Liu et al., 2015 - Google Patents

Synthetic mRNA reprogramming of human fibroblast cells

Liu et al., 2015

Document ID
12812578881375024364
Author
Liu J
Verma P
Publication year
Publication venue
Cell Reprogramming: Methods and Protocols

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Snippet

Reprogramming of somatic cells, such as skin fibroblasts, to pluripotency was first achieved by forced expression of four transcription factors using integrating retroviral or lentiviral vectors, which result in integration of exogenous DNA into cellular genome and present a …
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