KR100772210B1 - Stable Toothpaste Composition - Google Patents

Abstract

A stable tooth-foam composition is provided to secure the stability under various storage conditions, specifically at a temperature of less than 8 deg.C, have good taste and foam generating capability adequate for brushing teeth. A tooth-foam composition comprises 0.5-10 wt.% of sodium lauroyl sarcosinate as a surfactant acting as a foam generating agent and a cleansing agent; 0.1-10 wt.% of polyoxyethylene hydrogenated castor oil as an emulsifying agent; and 0.1-10 wt.% of polyoxyl hydrogenated castor oil as an emulsifying agent. The composition further comprises D-sorbitol solution, ethanol or a mixture thereof.

Description

Stable tooth-foam composition for brushing teeth

The present invention relates to a foam toothpaste composition for cleaning the teeth used in the form of foam through the foaming device, and more particularly to a foam toothpaste composition with improved stability in various distribution and storage conditions.

Toothpaste products include powdered toothpaste, creamy toothpaste, mouthwash, etc. in powder form, paste form or liquid form. Toothpaste in the form of paste other than paste paste easily adheres to toothbrush. It was not practical because of its use and was not widely used. Therefore, paste-type toothpaste is the most widely used, but most paste-type toothpaste contains a large amount of abrasives to give tooth surface gloss and remove plaque, which may damage the enamel surface. There are disadvantages.

As a new type of toothpaste with improved disadvantages, foam toothpaste, a tooth cleaner used in the form of foam, has been studied. Foam toothpaste not only adheres easily to toothbrushes, but also eliminates the inconvenience of liquid-type toothpaste that is inconvenient to use by adhering to powder-type toothpaste or toothbrush that does not foam, and also uses abrasives unlike paste-type toothpaste. There is an advantage that can be prevented by enamel damage of the tooth, there is an advantage that can be used safely and conveniently.

Korean Patent Laid-Open Publication No. 2002-0024967 discloses such a foam toothpaste, and includes sodium lauryl sulfate and polyoxyethylene sorbitan monooleate as surfactants; Fluorine compounds as caries preventive agents; Menthol as coolant; Spices; antiseptic; Sweeteners; Ethanol as a solvent; And a foam toothpaste composition containing purified water as a diluent. However, the foam toothpaste composition of the patent has a bad taste, precipitation of sodium lauryl sulfate, which is a surfactant included in the composition during product distribution and low temperature storage, precipitates, resulting in the cleaning power and activity (medical) which is a function of sodium lauryl sulfate. There is a disadvantage in that the function of dispersing the component is reduced, thereby reducing the efficacy as a toothpaste.

Accordingly, the technical problem to be achieved by the present invention is to provide a foam toothpaste composition having various storage conditions, in particular, stability at a low temperature of 8 ° C or less, good taste, and foaming ability suitable for tooth cleaning.

In order to achieve the above technical problem, the present invention is a sodium lauroyl sarcosinate (surfactant) that acts as a foaming agent and detergent in the foam toothpaste composition used in the foam form (sodium lauroyl sarcosinate); Polyoxyethylene hydrogenated castor oil which is an emulsifier; And it provides a foam toothpaste composition comprising a polyoxyl hydrogenated castor oil (emulsifier).

Preferably, the present invention, the foam toothpaste composition is 0.5-10% by weight sodium lauroyl sarcosinate relative to the total weight of the composition; 0.1-10% by weight of polyoxyethylene hydrogenated castor oil; And 0.1-10% by weight of polyoxyl hydrogenated castor oil.

More preferably, the present invention provides a foam toothpaste composition, wherein in the foam toothpaste composition, polyoxyethylene hydrogenated castor oil is polyoxyethylene hydrogenated castor oil 60, and polyoxyl hydrogenated castor oil is polyoxyl 40 hydrogenated castor oil.

More preferably, the present invention, the foam toothpaste composition 1-4% by weight sodium lauroyl sarcosinate relative to the total weight of the composition; Polyoxyethylene hydrogenated castor oil 60 1-3 wt%; And 0.5-1.8% by weight of polyoxyl 40 hydrogenated castor oil.

The present invention also provides a foam toothpaste composition, characterized in that the foam toothpaste composition further comprises a D-soribitol solution, ethanol or a mixture thereof as a solvent or a solvent.

Hereinafter, the foam toothpaste composition of the present invention will be described in more detail.

The foam toothpaste composition of the present invention includes sodium lauroyl sarcosinate, which is a surfactant, as a component that plays a role of foaming and cleaning. The use of sodium lauryl sulfate, a surfactant commonly used in cosmetic compositions as a foaming agent and cleaning agent, results in very low stability at low temperatures, and this problem can be overcome by using sodium lauroyl sarcosinate instead of sodium lauryl sulfate. have. However, when sodium lauroyl sarcosinate is used, the emulsifying power is lowered, and thus the stability of the composition is reduced. This problem can be solved by including polyoxyethylene hydrogenated castor oil and polyoxyl hydrogenated castor oil, which will be described later, together with the foam toothpaste composition.

In the foam toothpaste composition of the present invention, the content of sodium lauroyl sarcosinate is preferably 0.5-10% by weight, more preferably 1-4% by weight, based on the total weight of the foam toothpaste composition. If sodium lauroyl sarcosinate is contained in less than 0.5% by weight, the amount of foam decreases and the cleaning power is reduced. If it contains more than 10% by weight, the amount of foam is increased during tooth cleaning. Rejection may occur. Taking into account the taste, foaming power, etc., the content is more preferably 1-4% by weight.

The foam toothpaste composition of the present invention includes a polyoxyethylene hydrogenated castor oil and a polyoxyl hydrogenated castor oil which are emulsifiers to supplement the emulsifying power of sodium lauroyl sarcosinate. If only one emulsifier of polyoxyethylene hydrogenated castor oil and polyoxyl hydrogenated castor oil is used, the foam toothpaste composition is unstable, such as separation of an aqueous phase and an oil phase.

Depending on the number of polyoxyethylene units added to the polyoxyethylene hydrogenated castor oil, the polyoxyethylene hydrogenated castor oil 40, the polyoxyethylene hydrogenated castor oil 50, the polyoxyxylene hydrogenated castor oil 60, the polyoxyethylene hydrogenated castor oil 80, etc. And polyoxyethylene hydrogenated castor oil 60 is most preferred. As such polyoxyethylene hydrogenated castor oil 60, Emalex HC-60 ™ (Nihon Emulsion, Japan) may be used, but is not limited thereto.

Polyoxyl hydrogenated castor oil, polyoxyl 35 hydrogenated castor oil, polyoxyl 25 hydrogenated castor oil, polyoxyl 60 hydrogenated castor oil, etc., depending on the number of moles of ethylene oxide used per mol of hydrogenated castor oil Although polyoxyl 40 hydrogenated castor oil may be used, most preferred. As such polyoxyl 40 hydrogenated castor oil, Cremophor RH 40 ™ (BASF, Germany) may be used, but is not limited thereto.

The content of such polyoxyethylene hydrogenated castor oil and polyoxyl hydrogenated castor oil is preferably 0.1-10% by weight. If it is contained less than 0.1% by weight, it is not possible to ensure the stability of the foam toothpaste composition, when contained in more than 10% by weight there is a problem that the soap taste is too strong and the marketability is poor. In consideration of taste and stability, the content of polyoxyethylene hydrogenated castor oil and polyoxyl hydrogenated castor oil is more preferably 1-3% by weight and 0.5-1.8% by weight, respectively.

Preferably, the foam toothpaste composition of the present invention comprises a D-sorbitol solution (70% by weight aqueous solution), ethanol or a mixture thereof as a solvent or a solvent, and the D-sorbitol solution is 20-50% by weight relative to the total weight of the foam toothpaste composition. More preferably, ethanol is 0.5-5% by weight.

Foam toothpaste composition according to the present invention is a cavities prevention agent such as sodium fluoride, sodium monofluorophosphate, one fluoride; Periodontal disease prevention agents such as allantoin, allantoin chlorohydroxyaluminum, aminocaproic acid, pyridoxine hydrochloride, tocopherol acetate and the like; Preservatives such as sodium benzoate, methyl paraoxybenzoate, propyl paraoxybenzoate, sodium sodium oxybenzoate, and the like; Sweetening agents such as saccharin sodium, xylitol, aspartame and the like; pH regulators; It may further include a flavor, etc., the remaining amount is composed of purified water which is a diluent.

Hereinafter, examples and the like will be described in detail to help understand the present invention. However, embodiments according to the present invention can be modified in many different forms, the scope of the invention should not be construed as limited to the following examples. The embodiments of the present invention are provided to more completely explain the present invention to those skilled in the art.

<Production of Example 1-6 and Comparative Example>

In the case of Comparative Example and Example 1, after weighing each component, the caries preventive agent, periodontal disease preventive agent, surfactant, preservative, sweetener, pH adjuster and diluent are mixed and dispersed while stirring, and then by adding aroma and stirring Prepared.

In the case of Example 2-6, after weighing each component, the surfactant, caries preventive agent, periodontal disease preventive agent, solvent and diluent are mixed and dispersed while stirring, and the liquid which mixed the solvent agent and the preservative is added here, and disperse | distributes I was. Thereafter, the aroma and emulsifier were mixed and prepared by adding and stirring the stirred solution.

Configuration ingredient Comparative example Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Tooth decay prevention Sodium fluoride 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Periodontal Disease Prevention Allantoin 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Surfactants Sodium Lauryl Sulfate 3.0 - 3.0 - - - - Sodium lauroyl sarcosinate - - - 2.50 2.50 2.50 2.50 Emulsifier Polyoxyethylene Hydrogenated Castor Oil 60 - - 2.0 2.0 - - 2.0 Polyoxyl 40 Hydrogenated Castor Oil - - 1.30 1.30 - 1.30 - solvent D-sorbitol solution - - 34.0 34.0 34.0 34.0 34.0 Solvent ethanol - - 2.0 2.0 2.0 2.0 2.0 Preservative Sodium benzoate 0.10 0.10 - - - - - Paraoxybenzoic Acid Methyl - - 0.15 0.15 0.15 0.15 0.15 Sweetener Zaccarin Sodium 0.30 0.3 0.22 0.22 0.22 0.22 0.22 Xylitol - - 0.10 0.10 0.10 0.10 0.10 pH regulator Potassium Nitrate 0.5 0.5 - - - - - Spices incense 0.7 0.7 1.0 1.0 1.0 1.0 1.0 diluent Purified water Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount

In Table 1, Comparative Example is a foam toothpaste composition according to a known document, Example 1 is a foam toothpaste composition containing no surfactant and emulsifier, Example 2 includes a hydrogenated castor oil derivative which is an emulsifier, but surfactant Instead of sodium lauroyl sarcosinate of the present invention is a foam toothpaste composition containing sodium lauryl sulfate commonly used widely, Example 3 is one of the preferred embodiment according to the present invention, Example 4 is sodium lauroyl A foam toothpaste composition using cosinate but no hydrogenated castor oil derivative, and Examples 5 and 6 are foam toothpaste compositions including only one of polyoxyethylene hydrogenated castor oil and polyoxyl hydrogenated castor oil.

<Evaluation Evaluation of Example 1-6 and Comparative Example>

After preparing Examples 1-6 and Comparative Examples, it was visually evaluated for oil separation. The results are shown in Table 2 below.

Comparative example Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Whether oil is separated × ○ × × ○ ○ ○

In Table 2, ○ means that the oil component is separated, × means that the oil component is not separated.

As shown in Table 2, Comparative Examples and Examples 2 and 3 in which no separation of the aqueous phase and the oil phase occur, and Example 1 which is a prescription for clarifying the cause of precipitation although separation of the aqueous phase and the oil phase occur, which will be described later. Stability test was done. However, compared to sodium lauryl sulfate, the emulsification power of sodium lauroyl sarcosinate was reduced, so that the aqueous phase and the oil phase separated, and Example 4 and polyoxyethylene hydrogenated castor oil 60 or polyoxyl 40 hydrogenated castor oil alone were used. Examples 4 to 6 in which oil phase separation occurred were excluded from the stability test described later because the formulation was unstable.

<Stability Evaluation of Examples 1-3 and Comparative Examples>

The compositions of Examples 1-3 and Comparative Examples were stored at 8 ° C., room temperature and 50 ° C. and stability was evaluated. The results are shown in Table 3 below.

Condition Comparative example Example 1 1 day 1 month 3 months 1 day 1 month 3 months 8 ℃ freezer B, C, E B, C, E B, C, E A, D, E A, D, E A, D, E Room temperature A, C, E A, C, E A, C, E A, D, E A, D, E A, D, E 50 ℃ thermostat A, C, E A, C, E A, C, E A, D, E A, D, E A, D, E Condition Example 2 Example 3 1 day 1 month 3 months 1 day 1 month 3 months 8 ℃ freezer B, C, E B, C, E B, C, E A, C, E A, C, E A, C, E Room temperature A, C, E A, C, E A, C, E A, C, E A, C, E A, C, E 50 ℃ thermostat A, C, E A, C, E A, C, E A, C, E A, C, E A, C, E

In Table 3, A indicates that no precipitate is formed, B indicates that a precipitate is formed, C indicates that an oil component is not separated, D indicates that an oil component is separated, E indicates no discoloration, and F Slightly discolored, G means discolored.

In the long-term stability test results of Table 3, Comparative Example and Example 2 containing sodium lauryl sulfate were precipitated at 8 ° C. in one day, and the foam toothpaste composition was prepared in the same formulation as the comparative example except for sodium lauryl sulfate. In Example 1 prepared, it was judged that sodium lauryl sulfate caused the precipitation because no precipitation was formed in the stability test. Based on these results, instead of sodium lauryl sulfate, polyoxyethylene hydrogenated castor oil 60 and polyoxyl 40 hydrogenated castor oil, which are components to supplement the emulsifying power of foaming sodium lauroyl sarcosinate and sodium lauroyl sarcosinate, are used. In Example 3 prepared by the foam well generated during the separation did not occur in the separation of the water phase and oil phase, the stability test for 3 months does not occur precipitation at 8 ℃ conditions, discoloration occurs at 50 ℃ conditions Did not do it.

Preparation of Example 7-10

On the basis of Example 3, which solves the problem of the existing foam toothpaste, Table 4 was increased or decreased the content of sodium lauroyl sarcosinate in order to confirm the proper amount of surfactant through the sensory evaluation of the amount of foam and taste felt in the mouth. Prepared and tested by the prescription. To prepare Example 7-10 in the same manner as in Example 3 according to the ingredients and contents of Table 4.

Configuration Component (Unit: Mass%) Example 7 Example 8 Example 9 Example 10 Tooth decay prevention Sodium fluoride 0.1 0.1 0.1 0.1 Periodontal Disease Prevention Allantoin 0.05 0.05 0.05 0.05 Surfactants Sodium lauroyl sarcosinate 0.5 2.5 5.0 10.0 Emulsifier Polyoxyethylene Hydrogenated Castor Oil 60 2.0 2.0 2.0 2.0 Polyoxyl 40 Hydrogenated Castor Oil 1.30 1.30 1.30 1.30 solvent D-sorbitol solution 34.0 34.0 34.0 34.0 Solvent ethanol 2.0 2.0 2.0 2.0 antiseptic Paraoxybenzoic Acid Methyl 0.15 0.15 0.15 0.15 Sweetener Zaccarin Sodium 0.22 0.22 0.22 0.22 Xylitol 0.10 0.10 0.10 0.10 Spices incense 1.0 1.0 1.0 1.0 diluent Purified water Remaining amount Remaining amount Remaining amount Remaining amount

<Evaluation of Example 7-10>

The foaming amount and taste of the foam toothpaste composition of Example 7-10 were evaluated and the results are shown in Table 5 below. Twenty healthy adults were evaluated. In the case of the amount of foam, the amount of foam of each composition was comparatively evaluated. In the case of taste, the degree of soap taste was divided into three stages.

Example 7 Example 8 Example 9 Example 10 Status display A, E B, E C, F D, F

In Table 5, A denotes 'low bubble', B denotes 'good bubble', C denotes 'a bit high', D denotes 'high bubble', and E denotes 'good' , F stands for 'weak soapy taste', and G stands for 'strong soapy taste'.

According to Table 5, which is a result of sensory evaluation on the amount of foam and taste that varies depending on the content of the sodium lauroyl sarcosinate, which is a surfactant, the amount of foam is small, so the cleaning power is reduced, If the amount is too high, the amount of foam in the mouth increases, which is not only inconvenient in use, but also when the soap taste is strong and exceeds 10% by weight, a strong soapy taste results in a taste rejection, thereby degrading the value as a product. In the foam toothpaste composition according to the present invention, the content of sodium lauroyl sarcosinate was most preferably 1 to 4% by weight based on the total weight of the composition.

Preparation of Example 11-15

On the basis of Example 3, which solves the problems of the existing foam toothpaste, prepared by the formulation of Table 6 in which the contents of each of the emulsifiers were changed in order to confirm the proper amount of the emulsifier through the sensory evaluation of the amount of foam and taste felt in the mouth. Tested. Example 11-15 was prepared in the same manner as in Example 3, according to the ingredients and contents of Table 6 below.

Configuration Component (Unit: Mass%) Example 11 Example 12 Example 13 Example 14 Example 15 Tooth decay prevention Sodium fluoride 0.1 0.1 0.1 0.1 0.1 Periodontal Disease Prevention Allantoin 0.05 0.05 0.05 0.05 0.05 Surfactants Sodium lauroyl sarcosinate 2.5 2.5 2.5 2.5 2.5 Emulsifier Polyoxyethylene Hydrogenated Castor Oil 60 10.0 5.0 2.0 3.0 0 Polyoxyl 40 Hydrogenated Castor Oil 0 3.0 1.3 5.0 10.0 solvent D-sorbitol solution 34.0 34.0 34.0 34.0 34.0 Solvent ethanol 2.0 2.0 2.0 2.0 2.0 antiseptic Paraoxybenzoic Acid Methyl 0.15 0.15 0.15 0.15 0.15 Sweetener Zaccarin Sodium 0.22 0.22 0.22 0.22 0.22 Xylitol 0.10 0.10 0.10 0.10 0.10 Spices incense 1.0 1.0 1.0 1.0 1.0 diluent Purified water Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount

<Evaluation of Example 11-15>

The taste of the foam toothpaste composition of Example 11-15 was evaluated and the results are shown in Table 7 below. Twenty healthy adults were evaluated, and the degree of soap taste was divided into three stages.

Example 11 Example 12 Example 13 Example 14 Example 15 Status display C B A B C

In Table 7, A denotes 'good taste', B denotes 'weak soap taste', and C denotes 'strong soap taste'.

According to the results of sensory evaluation of the taste in the mouth according to the increase and decrease of the polyoxyethylene hydrogenated castor oil 60 and polyoxyl 40 hydrogenated castor oil content as emulsifiers, the higher the content of the two emulsifiers, the stronger the soap taste. When the content of the emulsifier exceeds 10% by weight or the total content of the two emulsifiers exceeds 10% by weight, the strong soapy taste results in a taste rejection, which lowers the value as a product. In addition, as shown in Table 7, the content of polyoxyethylene hydrogenated castor oil 60 to the total weight of the composition is most preferably 1 to 3% by weight based on the taste, the polyoxyl 40 hydrogenated castor oil is 0.5 to 1.8 % By weight is most preferred.

As a result, Example 3, Example 8 and Example 13, which were the same prescription, were not only stable under various conditions in long-term storage, but also had a good amount of foam and taste, showing excellent results as a product.

As such, the foam toothpaste composition according to the present invention is not only stable under various storage conditions, but also has a good taste and produces an amount of foam suitable for tooth cleaning.

Claims (5)

In the foam toothpaste composition used in the form of a foam, Sodium lauroyl sarcosinate, a surfactant that acts as a foaming agent and detergent; Polyoxyethylene hydrogenated castor oil which is an emulsifier; And polyoxyl hydrogenated castor oil which is an emulsifier. The method of claim 1, The composition comprises 0.5-10% by weight of sodium lauroyl sarcosinate relative to the total weight of the composition; 0.1-10% by weight of polyoxyethylene hydrogenated castor oil; And 0.1-10% by weight of polyoxyl hydrogenated castor oil. The method of claim 1, The polyoxyethylene hydrogenated castor oil is polyoxyethylene hydrogenated castor oil 60, polyoxyl hydrogenated castor oil is a foam toothpaste composition, characterized in that the polyoxyl 40 hydrogenated castor oil. The method of claim 3, The composition comprises 1-4% by weight of sodium lauroyl sarcosinate relative to the total weight of the composition; Polyoxyethylene hydrogenated castor oil 60 1-3 wt%; And 0.5-1.8% by weight of polyoxyl 40 hydrogenated castor oil. The method according to any one of claims 1 to 4, The composition is a foam toothpaste composition, characterized in that it further comprises a D-sorbitol solution, ethanol or a mixture thereof.