Yash GuptaORCID icon for 0000-0003-3002-1315

Pennsylvania State University United States of America

Dr. Yash Gupta is a biomedical scientist specializing in parasitology and infectious disease therapeutics. His research has significantly advanced the understanding of malaria pathogenesis and drug discovery. Dr. Gupta has identified novel antimalarial compounds such as Calxinin, a multistage inhibitor that disrupts Plasmodium falciparum calcium homeostasis, and has contributed to the development of HDAC and GAPDH-targeting therapeutics. His work integrates in silico modeling with in vitro and in vivo validation, resulting in high-impact publications and patents. With over 35 peer-reviewed articles and editorial roles in leading journals, Dr. Gupta’s contributions are internationally recognized. He has collaborated across institutions, including the Mayo Clinic and Penn State, and his discoveries are being translated into clinical applications through biotech partnerships.

Yash Gupta

1books edited

1chapters authored

Latest work with IntechOpen by Yash Gupta

Breaking the Cycle of Malaria - Molecular Innovations, Diagnostics, and Integrated Control Strategies presents a comprehensive overview of the evolving landscape of malaria research and control. This edited volume examines the convergence of molecular biology, computational tools, and public health strategies in the global effort to combat malaria. It highlights the importance of molecular diagnostics in detecting asymptomatic and submicroscopic infections, the role of artificial intelligence and machine learning in drug discovery, and the promise of genetically modified vectors in disease control and management. The book also addresses integrated service delivery, vaccine development, and the challenges posed by drug and insecticide resistance, climate change, and global health security. Designed for researchers, clinicians, and public health professionals, this volume offers a multidisciplinary perspective that bridges laboratory science with field implementation. Its strength lies in its ability to synthesize cutting-edge innovations with practical strategies, making it a valuable resource for shaping future directions in malaria elimination.

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