JPS643190A - Damavaricin fc derivative - Google Patents
Damavaricin fc derivativeInfo
- Publication number
- JPS643190A JPS643190A JP62158560A JP15856087A JPS643190A JP S643190 A JPS643190 A JP S643190A JP 62158560 A JP62158560 A JP 62158560A JP 15856087 A JP15856087 A JP 15856087A JP S643190 A JPS643190 A JP S643190A
- Authority
- JP
- Japan
- Prior art keywords
- expressed
- formula
- damavaricin
- ethyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229930186463 Damavaricin Natural products 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- -1 silver ions Chemical class 0.000 abstract 2
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 abstract 2
- 230000007059 acute toxicity Effects 0.000 abstract 1
- 231100000403 acute toxicity Toxicity 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000004332 silver Substances 0.000 abstract 1
- 229910001923 silver oxide Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
NEW MATERIAL:A compound expressed by formula I [A is expressed by formula II (B is methylene, O or S; l is 0 or 1; m and n are 0W6; R1 and R2 are methyl or ethyl; R3 is 1W5C alkyl; R4 is H, methyl or ethyl)].
EXAMPLE: 19-O-Trimethylsilylmethyldamavaricin Fc.
USE: An antimicrobial and antiviral agent having low acute toxicity and high intracorporeal absorbability.
PREPARATION: For example, a halide expressed by formula III (X is halogen, such as Cl, Br or I) is reacted with damavaricin Fc in the presence of silver ions, such as silver oxide, in a solvent, such as methanol, at 0W80°C.
COPYRIGHT: (C)1989,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62158560A JPS643190A (en) | 1987-06-25 | 1987-06-25 | Damavaricin fc derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62158560A JPS643190A (en) | 1987-06-25 | 1987-06-25 | Damavaricin fc derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH013190A JPH013190A (en) | 1989-01-06 |
| JPS643190A true JPS643190A (en) | 1989-01-06 |
Family
ID=15674372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62158560A Pending JPS643190A (en) | 1987-06-25 | 1987-06-25 | Damavaricin fc derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS643190A (en) |
-
1987
- 1987-06-25 JP JP62158560A patent/JPS643190A/en active Pending
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