The official category is "Synthetic Opioids other than Methadone (primarily fentanyl) ICD-10 code (T40.4)" However, this category is dominated by fentanyl related overdoses.
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Rate of overdose deaths involving fentanyl in the U.S. 1999-2023, by gender
Since 2014, fentanyl-related death rates in the United States increased for both genders until 2022, when it reached a peak. In 2023, there were around 32 overdose deaths involving fentanyl among men in the United States per 100,000 population. However, the rate for men was almost triple than that for women.
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NIDA. (January 16, 2025). Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023, by gender (per 100,000 population) [Graph]. In Statista. Retrieved May 08, 2026, from https://www.statista.com/statistics/1018673/fentanyl-overdose-death-rate-us-by-gender/
NIDA. "Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023, by gender (per 100,000 population)." Chart. January 16, 2025. Statista. Accessed May 08, 2026. https://www.statista.com/statistics/1018673/fentanyl-overdose-death-rate-us-by-gender/
NIDA. (2025). Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023, by gender (per 100,000 population). Statista. Statista Inc.. Accessed: May 08, 2026. https://www.statista.com/statistics/1018673/fentanyl-overdose-death-rate-us-by-gender/
NIDA. "Rate of Drug Overdose Deaths Involving Fentanyl in The U.S. from 1999 to 2023, by Gender (per 100,000 Population)." Statista, Statista Inc., 16 Jan 2025, https://www.statista.com/statistics/1018673/fentanyl-overdose-death-rate-us-by-gender/
NIDA, Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023, by gender (per 100,000 population) Statista, https://www.statista.com/statistics/1018673/fentanyl-overdose-death-rate-us-by-gender/ (last visited May 08, 2026)
Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023, by gender (per 100,000 population) [Graph], NIDA, January 16, 2025. [Online]. Available: https://www.statista.com/statistics/1018673/fentanyl-overdose-death-rate-us-by-gender/
