SG11201804704PA - Compositions and methods for decreasing tau expression - Google Patents

Compositions and methods for decreasing tau expression

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Publication number
SG11201804704PA
SG11201804704PA SG11201804704PA SG11201804704PA SG11201804704PA SG 11201804704P A SG11201804704P A SG 11201804704PA SG 11201804704P A SG11201804704P A SG 11201804704PA SG 11201804704P A SG11201804704P A SG 11201804704PA SG 11201804704P A SG11201804704P A SG 11201804704PA
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Singapore
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international
compositions
rule
methods
pct
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SG11201804704PA
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Ofengeim Manuela Polydoro
Jan Weiler
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Novartis Ag
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Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -' Organization International Bureau ristspi id (43) International Publication Date .... .....r ,„„01 29 June 2017(29.06.2017) WIPO I PCT ID Hit (10) 1111111111111111111 WO International Ell 2017/109679 Publication 1111111111111111111111111111111t111111111IIIIII Al Number (51) International Patent Classification: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, C12N 15/113 (2010.01) KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (21) International Application Number: NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, PCT/IB2016/057794 RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (22) International Filing Date: TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, 19 December 2016 (19.12.2016) ZA, ZM, ZW. (25) Filing Language: English (8 4 ) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (26) Publication Language: English GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (30) Priority Data: TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, 62/270,165 21 December 2015 (21.12.2015) US TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, (71) Applicant: NOVARTIS AG [CH/CH]; Lichtstrasse 35, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, 4056 Basel (CH). SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (72) Inventors: POLYDORO OFENGEIM, Manuela; No yards Institutes for BioMedical Research, Inc., 250 Mas- Declarations under Rule 4.17: sachusetts Ave., Cambridge, MA 02139 (US). WEILER, — as to applicant's entitlement to apply for and be granted a Jan; Novartis Institutes for BioMedical Research, Inc., 250 patent (Rule 4.170) Massachusetts Ave., Cambridge, MA 02139 (US). Published: (74) Agent: NOVARTIS AG; Lichtstrasse 35, 4056 Basel (CH). — with international search report (Art 21(3)) — before the expiration of the time limit for amending the (81) Designated States (unless otherwise indicated, for every kind AE, AG, AL, AM, claims and to be republished in the event of receipt of of national protection available): AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, amendments (Rule 48.2(h)) BZ, DE, DJ, DK, DM, CA, CH, CL, CN, CO, CR, CU, CZ, _ with sequence listing part of description (Rule 5.2(a)) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, 1-1 .4t Cr \ IN Cr \ C::: , 11 IN 11 C::: , ei (54) Title: COMPOSITIONS AND METHODS FOR DECREASING TAU EXPRESSION 52 (57) : Provided herein are compositions and methods for decreasing tau mRNA and protein expression. These compositions and methods are useful in treating tau-related diseases and disorders.
SG11201804704PA 2015-12-21 2016-12-19 Compositions and methods for decreasing tau expression SG11201804704PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562270165P 2015-12-21 2015-12-21
PCT/IB2016/057794 WO2017109679A1 (en) 2015-12-21 2016-12-19 Compositions and methods for decreasing tau expression

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SG11201804704PA true SG11201804704PA (en) 2018-07-30

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EP (3) EP4406541A3 (en)
JP (4) JP7027328B2 (en)
KR (2) KR20250112919A (en)
CN (2) CN109072237B (en)
AR (1) AR107579A1 (en)
AU (2) AU2016376034B2 (en)
CA (1) CA3008094A1 (en)
CL (3) CL2018001652A1 (en)
CO (1) CO2018006297A2 (en)
CR (1) CR20200609A (en)
CU (1) CU24574B1 (en)
DK (1) DK3394259T3 (en)
DO (1) DOP2018000151A (en)
EA (2) EA036417B1 (en)
EC (1) ECSP18050575A (en)
ES (1) ES2984631T3 (en)
FI (1) FI3394259T3 (en)
HR (1) HRP20240672T1 (en)
HU (1) HUE066548T2 (en)
IL (3) IL305866B2 (en)
JO (2) JO3790B1 (en)
LT (1) LT3394259T (en)
MA (2) MA44426B1 (en)
MX (2) MX2018007726A (en)
MY (1) MY191737A (en)
PE (2) PE20241069A1 (en)
PH (1) PH12018501207B1 (en)
PL (1) PL3394259T3 (en)
PT (1) PT3394259T (en)
RS (1) RS65535B1 (en)
RU (1) RU2747734C2 (en)
SA (1) SA518391831B1 (en)
SG (2) SG11201804704PA (en)
SI (1) SI3394259T1 (en)
SV (1) SV2018005714A (en)
TW (2) TWI834177B (en)
UY (1) UY37038A (en)
WO (1) WO2017109679A1 (en)
ZA (1) ZA201803661B (en)

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