MX2016015610A - Agentes inmunorreguladores. - Google Patents

Agentes inmunorreguladores.

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Publication number
MX2016015610A
MX2016015610A MX2016015610A MX2016015610A MX2016015610A MX 2016015610 A MX2016015610 A MX 2016015610A MX 2016015610 A MX2016015610 A MX 2016015610A MX 2016015610 A MX2016015610 A MX 2016015610A MX 2016015610 A MX2016015610 A MX 2016015610A
Authority
MX
Mexico
Prior art keywords
compounds
immunoregulatory agents
dioxygenase
indoleamine
disorders
Prior art date
Application number
MX2016015610A
Other languages
English (en)
Inventor
Carlos Jaen Juan
Osipov Maksim
Patrick Powers Jay
Ross Walker James
Zibinsky Mikhail
Paul Shunatona Hunter
Original Assignee
Flexus Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flexus Biosciences Inc filed Critical Flexus Biosciences Inc
Publication of MX2016015610A publication Critical patent/MX2016015610A/es

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    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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Abstract

La presente invención se refiere a compuestos que modulan la enzima de oxidoreductasa de indolamina 2,3-dioxigenasa, y a las composiciones que contienen los compuestos. También se proporciona el uso de tales compuestos y composiciones para el tratamiento y/o la prevención de un conjunto diverso de enfermedades, trastornos y afecciones, que son mediadas por la indolamina 2,3-dioxigenasa.
MX2016015610A 2014-06-06 2015-06-05 Agentes inmunorreguladores. MX2016015610A (es)

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