GB202311280D0 - Orexin receptor antagonists - Google Patents
Orexin receptor antagonistsInfo
- Publication number
- GB202311280D0 GB202311280D0 GBGB2311280.8A GB202311280A GB202311280D0 GB 202311280 D0 GB202311280 D0 GB 202311280D0 GB 202311280 A GB202311280 A GB 202311280A GB 202311280 D0 GB202311280 D0 GB 202311280D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- receptor antagonists
- orexin receptor
- orexin
- antagonists
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2311280.8A GB202311280D0 (en) | 2023-07-21 | 2023-07-21 | Orexin receptor antagonists |
| PCT/PT2024/050028 WO2025023851A1 (en) | 2023-07-21 | 2024-07-22 | Morpholine orexin receptor antagonists |
| EP24754432.3A EP4688154A1 (en) | 2023-07-21 | 2024-07-22 | Morpholine orexin receptor antagonists |
| CN202480048220.3A CN121752559A (en) | 2023-07-21 | 2024-07-22 | Morpholino orexin receptor antagonists |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2311280.8A GB202311280D0 (en) | 2023-07-21 | 2023-07-21 | Orexin receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB202311280D0 true GB202311280D0 (en) | 2023-09-06 |
Family
ID=87852053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB2311280.8A Ceased GB202311280D0 (en) | 2023-07-21 | 2023-07-21 | Orexin receptor antagonists |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP4688154A1 (en) |
| CN (1) | CN121752559A (en) |
| GB (1) | GB202311280D0 (en) |
| WO (1) | WO2025023851A1 (en) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4246490B2 (en) * | 2000-11-28 | 2009-04-02 | スミスクライン ビーチャム ピー エル シー | Morpholine derivatives as antagonists of orexin receptors |
| IL158463A0 (en) | 2001-05-05 | 2004-05-12 | Smithkline Beecham Plc | N-aroyl cyclic amines |
| BR0210609A (en) * | 2001-06-28 | 2004-07-20 | Smithkline Beecham Plc | Cyclically n-aroyl amine derivatives as orexin receptor antagonists |
| TWI565703B (en) | 2011-11-08 | 2017-01-11 | 艾克泰聯製藥有限公司 | 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-yl)pyridinium derivatives |
| WO2015095276A1 (en) * | 2013-12-19 | 2015-06-25 | Merck Sharp & Dohme Corp. | Hiv protease inhibitors |
| GB201601703D0 (en) | 2016-01-29 | 2016-03-16 | C4X Discovery Ltd | Therapeutic compounds |
| MX2018009656A (en) | 2016-02-12 | 2019-02-20 | Astrazeneca Ab | Halo-substituted piperidines as orexin receptor modulators. |
| CN114286675A (en) | 2019-06-04 | 2022-04-05 | 海格生物科学有限责任公司 | Imidazole derivatives, compositions and methods as orexin antagonists |
| US20220315602A1 (en) | 2019-06-04 | 2022-10-06 | Hager Biosciences, Llc | Pyrazole and imidazole derivatives, compositions and methods as orexin antagonists |
-
2023
- 2023-07-21 GB GBGB2311280.8A patent/GB202311280D0/en not_active Ceased
-
2024
- 2024-07-22 CN CN202480048220.3A patent/CN121752559A/en active Pending
- 2024-07-22 WO PCT/PT2024/050028 patent/WO2025023851A1/en active Pending
- 2024-07-22 EP EP24754432.3A patent/EP4688154A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4688154A1 (en) | 2026-02-11 |
| WO2025023851A1 (en) | 2025-01-30 |
| CN121752559A (en) | 2026-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |