GB202311280D0 - Orexin receptor antagonists - Google Patents

Orexin receptor antagonists

Info

Publication number
GB202311280D0
GB202311280D0 GBGB2311280.8A GB202311280A GB202311280D0 GB 202311280 D0 GB202311280 D0 GB 202311280D0 GB 202311280 A GB202311280 A GB 202311280A GB 202311280 D0 GB202311280 D0 GB 202311280D0
Authority
GB
United Kingdom
Prior art keywords
receptor antagonists
orexin receptor
orexin
antagonists
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2311280.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bial Portela and Cia SA
Original Assignee
Bial Portela and Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Portela and Cia SA filed Critical Bial Portela and Cia SA
Priority to GBGB2311280.8A priority Critical patent/GB202311280D0/en
Publication of GB202311280D0 publication Critical patent/GB202311280D0/en
Priority to PCT/PT2024/050028 priority patent/WO2025023851A1/en
Priority to EP24754432.3A priority patent/EP4688154A1/en
Priority to CN202480048220.3A priority patent/CN121752559A/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
GBGB2311280.8A 2023-07-21 2023-07-21 Orexin receptor antagonists Ceased GB202311280D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GBGB2311280.8A GB202311280D0 (en) 2023-07-21 2023-07-21 Orexin receptor antagonists
PCT/PT2024/050028 WO2025023851A1 (en) 2023-07-21 2024-07-22 Morpholine orexin receptor antagonists
EP24754432.3A EP4688154A1 (en) 2023-07-21 2024-07-22 Morpholine orexin receptor antagonists
CN202480048220.3A CN121752559A (en) 2023-07-21 2024-07-22 Morpholino orexin receptor antagonists

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2311280.8A GB202311280D0 (en) 2023-07-21 2023-07-21 Orexin receptor antagonists

Publications (1)

Publication Number Publication Date
GB202311280D0 true GB202311280D0 (en) 2023-09-06

Family

ID=87852053

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2311280.8A Ceased GB202311280D0 (en) 2023-07-21 2023-07-21 Orexin receptor antagonists

Country Status (4)

Country Link
EP (1) EP4688154A1 (en)
CN (1) CN121752559A (en)
GB (1) GB202311280D0 (en)
WO (1) WO2025023851A1 (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4246490B2 (en) * 2000-11-28 2009-04-02 スミスクライン ビーチャム ピー エル シー Morpholine derivatives as antagonists of orexin receptors
IL158463A0 (en) 2001-05-05 2004-05-12 Smithkline Beecham Plc N-aroyl cyclic amines
BR0210609A (en) * 2001-06-28 2004-07-20 Smithkline Beecham Plc Cyclically n-aroyl amine derivatives as orexin receptor antagonists
TWI565703B (en) 2011-11-08 2017-01-11 艾克泰聯製藥有限公司 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-yl)pyridinium derivatives
WO2015095276A1 (en) * 2013-12-19 2015-06-25 Merck Sharp & Dohme Corp. Hiv protease inhibitors
GB201601703D0 (en) 2016-01-29 2016-03-16 C4X Discovery Ltd Therapeutic compounds
MX2018009656A (en) 2016-02-12 2019-02-20 Astrazeneca Ab Halo-substituted piperidines as orexin receptor modulators.
CN114286675A (en) 2019-06-04 2022-04-05 海格生物科学有限责任公司 Imidazole derivatives, compositions and methods as orexin antagonists
US20220315602A1 (en) 2019-06-04 2022-10-06 Hager Biosciences, Llc Pyrazole and imidazole derivatives, compositions and methods as orexin antagonists

Also Published As

Publication number Publication date
EP4688154A1 (en) 2026-02-11
WO2025023851A1 (en) 2025-01-30
CN121752559A (en) 2026-03-27

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)