Cotta, 2004 - Google Patents

The role of the transcription factors Pax5 and E47 in early lymphopoiesis

Cotta, 2004

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9764547083587002877
Author
Cotta C
Publication year

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Hematopoiesis is regulated at multiple levels. Null mutations have identified several transcription factors important in lineage commitment, cell proliferation, and maturation. This thesis is focused on Pax5 and E47, which are two transcription factors demonstrated to be …
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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