EP1048673A4 - Neovascularization inhibitor containing dienogest as the active ingredient - Google Patents

Neovascularization inhibitor containing dienogest as the active ingredient

Info

Publication number
EP1048673A4
EP1048673A4 EP19980961588 EP98961588A EP1048673A4 EP 1048673 A4 EP1048673 A4 EP 1048673A4 EP 19980961588 EP19980961588 EP 19980961588 EP 98961588 A EP98961588 A EP 98961588A EP 1048673 A4 EP1048673 A4 EP 1048673A4
Authority
EP
European Patent Office
Prior art keywords
active ingredient
inhibitor containing
neovascularization inhibitor
containing dienogest
dienogest
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19980961588
Other languages
German (de)
French (fr)
Other versions
EP1048673A1 (en
Inventor
Yoshihiro Futamura
Masaki Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Publication of EP1048673A1 publication Critical patent/EP1048673A1/en
Publication of EP1048673A4 publication Critical patent/EP1048673A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP19980961588 1997-12-26 1998-12-25 Neovascularization inhibitor containing dienogest as the active ingredient Withdrawn EP1048673A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP36954097 1997-12-26
JP36954097 1997-12-26
PCT/JP1998/005944 WO1999033856A1 (en) 1997-12-26 1998-12-25 Neovascularization inhibitor containing dienogest as the active ingredient

Publications (2)

Publication Number Publication Date
EP1048673A1 EP1048673A1 (en) 2000-11-02
EP1048673A4 true EP1048673A4 (en) 2002-10-25

Family

ID=18494688

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980961588 Withdrawn EP1048673A4 (en) 1997-12-26 1998-12-25 Neovascularization inhibitor containing dienogest as the active ingredient

Country Status (6)

Country Link
US (1) US6569845B1 (en)
EP (1) EP1048673A4 (en)
JP (1) JP4418105B2 (en)
AU (1) AU1690399A (en)
CA (1) CA2316303A1 (en)
WO (1) WO1999033856A1 (en)

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* Cited by examiner, † Cited by third party
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EP2438913B1 (en) * 2002-03-20 2020-05-06 University of Maryland, Baltimore A non-selective cation channel in neural cells and compounds that block the channel for use in treating brain swelling
US8980952B2 (en) * 2002-03-20 2015-03-17 University Of Maryland, Baltimore Methods for treating brain swelling with a compound that blocks a non-selective cation channel
JP2005104862A (en) * 2003-09-29 2005-04-21 Meiji Milk Prod Co Ltd Age-related macular degeneration treatment
CN101072797B (en) 2004-03-12 2012-05-09 瓦斯基因治疗公司 Antibodies that bind EPHB4, inhibit angiogenesis and tumor growth
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
EP1802313B1 (en) * 2004-09-18 2010-11-03 University of Maryland, Baltimore Therapeutic agents trageting the ncca-atp channel and methods of use thereof
JP5085326B2 (en) * 2004-09-18 2012-11-28 ユニバーシティ オブ メリーランド，ボルチモア Treatment agent targeting NCCa-ATP channel and method of use thereof
CA2581423A1 (en) 2004-09-23 2006-03-30 Vasgene Therapeutics, Inc. Polipeptide compounds for inhibiting angiogenesis and tumor growth
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP1934867A2 (en) * 2005-08-31 2008-06-25 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
SG10201400426XA (en) 2006-01-12 2014-07-30 Alexion Pharma Inc Antibodies to ox-2/cd200 and uses thereof
US20090298093A1 (en) * 2006-04-27 2009-12-03 Roberto Polakiewicz Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways
US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
CN101153054B (en) * 2006-09-30 2012-02-22 北京市肿瘤防治研究所 Small peptides for angiogenesis therapy and applications thereof
US9511075B2 (en) * 2007-01-12 2016-12-06 The University Of Maryland, Baltimore Targeting NCCA-ATP channel for organ protection following ischemic episode
MX2009008222A (en) 2007-02-01 2009-10-12 Acceleron Pharma Inc Activin-actriia antagonists and uses for treating or preventing breast cancer.
EP2114160B1 (en) * 2007-02-09 2016-11-16 University of Maryland, Baltimore Antagonists of a non-selective cation channel in neural cells
US20080214512A1 (en) * 2007-03-01 2008-09-04 Christian Seitz Pharmaceutical preparation containing a gestagen, and kit and method for treating endometriosis using the preparation
US20090081659A1 (en) 2007-03-07 2009-03-26 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20090068684A1 (en) * 2007-03-26 2009-03-12 Cell Signaling Technology, Inc. Serine and threoninephosphorylation sites
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
EP2145902A3 (en) 2007-04-19 2010-09-29 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
EP1983003A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
US20090053831A1 (en) 2007-05-01 2009-02-26 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
CA2691199C (en) 2007-06-22 2017-09-12 Marc J. Simard Inhibitors of ncca-atp channels for therapy
EP2027855A1 (en) 2007-08-24 2009-02-25 Bayer Schering Pharma AG Use of gestagens in combination with (6S)5-methyl tetrahydro folate for endometriosis therapy with simultaneous reduction of the side effects of therapy and reduction in the risk of congenital deformities for with the onset of pregnancy
US20090060997A1 (en) * 2007-08-27 2009-03-05 Christian Seitz Process for producing a pharmaceutical preparation for therapeutic treatment of endometriosis containing a combination of a gestagen and (6s)-5-methyltetrahydrofolate
CN101861161B (en) 2007-09-18 2017-04-19 阿塞勒隆制药公司 ACTIN-ACTRIIA ANTAGONISTS AND USE FOR REDUCING OR INHIBITING FSH SECRETION
US20090203043A1 (en) 2007-11-21 2009-08-13 Peter Hornbeck Protein phosphorylation by basophilic serine/threonine kinases in insulin signaling pathways
US20090220991A1 (en) * 2008-02-29 2009-09-03 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
WO2013116096A1 (en) 2012-01-31 2013-08-08 Purdue Research Foundation Methods for determining aggressiveness of a cancer and treatment thereof
CA2868883C (en) 2012-03-30 2022-10-04 Sorrento Therapeutics Inc. Fully human antibodies that bind to vegfr2
EP4026849A1 (en) 2016-09-26 2022-07-13 Ensemble Group Holdings Methods of assessing and treating cancer in subjects having dysregulated lymphatic systems using a combination of vegfr-3 and pd-1 or pd-l1 inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0654267A1 (en) * 1993-11-19 1995-05-24 Mochida Pharmaceutical Co., Ltd. Carcinostatic for hormonotheraphy containing dienogest as effective component
JPH07188026A (en) * 1993-11-19 1995-07-25 Mochida Pharmaceut Co Ltd Anticancer drug for hormone therapy containing dienogest as an active ingredient

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS539216B2 (en) * 1973-11-28 1978-04-04
JPS57116698A (en) * 1981-01-12 1982-07-20 Zebra Co Ltd Knock type propelling pencil
DE4321957C2 (en) * 1993-07-01 1995-09-28 Marika Dr Med Ehrlich Use of a hormonal agent to treat acne
DK0754701T3 (en) 1994-04-04 1999-05-17 Meiji Milk Prod Co Ltd Hitherto unknown progesterone compound and its use
US5994388A (en) * 1997-03-18 1999-11-30 The Children's Medical Center Corporation Cytochalasin and isoindolinone derivatives as inhibitors of angiogenesis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0654267A1 (en) * 1993-11-19 1995-05-24 Mochida Pharmaceutical Co., Ltd. Carcinostatic for hormonotheraphy containing dienogest as effective component
JPH07188026A (en) * 1993-11-19 1995-07-25 Mochida Pharmaceut Co Ltd Anticancer drug for hormone therapy containing dienogest as an active ingredient

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN *
See also references of WO9933856A1 *

Also Published As

Publication number Publication date
AU1690399A (en) 1999-07-19
JP4418105B2 (en) 2010-02-17
EP1048673A1 (en) 2000-11-02
WO1999033856A1 (en) 1999-07-08
US6569845B1 (en) 2003-05-27
CA2316303A1 (en) 1999-07-08

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