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All Journal Juke Berkala Ilmu Kesehatan Kulit dan Kelamin Biology, Medicine, & Natural Product Chemistry Majalah Kedokteran Sriwijaya SRIWIJAYA JOURNAL OF MEDICINE Jurnal Pengabdian Masyarakat: Humanity and Medicine
Fifa Argentina
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Relationship of Scabies With Pioderma: As a Risk Factor Yahya, Yulia Farida; Argentina, Fifa; Rusmawardiana, Rusmawardiana
Sriwijaya Journal of Medicine Vol. 1 No. 1 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Scabies is a parasitic infestation of the skin, that is affecting on the low income and crowded community in many tropical countries, especially developing countries such as Indonesia. Scabies infestation increases the incidence of secondary pyoderma include impetigo, folliculitis, cellulitis, ecthyma, abscess. Secondary pyoderma is a skin infection disease mainly caused by group A Streptococcus (GAS) and Staphylococcus aureus (SA). Pyoderma is a risk factor for the glomerulonephritis infection, rheumatic diseases, which significantly increases morbidity and mortality, causing the government burden. The aim of this study is determining the etiology and correlation of pyoderma infection in scabies patient. To determine sosio-demographic included sex, age in pediatric patients in primary schools (SD) in the district of Kertapati Palembang. The study design was cross sectional, and study samples were new scabies patients in the elementary school (age 6-14-year-old) with or without pyoderma. Clinical findings included history, physical examination and diagnostic procedure, which was investigation of skin scraping specimen material (SSB = skin surface biopsy) in confirmation with dermoscopic polar examination (DS) to show Sarcoptes scabiei mites. Microbiological examination with Gram stain identified the etiology of pyoderma. Results of this study shows that there was a significance relationship between scabies infestation and pyoderma in children in elementary school. Staphylococcus aureus dan GAS are the most common caused of pyoderma in pediatric patients with scabies. Conclusion is there is a significant correlation between scabies and pyoderma. There is a need to provide scabies and pyoderma medication at primary care health center as well as counseling for prevention in Palembang area with crowded population periodically.
Peran Antimicrobial peptide (AMP) pada kusta Argentina, Fifa; Rusmawardiana, Rusmawardiana; Andarini, Febrina
Sriwijaya Journal of Medicine Vol. 2 No. 2 (2019): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Antimicrobial peptides (AMP) berfungsi sebagai sistem pertahanan innate tubuh pada banyak organisme. Antimicrobial peptide ini memiliki peran dalam respon sistem imunitas dengan cara menjadi garis depan sistem pertahanan melawan infeksi. Ditemukan ada beberapa AMP pada manusia dan mamalia. Namun pada pembahasan makalah ini akan difokuskan pada cathelicidin (LL-37) dan human β-defensin-1 (HBD-1), HBD-2, HBD-3, yang merupakan AMP paling banyak pada manusia. Peran AMP penting terutama terhadap penyakit infeksi. Pada penelitian terbaru ditemukan berbagai peran AMP terhadap penyakit kusta. Antimicrobial peptides dapat juga mengaktifkan dan mengerahkan sel imun, sehingga mengakibatkan penghancuran mikroba dan/atau mengontrol inflamasi. Antimicrobial peptide berperan dalam membunuh mikobakteri pada lesi kusta dan sehingga dapat dihubungkan dengan bentuk klinis penyakit tersebut, namun mekanisme kerja AMP masih memerlukan penelitian lebih lanjut. Kusta ditandai dengan spektrum klinis luas berdasarkan respon imunitas seluler host. Manifestasi klinis dan klasifikasi kusta berhubungan dengan tipe respon imun yang terjadi. Pola ekspresi dan regulasi AMP spesifik pada setiap tipe sel pada masing-masing organ. Telah banyak penelitian mengenai AMP pada berbagai kondisi kulit. Pada keadaaan infeksi, sangat penting untuk mengaktifkan respon imun guna menarik sel imun lain dan juga mengontrol inflamasi.
Identifikasi Polimorfisme Titik -1082 Promoter Gen IL-10 pada Penderita Kusta Oktariana, Desi; Argentina, Fifa; Lusiana, Evi; Tamzil, Nia Savitri
Sriwijaya Journal of Medicine Vol. 3 No. 1 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Leprosy is a chronic disease caused by Mycobacterium lepraeinfection, which affects skin and nerves, then can result in disability. Interleukin-10 have an important role in the pathogenesis of leprosy. Polymorphism in this gene promoter is thought to affect IL-10 production, which can then influence the process of microbial elimination in the development of leprosy. One of the most common polymorphisms associated with IL-10 is the polymorphism of the -1082 on the gene promoter. The purpose of this study was to identify the polymorphism of the -1082 interleukin-10 gene promoter in leprosy patients treated at RSUP dr. Mohammad Hoesin Palembang. This research is an observational descriptive study with cross sectional design. Polymorphism of -1082 interleukin-10 gene promoter was measured by PCR-RFLP method, electrophoresis, and visualized in UV light. From this study it was found that the frequency distribution of genotype AA was 80%, AG was 14%, and GG was 6%. The frequency distribution of allele A is 87% and allele G is 13%. Wild type genotype is more common in leprosy sufferers (80%).
Management of Infantil Hemangioma Fifa Argentina; Hendra Tarigan Sibero
JUKE Unila Vol 4, No 07 (2014)
Publisher : Fakultas Kedokteran Universitas Lampung

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Abstract

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Skin Microbiota Fifa Argentina; Rusmawardiana Rusmawardiana; Grady Garfendo
Majalah Kedokteran Sriwijaya Vol 52, No 1 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i1.11425

Abstract

The skin is a complex and dynamic ecosystem. It may act as physical barrier to bar the invasion of foreign pathogens while concomitantly providing home to commensals bacteria, fungi and viruses. These microbes were known as microbiota. Over a human’s life span, skin cells, immune cells, and microbiota will integrate to maintain homeostasis of skin’s physiology and immune barrier, both under healthy conditions and also under stresses (infection and wounding). Shifts in the normal microbiota may cause diseases such as atopic dermatitis and psoriasis even though pathophysiology of these conditions is still unknown.
HUBUNGAN PENGETAHUAN, SIKAP, DAN PERILAKU PERAWATAN VAGINA TERHADAP KEJADIAN KEPUTIHAN PATOLOGIS PADA MAHASISWI PROGRAM STUDI PENDIDIKAN DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS SRIWIJAYA Neubrina Raesuky Sukamto; Yulia Farida Yahya; Dwi Handayani; Fifa Argentina; Iche Andriyani Liberty
Majalah Kedokteran Sriwijaya Vol 50, No 4 (2018): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v50i4.8571

Abstract

Keputihan (leukorea, flour albus, vaginal discharge) adalah sekret yang berlebihan dari vagina selain darah haid, dan tidak disebabkan neoplasma atau penyakit sistemik. Keputihan dapat bersifat fisiologis (normal) dan patologis (abnormal).. Pengetahuan dan perawatan yang baik dalam menjaga kebersihan organ reproduksi dapat memelihara kesehatan reproduksi. Kurangnya pengetahuan, sikap, dan perilaku dalam perawatan vagina diyakini berpengaruh terhadap kejadian keputihan patologis. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap, dan perilaku perawatan vagina terhadap kejadian keputihan patologis pada mahasiswi Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sriwijaya.Penelitian ini adalah penelitian analitik observasional dengan pendekatan cross-sectional. Sampel penelitian ini adalah semua mahasiswi Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sriwijaya angkatan 2015-2018.Dari 599 responden, faktor berpengaruh bermakna terhadap terjadinya keputihan patologis adalah pengetahuan (p= 0,044), sikap (p= 0,041) dan perilaku (p= 0,000) sesuai dengan hasil multivariat.pengetahuan, sikap, dan perawatan vagina merupakan faktor yang berpengaruh terhadap kejadian keputihan patologis
Pemberdayaan tenaga kesehatan pada fasilitas kesehatan primer di Kecamatan Sungsang: pengenalan kanker kulit Yahya, Yulia Farida; Toruan, Theresia L; Kurniawati, Yuli; Nopriyati, Nopriyati; Argentina, Fifa; Trilisnawati, Damai; Findrapase, Riri Puspa Putri; Deddy, Deddy; Antonius, Cayadi Sidarta; Saputra, M. Akip Riyan; Fantoni, Odelia Jovita Jusuf; Candra, Nofilia Citra
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 2 No 2 (2021): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V2I2.55

Abstract

Empowering health workers at primary health facilities in Marga Sungsang Village: introduction to skin cancer. Skin cancer is a skin malignant tumor derived from keratinocytes and melanocyte cells, known as keratinocyte carcinoma and cutaneous melanoma, the most common is keratinocyte carcinoma consisting of Basal cell carcinoma(BCC) and Squamous cell carcinoma (SCC) and rarely cutaneous melanoma (MM). The incidence has increased sharply around the world, especially in Palembang. The study in Palembang at RSMH (2017-2019) found that there was an increase of skin cancer is five times compared to previous studies. Generally, skin cancer patients referred to tertiary hospitals are in the advanced stage and accompanied by complications, increasing morbidity and mortality, making therapy difficult. so the cost of hospital care is high and becomes a burden to the state. The problem for health workers in primary health facilities is that knowledge about skin cancer is still low and this knowledge is only obtained during education level. The purpose is to improve and develop the knowledge of primary health care workers by Oncologist and skin surgeon and lecturer in Dermatology and Venereology FK Unsri / RSMH Palembang, about skin cancer and its problems, reducing the incidence and finding new cases of skin cancer, preventing skin cancer an advanced stage in primary health facilities. The counseling in the village of Marga Sungsang, Sungsang sub-district, 27 participants consist of 26 women (96,3%) and 1 male (3,7%) participants, with varied in age, the youngest was 18 years and highest was 44 years old. Education level: SMA as 20 participants (74.0%) and S1 / AMK level as 7 participants (25.9%). The results of the pretest and posttest knowledge showed a 5-fold increase posttest compared to the pretest. The knowledge of skin cancer health workers is still low. Counseling is needed for all health workers and community leaders in the Banyuasin district.
Pelatihan pemeriksaan prevention of disability (POD) kusta pada tenaga Kesehatan dan kader di Kabupaten Prabumulih Nopriyati; Rusmawardiana; Argentina, Fifa; Deddy; Antonius, Cayadi Sidarta; Setiawan, Ivon; Veronica
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 4 No 1 (2023): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V4I1.96

Abstract

Leprosy is a chronic granulomatous infection caused by Mycobacterium leprae. Leprosy infects skin, mucosa and peripheral nerves causing loss of skin sensation with or without skin lesions. Clinical feature of leprosy is highly variable, and can resemble a variety of lesions present in other diseases. Differential diagnosis of skin lesions is so broad that it can lead to misdiagnosis. Based on data from the World Health Organization (WHO) in 2018, it was reported that the number of new cases of leprosy in the world was 210,671 cases, with a new case detection rate of 2.77 per 100,000 population. Indonesia is ranked third in the world as a country with the most new cases of leprosy after India and Brazil. Lack of knowledge of health workers and cadres affects the number of leprosy cases found. This community service activity was carried out with the aim of providing counseling regarding early leprosy examination to health workers and cadres in Prabumulih. The activity was coordinated by Dermatology, Venereology, and Aesthetics Department, Faculty of Medicine, Sriwijaya University, in collaboration with AR Bunda Hospital Prabumulih. At the end of the activity the participants had a better understanding of leprosy and the steps for early leprosy examination. This activity is useful for increasing the knowledge of health workers and cadres about leprosy and how to check for leprosy.
Bakti sosial pemeriksaan, pengobatan skabies dan pendampingan pimpinan dan perangkat di pondok pesantren Kabupaten Prabumulih Rusmawardiana; Nopriyati, Nopriyati; Argentina, Fifa; Deddy, Deddy; Antonius, Cayadi Sidarta; Setiawan, Ivon; Veronica, Veronica
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 4 No 2 (2023): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V4I2.97

Abstract

Scabies is a skin disease caused by infestation and sensitization of Sarcoptes scabiei var. hominis. The prevalence of scabies reaches more than 20% in developing countries and mainly affects children. Scabies is more commonly found in a location with dense population, with high direct or indirect contact, such as in Islamic boarding schools. This counseling and community service activity aims to provide information related to scabies to students and to screen scabies risk factors at Darussalam Prabumulih Islamic Boarding School. The results of the questionnaire screening showed that respondents had a high risk of scabies infestation based on an assessment of the 4 main risk factors. The results of anamnesis and physical examination of 49 students showed that 19 students (38.7%) had scabies infestation and 30 students (61.3%) were free from scabies infestation. This counseling is expected to help reduce the number of scabies infestations in densely populated residential locations, especially in Islamic boarding schools.
Epidemiology of Leprosy in Indonesia: a Retrospective Study Lubis, Ramona Sari; Anum, Qaira; Argentina, Fifa; Menaldi, Sri Linuwih; Gunawan, Hendra; Yuniati, Renni; Mulianto, Nur Rachmat; Siswati, Agnes Sri; Widasmara, Dhelya; Rusyati, Luh Made Mas; Mamuaja, Enricco Hendra; Muchtar, Vitayani; Cita Rosita Sigit Prakoeswa; Agusni, Regitta Indira; Bagus Haryo Kusumaputra; Medhi Denisa Alinda; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.29-35

Abstract

Background: According to WHO data, the number of new cases of leprosy has decreased in 2019. However, Indonesia continues to provide a significant number of cases. According to statistics, India, Brazil, and Indonesia account for 79 percent of all instances. Purpose: This study aims to describe the profile of leprosy patients, and involves all Dermatology and Venereology Academic Hospitals in Indonesia. Methods: This study was a retrospective study of 2461 patients from Dermatology and Venereology Outpatient Clinic at 13 Academic Hospitals in Indonesia between January 2018 and December 2020. Result: Subjects in this study were dominated by males (66.8%) and aged > 14 years (95.3%). The most common type of leprosy was multibacillary (MB) (86.2%), and erythema nodosum leprosum (ENL) was the most leprosy reaction (20.3%). Majority of the subjects experienced disability in the hands (26.6%), in grade 1. Conclusion: Leprosy cases in Indonesia are mostly experienced by adult males. The most common type of leprosy is MB, with ENL being the most common leprosy reaction. Grade 1 disability is the most prevalent, therefore proper education is necessary to keep patients from progressing to grade 2 disability.
Co-Authors Agnes Sri Siswati Andarini, Febrina Andarini, Febrina Antonius, Cayadi Sidarta Anum, Qaira Athiah, Medina Bagus Haryo Kusumaputra Candra, Nofilia Citra Cita Rosita Sigit Prakoeswa Deddy Deddy Deddy Dhelya Widasmara Diba, Sarah Dwi Handayani Evi Lusiana Fantoni, Odelia Jovita Jusuf Fertilita, Soilia Findrapase, Riri Puspa Putri Fitriani Fitriani Grady Garfendo Hendra Tarigan Sibero Iche Andriyani Liberty, Iche Andriyani Jayawarsa, A.A. Ketut Kartowigno, Soenarto Larasati, Veny Lubis, Ramona Sari Luh Made Mas Rusyati M. Yulianto Listiawan Mamuaja, Enricco Hendra Medhi Denisa Alinda, Medhi Denisa Muchtar, Vitayani Mulianto, Nur Rachmat Neubrina Raesuky Sukamto Nopriyati Nopriyati, Nopriyati Oktariana, Desi Rasyid, Riana Sari Puspita Regitta Indira Agusni Renni Yuniati Rusmawardiana Rusmawardiana, Rusmawardiana Saputra, M. Akip Riyan Setiawan, Ivon Sri L. Menaldi Tanta, Yudhi Toruan, Theresia L Trilisnawati, Damai Veronica VERONICA VERONICA Yuli Kurniawati, Yuli Yulia Farida Yahya Zulfadli, Muhammad