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All Journal JURNAL FARMASIMED (JFM) International Journal of Health Sciences Usadha Parapemikir Jurnal Ilmiah Farmasi BOHSEJ (Bhamada Occupational And Health Safety Environment Journal) Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal)
Listina, Osie
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Agriculture, Biological Sciences & Forestry Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Physics Public Health Other

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EFFECTIVENESS OF COMBINATION OF BITTER GOURD (Momordica charantia L.) AND GARLIC (Allium sativum L.) EXTRACT ON MALE WHITE MICE (Mus muscullus) AS APHRODISIAC Alfiraza, Ery Nourika; Listina, Osie; Gautama, Tomy Sugiarto
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1242

Abstract

Aphrodisiac is a material that used to increase libido or sexual desire. The purpose of this study was to determine the effect of aphrodisiac on bitter melon fruit (Momordica charantia L.) and garlic (Allium sativum L.) in male white mice (Mus musculus L.) and at what concentration the combination of bitter melon and garlic had the best aphrodisiac effect. Bitter melon powder and garlic were macerated with 70% ethanol for 4 x 24 hours. In this study, ICC (Introduction, Climbing, Coitus) method was used in 25 male mice divided into 5 groups. Group I as negative control was given aquadest, group II was given a single dose of bitter melon, group III a single dose of garlic, Group IV, and Group V were given a combination of bitter melon extract and garlic with ½ combination 980 mg/kg body weight: 150mg /kg body weight, Group IV, and V were given a combination of bitter melon extract and garlic with 1 combination 1960 mg/kg body weight: 300 mg/kg body weight. Each group was given oral test materials, group I, II, III, IV, and V was given extracts according to the dose for 2 hours. Then those observed and calculated the number of Introduction, Climbing, and Coitus. The results showed that the combination of bitter melon extract and garlic group V (1960 mg/kg body weight: 300 mg/kg body weight) had the best aphrodisiac activity compared to other extract combination activities, and all extract combinations showed significantly different aphrodisiac effects.
Uji Efektivitas Antiinflamasi Ekstrak Etanol dan Fraksi Daun Ciplukan (Physalis angulata L.) Terhadap Mencit Putih Jantan (Mus musculus) Listina, Osie
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.8757

Abstract

Inflammation is a local protective response caused by tissue damage. Antiinflammatory drugs steroids and non steroids have many side effects so that there are many antiinflammatory development derived from natural materials, especially in plants.This study aimed to determine the anti-inflammatory effects of ethanol extract, N-hexane fraction and ethyl acetate fraction with doses of 600mg/kgBW, 1200mg/kgBW and 1800mg/kgBW. The method used was the production of udem induced with 1% carragenin subplantar. The study was conducted by administering carragenine as an inflammatory mediator on the feet of mice, then administering orally suspension Ethanol extract, N-hexane fraction and ethyl acetate fraction. Sodium CMC was as a negative control and diclofenac sodium was as a positive control. Measurements were taken every 30 minutes for 6 hours after induction of 1% carragenin. Based on the result of research, ethanol extract with dose of 600mg/kgBB had anti-inflammatory power of 48,43%, N-hexane fraction with dose 1200mg/kgBB had antiinflammatory power of 33,21% and ethyl acetate fraction with dose 1800mg/kgBB had anti inflammatory power equal to 50,08% and the most effective dose of anti inflammatory power of ethanol extract and ciplukan leaf fractionation at fraction of ethyl acetate 1800mg / kgBB with anti inflammatory value of 50,08%.
The Influence of Fast Method Health Education on Nurses' Knowledge in Early Detection of Stroke Disease at Labuang Baji Regional Hospital, Makassar City Noviar, Rizki Andita; Belangi, Siska Putri; Suminar, Saka; Sallo, Andi Kamal M.; Listina, Osie; Fahamsya, Arifina
International Journal of Health Sciences Vol. 2 No. 3 (2024): International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v2i3.443

Abstract

Stroke is a medical emergency because it is time-related and requires fast, precise and careful treatment. Optimal management can prevent death and permanent disability. One strategy to increase awareness of stroke attacks can be done through education in the form of audiovisual methods which contain information about early detection of stroke. The aim of this research is to find out the influence of FAST method education on nurses' knowledge in early detection of stroke. This research is quantitative research using pre-experimental design. The type of test used is the Wilcoxon test with the research results being the pre test. The conclusion of this research is. There is an influence of FAST method counseling on nurses' knowledge in early detection of stroke with a value of P = 0.000. The results of this research can add information and input for health workers to improve the quality of health services in preventing strokes.
The Relationship between Cariogenic Food Consumption and the Incidence of Dental Caries in Grade 5 Children of Public Elementary School 10 in Kampung Baru Prastyo, Eko; Belangi, Siska Putri; Sahalessy, Yona; Listina, Osie; Yulis, Dian Meiliani; Utari, Utari
International Journal of Health Sciences Vol. 2 No. 3 (2024): International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v2i3.448

Abstract

Cariogenic foods are foods that contain lots of carbohydrates, are sticky and break down easily in the mouth. Dental caries is damage to hard tooth tissue caused by acids contained in carbohydrates through microorganisms contained in saliva. The aim of this study was to determine the relationship between consumption of cariogenic foods and the incidence of dental caries in grade 5 children at SD Negeri 10 Kampung Baru r. The type of research used is analytical descriptive research using a cross sectional design. The population in this study was 95 people and the sampling technique used Consecutive Sampling technique, the total sample was 77 respondents. Data was collected using a questionnaire, the collected data was then processed and analyzed using Microsoft Excel and the SPSS program. Data analysis includes univariate analysis by looking for frequency distributions, bivariate analysis with the Chi-Square test (α=0.05) to determine the relationship between variables. The research results show that based on the results of the Chi-Square test, the value obtained is p=0.003. The conclusion of this research is that there is a relationship between the consumption of cariogenic foods and the incidence of dental caries in grade 5 children at SD Negeri 10 Kampung Baru.
Relationship Between Erythrocyte Index Values And Serum Ferritin Levels In Anemia At The Pathological Laboratory Listina, Osie
International Journal of Health Sciences Vol. 2 No. 3 (2024): International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v2i3.463

Abstract

Anemia is a medical condition characterized by low levels of hemoglobin in the blood, which can lead to symptoms such as fatigue, dizziness, pale skin, and the body's inability to transport oxygen efficiently enough. Anemia can be caused by various factors, including iron deficiency, vitamin B12 deficiency, genetic disorders, and chronic diseases. Recent research and data are also presented to provide a better understanding of the prevalence and impact of anemia in the global population. This study was conducted on 94 people suffering from anemia who were treated at Dr. Tadjuddin Chalid Hospital based on patient medical records for the period January 2022 - June 2023. This study is a retrospective observational descriptive study on anemia patients from medical records treated at Dr. Tadjuddin Chalid Hospital. Data analysis was processed using SPSS software. The results of this study indicate the distribution of anemia patients treated at Dr. Tadjuddin Chalid Hospital Makassar for the period January 2022 - June 2023, namely. Of the total sample of 94 people who suffered from anemia, there were 47 male patients (50%) and 47 female patients (50%). The results and conclusions that were obtained in patients with iron deficiency anemia with low MCV and MCH erythrocyte levels, while the MCHC erythrocyte levels cannot be used as a measure of someone affected by iron deficiency anemia and low serum ferritin levels are a strong sign of iron deficiency anemia.
EVALUASI PERESEPAN OBAT ANTIDIABETIK ORAL PASIEN PROLANIS BERDASARKAN INDIKATOR WHO di PUSKESMAS KALADAWA Listina, Osie
Parapemikir : Jurnal Ilmiah Farmasi Vol 13, No 3 (2024): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v13i3.6655

Abstract

Diabetes mellitus merupakan suatu penyakit menahun yang ditandai dengan terjadinya peningkatan kadar gula darah yang melebihi batas normal karena adanya kelainan sekeresi insulin. Tujuan penelitian ini untuk mengetahui evaluasi peresepan obat antidiabetik oral berdasarkan indikator WHO pada pasien prolanis rawat jalan di Puskesmas Kaladawa tahun 2021. Metode penelitian ini berdasarkan dekskriptif non analitik. Populasi yang digunakan yaitu data sekunder berupa resep dan rekam medis pasien prolanis hipertensi, diabetes mellitus dan komplikasi hipertensi dan diabetes mellitus pada periode tahun 2021. Pengambilan sampel menggunakan proporsive sampling yang ditentukan berdasarkan rumus estimasi proporsi mutlak sebanyak 56 resep. Hasil yang diperoleh bahwa evaluasi pola peresepan berdasarkan indikator WHO rata-rata item obat per lembar resep yaitu 3,5 obat, persentase peresepan obat yang diresepkan berdasarkan obat generik 96,98%, dan persentase peresepan obat yang diresepkan sesuai dengan Fornas sebanyak 98,49%. Berdasarkan hasil evaluasi pola peresepan indikator peresepan (WHO) pada persentase peresepan obat yang sesuai dengan Fornas belum sesuai dengan nilai estimasi WHO.
EVALUASI PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI DI INDONESIA: A LITERATURE REVIEW Listina, Osie; Alfiraza, Ery Nourika; Fahamsya, Arifina; Lestari, Fitri
Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal) Vol 16 No 1 (2025)
Publisher : UNIVERSITAS BHAMADA SLAWI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/jik.v16i1.779

Abstract

Hipertensi atau tekanan darah tinggi merupakan suatu kondisi yang ditandai ketika seseorang mengalami kenaikan tekanan darah sistolik ≥140 mmHg dan tekanan darah diastolik ≥90 mmHg. Evaluasi penggunaan obat bertujuan untuk memastikan penggunaan obat antihipertensi secara rasional,meningkatkan ketetapan dan keamanan penggunaan obat penderita hipertensi. Penelitian ini bertujuan untuk mengetahui penggunaan obat antihipertensi pada pasien hipertensi dan evaluasi penggunaan obat antihipertensi pada pasien hipertensi berdasarkan rasionalitas di Indonesia. Literatur yang digunakan dalam penelitian ini berasal dari jurnal-jurnal yang telah diterbitkan secara nasional. Literatur yang digunakan adalah literatur dari tahun 2016 hingga 2021 yang dapat diakses bentuk full text dalam format PDF. Untuk mendapatkan jurnal tersebut, peneliti menggunakan search engine seperti Google Scholar dan dengan kata kunci: evaluasi; rasionalitas; penggunaan obat antihipertensi; pasien hipertensi. Hasil studi literatur sebanyak 7 jurnal menunjukkanbahwa penggunaan obat antihipertensi di Indonesia yang paling banyak digunakan golongan Calcium Channel Blocker (CCB), yaitu amlodipin, Angiotensin Converting Enzyme Inhibitor (ACEI) yaitu captopril, golongan Angiotensin Receptor Blocker (ARB) yaitu candesartan dan golongan diuretic loop yaitu furosemide. Pada evaluasi rasionalitas terhadap penggunaan obat antihipertensi di Indonesia sudah sesuai dengan kriteria tepat indikasi, tepat pasien, tepat obat dan tepat dosis dari 7 jurnal dengan rentang rasionalitasnya 64,6%- 100%.
Analisis Laboratory Safety dan Simptom Klinis Penyakit Akibat Kerja di Laboratorium Fakultas Ilmu Kesehatan Universitas Bhamada Slawi Kabupaten Tegal Listina, osie; Prabowo, Aditya Yulindra Agung; Cahyanta, Agung Nur
Bhamada Occupational Health and Safety Environment Journal Vol 3 No 1 (2025): Juni
Publisher : LPPM Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/bohsej.v3i1.804

Abstract

Peralatan dan fasilitas yang ada di laboratorium yang kurang memadai sangat memungkinkan potensi bahaya dan pelanggaran terhadap prosedur Keselamatan dan Kesehatan Kerja (K3) di laboratorium. Selain itu dampak lain yang terjadi adalah munculnya Penyakit Akibat Kerja (PAK). Untuk menghindari atau meminimalisir terjadinya kecelakaan kerja perlu dilakukan tindakan pencegahan yaitu melalui identifikasi potensi bahaya yang dapat timbul dari suatu aktivitas. Penelitian ini bertujuan untuk menganalisis keamanan laboratorium dan keluhan simptom klinis PAK pada laboran yang bekerja di Laboratorium Kesehatan Fakultas Ilmu Kesehatan Universitas Bhamada Slawi. Metode penelitian ini dengan menggunakan pendekatan deskriptif kualitatif yang didukung oleh data-data kuantitatif melalui hasil kuesioner yang melibatkan seluruh laboran. Berdasarkan hasil kuesioner menyatakan bahwa sejumlah 90% laboran sudah mengetahui kebijakan kesehatan dan keselamatan kerja namun hanya 50% laboran yang sudah mendapatkan fasilitas pelatihan K3 dan perlengkapan keamanan kerja, dan sejumlah 60% laboran menyatakan belum terlindungi dari risiko keselamatan dan kesehatan kerja di laboratorium. Keluhan simptom klinis PAK yang dirasakan laboran diantaranya rasa gatal dan panas ketika terpapar zat kimia, diare, sesak napas, pusing, memar karena gigitan hewan uji. Hasil penelitian ini menegaskan perlunya meningkatkan protokol keselamatan laboratorium serta penyediaan pelatihan dan perlengkapan K3 yang memadai pada seluruh laboran.
Co-Authors Agung Nur Cahyanta, Agung Nur Alfiraza, Ery Nourika Andi Kamal M. Sallo Belangi, Siska Putri Eko Prastyo Fahamsya, Arifina Fitri Lestari, Fitri Gautama, Tomy Sugiarto Prabowo, Aditya Yulindra Agung Rizki Andita Noviar Sahalessy, Yona Suminar, Saka Utari Utari Yulis, Dian Meiliani