FI864191A0 - Karboxiamidderivat och deras framstaellning. - Google Patents

Karboxiamidderivat och deras framstaellning.

Info

Publication number: FI864191A0
Authority: FI; Finland
Prior art keywords: carboxide; framstaellning; derivatives; carboxide derivatives
Prior art date: 1985-10-17

Application number

FI864191A

Other languages

English (en)

Other versions

FI864191A7 (fi

FI83866C (fi

FI83866B (fi

Inventor

Peter Robert Bernstein

Frederick Jeffrey Brown

Victor Giulio Matassa

Ying Kwong Yee

Original Assignee

Ici America Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-17

Filing date

1986-10-16

Publication date

1986-10-16

1985-10-17 Priority claimed from GB858525658A external-priority patent/GB8525658D0/en

1986-04-15 Priority claimed from GB868609176A external-priority patent/GB8609176D0/en

1986-10-16 Application filed by Ici America Inc filed Critical Ici America Inc

1986-10-16 Publication of FI864191A0 publication Critical patent/FI864191A0/fi

1987-04-18 Publication of FI864191A7 publication Critical patent/FI864191A7/fi

1991-05-31 Application granted granted Critical

1991-05-31 Publication of FI83866B publication Critical patent/FI83866B/fi

1991-09-10 Publication of FI83866C publication Critical patent/FI83866C/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI864191A 1985-10-17 1986-10-16 Foerfarande foer framstaellning av farmaceutiskt aktiva heterocykliska amider. FI83866C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB8525658		1985-10-17
GB858525658A GB8525658D0 (en)	1985-10-17	1985-10-17	Heterocyclic amide derivatives
GB8609176		1986-04-15
GB868609176A GB8609176D0 (en)	1986-04-15	1986-04-15	Carboxamide derivatives

Publications (4)

Publication Number	Publication Date
FI864191A0 true FI864191A0 (fi)	1986-10-16
FI864191A7 FI864191A7 (fi)	1987-04-18
FI83866B FI83866B (fi)	1991-05-31
FI83866C FI83866C (fi)	1991-09-10

Family

ID=26289900

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI864191A FI83866C (fi)	1985-10-17	1986-10-16	Foerfarande foer framstaellning av farmaceutiskt aktiva heterocykliska amider.

Country Status (19)

Country	Link
US (3)	US4918094A (fi)
EP (1)	EP0220066B1 (fi)
JP (1)	JP2512724B2 (fi)
KR (1)	KR900004385B1 (fi)
AU (1)	AU595839B2 (fi)
CA (1)	CA1336192C (fi)
DE (1)	DE3684549D1 (fi)
DK (1)	DK169964B1 (fi)
ES (1)	ES2032384T3 (fi)
FI (1)	FI83866C (fi)
GB (1)	GB8623429D0 (fi)
GR (1)	GR3004137T3 (fi)
HK (1)	HK18197A (fi)
HU (1)	HU197724B (fi)
IE (1)	IE60480B1 (fi)
IL (1)	IL80335A (fi)
NO (1)	NO170482C (fi)
NZ (1)	NZ217962A (fi)
PT (1)	PT83558B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT83559B (pt) *	1985-10-17	1989-05-31	Ici America Inc	Processo para a preparacao de novos derivados de indol e indazol-ceto-sulfona e de composicoes farmaceuticas que os contem
US5041460A (en) *	1988-04-14	1991-08-20	Ici Americas Inc.	Heter-aliphatic carboxamides
GB8927981D0 (en) *	1989-12-11	1990-02-14	Ici Plc	Carbamoyl derivative
US5286740A (en) *	1989-12-11	1994-02-15	Imperial Chemical Industries Plc	Carbamoyl derivatives
ES2063479T3 (es) *	1990-05-04	1995-01-01	Ciba Geigy Ag	Indoles substituidos.
US5095031A (en) *	1990-08-20	1992-03-10	Abbott Laboratories	Indole derivatives which inhibit leukotriene biosynthesis
GB9026427D0 (en) *	1990-12-05	1991-01-23	Ici Plc	Chemical process
EP0511477B1 (en) *	1991-03-11	1996-07-10	Kyowa Hakko Kogyo Co., Ltd.	Indole derivatives
GB9119001D0 (en) *	1991-09-05	1991-10-23	Ici Plc	Pharmaceutical agents
ES2072125T3 (es) *	1991-10-25	1995-07-01	Ciba Geigy Ag	Procedimiento para la obtencion de indoles substituidos.
EP0539329A1 (de) *	1991-10-25	1993-04-28	Ciba-Geigy Ag	Acetylen-Verbindungen, verwendbar als Leukotrien-Antagonisten
ES2050611B1 (es) *	1992-10-08	1994-12-16	Ici Plc	Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos.
US5288743A (en) *	1992-11-20	1994-02-22	Abbott Laboratories	Indole carboxylate derivatives which inhibit leukotriene biosynthesis
WO2001007031A1 (en) *	1999-07-26	2001-02-01	Shionogi & Co., Ltd.	Benzene derivatives and immunopotentiating compositions or drug-sensitivity restoring agents containing the same
US6614627B1 (en) *	2000-02-14	2003-09-02	Hitachi, Ltd.	Magnetic disk apparatus
US8569512B2 (en) *	2009-03-23	2013-10-29	Merck Sharp & Dohme Corp.	P2X3 receptor antagonists for treatment of pain
JP2020111510A (ja) *	2017-03-29	2020-07-27	科研製薬株式会社	インダゾール誘導体及びそれを含有する医薬

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3271416A (en) *	1961-10-24	1966-09-06	Merck & Co Inc	Indolyl aliphatic acids
FR4035M (fi) *	1964-11-04	1966-03-28
FR7631M (fi) *	1968-08-13	1970-01-26
US3470298A (en) *	1969-01-29	1969-09-30	Acraf	Topical anti-inflammatory composition containing (indazole-3-yl)-oxyalkanoic acids
BE738727A (en) *	1969-09-11	1970-02-16		Anti inflammatory analgesic and antipyretic indolyalkanoic - acids and derivs
DE2854987A1 (de) *	1978-12-20	1980-06-26	Boehringer Mannheim Gmbh	Diagnostische mittel zum nachweis proteolytischer enzyme und dafuer geeignete chromogene
IE54269B1 (en) *	1981-12-30	1989-08-02	Ici America Inc	Pharmaceutically active phenylcarboxylic acid derivatives
CA1241660A (en) *	1984-06-25	1988-09-06	Yvan Guindon	Indole-2-alkanoic acids
GB8426474D0 (en) *	1984-10-19	1984-11-28	Ici America Inc	Heterocyclic amides
GB8524157D0 (en) *	1984-10-19	1985-11-06	Ici America Inc	Heterocyclic amides
GB8607294D0 (en) *	1985-04-17	1986-04-30	Ici America Inc	Heterocyclic amide derivatives

1986
- 1986-09-30 GB GB868623429A patent/GB8623429D0/en active Pending
- 1986-10-16 IE IE273886A patent/IE60480B1/en not_active IP Right Cessation
- 1986-10-16 HU HU864302A patent/HU197724B/hu not_active IP Right Cessation
- 1986-10-16 DE DE8686308054T patent/DE3684549D1/de not_active Expired - Lifetime
- 1986-10-16 NO NO864130A patent/NO170482C/no not_active IP Right Cessation
- 1986-10-16 PT PT83558A patent/PT83558B/pt not_active IP Right Cessation
- 1986-10-16 AU AU63985/86A patent/AU595839B2/en not_active Ceased
- 1986-10-16 NZ NZ217962A patent/NZ217962A/xx unknown
- 1986-10-16 US US06/919,845 patent/US4918094A/en not_active Expired - Lifetime
- 1986-10-16 KR KR1019860008670A patent/KR900004385B1/ko not_active Expired
- 1986-10-16 IL IL80335A patent/IL80335A/xx not_active IP Right Cessation
- 1986-10-16 JP JP61246448A patent/JP2512724B2/ja not_active Expired - Lifetime
- 1986-10-16 DK DK495886A patent/DK169964B1/da not_active IP Right Cessation
- 1986-10-16 ES ES198686308054T patent/ES2032384T3/es not_active Expired - Lifetime
- 1986-10-16 EP EP86308054A patent/EP0220066B1/en not_active Expired - Lifetime
- 1986-10-16 FI FI864191A patent/FI83866C/fi not_active IP Right Cessation
- 1986-10-17 CA CA000520794A patent/CA1336192C/en not_active Expired - Fee Related
1989
- 1989-12-29 US US07/458,868 patent/US5049679A/en not_active Expired - Lifetime
- 1989-12-29 US US07/458,876 patent/US5049576A/en not_active Expired - Lifetime
1992
- 1992-03-26 GR GR910401149T patent/GR3004137T3/el unknown
1997
- 1997-02-13 HK HK18197A patent/HK18197A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR870003983A (ko)	1987-05-06
NZ217962A (en)	1990-03-27
EP0220066A3 (en)	1988-10-12
IL80335A (en)	1990-02-09
EP0220066A2 (en)	1987-04-29
NO170482C (no)	1992-10-21
AU595839B2 (en)	1990-04-12
GR3004137T3 (fi)	1993-03-31
FI864191A7 (fi)	1987-04-18
HK18197A (en)	1997-02-13
DK169964B1 (da)	1995-04-18
US5049679A (en)	1991-09-17
PT83558B (pt)	1989-05-31
FI83866C (fi)	1991-09-10
KR900004385B1 (ko)	1990-06-23
DK495886D0 (da)	1986-10-16
HU197724B (en)	1989-05-29
EP0220066B1 (en)	1992-03-25
NO864130D0 (no)	1986-10-16
IE862738L (en)	1987-04-17
CA1336192C (en)	1995-07-04
NO864130L (no)	1987-04-21
DE3684549D1 (de)	1992-04-30
AU6398586A (en)	1987-04-30
NO170482B (no)	1992-07-13
JPS6299359A (ja)	1987-05-08
PT83558A (en)	1986-11-01
ES2032384T3 (es)	1993-02-16
US4918094A (en)	1990-04-17
DK495886A (da)	1987-04-18
JP2512724B2 (ja)	1996-07-03
IE60480B1 (en)	1994-07-13
GB8623429D0 (en)	1986-11-05
FI83866B (fi)	1991-05-31
HUT42441A (en)	1987-07-28
US5049576A (en)	1991-09-17

Legal Events

Date	Code	Title	Description
1994-06-17	TC	Name/ company changed in patent	Owner name: ZENECA INC.
2004-08-31	MM	Patent lapsed	Owner name: ZENECA INC.

Publication	Publication Date	Title
FI863919L (fi)	1987-03-31	Packningsfilm av termoplast med maonga skikt och paosar gjorda daerav.
FI861340L (fi)	1986-09-30	Engaongsbloejor med enhetligt midjeskydd och elastiskt taenjbara midjeband.
FI862952A0 (fi)	1986-07-15	Foerfarande foer styrning av slagkolvens roerelse i en slagborrmaskin fungerande med en icke- kompressibel tryckvaetska och anordning foer utfoerande av detta foerfarande.
FI883229A7 (fi)	1988-07-06	Foerfarande foer reducering av kolvhastigheten i speciellt en arbetsmaskin kolv- och cylinderaggregat och anordning foer utfoerande av foerfarandet.
FI864519L (fi)	1987-05-08	En reaktor foersedd med en foerdelningsanordning foer cirkulationsvaetska och anvaendning av densamma.
FI864231L (fi)	1987-04-22	Fytoaktiva kompositioner i vaetskeform och foerfarande foer deras framstaellning.
FI863433A7 (fi)	1987-05-26	Foerfarande och anordning foer maetning av ytnivaon i reaktortryckbehaollaren i en kokvattenreaktor.
FI861074A0 (fi)	1986-03-14	Citrusfruktkoncentrat och laeskedryck med foerbaettrad lagringsbestaendighet.
FI872638A0 (fi)	1987-06-12	Foerbaettring i och avseende brustabletter av acetylsalisylsyra.
FI864191A0 (fi)	1986-10-16	Karboxiamidderivat och deras framstaellning.
FI892219L (fi)	1989-05-09	Foerfarande och komposition foer effektivering av foerbraenningen i foerbraenningsprocesser innehaollande kolvaetefoereningar.
FI861957A0 (fi)	1986-05-09	Foerfarande och anordning foer detektering av spaerrtillstaondet i en slaeckbar tyristor.
FI860374A7 (fi)	1986-07-29	Tvaettmedelskomposition foer textiler med mjukgoerande och antistatisk effekt.
FI861079L (fi)	1986-09-16	Dynamisk frekvensdelare med blandare och foerstaerkare.
FI80868B (fi)	1990-04-30	Anordning foer montering och demontering av en rulle i en lindningsapparat.
FI860979L (fi)	1986-09-13	Foerfarande och profilfog.
DE3680771D1 (de)	1991-09-12	Isoxazolopyridophenoxazin- und isothiazolopyridophenoxazinderivate.
FI854671A0 (fi)	1985-11-26	Foerfarande och anordning foer foerbaettrande av malresultatet i en tryckammarkvarn.
FI882678A0 (fi)	1988-06-07	Foerfarande och anordning i presspartiet i en pappersmaskin.
DE3680775D1 (de)	1991-09-12	Isoxazolopyridobenzoxazin- und isothiazolopyridobenzoxazinderivate.
FI861533A0 (fi)	1986-04-10	Vaetskeackumulator och hydrauliskt slagverk med en saodan.
FI852395A0 (fi)	1985-06-17	Foerfarande foer tillvaratagande och tillgodogoerande av svaveldioxiden i svavelhaltiga gaser saosom roekgaser.
FI852145A0 (fi)	1985-05-29	Saett foer matning av traed i barktrumma och anordning foer barkning av traed.
FI854658L (fi)	1987-05-27	Foerfarande och anordning foer tillslutning av mynningen i en storsaeck.
FI850638A0 (fi)	1985-02-15	Foerfarande och anordning i inloppslaodan av en pappersmaskin foer styrning av snedvridningen i pappersbanans fiberorientering.