Article Per Year (5 Year)
p-Index From 2020 - 2025
0.562
P-Index
This Author published in this journals
All Journal Faletehan Health Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Indrasari, Yulia Nadar
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Penguatan Manajemen Laboratorium dalam Menurunkan Morbiditas dan Mortalitas Hepatitis B Putri, Aditea Etawati; Hernaningsih, Yetti; Wardhani, Puspa; Rini, Diah Puspita; Indrasari, Yulia Nadar; Ramadhan, Nanda Aulya
Faletehan Health Journal Vol 12 No 01 (2025): Faletehan Health Journal, Maret 2025
Publisher : Universitas Faletehan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hepatitis B virus (HBV) infection is one of the threats in the medical world and requires guaranteed and valid laboratory analysis procedures, one of which is through the quality control (QC) mechanism. As part of laboratory management, QC has an impact on the validity of laboratory analysis results, especially related to HBV infection. The purpose of this study was to determine the level of knowledge of medical analysts before and after laboratory management training. The research method used comparative paired test analysis to obtain the significance and binary logistic regression to determine the most influential questions on the test. The results showed a significant increase in medical analyst knowledge after being given laboratory management material. Supported by a p value = 1.000 from the Hosmer and Lemeshow test and an overall prediction of 95.5% (positive: 92.0% and negative 97.6%), this training was very good in terms of goodness-of-fit and accurate. Material related to immunochromatography (ICT) method is an influential factor based on the analysis of test results. Medical analyst training, especially related to laboratory management in the context of HBV management, has a significant impact and can be continued and developed.
Comparative Analysis of Erythrocyte, Leukocyte, and Platelet Indices through Examinations using Sysmex XN-3000 and Yumizen H2500 in Clinical Practice Wardani, Yuniar Putri; Indrasari, Yulia Nadar; Amrita, Putu Niken Ayu; Fuadi, Muhamad Robi'ul
Current Internal Medicine Research and Practice Surabaya Journal Vol. 6 No. 1 (2025): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v6i1.65391

Abstract

Introduction: Examining erythrocyte, leukocyte, and platelet indices is critical for diagnosis, disease management, therapy selection, and monitoring. It is imperative to evaluate the hematology analyzer used for a complete blood examination, as each device possesses distinct specifications, methods, and technologies. This study aimed to compare complete blood count parameters, specifically the erythrocyte, leukocyte, and platelet indices, using Sysmex XN-3000 and Yumizen H2500. Methods: This cross-sectional study used blood samples from adult outpatients aged >18 years at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Samples were collected using purposive sampling, resulting in 100 blood specimens for complete blood count analysis. The examined variables included erythrocyte, leukocyte, and platelet indices, which were compared across two different instruments, i.e., Sysmex XN-3000 and Yumizen H2500. The data were analyzed using either the Spearman or Pearson correlation test (p<0.05). The Bland-Altman plotting was employed to assess the differences between variables, with a minimum of five agreed-upon outliers. Results: Significant correlations were observed across all parameters, except for the mean corpuscular hemoglobin concentration (MCHC), which showed limited agreement in the Bland-Altman analysis. The Pearson and Spearman analyses revealed a significant correlation in the parameters of erythrocytes (0.00), leukocytes (0.00), and platelets (0.00). The Bland-Altman plot indicated seven outliers in the average MCHC values from the two analyzers, demonstrating insufficient agreement. Conclusion: There is significant agreement and correlation in the erythrocyte, leukocyte, and platelet indices from both analyzers. This finding affirms the compatibility of both instruments for clinical use, with caution advised when interpreting MCHC values.   Highlights: 1. This study evaluated the validity of different hematology analyzers for complete blood count examinations in medical laboratories, a topic that has rarely been discussed in detail. 2. The results of this study are expected to contribute to the quality improvement of medical laboratory technologies in Indonesia.
Correlation between IL-1beta and IL-18 Levels with Dengue Virus Infection Severity Sari, Arabella Vonia; Aryati, Aryati; Budhy, Theresia Indah; Ma`ruf, Anwar; Husada, Dominicus; Palupi, Retno; Sunari, I Gusti Agung Ayu Eka Putri; Indrasari, Yulia Nadar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 3 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i3.2682

Abstract

Activated monocytes/macrophages and T lymphocytes that generate a cytokine storm are thought to play a critical role in the development of dengue. Cytokine storms, characterized by the excessive production of proinflammatory cytokines, can result in cellular dysfunction and organ failure, often contributing to the severity of dengue in affected patients. Interleukin-18 (IL-18), like IL-1beta, is a proinflammatory cytokine released during inflammation triggered by inflammasome activation. Increased IL-1beta and IL-18 during dengue virus infection (DVI) are known to worsen the host's vascular permeability, increasing hemostasis disorders and potentially, all of which are important elements in the pathophysiology of dengue fever. This study investigates the association between IL-1beta levels, IL-18 levels, age, dengue virus serotype, and the severity of dengue virus infection, aiming to understand how these factors interact and influence disease outcomes. This study is an observational cross-sectional design from 59 DVI patients in Dr. Soetomo General Hospital, Surabaya with positive dengue PCR results. Both IL-1beta and IL-18 levels reveal no significant relationship with the patient's age, infection status, and dengue virus serotype. A weak negative significant relationship between IL-1beta levels and the severity of DVI, indicating an inverse relationship between IL-1beta levels and the severity. Further studies are required to investigate the function of these cytokines in severe dengue.
Co-Authors Amrita, Putu Niken Ayu Aryati Aryati Diah Puspitarini Dominicus Husada Fuadi, Muhamad Robi'ul Ma`ruf, Anwar Nanda Aulya Ramadhan Putri, Aditea Etawati Retno Palupi Sari, Arabella Vonia Sunari, I Gusti Agung Ayu Eka Putri Theresia Indah Budhy Sulisetyawati Wardani, Yuniar Putri Wardhani, Puspa Yetti Hernaningsih