DK237978A - Fremgangsmaade til fremstilling af alfafluormethyl-alfa-aminoalkansyrer - Google Patents

Fremgangsmaade til fremstilling af alfafluormethyl-alfa-aminoalkansyrer

Info

Publication number: DK237978A
Authority: DK; Denmark
Prior art keywords: cancids; alfafluoromethyl; aminoal; alfa; procedure
Prior art date: 1977-06-01

Application number

DK237978A

Other languages

English (en)

Other versions

DK149841B (da

DK149841C (da

Inventor

J Kollonitsch

A A Patchett

S Marburg

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-06-01

Filing date

1978-05-30

Publication date

1979-01-19

1977-06-01 Priority claimed from US05/802,391 external-priority patent/US4325961A/en

1978-05-30 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1979-01-19 Publication of DK237978A publication Critical patent/DK237978A/da

1986-10-13 Publication of DK149841B publication Critical patent/DK149841B/da

1987-04-21 Application granted granted Critical

1987-04-21 Publication of DK149841C publication Critical patent/DK149841C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

DK237978A 1977-06-01 1978-05-30 Analogifremgangsmaade til fremstilling af alfa-fluor-methyl-alfa-aminoalkansyrer eller farmaceutisk acceptable syreadditionssalte deraf DK149841C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US80238977A	1977-06-01	1977-06-01
US80239177		1977-06-01
US05/802,391 US4325961A (en)	1977-06-01	1977-06-01	Fluorinated amino acids
US80238977		1977-06-01

Publications (3)

Publication Number	Publication Date
DK237978A true DK237978A (da)	1979-01-19
DK149841B DK149841B (da)	1986-10-13
DK149841C DK149841C (da)	1987-04-21

Family

ID=27122442

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK237978A DK149841C (da)	1977-06-01	1978-05-30	Analogifremgangsmaade til fremstilling af alfa-fluor-methyl-alfa-aminoalkansyrer eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (26)

Country	Link
JP (1)	JPS5416423A (da)
AR (1)	AR223463A1 (da)
AT (1)	AT360509B (da)
AU (1)	AU518479B2 (da)
CA (1)	CA1120040A (da)
CH (1)	CH639639A5 (da)
DD (1)	DD138651A5 (da)
DE (1)	DE2824116A1 (da)
DK (1)	DK149841C (da)
ES (1)	ES470296A1 (da)
FI (1)	FI66840C (da)
FR (1)	FR2392958A1 (da)
GB (1)	GB1602525A (da)
GR (1)	GR64495B (da)
HK (1)	HK18184A (da)
HU (1)	HU181911B (da)
IE (1)	IE46983B1 (da)
IT (1)	IT1104709B (da)
LU (1)	LU79750A1 (da)
NL (1)	NL190485C (da)
NO (1)	NO147382C (da)
NZ (1)	NZ187377A (da)
PL (1)	PL115731B1 (da)
PT (1)	PT68102B (da)
SE (1)	SE7806440L (da)
YU (1)	YU129178A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL59481A0 (en) *	1977-07-11	1980-05-30	Merrell Toraude & Co	-halomethyl amino acids
CA1091661A (en) *	1977-07-11	1980-12-16	Philippe Bey	.alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
ZA783273B (en) *	1977-07-11	1979-06-27	Merrell Toraude & Co	A-halomethyl amino acids
US4315095A (en) *	1977-07-28	1982-02-09	Merrell Toraude Et Compagnie	α-Halomethyl derivatives of amino acids
DE2965364D1 (en) *	1978-07-24	1983-06-16	Merck & Co Inc	Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
IE49522B1 (en) *	1979-04-26	1985-10-16	Merrell Toraude & Co	Alpha-halomethylaminoacids
CA1158657A (en) *	1979-07-26	1983-12-13	Philippe Bey	Preparation of fluorinated methyl aminoalkanoic acids and novel process intermediates
ZA813018B (en) *	1980-05-09	1982-05-26	Merrell Toraude & Co	Fluoromethylated tyrosine methyl ester
SE460517B (sv) *	1980-06-16	1989-10-23	Merrell Pharma Inc	Anvaendning av en foerening foer framstaellning av ett laekemedel foer behandling av infektioner orsakade av trypanosoma brucei
US4421767A (en) *	1981-06-01	1983-12-20	Merrell Toraude Et Compagnie	Compounds and methods for treating depression
GB9325368D0 (en) *	1993-12-10	1994-02-16	Univ Bristol	Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3046300A (en) *	1960-10-21	1962-07-24	Merck & Co Inc	alpha-trifluoromethyloxyphenylalanines

1978
- 1978-05-25 GR GR56328A patent/GR64495B/el unknown
- 1978-05-25 NZ NZ187377A patent/NZ187377A/xx unknown
- 1978-05-25 FR FR7815567A patent/FR2392958A1/fr active Granted
- 1978-05-26 FI FI781674A patent/FI66840C/fi not_active IP Right Cessation
- 1978-05-26 AR AR272336A patent/AR223463A1/es active
- 1978-05-29 AU AU36586/78A patent/AU518479B2/en not_active Expired
- 1978-05-29 CA CA000304318A patent/CA1120040A/en not_active Expired
- 1978-05-29 ES ES470296A patent/ES470296A1/es not_active Expired
- 1978-05-30 IE IE1078/78A patent/IE46983B1/en unknown
- 1978-05-30 YU YU01291/78A patent/YU129178A/xx unknown
- 1978-05-30 GB GB24330/78A patent/GB1602525A/en not_active Expired
- 1978-05-30 DK DK237978A patent/DK149841C/da not_active IP Right Cessation
- 1978-05-30 PT PT68102A patent/PT68102B/pt unknown
- 1978-05-30 HU HU78ME2169A patent/HU181911B/hu unknown
- 1978-05-30 AT AT393278A patent/AT360509B/de not_active IP Right Cessation
- 1978-05-30 DD DD78205669A patent/DD138651A5/xx unknown
- 1978-05-31 PL PL1978207242A patent/PL115731B1/pl unknown
- 1978-05-31 CH CH597978A patent/CH639639A5/de not_active IP Right Cessation
- 1978-05-31 IT IT49637/78A patent/IT1104709B/it active
- 1978-05-31 NO NO781892A patent/NO147382C/no unknown
- 1978-06-01 JP JP6501678A patent/JPS5416423A/ja active Granted
- 1978-06-01 LU LU79750A patent/LU79750A1/xx unknown
- 1978-06-01 SE SE7806440A patent/SE7806440L/xx unknown
- 1978-06-01 DE DE19782824116 patent/DE2824116A1/de active Granted
- 1978-06-01 NL NLAANVRAGE7805981,A patent/NL190485C/xx not_active IP Right Cessation
1984
- 1984-03-01 HK HK181/84A patent/HK18184A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ187377A (en)	1981-05-15
YU129178A (en)	1983-01-21
HK18184A (en)	1984-03-09
IT1104709B (it)	1985-10-28
NO147382B (no)	1982-12-20
PT68102B (en)	1982-06-08
CH639639A5 (en)	1983-11-30
FI781674A7 (fi)	1978-12-02
DK149841B (da)	1986-10-13
DE2824116A1 (de)	1978-12-14
IE46983B1 (en)	1983-11-16
GB1602525A (en)	1981-11-11
FR2392958A1 (fr)	1978-12-29
HU181911B (en)	1983-11-28
GR64495B (en)	1980-03-31
NO147382C (no)	1983-03-30
AT360509B (de)	1981-01-12
ATA393278A (de)	1980-06-15
AU518479B2 (en)	1981-10-01
NL190485C (nl)	1994-03-16
FR2392958B1 (da)	1980-10-24
ES470296A1 (es)	1979-09-16
JPS5416423A (en)	1979-02-07
NL190485B (nl)	1993-10-18
IE781078L (en)	1978-12-01
PT68102A (en)	1978-06-01
AU3658678A (en)	1979-12-06
JPS641474B2 (da)	1989-01-11
DE2824116C2 (da)	1989-04-27
CA1120040A (en)	1982-03-16
FI66840C (fi)	1984-12-10
SE7806440L (sv)	1978-12-02
DK149841C (da)	1987-04-21
PL207242A1 (pl)	1979-04-23
PL115731B1 (en)	1981-04-30
DD138651A5 (de)	1979-11-14
FI66840B (fi)	1984-08-31
LU79750A1 (fr)	1979-02-02
NO781892L (no)	1978-12-04
NL7805981A (nl)	1978-12-05
IT7849637A0 (it)	1978-05-31
AR223463A1 (es)	1981-08-31

Legal Events

Date	Code	Title	Description
1988-02-01	PBP	Patent lapsed

Publication	Publication Date	Title
DK63178A (da)	1978-08-12	Fremgangsmaade til fremstilling af pyrrodinderivater
DK536178A (da)	1979-06-23	Fremgangsmaade til fremstilling af stilbenderivater
DK110778A (da)	1978-09-15	Fremgangsmaade til fremstilling af 4-acylamino-phenyl-ethanolaminer
DK306978A (da)	1979-01-12	Fremgangsmaade til fremstilling af 1-acyl-2-cyanaziridiner
DK484677A (da)	1979-04-04	Fremgangsmaade til fremstilling af furokumariner
DK569678A (da)	1979-06-21	Fremgangsmaade til fremstilling af 2alfa-cyano-3-oxosteroider
DK145701C (da)	1983-07-18	Fremgangsmaade til fremstilling af ergotalkaloider
DK466878A (da)	1979-04-21	Fremgangsmaade til fremstilling af 0-methallyloxyphenol
DK398078A (da)	1979-03-09	Fremgangsmaade til fremstilling af sulfonylamidinforbindelser
DK30578A (da)	1978-07-23	Fremgangsmaade til fremstilling af aminoalkoxyphenylderivater
DK237978A (da)	1979-01-19	Fremgangsmaade til fremstilling af alfafluormethyl-alfa-aminoalkansyrer
DK154949C (da)	1989-05-29	Fremgangsmaade til fremstilling af trifluormethylphenoler
DK436978A (da)	1979-04-05	Fremgangsmaade til fremstilling af sarcosinoxidase
DK226678A (da)	1978-11-24	Fremgangsmaade til fremstilling af hexahydrogamma-carbolinforbindelser
DK5778A (da)	1978-07-12	Femgangsmaade til fremstilling af 4-diphenylmethylen-1-hydroxybenzyl-piperidiner
DK577078A (da)	1979-06-28	Fremgangsmaade til fremstilling af trans-4a-aryloctahydro-1h-2-pyridiner
DK248978A (da)	1978-12-05	Fremgangsmaade til fremstilling af hydroxy-alfa-aminobenzylpenicillin
DK364578A (da)	1979-02-19	Fremgangsmaade til fremstilling af hydroxyphenylhydantoin
DK246878A (da)	1978-12-04	Fremgangsmaade til fremstilling af acylderivater
DK383978A (da)	1979-03-02	Fremgangsmaade til fremstilling af 2-chlorsulfinylazetidin-4-oner
DK339777A (da)	1978-10-30	Fremgangsmaade til fremstilling af 2-benzylperhydroazepiner
DK158976C (da)	1990-12-31	Fremgangsmaade til fremstilling af alfa-cyanobenzyl
DK206178A (da)	1978-11-12	Fremgangsmaade til fremstilling af 3-bromphthalid
DK195877A (da)	1978-09-16	Fremgangsmaade til fremstilling af di-n-propylacetonitril
DK147939C (da)	1985-08-26	Fremgangsmaade til fremstilling af di-n-propylacetamid