JO3567B1 - جزيئات جسم مضاد لـ tim-3 واستخداماتها - Google Patents

جزيئات جسم مضاد لـ tim-3 واستخداماتها

Info

Publication number
JO3567B1
JO3567B1 JOP/2015/0017A JOP20150017A JO3567B1 JO 3567 B1 JO3567 B1 JO 3567B1 JO P20150017 A JOP20150017 A JO P20150017A JO 3567 B1 JO3567 B1 JO 3567B1
Authority
JO
Jordan
Prior art keywords
tim
antibody molecules
cancerous
disorders
treat
Prior art date
Application number
JOP/2015/0017A
Other languages
English (en)
Inventor
A Blattler Walter
James Freeman Gordon
J Hicklin Daniel
T Umetsu Dale
S Harris Alan
Marie Mataraza Jennifer
Xu Fangmin
Vasquez Maximiliano
H Dekruyff Rosemarie
Hu Tiancen
A Taraszka John
Brannetti Barbara
Pietzonka Thomas
Huber Thomas
Anne Sabatos-Peyton Catherine
Original Assignee
Novartis Ag
Dana Farber Cancer Inst Inc
Children’S Medical Center Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52478098&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3567(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Dana Farber Cancer Inst Inc, Children’S Medical Center Corp filed Critical Novartis Ag
Application granted granted Critical
Publication of JO3567B1 publication Critical patent/JO3567B1/ar

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/565—Complementarity determining region [CDR]
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
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  • Mycology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
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  • General Physics & Mathematics (AREA)
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  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
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  • Diabetes (AREA)
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Abstract

تم الكشف عن جزيئات جسم مضاد ترتبط بشكل خاص بـ TIM-3 . يمكن استخدام جزيئات الجسم المضاد لـ TIM-3 لمعالجة، الوقاية و/أو التشخيص المناعي، لسرطان، أو ظروف مُعدية و/أو اضطرابات.
JOP/2015/0017A 2014-01-31 2015-02-01 جزيئات جسم مضاد لـ tim-3 واستخداماتها JO3567B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461934469P 2014-01-31 2014-01-31
US201462094912P 2014-12-19 2014-12-19

Publications (1)

Publication Number Publication Date
JO3567B1 true JO3567B1 (ar) 2020-07-05

Family

ID=52478098

Family Applications (2)

Application Number Title Priority Date Filing Date
JOP/2015/0017A JO3567B1 (ar) 2014-01-31 2015-02-01 جزيئات جسم مضاد لـ tim-3 واستخداماتها
JOP/2020/0096A JOP20200096A1 (ar) 2014-01-31 2020-05-04 جزيئات جسم مضاد لـ tim-3 واستخداماتها

Family Applications After (1)

Application Number Title Priority Date Filing Date
JOP/2020/0096A JOP20200096A1 (ar) 2014-01-31 2020-05-04 جزيئات جسم مضاد لـ tim-3 واستخداماتها

Country Status (34)

Country Link
US (6) US9605070B2 (ar)
EP (3) EP4324518A3 (ar)
JP (3) JP6539667B2 (ar)
KR (2) KR20220028145A (ar)
CN (2) CN113896791A (ar)
AU (2) AU2015210750B2 (ar)
CA (1) CA2936863A1 (ar)
CL (1) CL2016001716A1 (ar)
CR (1) CR20160347A (ar)
CU (1) CU24427B1 (ar)
CY (1) CY1121893T1 (ar)
DK (1) DK3099717T3 (ar)
EA (1) EA201691556A1 (ar)
EC (1) ECSP16070447A (ar)
ES (2) ES2732901T3 (ar)
HR (1) HRP20191083T1 (ar)
HU (1) HUE045065T2 (ar)
IL (1) IL246693B2 (ar)
JO (2) JO3567B1 (ar)
LT (1) LT3099717T (ar)
ME (1) ME03489B (ar)
MX (2) MX375953B (ar)
MY (1) MY187296A (ar)
NZ (2) NZ722042A (ar)
PE (1) PE20170330A1 (ar)
PH (1) PH12016501482B1 (ar)
PL (1) PL3099717T3 (ar)
PT (1) PT3099717T (ar)
RS (1) RS59065B1 (ar)
SG (1) SG11201605627TA (ar)
SI (1) SI3099717T1 (ar)
TW (2) TWI686406B (ar)
UY (2) UY35973A (ar)
WO (1) WO2015117002A1 (ar)

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WO2015048312A1 (en) 2013-09-26 2015-04-02 Costim Pharmaceuticals Inc. Methods for treating hematologic cancers
PE20170255A1 (es) 2014-01-24 2017-03-22 Dana Farber Cancer Inst Inc Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas
HUE045065T2 (hu) 2014-01-31 2019-12-30 Novartis Ag TIM-3 antitest molekulák és felhasználásaik
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KR102442436B1 (ko) 2014-03-14 2022-09-15 노파르티스 아게 Lag-3에 대한 항체 분자 및 그의 용도
TW201613576A (en) 2014-06-26 2016-04-16 Novartis Ag Intermittent dosing of MDM2 inhibitor
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IL246693A0 (en) 2016-08-31
JP2017511687A (ja) 2017-04-27
EA201691556A1 (ru) 2016-12-30
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JP2019147809A (ja) 2019-09-05
CU24427B1 (es) 2019-06-04
AU2020227017B2 (en) 2022-09-15
US20150218274A1 (en) 2015-08-06
AU2015210750B2 (en) 2020-08-20
HRP20191083T1 (hr) 2019-09-20
SG11201605627TA (en) 2016-08-30
BR112016016436A2 (pt) 2017-12-12
EP4324518A2 (en) 2024-02-21
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CN106132991B (zh) 2021-07-02
PH12016501482A1 (en) 2016-08-22
EP4324518A3 (en) 2024-05-22
TWI769434B (zh) 2022-07-01
EP3099717A1 (en) 2016-12-07
UY35973A (es) 2015-08-31
KR102366218B1 (ko) 2022-02-23
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PT3099717T (pt) 2019-07-10
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