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Drugs And Addiction

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lightbulbAbout this topic
Drugs and addiction is the study of the physiological, psychological, and social aspects of substance use, dependence, and addiction. It encompasses the mechanisms of drug action, the impact of substances on behavior and health, and the societal implications of drug use and addiction, including prevention, treatment, and policy issues.
lightbulbAbout this topic
Drugs and addiction is the study of the physiological, psychological, and social aspects of substance use, dependence, and addiction. It encompasses the mechanisms of drug action, the impact of substances on behavior and health, and the societal implications of drug use and addiction, including prevention, treatment, and policy issues.

Key research themes

1. How do neurobiological and neurogenetic mechanisms underpin addiction as a brain disorder?

This research area investigates the biological basis of addiction, exploring changes in brain structure, function, and genetics that characterize addiction as a chronic neuropsychiatric disorder. It matters because establishing addiction as a brain disorder informs treatment approaches, reduces moral stigma, and supports pharmacological and behavioral interventions targeting brain dysfunctions.

Key finding: The authors synthesize extensive peer-reviewed evidence supporting the Reward Deficiency Syndrome (RDS) model, establishing hypodopaminergia as a common neurogenetic mechanism underlying both substance and behavioral... Read more
Key finding: Ainslie presents a marketplace model of addiction where decision-making arises from competing reward valuations processed across distributed brain circuits rather than a single ‘self’. The paradox of addicts choosing what... Read more
Key finding: While predominantly focusing on environmental influences, this study highlights neurobiological distinctions by demonstrating differential vulnerability and neurochemical actions between cocaine and heroin addiction. It... Read more

2. How do environmental and psychosocial factors contribute to the development and persistence of drug addiction?

This research theme examines how external factors—including social context, environment, early life experiences, and cognitive appraisals—influence addiction trajectories. Understanding these contributions is critical for designing effective prevention, intervention, and recovery strategies that address more than neurobiology, highlighting the complex interaction between environment and brain processes in addiction.

Key finding: The paper presents original data indicating that distinct environmental settings influence heroin and cocaine use differently in addicts, underscoring substance-specific environmental interactions. It shows that environmental... Read more
Key finding: Though a philosophical text, this work emphasizes the enduring importance of personal choice and resilience against external pressures. It provides actionable insights into the development of willpower, encouraging strategies... Read more
Key finding: Through semi-structured interviews with addicts, this study reveals that the initial strong pleasure-seeking motivation in addiction often transitions to ambivalence or resentment due to the diminishing positive effects and... Read more
Key finding: This review identifies three dynamic pathways—cognitive, motivational, and behavioral—that mediate insensitivity to the negative consequences of drug use. It evidences how environmental cues and social context interact with... Read more
Key finding: While focused on bipolar disorder, this study identifies perinatal complications, social support levels, and psychosocial stressors—factors overlapping with substance use risks—as significant in symptom severity. The findings... Read more

3. What innovative conceptual frameworks expand our understanding of addiction beyond traditional disease models?

This theme explores alternative understandings of addiction as embodied experience, chemical interactivity, socio-political phenomenon, and self-programmed environmental patterning. Such approaches complement neurobiological perspectives by incorporating phenomenological, sociocultural, and environmental dimensions relevant to treatment, policy, and recovery, advancing a more holistic understanding of addiction.

Key finding: Applying phenomenology, this paper critiques brain-centered disease models by distinguishing between the biological (disease) and lived (illness) body dimensions of addiction. It argues that addressing addiction solely... Read more
Key finding: Utilizing body-mapping workshops with people in recovery, this sociological study reconceptualizes drug users and bodies as chemically entangled entities. It challenges biomedical addiction narratives by foregrounding how... Read more
Key finding: This theoretical paper proposes a novel model where craving arises from subconscious reactivation of multisensory environmental patterns encoded during psychoactive substance-induced altered states. It conceptualizes the... Read more
Key finding: This pharmacological review challenges the simplistic notion that heroin acts merely as a pro-drug for morphine by demonstrating that heroin and its active metabolites (6-MAM, morphine, and morphine-6-glucuronide) produce... Read more
Key finding: This critique of the chronic, relapsing brain disease (CRBD) model emphasizes that addiction is a biopsychosocial phenomenon embedded in social and political contexts. While acknowledging neural adaptations, it highlights... Read more

All papers in Drugs And Addiction

Current cognitive-motivational addiction theories propose that prioritizing appetitive, reward-related information (attentional bias) plays a vital role in substance abuse behavior. Previous cross-sectional research has shown that... more
Previous findings indicate a relation between mindfulness and control of alcohol use. • We examined whether action identification (AI) of alcohol use explains this relation. • Results showed that more mindful individuals reported greater... more
Addiction is a craved feeling that originates within a person regarding a certain object. It encompasses behavioural and cognitive characteristics of the individual. The addict is always willing to sacrifice, invest anything to be... more
As publicações do Ipea estão disponíveis para download gratuito nos formatos PDF (todas) e EPUB (livros e periódicos). Acesse: http://www.ipea.gov.br/portal/publicacoes As opiniões emitidas nesta publicação são de exclusiva e inteira... more
IntroductionThe ongoing opioid overdose crisis, which has killed over 30,000 people in Canada since 2016, is driven by the volatility of an unregulated opioid drug supply comprised primarily of fentanyl. The Canadian government has... more
Background: In countries experiencing elevated rates of adolescent methamphetamine-related problems, addiction-treatment records have served as a sentinel source of data for understanding the scope and spread of methamphetamine use. In an... more
Monteiro defende que o desenho de políticas públicas racionais, baseadas em avaliações consistentes do que funciona ou não funciona, é o caminho para a melhora dos serviços públicos no Brasil -exigida nas ruas nas manifestações de junho.... more
Kush is killing our youth. It is a mixture that combines synthetic opioids, cannabinoids, and even human bones shaved off from some bodies. It is cheap. It is lethal. And it is everywhere. Families in Susan's Bay, Aberdeen, in Waterloo... more
This chapter reviews the literature on substance abuse and prevention efforts in Native communities. The first section describes demographic characteristics of America's indigenous people, including tribal and government definitions,... more
France Info public radio reviewed a new book by Matthieu Verboud and Christophe Bouquet titled Narcotrafic, le poison de l’Europe, or Narcotraffic, the Poison in Europe. While youngsters hooked into drug trafficking increasingly kill... more
more inclined to go away and think about it. Introverts' in-session speech may be less predictive of outcome, at least in an initial session. On the other hand, one might predict that commitment language coming from an introvert would... more
RÉSUMÉ: L’automédication est un traitement pharmaceutique par un patient de sa propre initiative sans prescription médicale. Le but de cette étude était de déterminer la prévalence de l’automédication chez des patients devant subir un... more
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open) Markmið endurhæfingar á geðsviði er að hjálpa þeim sem hafa átt við langvarandi og alvarlega geðsjúkdóma að stríða að ná betri... more
This paper compares the security paradigms for combating terrorism, drugs and irregular migration and argues that while these have largely failed on their own terms, they have also proven rather successful for the actors shaping them.... more
Introduction: The term “adolescent” is an adjective describing a young person in the process of developing from a child into an adult. It is derived from the Latin verb “adolescere” which means “to grow up.” Alcohol is the world’s... more
Narratives and frames have shaped the overdose crisis since its early stages. Efforts to control knowledge about the role of opioids in chronic pain have influenced clinical guidelines and prescribing behaviour. Dominant narratives shape... more
The research concerning intellectual functioning in addict populations has not addressed basic questions concerning why and how intelligence quotients (IQ) might be related to drug addiction. A study was undertaken to estimate... more
Background. Alcohol dependence is unequally distributed across gender (1/3 women versus 2/3 men), though the percentage of women with alcohol dependence seems to be growing. Little is known whether alcohol affects men and women... more
A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATES STUDIES, AHMADU BELLO UNIVERSITY, ZARIA, IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF MASTER DEGREE IN LAW DEPARTMENT OF ISLAMIC LAW, FACULTY OF LAW, AHMADU BELLO... more
This article is about a case study of a pornography addict who is still in the process of selfrehabilitation. Pornography is a bad and unacceptable act because it is not only prohibited in terms of moral ethics but also in religion... more
RESUMO PURPOSE: Abdominal pain of uncertain etiology is the commonest reason for surgical admission. In this report, we retrospectively evaluate the effect of a laparoscopic approach in the diagnosis and treatment of acute abdominal pain... more
"Amaneció un muerto”. Ésta es la expresión que emplean los habitantes de Badiraguato para comunicar que alguien fue asesinado. Se trata de una formulación extraña que espera al día siguiente para hacer amanecer al muerto, dándole un rol... more
Buku ini merupakan kajian komprehensif mengenai Indonesia Emas 2045, menyatukan inovasi ekonomi, riset tanaman terapeutik, dan kemandirian nasional dalam sektor kesehatan, hukum, teknologi, dan budaya. Fokus utama adalah pengembangan... more
ABSTRAK: Kajian ini bertujuan untuk mengenal pasti faktor-faktor yang paling dominan mempengaruhi lepak dengan hubungan keibubapaan. Seramai 500 orang pelajar dari 18 buah sekolah menengah iaitu Johor, Melaka, Negeri Sembilan dan Selangor... more
TEZ11913Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 2019.Kaynakça (s. 52-58) var.xii, 60 s. : res. (bzs. rnk.), tablo ; 29 cm.Tüm dünyada olduğu gibi ülkemizde de yetişkinler ve gençler arasında sentetik kannabinoid kullanımında... more
Programas de reducción de riesgos en atención a las drogodependencias: conceptos y acciones específicas
Programas de reducción de riesgos en atención a las drogodependencias: conceptos y acciones específicas
The opioid overdose epidemic continues to claim lives across the country with a record 47,600 overdose deaths in 2017. (This number represents 67.8% of the 70,237 overdose deaths from all drugs) [CDC 2018a]. More Americans now die every... more
Dit literatuurgedeelte bestaat uit een overzicht van de correlaten van depressie die mogelijks samenhangen met cognitieve inhibitie: een executieve functie waarbij men in staat is tot het onderdrukken van irrelevante informatie in het... more
Desde hace aproximadamente cinco anos, el Centro de Analisis politico de la Universidad EAFIT, en alianza con diversas entidades publicas y privadas, viene desarrollando una linea de investigacion en torno a las economias criminales y las... more
The aim of this study is to describe and analyze the parenting skills of fathers and mothers attending a prevention program on drug use and other risk behaviours, to fi nd out whether there are diff erences between mothers and fathers in... more
This article is eligible for Mainpro-M1 credits. To earn credits, go to www.cfp.ca and click on the Mainpro link. Mainpro-M1. Pour obtenir des crédits, allez à www.cfp.ca et cliquez sur le lien Mainpro. Cet article a fait l'objet d'une... more
Nel presente contributo ragiono attorno alla liceità o meno delle pratiche dopanti nello sport, in relazione alla richiesta di ipercompetitività e performatività imposta dalla società e dall'economia ultraliberista.
A range of commentators associated drug use with decadence in the late nineteenth century. 1 According to Fraser Harrison in his study of decadent male artists associated with the Yellow Book in the 1890s, "The threats and demands... more
Kertas ini bertujuan membentangkan hasil kajian yang meninjau penglibatan bapa dalam asuhan anak-anak remaja dan hubungannya dengan perkembangan remaja. Tinjauan dibuat terhadap 468 sampel pelajar dengan menggunakan soal selidik tentang... more
Kertas ini bertujuan membentangkan hasil kajian yang meninjau penglibatan bapa dalam asuhan anak-anak remaja dan hubungannya dengan perkembangan remaja. Tinjauan dibuat terhadap 468 sampel pelajar dengan menggunakan soal selidik tentang... more
Kertas ini bertujuan membentangkan hasil kajian yang meninjau penglibatan bapa dalam asuhan anak-anak remaja dan hubungannya dengan perkembangan remaja. Tinjauan dibuat terhadap 468 sampel pelajar dengan menggunakan soal selidik tentang... more
Background and Aims: Epidemiological transition in the form of noncommunicable diseases (NCDs) now becoming the main cause of mortality and morbidity is very much evident even in developing countries like India. Alcohol is an important... more
Bu calismanin amaci 13-25 yas grubu genclerde madde kullanim yayginligi ile madde kullanimi bakimindan risk etkenlerini arastirmaktir. Arastirma verileri 2010-2011 egitim yilinda 1750 lise, 361 universite ogrencisine uygulanan Saglikli... more
Human hair dated to Late Prehistory is exceedingly rare in the Western Mediterranean. Archaeological excavations in the Bronze Age burial and cult cave of Es Càrritx, in Menorca (Balearic Islands) provided some human hair strands involved... more
A descriptive survey of types, spread and characteristics of substance abuse treatment
Με το άρθρο γίνεται προσπάθεια στο πλαίσιο της σύγχρονης συζήτησης περί διακρίσεων και αποκλεισμών να προσδιοριστούν οι σημασίες που αποδίδονται στον όρο «ανάστροφος σεξισμός» (reverse sexism) σε σχέση με το ευρύτερο κοινωνικό φαινόμενο.... more
El proyecto también aprovecha los datos universitarios existentes (p. ej., del Registro Civil y de los Servicios de Salud). La recopilación remota de datos continúa cuando los participantes abandonan el campus. Los datos anónimos estarán... more
This Study investigate the Influence of Drug abuse on the academic performance of Students in tertiary institution with special reference to mathematics students in FCE Okene, Kogi state. The study adopted descriptive survey research... more
El dolor neuropático es un tipo de dolor de difícil manejo con una prevalencia próxima al 10% de la población. Actualmente, existen varios fármacos aprobados para su tratamiento agrupados en distintas líneas. Sin embargo, la eficacia... more
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