DK272684A - Tetrahydro-beta-carbolin-derivater og fremgangsmaade til fremstilling deraf - Google Patents

Tetrahydro-beta-carbolin-derivater og fremgangsmaade til fremstilling deraf Download PDF

Info

Publication number: DK272684A
Authority: DK; Denmark
Prior art keywords: tetrahydro; group; procedures; preparing; alkyl group
Prior art date: 1983-06-04

Application number

DK272684A

Other languages

English (en)

Other versions

DK272684D0 (da

Inventor

Ikuo Iijima

Yutaka Saiga

Toshikazu Miyagishima

Yuzo Matsuoka

Mamoru Matsumoto

Original Assignee

Tanabe Seiyaku Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-04

Filing date

1984-06-01

Publication date

1984-12-05

1984-06-01 Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co

1984-06-01 Publication of DK272684D0 publication Critical patent/DK272684D0/da

1984-12-05 Publication of DK272684A publication Critical patent/DK272684A/da

Links

CFTOTSJVQRFXOF-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole Chemical class N1C2=CC=CC=C2C2=C1CNCC2 CFTOTSJVQRFXOF-UHFFFAOYSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
206010067125 Liver injury Diseases 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
231100000234 hepatic damage Toxicity 0.000 abstract 1
230000008818 liver damage Effects 0.000 abstract 1
208000019423 liver disease Diseases 0.000 abstract 1
230000000069 prophylactic effect Effects 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
- C08G67/02—Copolymers of carbon monoxide and aliphatic unsaturated compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Polymers & Plastics (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK272684A 1983-06-04 1984-06-01 Tetrahydro-beta-carbolin-derivater og fremgangsmaade til fremstilling deraf DK272684A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB08315403A GB2140797A (en)	1983-06-04	1983-06-04	Tetrahydro-b-carboline derivatives

Publications (2)

Publication Number	Publication Date
DK272684D0 DK272684D0 (da)	1984-06-01
DK272684A true DK272684A (da)	1984-12-05

Family

ID=10543822

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK272684A DK272684A (da)	1983-06-04	1984-06-01	Tetrahydro-beta-carbolin-derivater og fremgangsmaade til fremstilling deraf

Country Status (13)

Country	Link
US (1)	US4612317A (da)
EP (1)	EP0128021B1 (da)
JP (1)	JPS59225187A (da)
KR (1)	KR870001239B1 (da)
AT (1)	ATE29496T1 (da)
AU (1)	AU563923B2 (da)
CA (1)	CA1251449A (da)
DE (1)	DE3465995D1 (da)
DK (1)	DK272684A (da)
ES (1)	ES8702909A1 (da)
GB (1)	GB2140797A (da)
HU (1)	HU198928B (da)
SU (1)	SU1382401A3 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040253891A1 (en) *	2000-09-12	2004-12-16	Schierenbeck Alan W.	Composite structure for protective garment
US20050137220A1 (en) *	2003-07-23	2005-06-23	Pharmacia Corporation	Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors
FR2869540B1 (fr) *	2004-04-30	2008-05-16	Centre Nat Rech Scient Cnrse	Compositions pharmaceutiques contenant des derives de b-carboline, et leur utilisation pour le traitement des cancers
JP5649170B2 (ja) *	2010-11-26	2015-01-07	国立大学法人千葉大学	テトラヒドロ−β−カルボリン誘導体及びその製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA668301A (en) *		1963-08-06	Leonard Frederick	PROCESS FOR THE PREPARATION OF NEW .beta.-CARBOLINE DERIVATIVES
DE20923C (de) *			H. LAMPRECHT In Gnarrenburg und G. HlRDES in Bremen	Neuerungen an Tropfenzählern
DD20923A (da) *
US2187719A (en) *	1938-06-10	1940-01-23	Du Pont	Derivative of hexamethylene-di-thio-carbamic acid
ES273769A1 (es) *	1961-01-18	1962-06-01	Geigy Ag J R	Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico
JPS5826755B2 (ja) *	1975-09-01	1983-06-04	オオキサダオ	３− ヒドロキシメチル − ベ−タ − カルボリンユウドウタイノセイゾウホウ

1983
- 1983-06-04 GB GB08315403A patent/GB2140797A/en not_active Withdrawn
1984
- 1984-05-18 US US06/611,965 patent/US4612317A/en not_active Expired - Fee Related
- 1984-05-28 JP JP59109300A patent/JPS59225187A/ja active Pending
- 1984-05-29 KR KR1019840002970A patent/KR870001239B1/ko not_active Expired
- 1984-05-31 CA CA000455559A patent/CA1251449A/en not_active Expired
- 1984-05-31 AU AU28874/84A patent/AU563923B2/en not_active Ceased
- 1984-06-01 AT AT84303685T patent/ATE29496T1/de not_active IP Right Cessation
- 1984-06-01 SU SU843749299A patent/SU1382401A3/ru active
- 1984-06-01 ES ES533080A patent/ES8702909A1/es not_active Expired
- 1984-06-01 DK DK272684A patent/DK272684A/da not_active Application Discontinuation
- 1984-06-01 EP EP84303685A patent/EP0128021B1/en not_active Expired
- 1984-06-01 DE DE8484303685T patent/DE3465995D1/de not_active Expired
- 1984-06-04 HU HU842165A patent/HU198928B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU563923B2 (en)	1987-07-30
KR850000034A (ko)	1985-02-25
HU198928B (en)	1989-12-28
EP0128021B1 (en)	1987-09-09
ES8702909A1 (es)	1987-01-16
DK272684D0 (da)	1984-06-01
CA1251449A (en)	1989-03-21
ES533080A0 (es)	1987-01-16
HUT34191A (en)	1985-02-28
DE3465995D1 (en)	1987-10-15
KR870001239B1 (ko)	1987-06-26
GB2140797A (en)	1984-12-05
ATE29496T1 (de)	1987-09-15
JPS59225187A (ja)	1984-12-18
SU1382401A3 (ru)	1988-03-15
US4612317A (en)	1986-09-16
AU2887484A (en)	1984-12-06
GB8315403D0 (en)	1983-07-06
EP0128021A1 (en)	1984-12-12

Legal Events

Date	Code	Title	Description
1992-02-24	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
ES527954A1 (es)	1985-11-01	Un procedimiento para preparar isoxazoles
SE8104456L (sv)	1982-01-22	Hydantoinderivat, sett for framstellning derav och lekemedel innehallande dem
NO823836L (no)	1983-05-18	Fremgangsmaate ved fremstilling av antifibrinolytisk aktive forbindelser.
DK281482A (da)	1982-12-25	Fremgangsmaade til fremstilling af 2-aryl-3,4-diazabicyclo(4.n.o)alken-(2)-on-5-forbindelser
NO840037L (no)	1984-01-05	Cykloalifatiske farmasoeytiske forbindelser
DK400781A (da)	1982-03-11	Fremgangsmaade til fremstilling af 2-(1,4-benzodioxan-2-ylalkyl) imidazoler
DK272684A (da)	1984-12-05	Tetrahydro-beta-carbolin-derivater og fremgangsmaade til fremstilling deraf
SE8204418D0 (sv)	1982-07-21	N-imidazolyl-derivat av 1,2,3,4-tetrahydronaftalen, indan och 2-substituerad-1-kroman, och forfarande for deras framstellning
ES467948A1 (es)	1978-11-01	Un procedimiento para la preparacion de un derivado de fe- nilpiperazina.
ES516158A0 (es)	1983-07-01	Procedimiento de preparacion de nuevos derivados del adamantano.
NO890158D0 (no)	1989-01-13	Fremgangsmaate for fremstilling av hydroksialkyleringsmiddel, de oppnaadde midler og deres anvendelse.
DK82583D0 (da)	1983-02-23	Furyloxazolyleddikesyrederivater og fremgangsmader til fremstilling deraf
SE8207294D0 (sv)	1982-12-21	1,4-tiazankarboxylsyraderivat, deras framstellning och anvendning och kompositioner vari dessa derivat ingar
JPS5225765A (en)	1977-02-25	Preparation of novel isoindoline derivatives
ES509194A0 (es)	1983-01-16	Procedimiento para la preparacion de una nueva tiovinil-3 cefalosporina.
DE3168178D1 (en)	1985-02-21	2-(n-aryl-n-1,2,3-thiadiazolyl-carbonyl)-aminobutyrolactones, their preparation, fungicides containing them and their use as fungicides
GR851995B (da)	1985-12-17
DK263787A (da)	1987-11-24	Praeparat til anvendelse ved profylakse mod og helbredelse af arteriesclerose
JPS525743A (en)	1977-01-17	Process for preparation of 3-oxo-5-substituted -cyclohexene-1-ylmalona tes