Gao et al., 2019 - Google Patents

Rolling circle amplification integrated with suspension bead array for ultrasensitive multiplex immunodetection of tumor markers

Gao et al., 2019

Document ID
6156334636153130024
Author
Gao M
Lian H
Yu L
Gong M
Ma L
Zhou Y
Yu M
Yan X
Publication year
Publication venue
Analytica Chimica Acta

External Links

Snippet

Multiplex detection of ultra-low abundant tumor markers is extremely important for early diagnosis and therapy evaluation. Herein, an ultrasensitive multiplex immunoassay was developed by combination of rolling circle amplification (RCA) and suspension bead array …
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/543Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
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    • G01N33/54326Magnetic particles
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    • G01N33/54353Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
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