FR2548664B1 - 7- (PYRROL-L-YL) DERIVATIVES OF L-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXYLIC ACIDS AND L-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDINE) ) -3-SUBSTITUTED CARBOXYLICS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS - Google Patents

7- (PYRROL-L-YL) DERIVATIVES OF L-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXYLIC ACIDS AND L-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDINE) ) -3-SUBSTITUTED CARBOXYLICS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

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Publication number
FR2548664B1
FR2548664B1 FR8311250A FR8311250A FR2548664B1 FR 2548664 B1 FR2548664 B1 FR 2548664B1 FR 8311250 A FR8311250 A FR 8311250A FR 8311250 A FR8311250 A FR 8311250A FR 2548664 B1 FR2548664 B1 FR 2548664B1
Authority
FR
France
Prior art keywords
dihydro
ethyl
oxoquinolein
naphtyridine
carboxylics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8311250A
Other languages
French (fr)
Other versions
FR2548664A1 (en
Inventor
Jose Esteve Soler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Provesan SA
Original Assignee
Provesan SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Provesan SA filed Critical Provesan SA
Priority to FR8311250A priority Critical patent/FR2548664B1/en
Priority to FR8402145A priority patent/FR2559484B2/en
Priority to AU29425/84A priority patent/AU564326B2/en
Priority to US06/622,647 priority patent/US4552882A/en
Priority to ZA844693A priority patent/ZA844693B/en
Priority to CA000457471A priority patent/CA1256876A/en
Priority to ES533749A priority patent/ES8503335A1/en
Priority to MX201827A priority patent/MX156436A/en
Priority to DE8484401391T priority patent/DE3471934D1/en
Priority to EP84401391A priority patent/EP0134165B1/en
Priority to AT84401391T priority patent/ATE34982T1/en
Priority to GR75174A priority patent/GR81646B/el
Priority to PL1984248545A priority patent/PL143730B1/en
Priority to IN536/DEL/84A priority patent/IN161611B/en
Priority to RO115120A priority patent/RO88915B/en
Priority to NO842717A priority patent/NO163329C/en
Priority to JP59138851A priority patent/JPS6036482A/en
Priority to BR8403342A priority patent/BR8403342A/en
Priority to DD84264967A priority patent/DD223150A5/en
Priority to PT78854A priority patent/PT78854B/en
Priority to SU843759901A priority patent/SU1322980A3/en
Priority to DK331384A priority patent/DK163126C/en
Priority to HU842641A priority patent/HU189916B/en
Priority to CS845285A priority patent/CS244139B2/en
Priority to KR1019840003918A priority patent/KR880002355B1/en
Priority to YU1190/84A priority patent/YU43577B/en
Publication of FR2548664A1 publication Critical patent/FR2548664A1/en
Application granted granted Critical
Publication of FR2548664B1 publication Critical patent/FR2548664B1/en
Priority to HK104/91A priority patent/HK10491A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR8311250A 1983-07-06 1983-07-06 7- (PYRROL-L-YL) DERIVATIVES OF L-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXYLIC ACIDS AND L-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDINE) ) -3-SUBSTITUTED CARBOXYLICS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS Expired FR2548664B1 (en)

Priority Applications (27)

Application Number Priority Date Filing Date Title
FR8311250A FR2548664B1 (en) 1983-07-06 1983-07-06 7- (PYRROL-L-YL) DERIVATIVES OF L-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXYLIC ACIDS AND L-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDINE) ) -3-SUBSTITUTED CARBOXYLICS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR8402145A FR2559484B2 (en) 1983-07-06 1984-02-13 NEW DERIVATIVE 7- (PYRROL-1-YL) OF 1-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDIN) -3-CARBOXYLIC ACID, ITS PREPARATION AND ITS APPLICATION AS A MEDICAMENT
AU29425/84A AU564326B2 (en) 1983-07-06 1984-06-15 1,4-dihydro-quinoline and 1,4-dihydro-1,8-naphthyridine derivatives
US06/622,647 US4552882A (en) 1983-07-06 1984-06-20 7-(1-Pyrrolyl) derivatives of 1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids and 1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids and their use as antimicrobial agents
ZA844693A ZA844693B (en) 1983-07-06 1984-06-21 7-(1-pyrrolyl)derivatives of substituted 1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids and substituted 1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids,their preparation and their application as drugs
CA000457471A CA1256876A (en) 1983-07-06 1984-06-26 7-(1-pyrrolyl) derivatives of substituted 1-ethyl-1,4- dihydro-4-oxoquinoline-3-carboxylic acids and substituted 1-ethyl-1,4-dihydro-4-oxo-1,8- naphthyridine-3-carboxylic acids,their preparation and their application as drugs
ES533749A ES8503335A1 (en) 1983-07-06 1984-06-27 7-(Pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments.
MX201827A MX156436A (en) 1983-07-06 1984-06-28 PROCEDURE TO PREPARE DERIVATIVES OF 7- (PIRROL-1-IL) OF ACIDS -1-ETIL-1, 4-DIHIDRO -4-OXOQUINOLEIN-3-CARBOXILICO AND 1-ETIL-1, 4-DIHDRO -4-OXO- (1,8-NAFTIRIDIN) -3-CARBOXYLIC SUBSTITUTED
EP84401391A EP0134165B1 (en) 1983-07-06 1984-06-29 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments
AT84401391T ATE34982T1 (en) 1983-07-06 1984-06-29 7-(PYRROL-1-YL)-1-ETHYL-1,4-DIHYDRO-4-OXOCHINOL N-3-CARBONIC ACID DERIVATIVES AND 7-(PYRROL-1-YL)-1ETHYL-1,4-DIHYDRO-4 -OXO-1,8-NAPHTYRIDIN-3CARBONS|URE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS.
DE8484401391T DE3471934D1 (en) 1983-07-06 1984-06-29 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments
RO115120A RO88915B (en) 1983-07-06 1984-07-03 Process for the preparation of 1-ethyl-1,4-dihydro-4-oxo--quinoline-3-carboxylic and 1-ethyl-1, 4-dihydro-4-oxo-1, 8-naphtiridin-3-carboxylic acid derivatives
PL1984248545A PL143730B1 (en) 1983-07-06 1984-07-03 Process for preparing derivatives of 7-/pyrrolyl-1-/-1-ethyl-1,4-dihydro-4-ketoquinoline-/or-4-keto-1,8-naphtiridine/-3-carboxylic acid
IN536/DEL/84A IN161611B (en) 1983-07-06 1984-07-03
GR75174A GR81646B (en) 1983-07-06 1984-07-03
JP59138851A JPS6036482A (en) 1983-07-06 1984-07-04 7-(1-pyrrolyl)-1-ethyl-1,4-dihydro-4-oxoquinoline- 3-carboxylic acid and 7-(1-pyrrolyl)-1-ethyl-1,4-dihydro -4-oxo-1,8-naphthylidine-3-carboxylic acid derivatives, manufacture and medicines
NO842717A NO163329C (en) 1983-07-06 1984-07-04 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DERIVATIVES OF 7- (PYRROL-1-YL) -1-ETHYL-1,4-DIHYDRO-4-OXO-QUINOLIN-3-CARBOXYLIC ACID AND 7- (PYRROL-1-YL) Ethyl 1,4-dihydro-4-oxo- (1,8-naphthyridine) -3-carboxylic acid.
SU843759901A SU1322980A3 (en) 1983-07-06 1984-07-05 Method of producing derivatives of 7-(pyrrole-1-yl)-1-ethyl-1,4-dihydro-4-oxo-quinolein-3-carboxylic and 7-(pyrrole-1-yl)-1-ethyl-1,4-dihydro-4-oxo-(1,8-naphthyridene)-3-carboxylic acids
PT78854A PT78854B (en) 1983-07-06 1984-07-05 PROCESS FOR PREPARING 7- (PYRROL-1-YL) DERIVATIVES OF 1-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXILIC ACIDS AND 1-ETHYL-1,4-DIHYDRO-4-OXO- (1) , 8-NAPHTHYRIDINE) -3-CARBOXILIC SUBSTITUTES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
BR8403342A BR8403342A (en) 1983-07-06 1984-07-05 DERIVATIVES FROM 7- (PIRROL-1-IL) -1-ETHYL-1,4-DI-HYDRO-4-OXO-QUINOLEIN-3-CARBONOXYLIC AND 7- (PIRROL-1-IL) -1-ETHYL-1 , 4-DI-HYDRO-4-OXO (1,8-NAFTIRIDIN) -3-CARBOXYLIC, PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS
DK331384A DK163126C (en) 1983-07-06 1984-07-05 1-ETHYL-1,4-DIHYDRO-4-OXO-3-CARBOXY-QUINOLINE OR (1,8-NAPHTHYRIDINE) DERIVATIVES, PROCEDURES FOR PREPARING THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THOSE INCLUDING THIS PART
HU842641A HU189916B (en) 1983-07-06 1984-07-05 Process for production of substituated-1-ethil-1,4-dihydro-4-oxo-kinolin-3-carboxylic acids and 7-/l-pirolil/-derivates of 1-ethil-1,4-dihydro-4-oxo-1,8-naftiridin-3-carboxylic acids and medical preparates consisting of such compounds
DD84264967A DD223150A5 (en) 1983-07-06 1984-07-05 PROCESS FOR PREPARING 7- (PYRROL-1-YL) DERIVATIVES OF SUBSTITUTED 1-ETHYL-1,4-DIHYDRO-4-OXOCHINOLINE-3-CARBOXYLSAEURE
CS845285A CS244139B2 (en) 1983-07-06 1984-07-06 Method of 7-(1-pyrrolyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxyl acid's and 7(1-pyrrolyl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridin-3-carboxyl acid's derivatives production
KR1019840003918A KR880002355B1 (en) 1983-07-06 1984-07-06 Method for preparing carboxylic acid derivative
YU1190/84A YU43577B (en) 1983-07-06 1984-07-06 Process for making derivatives of 7-(pyrol-1-il) 1-ethyl-1,4-dihydro-4-oxo-1,8-naphtyridine-3-carbonic acid
HK104/91A HK10491A (en) 1983-07-06 1991-02-06 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8311250A FR2548664B1 (en) 1983-07-06 1983-07-06 7- (PYRROL-L-YL) DERIVATIVES OF L-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXYLIC ACIDS AND L-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDINE) ) -3-SUBSTITUTED CARBOXYLICS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

Publications (2)

Publication Number Publication Date
FR2548664A1 FR2548664A1 (en) 1985-01-11
FR2548664B1 true FR2548664B1 (en) 1986-03-21

Family

ID=9290571

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8311250A Expired FR2548664B1 (en) 1983-07-06 1983-07-06 7- (PYRROL-L-YL) DERIVATIVES OF L-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXYLIC ACIDS AND L-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDINE) ) -3-SUBSTITUTED CARBOXYLICS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

Country Status (6)

Country Link
JP (1) JPS6036482A (en)
FR (1) FR2548664B1 (en)
IN (1) IN161611B (en)
RO (1) RO88915B (en)
SU (1) SU1322980A3 (en)
ZA (1) ZA844693B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1221492B (en) * 1984-03-13 1990-07-06 Biochem Design Srl ACIDS 7- (1-PIRRIL) -E 7- (1-PIRROLI-DINIL) -6-FLUORO-1-ETHYL-1,4-DIIDRO-4-KETOCHINOLIN-3-CARBOXYLS WITH ANTI-MICROBIAL ACTIVITIES, THEIR PREPARATION PROCEDURE AND PHARMACEUTICAL COMPOUNDS THAT CONTAIN THEM
US6080756A (en) * 1995-08-29 2000-06-27 Pfizer Inc. Polymorphs of the prodrug 6-N-(L-ALA-L-ALA)-trovafloxacin
DK0992501T3 (en) * 1995-09-22 2002-10-28 Wakunaga Pharma Co Ltd Pyridonecarboxylic acid derivatives as antibacterial agents
SK286420B6 (en) * 1997-09-15 2008-09-05 The Procter & Gamble Company Derivative of quinolone structure, pharmaceutical composition comprising the same and their use
AU3192700A (en) 1999-03-17 2000-10-04 Daiichi Pharmaceutical Co., Ltd. Medicinal compositions
MXPA02000103A (en) * 1999-07-01 2003-07-21 Wakunaga Pharma Co Ltd Quinolinecarboxylic acid derivative or salts thereof.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1006521A (en) * 1972-12-18 1977-03-08 Minoru Sugita Piperazine derivatives and process for preparing them
JPS5233694A (en) * 1975-09-09 1977-03-14 Dai Ichi Seiyaku Co Ltd Process for preparation of 6_nitro-1,8-naphthyridine derivatives
AR223983A1 (en) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co A PROCEDURE FOR PREPARING 6-HALOGEN-4-OXO-7- (1-PIPERAZINYL) -1,8-NAFTIRIDIN-3-CARBOXYLIC ACID DERIVATIVES

Also Published As

Publication number Publication date
RO88915B (en) 1987-07-01
ZA844693B (en) 1985-02-27
JPS6036482A (en) 1985-02-25
RO88915A (en) 1987-06-30
IN161611B (en) 1988-01-02
FR2548664A1 (en) 1985-01-11
SU1322980A3 (en) 1987-07-07
JPH026756B2 (en) 1990-02-13

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