DE3680773D1 - Isoxazolonaphthyridin-, isoxazolochinolin-, isothiazolonaphthyridin- und isothiazolochinolinderivate. - Google Patents

Isoxazolonaphthyridin-, isoxazolochinolin-, isothiazolonaphthyridin- und isothiazolochinolinderivate.

Info

Publication number
DE3680773D1
DE3680773D1 DE8686117886T DE3680773T DE3680773D1 DE 3680773 D1 DE3680773 D1 DE 3680773D1 DE 8686117886 T DE8686117886 T DE 8686117886T DE 3680773 T DE3680773 T DE 3680773T DE 3680773 D1 DE3680773 D1 DE 3680773D1
Authority
DE
Germany
Prior art keywords
isoxazolonaphthyridine
isoxazolochinoline
isothiazolonaphthyridine
isothiazolochinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686117886T
Other languages
English (en)
Inventor
Daniel Tim-Wo Chu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE3680773D1 publication Critical patent/DE3680773D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE8686117886T 1985-12-23 1986-12-22 Isoxazolonaphthyridin-, isoxazolochinolin-, isothiazolonaphthyridin- und isothiazolochinolinderivate. Expired - Fee Related DE3680773D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81266385A 1985-12-23 1985-12-23
US06/937,601 US4767762A (en) 1985-12-23 1986-12-11 Tricyclic quinoline and naphthyride antibacterials

Publications (1)

Publication Number Publication Date
DE3680773D1 true DE3680773D1 (de) 1991-09-12

Family

ID=27123652

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686117886T Expired - Fee Related DE3680773D1 (de) 1985-12-23 1986-12-22 Isoxazolonaphthyridin-, isoxazolochinolin-, isothiazolonaphthyridin- und isothiazolochinolinderivate.

Country Status (4)

Country Link
US (1) US4767762A (de)
EP (1) EP0227088B1 (de)
CA (1) CA1273631A (de)
DE (1) DE3680773D1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
FR2645862B1 (fr) * 1989-04-18 1991-07-12 Esteve Labor Dr Derives d'isothiazolo-pyrydone azetidinyl substitues, leur preparation et leur application en tant que medicaments
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
US5071848A (en) * 1989-10-23 1991-12-10 Abbott Laboratories Tricyclic quinoline antineoplastic agents
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds
ES2147721T3 (es) 1990-04-18 2000-10-01 Procter & Gamble Pharma Quinolonil lactamas antimicrobianas.
DE4035730C2 (de) * 1990-11-09 1993-10-14 Loesche Gmbh Verfahren und Vorrichtung zur Behandlung von feuchten Gas-Staub-Gemischen
US5556861A (en) * 1991-10-01 1996-09-17 Laboratoire Roger Bellon 1,8 benzonaphthyridine derivatives and antimicrobial compositions
EP0596395B1 (de) * 1992-11-04 2000-06-28 Clariant GmbH Verfahren zur Herstellung fluorierter Benzile
CN1578781A (zh) * 2001-09-26 2005-02-09 拜尔药品公司 用作抗糖尿病药物的1,8－萘啶衍生物
KR20060069836A (ko) * 2003-08-12 2006-06-22 아칠리온 파르마세우티칼스 인코포레이티드 항-감염제로서의 이소티아졸로퀴놀론 및 관련 화합물
WO2005091857A2 (en) * 2004-03-12 2005-10-06 Bayer Pharmaceuticals Corporation 1,6-naphthyridine and 1,8-naphthyridine derivatives and their use to treat diabetes and related disorders
WO2006118605A2 (en) * 2004-11-11 2006-11-09 Achillion Pharmaceuticals, Inc. 8a, 9-dihydro-4a-h-isothiazolo[5,4-b] quinoline-3, 4-diones and related compounds as anti-infective agents
US7659399B2 (en) * 2005-01-05 2010-02-09 Achillion Pharmaceuticals, Inc. 1-thia-2,4a-diaza-cyclopenta[b]napththalene-3,4-diones and related compounds as anti-infective agents
US7199128B2 (en) * 2005-02-02 2007-04-03 Achillion Pharmaceuticals, Inc. 8-N-substituted-2H-isothiazolo[5,4-b]quinolizine-3,4-diones and related compounds as antiinfective agents
BRPI0607723A2 (pt) * 2005-02-16 2009-10-06 Achillion Pharmaceuticals Inc isotiazoloquinolonas e compostos relacionados como agentes antiinfecciosos
AU2006272571B2 (en) 2005-07-27 2012-03-08 Achillion Pharmaceuticals, Inc. 8-methoxy-9H-isothiazolo[5,4-B]quinoline-3,4-diones and related compounds as anti-infective agents
WO2008036420A2 (en) * 2006-09-21 2008-03-27 Achillion Pharmaceuticals, Inc. 9-(heteroaryl)-isothiazolo[5,4-b]quinoline-3,4-diones and related compounds as anti-infective agents
WO2010115184A2 (en) * 2009-04-03 2010-10-07 Achillion Pharmaceuticals, Inc. Hydroxythienoquinolones and related compounds as anti-infective agents
WO2011031745A1 (en) * 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
JOP20190086A1 (ar) * 2016-10-21 2019-04-18 Novartis Ag مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541101A (en) * 1966-03-04 1970-11-17 Upjohn Co Isoxazolo(5,4-b)pwridines,5,6 - polymethyleneisoxazolo(5,4 - b)pyridines and processes therefor
JPS57106681A (en) * 1980-12-24 1982-07-02 Dainippon Pharmaceut Co Ltd 1,8-naphthyridine derivative and its salt
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
DE3248505A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(4- (oxoalkyl)-1-piperazinyl/-3-chinolincarbonsaeuren und ihre derivate, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4478834A (en) * 1983-02-11 1984-10-23 Usv Pharmaceutical Corporation Dihydropyridines and their use in the treatment of asthma
JPS606617A (ja) * 1983-05-09 1985-01-14 Kyorin Pharmaceut Co Ltd 抗菌性組成物
US4602014A (en) * 1984-07-09 1986-07-22 Ciba-Geigy Corporation Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators

Also Published As

Publication number Publication date
US4767762A (en) 1988-08-30
EP0227088A1 (de) 1987-07-01
CA1273631A (en) 1990-09-04
EP0227088B1 (de) 1991-08-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee