Katz et al., 2011 - Google Patents
Studying protein–protein interactions using peptide arraysKatz et al., 2011
View PDF- Document ID
- 16583333971494951167
- Author
- Katz C
- Levy-Beladev L
- Rotem-Bamberger S
- Rito T
- Rüdiger S
- Friedler A
- Publication year
- Publication venue
- Chemical Society Reviews
External Links
Snippet
Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging from small …
- 230000004850 protein–protein interaction 0 title abstract description 26
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Katz et al. | Studying protein–protein interactions using peptide arrays | |
| Lam et al. | Applications of one-bead one-compound combinatorial libraries and chemical microarrays in signal transduction research | |
| Kodadek | Protein microarrays: prospects and problems | |
| Duffner et al. | A pipeline for ligand discovery using small-molecule microarrays | |
| Schweitzer et al. | Microarrays to characterize protein interactions on a whole‐proteome scale | |
| Hall et al. | Protein microarray technology | |
| Sun et al. | Recent advances in microarray technologies for proteomics | |
| US7521253B2 (en) | Method for multiple target assay for drug discovery | |
| Myszka et al. | Implementing surface plasmon resonance biosensors in drug discovery | |
| Hansen et al. | Identification and mapping of linear antibody epitopes in human serum albumin using high-density peptide arrays | |
| JP4959691B2 (en) | Repeatable protein arrays | |
| Alberts et al. | Analyzing protein structure and function | |
| Kodadek et al. | Synthetic molecules as antibody replacements | |
| Volkmer | Synthesis and application of peptide arrays: quo vadis SPOT technology | |
| Kaushansky et al. | Quantifying protein–protein interactions in high throughput using protein domain microarrays | |
| JP6312225B2 (en) | Systematic exploration, maturation, and elongation of peptide binders for proteins | |
| Liu et al. | High‐throughput analysis of peptide‐binding modules | |
| US20100035765A1 (en) | Protein and Antibody Profiling Using Small Molecule Microarrays | |
| Löfås | Optimizing the hit-to-lead process using SPR analysis | |
| Busby et al. | Advancements in assay technologies and strategies to enable drug discovery | |
| Tozzi et al. | Affinity chromatography techniques based on the immobilisation of peptides exhibiting specific binding activity | |
| Carter et al. | B cell epitope mapping using synthetic peptides | |
| Beutling et al. | Large-scale analysis of protein–protein interactions using cellulose-bound peptide arrays | |
| Uttamchandani et al. | Site-specific peptide immobilization strategies for the rapid detection of kinase activity on microarrays | |
| Poluri et al. | Experimental methods for determination of protein–protein interactions |