PL2470173T3 - Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors - Google Patents
Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitorsInfo
- Publication number
- PL2470173T3 PL2470173T3 PL10812593.1T PL10812593T PL2470173T3 PL 2470173 T3 PL2470173 T3 PL 2470173T3 PL 10812593 T PL10812593 T PL 10812593T PL 2470173 T3 PL2470173 T3 PL 2470173T3
- Authority
- PL
- Poland
- Prior art keywords
- taxane
- combination therapy
- nanoparticle compositions
- hedgehog inhibitors
- hedgehog
- Prior art date
Links
- 241000289669 Erinaceus europaeus Species 0.000 title 1
- 229940123237 Taxane Drugs 0.000 title 1
- 238000002648 combination therapy Methods 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nanotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23681309P | 2009-08-25 | 2009-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2470173T3 true PL2470173T3 (en) | 2016-11-30 |
Family
ID=43628371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10812593.1T PL2470173T3 (en) | 2009-08-25 | 2010-08-25 | Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20130045240A1 (en) |
| EP (2) | EP3103452A1 (en) |
| JP (1) | JP2013503174A (en) |
| KR (1) | KR20120053052A (en) |
| CN (1) | CN102573832B (en) |
| AU (1) | AU2010286670B2 (en) |
| BR (1) | BR112012004149A2 (en) |
| CA (1) | CA2772301A1 (en) |
| CR (1) | CR20120115A (en) |
| DK (1) | DK2470173T3 (en) |
| ES (1) | ES2577024T3 (en) |
| HR (1) | HRP20160551T8 (en) |
| HU (1) | HUE029094T2 (en) |
| IL (1) | IL218316A (en) |
| IN (1) | IN2012DN02018A (en) |
| MX (1) | MX340670B (en) |
| MY (1) | MY162514A (en) |
| NI (1) | NI201200030A (en) |
| NZ (1) | NZ598588A (en) |
| PL (1) | PL2470173T3 (en) |
| PT (1) | PT2470173E (en) |
| RU (1) | RU2561055C2 (en) |
| SG (2) | SG10201609290PA (en) |
| UA (1) | UA110196C2 (en) |
| WO (1) | WO2011025838A1 (en) |
| ZA (1) | ZA201201531B (en) |
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| SI1853250T1 (en) | 2005-02-18 | 2012-01-31 | Abraxis Bioscience Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| US8735394B2 (en) * | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| KR101420445B1 (en) * | 2005-08-31 | 2014-07-16 | 아브락시스 바이오사이언스, 엘엘씨 | Composition comprising water-insoluble pharmaceutical agent and antimicrobial agent |
| EP3470071A1 (en) | 2006-12-14 | 2019-04-17 | Abraxis BioScience, LLC | Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane |
| WO2008109163A1 (en) * | 2007-03-07 | 2008-09-12 | Abraxis Bioscience, Llc. | Nanoparticle comprising rapamycin and albumin as anticancer agent |
| JP5579057B2 (en) * | 2007-06-01 | 2014-08-27 | アブラクシス バイオサイエンス， エルエルシー | Methods and compositions for the treatment of recurrent cancer |
| US8748623B2 (en) | 2009-02-17 | 2014-06-10 | Syntrix Biosystems, Inc. | Pyridinecarboxamides as CXCR2 modulators |
| HRP20192259T1 (en) | 2009-04-15 | 2020-03-06 | Abraxis Bioscience, Llc | PREPARATIONS OF NON-PARTICLES WITHOUT PRION AND METHODS OF THEIR PRODUCTION |
| CA3051495A1 (en) | 2010-03-26 | 2011-09-29 | Abraxis Bioscience, Llc | Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma |
| KR20130028727A (en) | 2010-03-29 | 2013-03-19 | 아브락시스 바이오사이언스, 엘엘씨 | Methods of enhancing drug delivery and effectiveness of therapeutic agents |
| NZ717490A (en) | 2010-03-29 | 2017-12-22 | Abraxis Bioscience Llc | Methods of treating cancer |
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| US10682415B2 (en) | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
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| JP7832108B2 (en) | 2019-10-28 | 2026-03-17 | アブラクシス バイオサイエンス， エルエルシー | Pharmaceutical composition of albumin and rapamycin |
| CN112755042A (en) * | 2019-11-06 | 2021-05-07 | 绍兴维帆生物技术有限公司 | Method for treating leukemia by using antitumor drugs in combination |
| KR102526793B1 (en) * | 2021-11-03 | 2023-04-28 | 주식회사 에스엔바이오사이언스 | Method for preparing albumin bound taxane nanoparticles with improved particle size distribution maintenance stability |
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-
2010
- 2010-08-25 PL PL10812593.1T patent/PL2470173T3/en unknown
- 2010-08-25 HU HUE10812593A patent/HUE029094T2/en unknown
- 2010-08-25 DK DK10812593.1T patent/DK2470173T3/en active
- 2010-08-25 JP JP2012526948A patent/JP2013503174A/en active Pending
- 2010-08-25 PT PT108125931T patent/PT2470173E/en unknown
- 2010-08-25 EP EP16167017.9A patent/EP3103452A1/en not_active Withdrawn
- 2010-08-25 MX MX2012002460A patent/MX340670B/en active IP Right Grant
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