GB2546703A - Compounds - Google Patents
CompoundsInfo
- Publication number
- GB2546703A GB2546703A GB1707536.7A GB201707536A GB2546703A GB 2546703 A GB2546703 A GB 2546703A GB 201707536 A GB201707536 A GB 201707536A GB 2546703 A GB2546703 A GB 2546703A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- arsenosugar
- arsenobetaine
- analogues
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 title 1
- SPTHHTGLGVZZRH-UHFFFAOYSA-N Arsenobetaine Chemical compound C[As+](C)(C)CC([O-])=O SPTHHTGLGVZZRH-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 150000001495 arsenic compounds Chemical class 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229940093920 gynecological arsenic compound Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention relates to arsenic compounds, particularly arsenobetaine and arsenosugar analogues and derivatives and their use in therapy, particularly for the prevention and/or treatment of cancer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1418491.5A GB201418491D0 (en) | 2014-10-17 | 2014-10-17 | Compounds |
| PCT/EP2015/073974 WO2016059198A1 (en) | 2014-10-17 | 2015-10-16 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB201707536D0 GB201707536D0 (en) | 2017-06-28 |
| GB2546703A true GB2546703A (en) | 2017-07-26 |
Family
ID=52013185
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1418491.5A Ceased GB201418491D0 (en) | 2014-10-17 | 2014-10-17 | Compounds |
| GB1707536.7A Withdrawn GB2546703A (en) | 2014-10-17 | 2015-10-16 | Compounds |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1418491.5A Ceased GB201418491D0 (en) | 2014-10-17 | 2014-10-17 | Compounds |
Country Status (2)
| Country | Link |
|---|---|
| GB (2) | GB201418491D0 (en) |
| WO (1) | WO2016059198A1 (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006020048A2 (en) * | 2004-07-16 | 2006-02-23 | The Texas A & M University System | Compounds and methods for treatment of cancer |
-
2014
- 2014-10-17 GB GBGB1418491.5A patent/GB201418491D0/en not_active Ceased
-
2015
- 2015-10-16 GB GB1707536.7A patent/GB2546703A/en not_active Withdrawn
- 2015-10-16 WO PCT/EP2015/073974 patent/WO2016059198A1/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006020048A2 (en) * | 2004-07-16 | 2006-02-23 | The Texas A & M University System | Compounds and methods for treatment of cancer |
Non-Patent Citations (3)
| Title |
|---|
| "A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells", A.H. Van der Luit et al, Molecular Cancer Therapeutics, (2007), 6(8), 2337-2345 * |
| "Modulation of cell adhesion and viability of cultured murine bone marrow cells by arsenobetaine, a major organic arsenic compound in marine animals", T. Sakurai et al, British Journal of Pharmacology, 132(1), (2001), 143-150 * |
| "Novel therapeutic approach: Organic arsenical (melarsoprol) alone or with all-trans-retinoic acid markedly inhibit growth of human breast and prostate cancer cells in vitro and in vivo", K. Koshiuka et al, British Journal of Cancer, (2000), 82(2), 452-458 * |
Also Published As
| Publication number | Publication date |
|---|---|
| GB201707536D0 (en) | 2017-06-28 |
| WO2016059198A1 (en) | 2016-04-21 |
| GB201418491D0 (en) | 2014-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |