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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences International Journal of Social Learning (IJSL)
Hanafi , Muhammad
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Agriculture, Biological Sciences & Forestry Arts Education Environmental Science Social Sciences Other

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The Leaf Extract of Dysoxylum parasiticum (Osbeck) Kosterm. Contains Anti-oxidant and α-Glucosidase Inhibitor Activities: Leaf Extract of Dysoxylum parasiticum (Osbeck) Kosterm. Wibawa, I Putu Agus Hendra; Hanafi , Muhammad; Butardo Jr , Vito M.; Mahon, Peter J.
Journal of Tropical Life Science Vol. 14 No. 2 (2024)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.14.02.19

Abstract

The medicinal plant Dysoxylum parasiticum (Osbeck) Kosterm. (Meliaceae) is na- tive to Indonesia, but its bioactive potential has been little explored. This study de- termined the phenolic content, antioxidant, and antidiabetic activities of D. parasiti- cum leaf extracts. Dried, powdered leaves were sequentially extracted with hexane, ethyl acetate and methanol. Total phenolic and flavonoid contents were quantified by colorimetric assays. The ethyl acetate extract had the highest phenolic content at 21.54 mg gallic acid equivalents/g dry weight. Antioxidant capacity was evaluated by DPPH radical scavenging assay, while antidiabetic activity was assessed as inhi- bition of α-glucosidase enzyme. The ethyl acetate extract showed potent antioxidant (IC50 30.72 μg/mL) and α-glucosidase inhibitory (IC50 16.32 μg/mL) activities compared to standard controls. Putative bioactive components were identified by LC-MS/MS, including stylosin, capillartemisin A, 19β-glucosyl-14-deoxy-11,12- didehydroandrographoside, daturametelin H, stigmastan-3,6-dione, 2α,3β,4α-trihy- droxy nortropane and arnebinone. The traditional use of D. parasiticum is validated by its antioxidant and antidiabetic potential, which is associated with its phenolic content.
The Leaf Extract of Dysoxylum parasiticum (Osbeck) Kosterm. Contains Anti-oxidant and α-Glucosidase Inhibitor Activities: Leaf Extract of Dysoxylum parasiticum (Osbeck) Kosterm. Wibawa, I Putu Agus Hendra; Hanafi , Muhammad; Butardo Jr , Vito M.; Mahon, Peter J.
Journal of Tropical Life Science Vol. 14 No. 2 (2024)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.14.02.19

Abstract

The medicinal plant Dysoxylum parasiticum (Osbeck) Kosterm. (Meliaceae) is na- tive to Indonesia, but its bioactive potential has been little explored. This study de- termined the phenolic content, antioxidant, and antidiabetic activities of D. parasiti- cum leaf extracts. Dried, powdered leaves were sequentially extracted with hexane, ethyl acetate and methanol. Total phenolic and flavonoid contents were quantified by colorimetric assays. The ethyl acetate extract had the highest phenolic content at 21.54 mg gallic acid equivalents/g dry weight. Antioxidant capacity was evaluated by DPPH radical scavenging assay, while antidiabetic activity was assessed as inhi- bition of α-glucosidase enzyme. The ethyl acetate extract showed potent antioxidant (IC50 30.72 μg/mL) and α-glucosidase inhibitory (IC50 16.32 μg/mL) activities compared to standard controls. Putative bioactive components were identified by LC-MS/MS, including stylosin, capillartemisin A, 19β-glucosyl-14-deoxy-11,12- didehydroandrographoside, daturametelin H, stigmastan-3,6-dione, 2α,3β,4α-trihy- droxy nortropane and arnebinone. The traditional use of D. parasiticum is validated by its antioxidant and antidiabetic potential, which is associated with its phenolic content.
Development of a Value-Clarification-Technique Learning Model Oriented toward Digital Technology Literacy to Foster National Values Kadir, Abdul; Arisa, Arisa; Hanafi , Muhammad; Sadapotto , Andi; Muthmainnah, Muthmainnah; Kadir, M. Fachmy Achdan; Cardoso, Luis; Korten, Christopher; AlSaghbini, Hisham
International Journal of Social Learning (IJSL) Vol. 5 No. 3 (2025): August
Publisher : Indonesian Journal Publisher in cooperation with Indonesian Social Studies Association (APRIPSI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijsl.v5i3.367

Abstract

This research aimed to: 1) innovate learning models using the Value Clarification Technique (VCT) oriented toward improving students’ digital literacy to foster national values at State Junior High School/SMPN 4 Sengkang, and 2) identify the problems in implementing this innovative learning model to promote digital literacy and national values at State Junior High School/SMPN 4 Sengkang. This study was a research and development study that used the Design-Based Research (DBR) approach. The approach included problem identification and analysis, solution design, iterative cycles of testing and refinement, and reflection to produce design principles and implementation guidelines. Data was collected through observation, interviews, documentation, and questionnaires. The data analysis used an interactive model, including data collection, reduction, presentation, and conclusion. The research showed that the innovative learning model based on the Value Clarification Technique successfully improved students’ digital literacy and fostered national values. However, obstacles in implementing this innovative learning model, including inadequate student facilities for online learning at home, affected students’ participation in online learning. In addition, the teachers, especially in group one, tended to focus only on sharing materials and assignments during online learning, which could make students feel bored.
Co-Authors Abdul Kadir AlSaghbini, Hisham Arisa, Arisa Butardo Jr , Vito M. Cardoso, Luis I Putu Agus Hendra Wibawa Kadir, M. Fachmy Achdan Korten, Christopher Mahon, Peter J. Muthmainnah Muthmainnah Sadapotto , Andi