MX2009006638A - Agente para erradicar helicobacter pylori que tiene actividad inhibidora sobre la secrecion de acido gastrico. - Google Patents

Agente para erradicar helicobacter pylori que tiene actividad inhibidora sobre la secrecion de acido gastrico.

Info

Publication number
MX2009006638A
MX2009006638A MX2009006638A MX2009006638A MX2009006638A MX 2009006638 A MX2009006638 A MX 2009006638A MX 2009006638 A MX2009006638 A MX 2009006638A MX 2009006638 A MX2009006638 A MX 2009006638A MX 2009006638 A MX2009006638 A MX 2009006638A
Authority
MX
Mexico
Prior art keywords
helicobacter pylori
gastric acid
acid secretion
compound
inhibitory activity
Prior art date
Application number
MX2009006638A
Other languages
English (en)
Inventor
Masaharu Ito
Masaichi Yamamoto
Original Assignee
Arigen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arigen Pharmaceuticals Inc filed Critical Arigen Pharmaceuticals Inc
Publication of MX2009006638A publication Critical patent/MX2009006638A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describe: un compuesto que es estable en un ácido, tiene un efecto antibacteriano contra una bacteria Helicobacter py!ori, puede ejercer un nivel satisfactorio de un efecto antibacteriano cuando se usa solo, no afecta una bacteria entérica, tiene un efecto antibacteriano contra una bacteria resistente a un agente antibacteriano, y tiene un efecto inhibidor sobre la secreción de ácido gástrico; y una composición farmacéutica que contiene el compuesto. Se describe específicamente: un compuesto representado por la fórmula general (I) o una sal de él; y una composición farmacéutica que contiene el compuesto (I) o la sal de él, caracterizado además porque R representa un grupo alquilo lineal que tiene de 4 a 8 átomos de carbono, preferiblemente de 5 a 7 átomos de carbono.
MX2009006638A 2006-12-18 2007-12-18 Agente para erradicar helicobacter pylori que tiene actividad inhibidora sobre la secrecion de acido gastrico. MX2009006638A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006340323 2006-12-18
PCT/JP2007/001419 WO2008075462A1 (ja) 2006-12-18 2007-12-18 胃酸分泌抑制作用を併せ持つヘリコバクター・ピロリ除菌剤

Publications (1)

Publication Number Publication Date
MX2009006638A true MX2009006638A (es) 2009-07-02

Family

ID=39536102

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006638A MX2009006638A (es) 2006-12-18 2007-12-18 Agente para erradicar helicobacter pylori que tiene actividad inhibidora sobre la secrecion de acido gastrico.

Country Status (16)

Country Link
US (1) US8778975B2 (es)
EP (1) EP2103608B1 (es)
JP (1) JP5097126B2 (es)
KR (1) KR101283682B1 (es)
CN (1) CN101553480B (es)
AU (1) AU2007335663B2 (es)
BR (1) BRPI0720539A2 (es)
CA (1) CA2671949C (es)
DK (1) DK2103608T3 (es)
ES (1) ES2390611T3 (es)
MX (1) MX2009006638A (es)
PL (1) PL2103608T3 (es)
PT (1) PT2103608E (es)
RU (1) RU2451682C2 (es)
SI (1) SI2103608T1 (es)
WO (1) WO2008075462A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1014314A2 (pt) * 2009-04-09 2019-09-24 Arigen Pharmaceuticals Inc derivado de tiopiridina, e, composição farmacêutica.
CN110003177B (zh) * 2019-05-28 2021-11-19 沈阳药科大学 含有脲基的苯并咪唑类化合物及应用
CN110003176B (zh) * 2019-05-28 2021-12-21 沈阳药科大学 含有酰胺的苯并咪唑类化合物及其应用
JP2023517660A (ja) 2020-03-13 2023-04-26 ヤンセン バイオテツク，インコーポレーテツド シグレック３／ｃｄ３３に結合させるための材料及び方法
CN116249714A (zh) 2020-05-27 2023-06-09 詹森生物科技公司 包含cd3抗原结合结构域的蛋白质及其用途
CN117098781A (zh) 2021-03-24 2023-11-21 詹森生物科技公司 靶向cd22和cd79b的抗体
US12084501B2 (en) 2021-03-24 2024-09-10 Janssen Biotech, Inc. Proteins comprising CD3 antigen binding domains and uses thereof
US20250019455A1 (en) 2021-09-24 2025-01-16 Pharmaceutica Nv Proteins comprising cd20 binding domains, and uses thereof
CN117534657B (zh) * 2023-11-20 2024-10-15 湖北省医药工业研究院有限公司 雷贝拉唑类似物的合成方法及应用
TW202535382A (zh) * 2023-11-29 2025-09-16 南韓商第一藥品股份有限公司 包含ｚａｓｔａｐｒａｚａｎ或其醫藥上可接受的鹽之用於幽門螺旋桿菌根除的組成物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA825106B (en) 1981-08-13 1983-04-27 Haessle Ab Novel pharmaceutical compositions
SE8300736D0 (sv) 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6150979A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
JP2694361B2 (ja) 1989-02-09 1997-12-24 アストラ アクチエボラグ 抗菌剤
JPH0720865B2 (ja) 1989-02-10 1995-03-08 武田薬品工業株式会社 抗菌剤
JPH0348680A (ja) 1989-07-18 1991-03-01 Yoshitomi Pharmaceut Ind Ltd 抗菌剤
JP2798588B2 (ja) 1992-08-21 1998-09-17 エーザイ株式会社 抗菌剤
CN1157610A (zh) * 1994-07-20 1997-08-20 比克·古尔顿·劳姆贝尔格化学公司 抗螺杆菌的吡啶基硫基化合物
ES2171116B1 (es) * 2000-04-14 2003-08-01 Esteve Quimica Sa Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol.
CA2480890A1 (en) * 2002-03-29 2003-10-09 Zeria Pharmaceutical Co., Ltd. 1-n-aminobenzimidazole derivatives

Also Published As

Publication number Publication date
US8778975B2 (en) 2014-07-15
PL2103608T3 (pl) 2013-02-28
RU2009127750A (ru) 2011-01-27
ES2390611T3 (es) 2012-11-14
EP2103608B1 (en) 2012-08-29
WO2008075462A1 (ja) 2008-06-26
EP2103608A4 (en) 2010-12-22
RU2451682C2 (ru) 2012-05-27
HK1131149A1 (en) 2010-01-15
PT2103608E (pt) 2012-09-24
CA2671949C (en) 2011-11-01
DK2103608T3 (da) 2012-09-17
CN101553480A (zh) 2009-10-07
KR101283682B1 (ko) 2013-07-08
SI2103608T1 (sl) 2012-12-31
AU2007335663B2 (en) 2011-12-15
US20100173944A1 (en) 2010-07-08
JP5097126B2 (ja) 2012-12-12
KR20090101890A (ko) 2009-09-29
JPWO2008075462A1 (ja) 2010-04-08
EP2103608A1 (en) 2009-09-23
CN101553480B (zh) 2013-06-05
AU2007335663A1 (en) 2008-06-26
CA2671949A1 (en) 2008-06-26
BRPI0720539A2 (pt) 2014-01-07

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