Seder et al., 2024 - Google Patents
A scalable microfluidic platform for nanoparticle formulation: for exploratory-and industrial-level scalesSeder et al., 2024
View PDF- Document ID
- 15221046449258169020
- Author
- Seder I
- Zheng T
- Zhang J
- Rojas C
- Helalat S
- Téllez R
- Sun Y
- Publication year
- Publication venue
- Nano Letters
External Links
Snippet
Nanoparticle synthesis on microfluidic platforms provides excellent reproducibility and control over bulk synthesis. While there have been plenty of platforms for producing nanoparticles (NPs) with controlled physicochemical properties, such platforms often …
- 239000002105 nanoparticle 0 title abstract description 268
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
- B01F13/00—Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
- B01F13/0059—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
- B01F3/00—Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed
- B01F3/08—Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed liquids with liquids; Emulsifying
- B01F3/0807—Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
- B01F5/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F5/06—Mixers in which the components are pressed together through slits, orifices, or screens; Static mixers; Mixers of the fractal type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Carvalho et al. | Advanced microfluidic technologies for lipid nano-microsystems from synthesis to biological application | |
| Seder et al. | A scalable microfluidic platform for nanoparticle formulation: for exploratory-and industrial-level scales | |
| Osouli-Bostanabad et al. | Microfluidic manufacture of lipid-based nanomedicines | |
| Tomeh et al. | Recent advances in microfluidics for the preparation of drug and gene delivery systems | |
| Ortiz de Solorzano et al. | Continuous synthesis of drug-loaded nanoparticles using microchannel emulsification and numerical modeling: Effect of passive mixing | |
| Agha et al. | A review on microfluidic-assisted nanoparticle synthesis, and their applications using multiscale simulation methods | |
| Basak et al. | Liposome-based drug delivery systems: from laboratory research to industrial production—instruments and challenges | |
| Luo et al. | Microfluidic devices in fabricating nano or micromaterials for biomedical applications | |
| Belliveau et al. | Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA | |
| Maged et al. | Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects | |
| Molinaro et al. | Design and development of biomimetic nanovesicles using a microfluidic approach | |
| Vogelaar et al. | Use of microfluidics to prepare lipid-based nanocarriers | |
| Jahn et al. | Microfluidic mixing and the formation of nanoscale lipid vesicles | |
| Bokare et al. | Herringbone-patterned 3D-printed devices as alternatives to microfluidics for reproducible production of lipid polymer hybrid nanoparticles | |
| Lim et al. | Ultra-high throughput synthesis of nanoparticles with homogeneous size distribution using a coaxial turbulent jet mixer | |
| Khan et al. | Production of nanoparticle drug delivery systems with microfluidics tools | |
| Ekanem et al. | Structured biodegradable polymeric microparticles for drug delivery produced using flow focusing glass microfluidic devices | |
| Kim et al. | Mass production and size control of lipid–polymer hybrid nanoparticles through controlled microvortices | |
| Xu et al. | Microfluidic manufacturing of polymeric nanoparticles: comparing flow control of multiscale structure in single-phase staggered herringbone and two-phase reactors | |
| Zheng et al. | Preparation of drug-loaded liposomes with multi-inlet vortex mixers | |
| Amrani et al. | Characterization of nanoscale loaded liposomes produced by 2D hydrodynamic flow focusing | |
| Rawas-Qalaji et al. | Microfluidics in drug delivery: review of methods and applications | |
| VandenBerg et al. | Learning from the future: towards continuous manufacturing of nanomaterials | |
| Bovone et al. | Flow‐based reactor design for the continuous production of polymeric nanoparticles | |
| Wang et al. | Flow-directed loading of block copolymer micelles with hydrophobic probes in a gas–liquid microreactor |