching methods to foster critical thinking and enhance educational outcomes in contemporary learning environments.