GB202402011D0 - A novel type of crispr/cas system - Google Patents
A novel type of crispr/cas systemInfo
- Publication number
- GB202402011D0 GB202402011D0 GBGB2402011.7A GB202402011A GB202402011D0 GB 202402011 D0 GB202402011 D0 GB 202402011D0 GB 202402011 A GB202402011 A GB 202402011A GB 202402011 D0 GB202402011 D0 GB 202402011D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- crispr
- cas system
- novel type
- novel
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2402011.7A GB202402011D0 (en) | 2024-02-14 | 2024-02-14 | A novel type of crispr/cas system |
| PCT/EP2024/074264 WO2025046062A1 (en) | 2023-08-31 | 2024-08-30 | A novel type of crispr/cas system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2402011.7A GB202402011D0 (en) | 2024-02-14 | 2024-02-14 | A novel type of crispr/cas system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB202402011D0 true GB202402011D0 (en) | 2024-03-27 |
Family
ID=90354784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB2402011.7A Ceased GB202402011D0 (en) | 2023-08-31 | 2024-02-14 | A novel type of crispr/cas system |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB202402011D0 (en) |
| WO (1) | WO2025046062A1 (en) |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014121222A1 (en) * | 2013-02-01 | 2014-08-07 | The University Of Western Ontario | Endonuclease for genome editing |
| CA2942245C (en) | 2014-03-12 | 2021-11-02 | Yeda Research And Development Co. Ltd. | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns |
| JP7095993B2 (en) | 2015-03-02 | 2022-07-05 | シンロジック オペレーティング カンパニー インコーポレイテッド | Bacteria engineered for the treatment of diseases that benefit from reduced gastrointestinal inflammation and / or enhanced gastrointestinal mucosal barrier |
| EP3711488A1 (en) | 2015-05-06 | 2020-09-23 | Snipr Technologies Limited | Altering microbial populations & modifying microbiota |
| AU2016276973B2 (en) | 2015-06-10 | 2022-09-01 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders involving the catabolism of a branched chain amino acid |
| US10300043B2 (en) | 2015-08-12 | 2019-05-28 | Mayo Foundation For Medical Education And Research | Method for treating a gastrointestinal disorder in a mammal using bacteroides thetaiotaomicron and compositions thereof |
| EP3368696A1 (en) | 2015-10-30 | 2018-09-05 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| WO2017123418A1 (en) | 2016-01-11 | 2017-07-20 | Synlogic, Inc. | Bacteria engineered to treat metabolic diseases |
| EP3411051A2 (en) | 2016-02-04 | 2018-12-12 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| JP2020527025A (en) | 2017-07-12 | 2020-09-03 | シンロジック オペレーティング カンパニー インコーポレイテッド | Microorganisms programmed to produce immune modulators and anti-cancer therapeutic agents in tumor cells |
| US20220307001A1 (en) | 2018-02-27 | 2022-09-29 | President And Fellows Of Harvard College | Evolved cas9 variants and uses thereof |
| JP2021525760A (en) | 2018-06-02 | 2021-09-27 | シンロジック オペレーティング カンパニー インコーポレイテッド | Bacteria engineered to treat liver disease |
| WO2020097424A1 (en) | 2018-11-08 | 2020-05-14 | Synlogic Operating Company, Inc. | Combination therapies of microorganisms and immune modulators for use in treating cancer |
| US12421518B2 (en) | 2018-12-10 | 2025-09-23 | Tenza, Inc. | Methods and compositions for treating hyperoxaluria |
| WO2020181178A1 (en) | 2019-03-06 | 2020-09-10 | The Broad Institute, Inc. | T:a to a:t base editing through thymine alkylation |
| WO2020181195A1 (en) | 2019-03-06 | 2020-09-10 | The Broad Institute, Inc. | T:a to a:t base editing through adenine excision |
| WO2020181180A1 (en) | 2019-03-06 | 2020-09-10 | The Broad Institute, Inc. | A:t to c:g base editors and uses thereof |
| WO2020181202A1 (en) | 2019-03-06 | 2020-09-10 | The Broad Institute, Inc. | A:t to t:a base editing through adenine deamination and oxidation |
| WO2020181193A1 (en) | 2019-03-06 | 2020-09-10 | The Broad Institute, Inc. | T:a to a:t base editing through adenosine methylation |
| GB201906668D0 (en) | 2019-05-12 | 2019-06-26 | Folium Food Science Ltd | Antibacterial agents |
| CA3140174A1 (en) | 2019-05-13 | 2020-11-19 | Synlogic Operating Company, Inc. | Synergistic combinations of arginine-producing bacteria and/or ammonia-consuming bacteria and checkpoint inhibitors and methods of use thereof |
| US20240247228A1 (en) | 2019-06-13 | 2024-07-25 | Novome Biotechnologies, Inc. | Biologically contained bacteria and uses thereof |
| JP2022537214A (en) | 2019-06-21 | 2022-08-24 | ギンゴー バイオワークス， インコーポレイテッド | Enzyme biosynthesis for use in the treatment of maple syrup urine disease (MSUD) |
| BR112022013867A2 (en) | 2020-01-14 | 2022-09-13 | Synlogic Operating Co Inc | BACTERIA MANIPULATED TO TREAT DISORDERS IN WHICH OXALATE IS HARMFUL |
| WO2021146394A1 (en) | 2020-01-14 | 2021-07-22 | Synlogic Operating Company, Inc. | Optimized bacteria engineered to treat disorders involving the catabolism of leucine, isoleucine, and/or valine |
| EP4103690A4 (en) | 2020-02-12 | 2024-03-06 | Synlogic Operating Company, Inc. | Recombinant bacteria engineered to treat diseases associated with methionine metabolism and methods of use thereof |
| US20230105474A1 (en) | 2020-02-25 | 2023-04-06 | Synlogic Operating Company, Inc. | Recombinant bacteria engineered to treat diseases associated with uric acid and methods of use thereof |
| US20230174926A1 (en) | 2020-03-17 | 2023-06-08 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders involving the catabolism of leucine |
| BR112022018571A2 (en) | 2020-03-20 | 2022-11-01 | Synlogic Operating Co Inc | MICRO-ORGANISMS MANIPULATED TO REDUCE HYPERPHENYLALANINEMIA |
| WO2021242897A1 (en) | 2020-05-26 | 2021-12-02 | Synlogic Operating Company, Inc. | Recombinant bacteria for production of indole-3-acetic acid (iaa) and uses thereof |
| US20230332164A1 (en) | 2020-09-30 | 2023-10-19 | Synlogic Operating Company, Inc. | Bacteria engineered to secrete active proteins |
| CA3197414A1 (en) * | 2020-11-04 | 2022-05-12 | Brent E. STEAD | Gene editing with a modified endonuclease |
| CN116847860A (en) | 2020-12-31 | 2023-10-03 | 同生运营公司 | Microorganisms engineered to mitigate hyperphenylalaninemia |
| WO2022150779A1 (en) | 2021-01-11 | 2022-07-14 | Synlogic Operating Company, Inc. | Methods of treating cancer using recombinant microorganisms expressing a sting agonist |
| WO2022169909A2 (en) | 2021-02-02 | 2022-08-11 | Novome Biotechnologies, Inc. | Methods and compositions for treating disorders associated with bile acids |
| WO2022204406A1 (en) | 2021-03-24 | 2022-09-29 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders in which oxalate is detrimental |
| EP4323385A1 (en) | 2021-04-13 | 2024-02-21 | Synlogic Operating Company, Inc. | Bacteria engineered to secrete active proteins |
| CN116200368A (en) * | 2021-11-30 | 2023-06-02 | 上海科技大学 | Novel genome editing system based on C2C9 nuclease and application thereof |
| WO2023225667A2 (en) | 2022-05-20 | 2023-11-23 | Synlogic Operating Company, Inc. | Recombinant bacteria for production of indole-3-acetic acid (iaa) and uses thereof |
-
2024
- 2024-02-14 GB GBGB2402011.7A patent/GB202402011D0/en not_active Ceased
- 2024-08-30 WO PCT/EP2024/074264 patent/WO2025046062A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025046062A1 (en) | 2025-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |