Kwon et al., 2011 - Google Patents
Drug-eluting microarrays for cell-based screening of chemical-induced apoptosisKwon et al., 2011
View PDF- Document ID
- 12657329673404844348
- Author
- Kwon C
- Wheeldon I
- Kachouie N
- Lee S
- Bae H
- Sant S
- Fukuda J
- Kang J
- Khademhosseini A
- Publication year
- Publication venue
- Analytical chemistry
External Links
Snippet
Traditional high-throughput screening (HTS) is carried out in centralized facilities that require extensive robotic liquid and plate handling equipment. This model of HTS is restrictive as such facilities are not accessible to many researchers. We have designed a …
- 230000006907 apoptotic process 0 title abstract description 142
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Kwon et al. | Drug-eluting microarrays for cell-based screening of chemical-induced apoptosis | |
| Sun et al. | Recent advances in microfluidics for drug screening | |
| Cardoso et al. | Recent advances on cell culture platforms for in vitro drug screening and cell therapies: from conventional to microfluidic strategies | |
| Yu et al. | A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing | |
| Benz et al. | Marrying chemistry with biology by combining on-chip solution-based combinatorial synthesis and cellular screening | |
| Deiss et al. | Platform for high-throughput testing of the effect of soluble compounds on 3D cell cultures | |
| Sart et al. | Multiscale cytometry and regulation of 3D cell cultures on a chip | |
| Kang et al. | 3D droplet microfluidic systems for high-throughput biological experimentation | |
| Sugiura et al. | Microfluidic serial dilution cell-based assay for analyzing drug dose response over a wide concentration range | |
| Strutt et al. | Open microfluidics: droplet microarrays as next generation multiwell plates for high throughput screening | |
| Autebert et al. | Hierarchical hydrodynamic flow confinement: efficient use and retrieval of chemicals for microscale chemistry on surfaces | |
| Guan et al. | Facile and rapid generation of large-scale microcollagen gel array for long-term single-cell 3D culture and cell proliferation heterogeneity analysis | |
| JP2012519475A (en) | Apparatus and method for producing replicas or derivatives from an array of molecules and its application | |
| Li et al. | A plug-and-play, drug-on-pillar platform for combination drug screening implemented by microfluidic adaptive printing | |
| Sivagnanam et al. | Selective breast cancer cell capture, culture, and immunocytochemical analysis using self-assembled magnetic bead patterns in a microfluidic chip | |
| Delamarche et al. | Biopatterning: The art of patterning biomolecules on surfaces | |
| Dang et al. | Microfluidic actuation via 3D-printed molds toward multiplex biosensing of cell apoptosis | |
| Agrawal et al. | Devices and techniques used to obtain and analyze three‐dimensional cell cultures | |
| Michael et al. | Surface-engineered paper hanging drop chip for 3D spheroid culture and analysis | |
| Su et al. | Effect of microculture on cell metabolism and biochemistry: do cells get stressed in microchannels? | |
| Liu et al. | Large-scale antitumor screening based on heterotypic 3D tumors using an integrated microfluidic platform | |
| Jaberi et al. | Microfluidic systems with embedded cell culture chambers for high-throughput biological assays | |
| Kampe et al. | Modular microfluidic system for emulation of human phase I/phase II metabolism | |
| Grant et al. | High-throughput enzyme kinetics with 3D microfluidics and imaging SAMDI mass spectrometry | |
| WO2016005741A1 (en) | Cell positioning and analysis device |