WO2004035718A2 - Composition - Google Patents

Abstract

The invention relates to a composition, comprising: 0.1 to 40 wt. % of at least one oxidation-stable, at least mono-unsaturated, substituted or unsubstituted organic acid, 0.1 to 40 wt. % of at least one oxidation-stable, saturated, substituted or unsubstituted organic acid, up to 30 wt. % of hydrogen peroxide and/or at least one inorganic and/or organic peroxide compound and up to 2 wt. % of an oxidation-stable complexing agent. Said composition is an effective, widely applicable disinfecting, anti-bacterial and pharmaceutical agent, characterised by a good shelf life.

Description

composition

description

The present invention relates to a cleaning agent concentrate for dissolving biofouling and to a composition comprising at least one organic acid and at least one peroxide.

DE 43 25 312 A1, DE 199 10 356 A1 and DE 199 15 028 A1 disclose disinfectants in the form of an aqueous solution of a peroxide, food preservatives and non-toxic acids or their salts, in particular sodium benzoate and sorbic acid. However, due to their hydrogen peroxide content, these agents are not very stable in storage and, depending on their composition, lose their effectiveness within 1 to 3 months.

The object of the present invention is therefore to provide a composition of the type mentioned above which has a satisfactory sterilizing effect and improved storage stability.

The solution consists in a concentrate with the features of claim 1 or in a composition with the features of claim 2. The concentrate according to the invention contains from 0.1 to 4% by weight, preferably from 0.3 to 2.5%. -% of at least one substance from the group

Sorbic acid, sodium sorbate, potassium sorbate, lithium sorbate, ascorbic acid, acetylsalicylic acid, succinic acid or its salts and derivatives, from 0.1 to 4% by weight, preferably from 0.1 to 3.5% by weight, of at least one substance from the group benzoic acid , Sodium benzoate, lithium benzoate, p-hydroxybenzoic acid, maleic acid or its salts and derivatives, from 2.2 to 12 wt .-%, preferably 2.5 to 7.5 wt .-% 30% hydrogen peroxide, and from 0.1 to 1.5% by weight, preferably 0.1 to 1.3 % By weight of ethylenediaminetetraacetic acid, dissolved in preferably low-mineral water, in particular demineralized water.

The composition according to the invention contains 0.001 to 40% by weight of at least one oxidation-stable, at least monounsaturated, substituted or unsubstituted organic acid, 0.001 to 40% by weight of at least one oxidation-stable, saturated, substituted or unsubstituted organic acid, up to 30% by weight. % Hydrogen peroxide and / or at least one inorganic and / or organic peroxidic compound, and contains up to 2% by weight of an oxidation-stable complexing agent.

The composition according to the invention or the concentrate form a synergistic, multi-secured system of active ingredients that complement, add or reinforce their effect.

In the context of this invention, peroxidic compound is understood to mean all inorganic and organic compounds which contain a structural element of oxygen.

The release of oxygen radicals causes the peroxidic compound to rapidly oxidize the outer shell of cells, the outer shell being torn open and destroyed, so that the cell interior emerges outside. At the same time, enzymes that are supposed to intercept the oxygen radicals are destroyed or inhibited so quickly that they cannot fully develop their effect. Other proteins and nucleic acids are also attacked and damaged by the oxygen radicals. Eventually, the resulting blockage of the metabolic pathways (energy metabolism; protein biosynthesis) leads to cell death. This effect occurs very quickly. The peroxidic compound intervenes suddenly and massively in the cell structure, whereby it is broken down itself. So it is a strong but short-term effect. The organic acids ensure that the cell residues created in the process just described are broken down and thus prevent the formation of biofilms and bio-aggregates and the so-called biofouling. Existing biofilms and bio-aggregates are dissolved and broken down. Furthermore, they can form peracids for a short time under the influence of the peroxidic compound and thus supplement the effect of the peroxidic compound. By skilful selection of the individual acids, these effects can add, supplement or intensify. In contrast to the effect of the peroxidic compound, this effect is long-lasting since the organic acids are broken down only very slowly.

The complexing agent damages the germs to be combated by complexing Ca ²⁺ and Mg ²⁺ ions and thus removing them from the metabolism of the germs. In particular, however, the complexing agent complexes heavy metal ions, which catalyze the decomposition of the peroxidic compound. This protects the peroxidic compound from decomposition and thus stabilizes it.

Surprisingly, it has been found that this measure significantly increases the storage stability of the composition according to the invention, namely from 2 to 3 months to 1 to more than 2 years. The composition according to the invention is thus the first ever to be a marketable product which can be used without special precautions and preservation measures.

The composition of the invention is also non-toxic and biodegradable. It is brought into direct contact with the substrate to be treated. An effect occurs almost immediately and a complete cleaning effect can occur after just 10 to 20 minutes of exposure. Advantageous further developments result from the subclaims.

A preferred measure provides that the at least one oxidation-stable, at least monounsaturated organic acid is selected from the group comprising fruit acids, sorbic acid, maleic acid, fumaric acid and their salts. The at least one oxidation-stable saturated organic acid is preferably selected from the group comprising fruit acids, glycolic acid, lactic acid, succinic acid, oxalic acid, malonic acid, glutaric acid, adipic acid, pimelic acid, benzoic acid, p-hydroxybenzoic acid, straight-chain or branched alkanoic acids with 1 to 12 carbon atoms, and their salts.

The skillful combination of acids means that their effects are mutually reinforcing, supplementing or adding. Many organic acids, for example benzoic acid and sorbic acid, are metabolic poisons for many germs, so that they enhance the effect of the peroxidic compound on killing germs. Furthermore, they facilitate the membrane transfer of the peroxidic compound, damage the outer skin of the germs to be controlled and help stabilize the peroxidic compound.

Suitable peroxidic compounds include hydroperoxides, peroxides, e.g. urea peroxide, diacyl peroxides, peracids, peracid esters and epidioxides. Suitable inorganic peroxidic compounds are, for example, peroxomonosulfates, peroxodisulfates, peroxomonophosphates,

Peroxodiphosphate, Peroxomonocarbonate and Peroxodicarbonate. The choice depends on the formulation and the intended use of the composition according to the invention in individual cases. For example, hydrogen peroxide in liquid formulations and urea peroxide in solid formulations are particularly suitable. For example, ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), phosphoric acid, (poly) phosphoric acids, oxalic acid, acetoacetic acid and its salts and succinic acid derivatives can be used as complexing agents. These complexing agents complex metal ions particularly effectively, so that not only is the peroxidic compound stabilized in that the catalyst causing it to decay is no longer effective. Ions essential for the metabolism of the germs to be combated are also trapped, which contributes to the killing of these germs. The complexing agents mentioned also have the advantage that they are biodegradable.

Depending on the individual use, the composition according to the invention can contain numerous additives and auxiliaries. These include, for example, one or more oxidation-resistant degreasing agents which are selected from the group comprising soaps, anionic and nonionic surfactants, alkylbenzenesulfates, alkylbenzenesulfonates, fatty acid esters, sulfated fatty acid glycerides, betaines, sulfobetaines and. Saponins, preferably sodium dodecyl sulfate, sodium dodecyl sulfonate and sodium lauryl sulfate. Also conceivable are one or more oxidation-resistant permeation agents such as DMSO, straight-chain or branched, mono- or polyhydric alcohols with 1 to 12 carbon atoms and polyethylene glycols. It can also contain other auxiliaries such as defoamers, anti-corrosion agents, adhesives, wetting agents, fragrances and / or dyes.

By adding a highly emulsified vegetable oil component, for example soybean oil, insects are also directly affected by damage to their quinine shell.

The composition according to the invention can be formulated as a solution, as a solid or as a gel. For example, it can contain up to 99% by weight of at least one solvent such as water or one at room temperature contain liquid, branched or unbranched, mono- or polyhydric alkanol. For example, ethanol or isopropanol are suitable. The water is preferably demineralized. In alcohols as solvents, however, the constituents can be dissolved in larger amounts, so that concentrates result which are diluted before their use, for example in a dilution of 1:50 to 1: 2, or 1:40 to 1: 3 or 1 : 20 to 1: 5, preferably 1:10. Alcohols such as ethanol or isopropanol also have the advantage that they also have a bactericidal and fungicidal effect, which also increases the germicidal action of the composition according to the invention.

As a solution, the composition according to the invention is preferably weakly acidic to neutral, for example with a pH of 3.0 to 6.8.

A gel is used to formulate the gel

Composition at least one gelling agent added, preferably Aerosil, alginate, agarose or at least one acrylate. The resulting gel can then be applied to the surface to be treated.

A preferred formulation is, for example:

0.1 to 20 wt .-% H ₂ O ₂ or urea peroxide

0.01 to 1% by weight of sorbic acid

0.001 to 1 wt% benzoic acid

0.001 to 2% by weight EDTA or NTA 0.01 to 1% by weight H ₃ PO ₄ , phosphate or polyphosphate

85 to 99.798 wt% water (demin.).

The composition according to the invention also acts as a pharmaceutical in humans and animals, for example for the treatment of bacterial and viral infectious diseases, allergens, mycoses, pediculoses and other parasite infestation. It also acts as a bactericide, fungicide, insecticide and / or pesticide, preferably in agriculture, horticulture, as a tonic and / or care products for the treatment of plants and animals, as cleaning agents in the household and industry, as agents for air and water disinfection as well as for swimming pool and whirlpool disinfection and as surface disinfectants.

An embodiment of the present invention is described in more detail below. The composition contains: 50 g H ₂ 0 ₂ 1 g sorbic acid 2.5 g benzoic acid 1 g EDTA 1 g H ₃ P0 ₄ 1 IH ₂ 0 (demin.)

The water is initially introduced, then the EDTA is dissolved, then the acids are added and finally the hydrogen peroxide is added.

An aqueous 30% hydrogen peroxide solution was used to prepare the aqueous solution. Instead of hydrogen peroxide, urea peroxide or persulfate (as in Virkon) can also be used. In this case, a powder mixture is produced which contains an equivalent to 50 g of hydrogen peroxide of the peroxide used.

When formulated as a solid, the water and the others are omitted

Components, as well as the auxiliaries, if any, are supplied as a powdery mixture, as granules or in tablet form.

By adding ethanol or isopropanol to the formulation mentioned above, the solubility of benzoic acid and sorbic acid can be increased very far (up to the solubility limit), so that a "Super concentrate" can be produced with about 10 times the active substance content (for example 10 g sorbic acid, 25 g benzoic acid and 10% or more H ₂ 0 ₂ ).

The composition according to the invention was tested for the following areas of application and found to be effective:

Agricultural Products:

- Strengthening of trees against Phytophthora ramorum and bark beetles by spraying; preferably in a composition of 0.5%

H ₂ 0 ₂ , 0.01% sorbic acid, 0.025% benzoic acid, 0.001% EDTA, 0.1% H ₃ P0 ₄ , in demineralized water.

- Strengthening of tobacco plants against the tobacco mosaic virus, against aphids and against the root and stem rot by spraying.

- Strengthening potato plants against late blight (Phytophthora infestans) and Colorado beetles (Leptinotarsa decemlineata) by spraying; preferably in a composition of 0.5% H ₂ 0 ₂ , 0.01% sorbic acid, 0.025% benzoic acid, 0.001% EDTA, 0.1%

H ₃ P0 ₄ , in demineralized water.

- Strengthening cucumber plants against downy mildew, against aphids, spider mites and thrips by spraying; preferably in a composition of 0.5% H ₂ O ₂ , 0.01% sorbic acid, 0.025%

Benzoic acid, 0.001% EDTA, 0.1% H ₃ PO ₄ , in demineralized water.

- Strengthening the resistance of cabbage plants to thrips, bacterial leaf spot disease, vein blackness, cabbage blackness, ring spot disease, insects, mites and nematodes

Spray; preferably in a composition of 0.5% H ₂ O ₂ , 0.01% sorbic acid, 0.025% benzoic acid, 0.001% EDTA, 0.1% H ₃ P0 ₄ , in demineralized water.

- Strengthening the vine against, among other things, downy and powdery mildew (Plasmopara viticola and Oidium tuckeri) or against Pierce

Disease by spraying. In this area in particular, the use of copper and sulfur preparations in organic viticulture or of fungicides in conventional viticulture can be dispensed with or greatly reduced by using this agent. A composition of 0.5% H ₂ O ₂ , 0.01% sorbic acid, for example, is effective.

0.025% benzoic acid, 0.001% EDTA, 0.1% H ₃ PO ₄ , 0.5% SDS in demineralized water.

Agriculture:

- Aid in cleaning stables by atomization. Bacteria and fungi, for example mold, are successfully combated here, and the composition according to the invention also has a deodorant effect by killing odor-forming germs. A composition of 3.5% H ₂ 0 ₂ , 0.1% sorbic acid, 0.25% is effective, for example.

Benzoic acid, 0.1% EDTA, 0.1% H ₃ PO ₄ , 0.5% SDS in demineralized water.

- Help with animal fur and feather care by spraying. It can be used against fungi (e.g. skin or mold), against bacteria, viruses and

Algae are used. It works in the care of fur and feathers against mites and skin fungi and in the cleaning and disinfection of small wounds. In addition, the composition according to the invention has a deodorizing effect by killing odor-forming germs. A composition of 0.5% H ₂ O ₂ , 0.01% sorbic acid, for example, is effective.

0.015% benzoic acid, 0.01% EDTA, 0.01% H ₃ PO ₄ , 0.05% DMSO, 0.5% SDS in demineralized water. - Help with hoof and claw care of animals by applying a solution. It works against mauke and other diseases that affect the hooves and claws of animals. A composition of 1.5% H ₂ O ₂ , 0.1% sorbic acid, 0.15% is effective, for example.

Benzoic acid, 0.1% EDTA, 0.1% H ₃ PO ₄ , 0.05% DMSO, 0.5% SDS in demineralized water.

- Help with the care of bees against mites, fungi and bacteria that affect the bee and the hive. The invention

Composition is atomized in the beehive. A composition of 0.3% H ₂ O ₂ , 0.1% sorbic acid, 0.2% benzoic acid, 0.1% EDTA, 0.1% H ₃ PO ₄ , for example, is effective in demineralized water.

In the food industry, the composition according to the invention can be used, for example, for the external treatment of fruits, but also for the disinfection of water and for the disinfection of processing machines. This is particularly unproblematic because the composition according to the invention is non-toxic and biodegradable. A composition of 0.3% H ₂ O ₂ , 0.05% sorbic acid, 0.1% benzoic acid, 0.01% EDTA, 0.1% H ₃ P0 ₄ in demineralized water is suitable, for example. Hygienic processing of food is made possible by keeping production plants free of microorganisms and biofilm material. The composition according to the invention can also be contained in or mixed with the ice in a concentration suitable for the development of the effects described, so that its cleaning action occurs in the course of melting and, for example, biofilm formation from the ice-filled cold rooms on a fish trawler to serving in the Fish restaurant remains excluded and the original freshness of the fish remains guaranteed. The composition according to the invention is also for leather care, for cleaning and disinfecting surfaces, pipes and hoses, in particular also for medical devices and apparatus, for cleaning and disinfecting water tanks, air conditioning systems, sanitary facilities, cooling and hot water systems, drinking water systems and waste water systems Air and water disinfection, suitable as surface disinfectant, for drinking water treatment and for swimming pool and whirlpool disinfection. A composition of 5% H ₂ O ₂ , 0.1% sorbic acid, 0.25% benzoic acid, 0.1% EDTA, 0.1% H ₃ PO in demineralized water is suitable for this. For more sensitive surfaces and for use in the sauna, solarium, pool and whirlpool, for example, a composition of 3% H ₂ 0 ₂ , 0.1% sorbic acid, 0.25% benzoic acid, 0.1% EDTA, 0.1% H ₃ PO ₄ , can be used in demineralized water.

If more foaming is observed when treating surfaces, this is an indication of a high degree of contamination of these surfaces, so that repetition of the treatment or treatment with a higher concentration of the composition is advisable.

A specific example of the mode of action of the composition according to the invention is the cleaning of old, moldy leather harnesses for horses, for example riding horses. After spraying with the composition specified above and an exposure time of 10 to 15 minutes, not only can the mildew covering be easily wiped off, but the old, hard leather also becomes supple and soft again and remains permanently supple after oil treatment. Through long years of contamination, a solid biofouling structure had formed in the pores of the leather, which had hardened the leather considerably. The treatment by the composition according to the invention frees the pores from the biofilm material and makes them supple again, so that the agent could penetrate the pores. Leather shoes can also be treated in the same way.

Another example is clean room air treatment. By adding to the air, the microorganisms are killed directly. On the other hand, the biofilm material that surrounds agglomerations of microorganisms and ensures cohesion in the air is dissolved and any agglomeration of microorganisms that make up about 1/10 of the residual dust falls apart. The microorganisms also perish here. The natural moisture content of

Indoor air can be enriched with the composition according to the invention. This ensures that the air is enriched with a fine mist of aerosol particles of <3μ if possible, so that the composition is distributed throughout the room and unfolds its effect. The aerosol particles get into the ventilated rooms and in them on all furnishings and materials (e.g. fabrics, clothing, food supplies etc.). This results in a cleaning effect, so that permanent freedom from biofilm is guaranteed. In this way, not only the air supply devices, for example air conditioning systems, are cleaned of any biofilm deposits, so that no more microorganisms are spread, but also the biofilm clusters of microorganisms within the ventilated room are removed. This is also advantageous for storage rooms of all kinds because, for example, a considerable saving in cooling energy is possible. Such air cleaning can also be used for transport containers of all kinds (in addition to wiping the surfaces themselves), so that the transported goods (for example fruit) are kept clean and preserved. Furthermore, air and water filters work noticeably more effectively if they are kept free of biofilm material.

As a medicament, the composition according to the invention is, inter alia, against SARS coronavirus, Bacillus anthracis, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus faecalis, Proteus mirabilis, Mycobacterium tuberculosis, Clostridium sporogens, Candida albicans, dust mites, varroa mites and many other pathogens and parasites are effective. For example, it can be inhaled or applied to infested areas, for example in a composition of 3% H ₂ O ₂ , 0.1% sorbic acid, 0.25% benzoic acid, 0.1% EDTA, 0.1% H ₃ P0 ₄ , in demineralized water (preferably for inhalation) or in a composition of 1.5% H ₂ O ₂ , 0.1% sorbic acid, 0.15% benzoic acid, 0.1% EDTA, 0.1% H ₃ PO ₄ , 0.05% DMSO in demineralized water (preferably for application).

With the killing of all kinds of germs achieved by the composition according to the invention on the one hand and the reduction or removal of biofilms, any germs such as bacteria, viruses, fungi, protozoa etc. are deprived of the possibility of spreading. Although such germs or biofilms for multicellular animals such as mites, mosquitoes, flies, worms, but also

Mice and rats are not necessary for existence, it has been observed that the environment cleaned with the composition according to the invention is at least avoided by these animals, so that, for example, the number of flies and mosquitoes is at least reduced in animal stalls.

The composition according to the invention thus represents an effective biological disinfectant and disinfectant as well as pesticide. Since biofilm or biofouling can occur in all areas in which an infestation of microorganisms is possible, the composition according to the invention is economical everywhere and in particular in a biologically relevant temperature range can be used up to approx. 70 ° C.

It is also effective against various pathogens. The composition according to the invention is user-friendly and environmentally friendly, non-toxic and completely biodegradable. It shows a very large one Range of effects and enables safe and effective infection control for a variety of applications, e.g.

Agriculture, horticulture and forestry: plant strengthening / plant protection through plant and tree treatment, e.g. mildew, aphids, mites, bacteria, post harvest treatment

Pharmaceutical industry:

Germicidal drugs, e.g. wound disinfectants, inhalation drugs (SARS, TBC, influenza etc.), athlete's foot and nail fungus, warts.

Industry:

Cleaning of pipes and surfaces, removal and prevention of biofilms, e.g. in air conditioning systems, sanitary facilities, cooling and hot water systems, drinking water systems, sewage systems, keeping drinking and industrial water and air clean, treatment of textiles, leather, wood.

Food industry:

Harvest fruit treatment, food processing, transportation and storage of food, e.g. treatment of fruits, processing machines, water.

Household / Hotel:

Keeping sanitary facilities, air conditioning, sauna, solariums, pool, whirlpool clean.

Animal husbandry: Varoa mites in bees, hoof and hoof care, fur care,

Water conservation in fish and shrimp farming, stall disinfection.

Claims

claims 1. concentrate of a cleaning agent for dissolving biofouling, consisting of a combination a) from 0.1 to 4% by weight, preferably from 0.3 to 2.5% by weight, of at least one substance from the group sorbic acid, sodium sorbate, Potassium sorbate, lithium sorbate, ascorbic acid, acetylsalicylic acid, succinic acid or its salts and derivatives, b) from 0.1 to 4% by weight, preferably from 0.1 to 3.5% by weight, of at least one substance from the group benzoic acid, Sodium benzoate, lithium benzoate, p-hydroxybenzoic acid, maleic acid or its salts and derivatives, c) from 2.2 to 12% by weight, preferably 2.5 to 7.5% by weight of 30% hydrogen peroxide, and d) from 0 , 1 to 1.5% by weight, preferably 0.1 to 1.3% by weight, of ethylenediaminetetraacetic acid, dissolved e) in preferably low-mineral water, in particular demineralized water. 2. Composition comprising: a) 0.001 to 40% by weight of at least one oxidation-stable, at least monounsaturated, substituted or unsubstituted organic acid, b) 0.001 to 40% by weight of at least one oxidation-stable, saturated, substituted or unsubstituted organic acid, c) up to 30% by weight of hydrogen peroxide and / or at least one inorganic and / or organic peroxidic compound, d) up to 2% by weight of an oxidation-stable complexing agent. 3. Composition according to claim 2, characterized in that the at least one oxidation-stable at least monounsaturated organic acid is selected from the group comprising fruit acids, sorbic acid, maleic acid, fumaric acid and their salts. 4. Composition according to claim 2 or 3, characterized in that the at least one oxidation-stable saturated organic acid is selected from the group comprising fruit acids, glycolic acid, lactic acid, succinic acid, oxalic acid, malonic acid, Glutaric acid, adipic acid, pimelic acid, benzoic acid, p-hydroxybenzoic acid, straight-chain or branched alkanoic acids with 1 to 12 carbon atoms, and their salts. 5. Composition according to one of claims 2 to 4, characterized in that the at least one organic peroxide compound is selected from the group comprising hydroperoxides, peroxides, diacyl peroxides, peracids, peracid esters, ketone peroxides and epidioxides. 6. Composition according to one of claims 2 to 5, characterized in that the at least one inorganic peroxidic compound is selected from the group comprising peroxomonosulfates, peroxodisulfates, peroxomonophosphates, peroxodiphosphates, peroxomonocarbonates and peroxodicarbonates. 7. Composition according to one of claims 2 to 6, characterized in that the at least one oxidation-stable complexing agent is selected from the group comprising ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), Phosphoric acid, (poly) phosphoric acids, oxalic acid, acetoacetic acid and its salts and succinic acid derivatives. A concentrate or composition according to any one of the preceding claims, further comprising at least one oxidation-resistant degreasing agent which is selected from the group comprising soaps, anionic and nonionic surfactants, alkylbenzenesulfates, Alkylbenzenesulfonates, fatty acid esters, sulfated fatty acid glycerides, betaines, sulfobetaines and saponins, preferably sodium dodecyl sulfate, sodium dodecyl sulfonate and sodium lauryl sulfate. 9. concentrate or composition according to any one of the preceding claims, further comprising at least one oxidation-resistant permeation agent such as DMSO, straight-chain or branched, mono- or polyhydric alcohols having 1 to 12 carbon atoms and polyethylene glycols. 10. concentrate or composition according to any one of the preceding claims, further comprising one or more other auxiliaries such as defoamers, anti-corrosion agents, adhesives, wetting agents, fragrances and dyes and highly emulsified vegetable oil. 11. Concentrate or composition according to one of the preceding claims, further comprising at least one solvent such as water or a liquid, branched or unbranched, monohydric or polyhydric alcohol, for example ethanol or isopropanol, at room temperature. 12. Concentrate or composition according to one of the preceding claims, characterized by a pH of 3.0 to 6.8 in dissolved form. 13. A concentrate or composition according to claim 11 or 12, further comprising at least one gelling agent, preferably Aerosil, alginate, agarose or at least one acrylate. 14. Concentrate or composition according to one of the preceding claims, comprising: 0.1 to 10 wt .-% H ₂ 0 ₂ or urea peroxide 0.01 to 1 wt .-% sorbic acid 0.001 to 1 wt .-% benzoic acid 0.001 to 2 wt .-% EDTA or NTA 0.01 to 1 wt .-% H ₃ P0 ₄ , phosphate or polyphosphate 85 to 99.798 wt .-% water (demin.). 15. concentrate or composition according to any one of the preceding claims for use as a medicament. 16. Use of the concentrate or the composition according to any one of claims 1 to 13 for the manufacture of medicaments for Treatment of bacterial and viral infectious diseases, mycoses, pediculoses and other parasite infections. 17. Use of the concentrate or the composition according to any one of claims 1 to 13 as a bactericide, fungicide, insecticide and / or pesticide, preferably in agriculture, horticulture, as a tonic and / or maintenance agent for the treatment of plants and animals, as Cleaning agents in household and industry, as a means for air and water disinfection as well as for swimming pool and whirlpool disinfection as well as surface disinfectants. 18. Use according to one of claims 16 to 17, wherein the concentrate or the composition in a dilution of 1:50 to 1: 2, preferably 1:40 to 1: 3, particularly preferably 1:20 to 1: 5, in particular 1:10, is used.