DE9414868U1 - Vascular embolization particles - Google Patents

Vascular embolization particles

Info

Publication number
DE9414868U1
DE9414868U1 DE9414868U DE9414868U DE9414868U1 DE 9414868 U1 DE9414868 U1 DE 9414868U1 DE 9414868 U DE9414868 U DE 9414868U DE 9414868 U DE9414868 U DE 9414868U DE 9414868 U1 DE9414868 U1 DE 9414868U1
Authority
DE
Germany
Prior art keywords
vascular embolization
particles
embolization particles
vascular
radiopaque
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE9414868U
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE9414868U priority Critical patent/DE9414868U1/en
Publication of DE9414868U1 publication Critical patent/DE9414868U1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/18—Materials at least partially X-ray or laser opaque
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

GebrauchsmusterProf.Dr.Günther/Dr.KIein. »»»» ."..". .**. S 09,09.1994Utility model Prof. Dr. Günther/Dr. KIein. »»»» ."..". .**. S 09,09.1994 Titel: Röntgendichte EmbolisatpartikelTitle: Radiopaque embolic particles Beschreibung:Description:

Gefäßdefekte können zu Blutverlusten oder fehlerhafter Blutverteilung mit Beeinträchtigung der SauerstoffVersorgung fuhren. Diese Defekte durch Einbringung Drahtspiralen, Gewebekleber, Ballons und Kunststoffteilchen verschlossen, 'embolisiert', werden.Vascular defects can lead to blood loss or incorrect blood distribution with impaired oxygen supply. These defects are closed, 'embolized', by inserting wire spirals, tissue adhesives, balloons and plastic particles.

Hierzu wird nach Punktion eines Gefäßes, meist in der Leistenregion, ein Katheter unmittlebar vor dem Gefäßdefekt plaziert. Über diesen wird das Embolisat injiziert, welches zum Verschluß des Gefäßdefektes fuhrt. Von großer Bedeutung für das Gelingen der Embolisation ist die Lokalisation des Embolisates durch Darstellung im Röntgendurchleuchtungsbild. Nur durch korrekte Plazierung ist der Behandlungserfolg gewährleistet, eine Fehlplazierung kann Schäden verursachen.For this, after puncturing a vessel, usually in the groin region, a catheter is placed directly in front of the vascular defect. The embolic material is injected through this, which leads to the closure of the vascular defect. The localization of the embolic material by visualizing it in the X-ray image is of great importance for the success of the embolization. The success of the treatment can only be guaranteed if it is placed correctly; incorrect placement can cause damage.

Festkörper wie Metallspiralen sind in der Regel röntgendicht. Kleber wie z.B. Histoacryl werden durch Mischung mit Kontrastmittel (z.B. Lipiodol) röntgendicht gemacht. Die häufig verwendeten Kunststoffpartikel (z.B. Polyvinylalkohol), die zum Verschluß kleiner Gefäßäste, z.B. in Gefäßtumoren, Verwendung finden, sind nicht im Röntgenbild lokalisierbar.Solid bodies such as metal spirals are usually radiopaque. Adhesives such as Histoacryl are made radiopaque by mixing them with contrast media (e.g. Lipiodol). The frequently used plastic particles (e.g. polyvinyl alcohol) that are used to close small vascular branches, e.g. in vascular tumors, cannot be localized in the X-ray image.

Aufgabe:Task:

Durch Beimischung röntgendichter Substanzen, z.B. Jod, soll die Darstellbarkeit der Kunststoffpartikel (Embolisat) im Röntgenbild erzielt werden.By adding radiopaque substances, e.g. iodine, the plastic particles (embolic material) can be visualized in the X-ray image.

Vorteile:Advantages:

Mit der Erfindung wird erreicht, daß die Kunststoffpartikel im Röntgenbild sichtbar sind und eine Kontrolle der Plazierung gewährleistet ist. Dies fuhrt zu einer Vereinfachung und höheren Sicherheit der angiographischen Embolisation.The invention ensures that the plastic particles are visible in the X-ray image and that control of their placement is ensured. This simplifies and increases the safety of angiographic embolization.

Ausführungsbeispiel:Example:

1. Mischen einer Vinylalkoholmonomerlösung mit jodhaltigem Kontrastmittel in einer Konzentration von 100 mgJ/cm3 1. Mixing a vinyl alcohol monomer solution with iodine-containing contrast medium at a concentration of 100 mgJ/cm 3

2. Polymerisation2. Polymerization

3. Zerkleinerung des Kunsstoflkörpers (Mahlen)3. Crushing of the plastic body (grinding)

4. Herstellen einer Menge von Partikeln gleicher Größe (100, 250, 500, 1000 &mgr;&pgr;&agr;).4. Prepare a quantity of particles of equal size (100, 250, 500, 1000 μπα).

Claims (1)

Schutzanspruch:Protection claim: 1. Partikel zur vaskulären Embolisation dadurch gekennzeichnet daß1. Particles for vascular embolization characterized in that sie eine Dotierung mit röntgendichten Stoffen aufweisen.they are doped with radiopaque substances.
DE9414868U 1994-09-13 1994-09-13 Vascular embolization particles Expired - Lifetime DE9414868U1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE9414868U DE9414868U1 (en) 1994-09-13 1994-09-13 Vascular embolization particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE9414868U DE9414868U1 (en) 1994-09-13 1994-09-13 Vascular embolization particles

Publications (1)

Publication Number Publication Date
DE9414868U1 true DE9414868U1 (en) 1995-02-02

Family

ID=6913647

Family Applications (1)

Application Number Title Priority Date Filing Date
DE9414868U Expired - Lifetime DE9414868U1 (en) 1994-09-13 1994-09-13 Vascular embolization particles

Country Status (1)

Country Link
DE (1) DE9414868U1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084582A1 (en) * 2002-03-29 2003-10-16 Boston Scientific Limited Embolization
US7053134B2 (en) 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
WO2011003902A2 (en) 2009-07-07 2011-01-13 Soenke Bartling Multimodal visible polymer embolization material
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US8216612B2 (en) 2004-03-02 2012-07-10 Boston Scientific Scimed, Inc. Embolization

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084582A1 (en) * 2002-03-29 2003-10-16 Boston Scientific Limited Embolization
US7053134B2 (en) 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US8216612B2 (en) 2004-03-02 2012-07-10 Boston Scientific Scimed, Inc. Embolization
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
WO2011003902A2 (en) 2009-07-07 2011-01-13 Soenke Bartling Multimodal visible polymer embolization material

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