CN118707128A - A liquid adding device for blood proteome detection - Google Patents

A liquid adding device for blood proteome detection Download PDF

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CN118707128A
CN118707128A CN202410839429.3A CN202410839429A CN118707128A CN 118707128 A CN118707128 A CN 118707128A CN 202410839429 A CN202410839429 A CN 202410839429A CN 118707128 A CN118707128 A CN 118707128A
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liquid
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董芹
吴磊
张惠
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Shandong University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016Control of the volume dispensed or introduced
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers

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Abstract

本发明公开了一种血液蛋白质组检测用加液装置,涉及加液装置技术领域,其技术方案包括装置底座,装置底座外部设置有两个电动伸缩杆,电动伸缩杆外部对称固定连接有定量筒,定量筒材质透明且外部设置有刻度线,而定量筒外部设置有定量机构,通过定量机构可带动定量筒内部滑动连接的推液板发生移动,本发明中,通过设置在电动伸缩杆外部的定量机构可带动推液板在定量筒内进行移动,而通过控制推液板使其停留在不同的刻度位置,可对定量筒内能够通入的液体总量进行控制,从而达到定量加液的目的,通过提前的设定使得装置在加液过程中无需人员再观察确认,提高了装置的使用效果,而且装置还可同时对两个容器内进行加液,保证了装置的工作效率。

The present invention discloses a liquid adding device for blood proteome detection, and relates to the technical field of liquid adding devices. Its technical scheme includes a device base, two electric telescopic rods are arranged on the outside of the device base, and a quantitative cylinder is symmetrically fixedly connected to the outside of the electric telescopic rod. The quantitative cylinder is made of a transparent material and has scale lines arranged on the outside, and a quantitative mechanism is arranged on the outside of the quantitative cylinder, and the quantitative mechanism can drive a liquid pushing plate slidably connected to the inside of the quantitative cylinder to move. In the present invention, the liquid pushing plate can be driven to move in the quantitative cylinder by the quantitative mechanism arranged on the outside of the electric telescopic rod, and the liquid pushing plate can be controlled to stay at different scale positions by controlling the liquid pushing plate to control the total amount of liquid that can be introduced into the quantitative cylinder, thereby achieving the purpose of quantitative liquid addition. Through advance setting, the device does not need to be observed and confirmed by personnel during the liquid addition process, thereby improving the use effect of the device, and the device can also add liquid to two containers at the same time, thereby ensuring the working efficiency of the device.

Description

一种血液蛋白质组检测用加液装置A liquid adding device for blood proteome detection

技术领域Technical Field

本发明涉及加液装置技术领域,尤其涉及一种血液蛋白质组检测用加液装置。The invention relates to the technical field of liquid adding devices, in particular to a liquid adding device for blood proteome detection.

背景技术Background Art

血液蛋白质组检测是一项重要的生物学分析技术,可以通过分析血液中的蛋白质组成来了解人体的健康状况,然而,传统的蛋白质组检测方法存在一些限制,包括样本处理过程中的蛋白质丢失以及复杂的操作流程,为了克服这些问题,加液装置被引入到血液蛋白质组检测中,加液装置进行血液蛋白质组检测能够大大提高检测效率和准确性,缩短分析时间,并且减少了人工操作的错误和变异性,此外,加液装置的自动化特性使得操作更加简便,即使是无经验的操作员也可以轻松地进行检测,这使得血液蛋白质组检测更加广泛应用于疾病诊断、药物研发和个体化医学等领域,Blood proteome testing is an important biological analysis technology that can be used to understand the health status of the human body by analyzing the protein composition in the blood. However, traditional proteome testing methods have some limitations, including protein loss during sample processing and complex operating procedures. In order to overcome these problems, liquid adding devices have been introduced into blood proteome testing. Blood proteome testing with liquid adding devices can greatly improve detection efficiency and accuracy, shorten analysis time, and reduce errors and variability in manual operations. In addition, the automation characteristics of the liquid adding device make the operation easier, and even inexperienced operators can easily perform the test, which makes blood proteome testing more widely used in disease diagnosis, drug development, and personalized medicine.

经检索,中国专利号CN202220522840.4的专利,公开了一种血液蛋白质组检测用加液装置,包括底板,底板的顶部对称固定连接有立板,立板的外侧滑动连接有移动板,移动板的顶部对称固定连接有挡板,挡板的外侧固定连接有限位板,限位板的内部等距开设有多个通槽,底板的顶部等距固定连接有多个支撑杆,支撑杆的顶部固定连接有顶板,顶板的底部对称固定连接有固定杆,固定杆的外侧滑动连接有压板,压板的底部等距设有多个出液管,本装置达到的有益效果是:对容器进行挤压固定,能够防止容器在输入液体的过程中发生倾斜;能够一次进行多瓶液体输入,有效提高工作人员的工作效率。与现有技术相比,该中国专利号为CN202220522840.4的专利以解决现有技术中血液蛋白质组检测用加液装置在液体输入过程中,瓶身容易发生倾斜,导致工作人员的工作效率较低的问题。After searching, the Chinese patent number CN202220522840.4 discloses a liquid adding device for blood proteome detection, including a bottom plate, a vertical plate is symmetrically fixedly connected to the top of the bottom plate, a movable plate is slidably connected to the outer side of the vertical plate, a baffle is symmetrically fixedly connected to the top of the movable plate, a limit plate is fixedly connected to the outer side of the baffle, a plurality of through grooves are equidistantly provided inside the limit plate, a plurality of support rods are equidistantly fixedly connected to the top of the bottom plate, a top plate is fixedly connected to the top of the support rod, a fixed rod is symmetrically fixedly connected to the bottom of the top plate, a pressure plate is slidably connected to the outer side of the fixed rod, and a plurality of liquid outlet pipes are equidistantly provided at the bottom of the pressure plate. The beneficial effects achieved by the device are: the container is squeezed and fixed to prevent the container from tilting during the liquid input process; multiple bottles of liquid can be input at one time, effectively improving the work efficiency of the staff. Compared with the prior art, the Chinese patent number CN202220522840.4 solves the problem that the bottle of the liquid adding device for blood proteome detection in the prior art is prone to tilt during the liquid input process, resulting in low work efficiency of the staff.

但上述装置在实际的使用过程中,装置通过电磁阀控制液体输入容器时人员还需要时刻盯紧容器内的液体刻度才能对输入液体定量,过程较为繁琐,且容易出现误差不便于使用,因此,提出一种血液蛋白质组检测用加液装置。However, in actual use of the above device, when the device controls the liquid input into the container through the solenoid valve, the personnel need to keep an eye on the liquid scale in the container to quantify the input liquid. The process is cumbersome, prone to errors and inconvenient to use. Therefore, a liquid adding device for blood proteome detection is proposed.

发明内容Summary of the invention

本发明的目的是为了解决现有技术中,装置通过电磁阀控制液体输入容器时人员还需要时刻盯紧容器内的液体刻度才能对输入液体定量,过程较为繁琐,且容易出现误差不便于使用的缺点,而提出的一种血液蛋白质组检测用加液装置。The purpose of the present invention is to solve the shortcomings of the prior art that when the device controls the liquid input into the container through an electromagnetic valve, the personnel need to keep an eye on the liquid scale in the container to quantify the input liquid. The process is cumbersome, prone to errors and inconvenient to use. A liquid adding device for blood proteome detection is proposed.

为了实现上述目的,本发明采用了如下技术方案:In order to achieve the above object, the present invention adopts the following technical solutions:

一种血液蛋白质组检测用加液装置,包括装置底座,所述装置底座外部设置有两个电动伸缩杆,所述电动伸缩杆外部对称固定连接有定量筒,所述定量筒材质透明且外部设置有刻度线,而定量筒外部设置有定量机构,通过定量机构可带动定量筒内部滑动连接的推液板发生移动,通过将推液板移动到刻度线的不同位置可对液体定量;A liquid adding device for blood proteome detection, comprising a device base, two electric telescopic rods are arranged outside the device base, and a quantitative cylinder is symmetrically fixedly connected to the outside of the electric telescopic rod. The quantitative cylinder is made of transparent material and has scale lines arranged outside, and a quantitative mechanism is arranged outside the quantitative cylinder. The quantitative mechanism can drive a liquid pushing plate slidably connected inside the quantitative cylinder to move, and the liquid can be quantified by moving the liquid pushing plate to different positions of the scale lines;

所述电动伸缩杆外部设置有储液箱,所述储液箱外部连通有两个入液管,所述入液管外部远离储液箱一侧固定连接有控制阀,所述控制阀又与推液板连通,所述控制阀内设置有控制组件,通过控制组件控制控制阀开启可使储液箱内的液体通过入液管流入定量筒内,而需要加液时,通过控制组件关闭控制阀即可。A liquid storage tank is arranged outside the electric telescopic rod, and two liquid inlet pipes are connected to the outside of the liquid storage tank. A control valve is fixedly connected to the side of the liquid inlet pipe away from the liquid storage tank. The control valve is connected to the liquid push plate. A control component is arranged inside the control valve. The control valve is opened by the control component to allow the liquid in the liquid storage tank to flow into the quantitative cylinder through the liquid inlet pipe. When liquid needs to be added, the control valve can be closed by the control component.

上述技术方案进一步包括:The above technical solution further includes:

所述定量机构包括设置在电动伸缩杆外部的推液壳体,所述推液壳体内部设置有第二电机,所述第二电机外部输出端设置有定量组件。The quantitative mechanism comprises a liquid pushing housing arranged outside the electric telescopic rod, a second motor is arranged inside the liquid pushing housing, and a quantitative component is arranged at an external output end of the second motor.

所述定量组件包括第二电机外部输出端设置的蜗杆,所述蜗杆外部转动连接有推液壳体,所述蜗杆外部啮合连接有蜗轮,所述蜗轮外部转动连接有推液壳体,所述蜗轮外部固定连接有第三齿轮,所述第三齿轮外部啮合连接有第一齿条,所述第一齿条外部固定连接有推液板。The quantitative component includes a worm arranged at the external output end of the second motor, the external part of the worm is rotatably connected to a liquid pushing housing, the external part of the worm is meshedly connected to a worm wheel, the external part of the worm wheel is rotatably connected to the liquid pushing housing, the external part of the worm wheel is fixedly connected to a third gear, the external part of the third gear is meshedly connected to a first rack, and the external part of the first rack is fixedly connected to a liquid pushing plate.

所述推液壳体内部固定连接有传动滑槽,所述传动滑槽内部滑动连接有第一齿条。A transmission slide groove is fixedly connected inside the liquid pushing housing, and a first rack is slidably connected inside the transmission slide groove.

所述控制组件包括控制阀内部设置的第三电机,所述第三电机外部输出端设置有第四齿轮,所述第四齿轮外部对称啮合连接有第二齿条,所述第二齿条外部固定连接有连接杆,所述连接杆外部固定连接有活动挡板,所述活动挡板外部滑动连接有控制阀。The control component includes a third motor arranged inside the control valve, a fourth gear is arranged at the external output end of the third motor, a second rack is symmetrically meshedly connected to the outside of the fourth gear, a connecting rod is fixedly connected to the outside of the second rack, a movable baffle is fixedly connected to the outside of the connecting rod, and a control valve is slidably connected to the outside of the movable baffle.

所述装置底座外部设置有两个夹持机构,通过夹持机构可对容器进行夹持固定,而固定位置就位于定量筒的正下方。Two clamping mechanisms are arranged outside the base of the device, and the container can be clamped and fixed by the clamping mechanisms, and the fixing position is located just below the quantitative cylinder.

所述夹持组件包括固定连接在装置底座外部的夹持架,所述夹持架内部设置有第一电机,所述第一电机外部输出端设置有夹持组件。The clamping assembly comprises a clamping frame fixedly connected to the outside of the device base, a first motor is arranged inside the clamping frame, and a clamping assembly is arranged at an external output end of the first motor.

所述夹持组件包括第一电机外部输出端设置的第一齿轮,所述第一齿轮外部啮合连接有第一夹持件,所述第一夹持件外部转动连接有夹持架,所述第一夹持件外部设置有橡胶防滑齿。The clamping assembly includes a first gear disposed at the external output end of the first motor, the first gear is externally meshedly connected with a first clamping member, the first clamping member is externally rotatably connected with a clamping frame, and the first clamping member is externally provided with rubber anti-slip teeth.

所述第一齿轮外部固定连接有第二齿轮,所述第二齿轮外部转动连接有夹持架,所述第二齿轮外部啮合连接有第二夹持件,所述第二夹持件外部转动连接有夹持架,所述第二夹持件外部固定连接有橡胶防滑齿。The first gear is fixedly connected to the outside with a second gear, the second gear is rotatably connected to the outside with a clamping frame, the second gear is meshingly connected to the outside with a second clamping piece, the second clamping piece is rotatably connected to the outside with a clamping frame, and the second clamping piece is fixedly connected to the outside with rubber anti-slip teeth.

所本发明具备以下有益效果:The present invention has the following beneficial effects:

1、本发明中,使用时,通过设置在电动伸缩杆外部的定量机构可带动推液板在定量筒内进行移动,而通过控制推液板使其停留在不同的刻度位置,可对定量筒内能够通入的液体总量进行控制,从而达到定量加液的目的,通过提前的设定使得装置在加液过程中无需人员再观察确认,提高了装置的使用效果,而且装置还可同时对两个容器内进行加液,保证了装置的工作效率。1. In the present invention, when in use, the quantitative mechanism arranged on the outside of the electric telescopic rod can drive the liquid pushing plate to move in the quantitative cylinder, and by controlling the liquid pushing plate to stay at different scale positions, the total amount of liquid that can be introduced into the quantitative cylinder can be controlled, thereby achieving the purpose of quantitative liquid addition. Through advance settings, the device does not need personnel to observe and confirm during the liquid addition process, which improves the use effect of the device. In addition, the device can also add liquid to two containers at the same time, ensuring the working efficiency of the device.

2、本发明中,使用时,将容器放置在第一夹持件个第二夹持件的中间后,通过夹持组件即可带动第一夹持件和第二夹持件向内闭合,从而将位于中间的容器夹持固定,可有效保证容器在加液过程中保持稳定,不会出现倾斜从而导致液体流出,而设置在第一夹持件和第二夹持件外部的橡胶防滑齿还可进一步提高容器与第一夹持件和第二夹持件间的摩擦,而且橡胶防滑齿材质柔软可以在夹持过程中保证容器不会受到损伤。2. In the present invention, when in use, after placing the container between the first clamping member and the second clamping member, the first clamping member and the second clamping member can be driven to close inward through the clamping assembly, so as to clamp and fix the container located in the middle, which can effectively ensure that the container remains stable during the liquid adding process and will not tilt to cause liquid to flow out. The rubber anti-slip teeth arranged on the outside of the first clamping member and the second clamping member can further increase the friction between the container and the first clamping member and the second clamping member, and the rubber anti-slip teeth are soft in material and can ensure that the container will not be damaged during the clamping process.

附图说明BRIEF DESCRIPTION OF THE DRAWINGS

图1为本发明提出的一种血液蛋白质组检测用加液装置的结构示意图;FIG1 is a schematic structural diagram of a liquid adding device for blood proteome detection proposed by the present invention;

图2为本发明中的立体结构示意图;FIG2 is a schematic diagram of a three-dimensional structure of the present invention;

图3为本发明中的第一结构示意图;FIG3 is a schematic diagram of a first structure of the present invention;

图4为本发明中的第二结构示意图;FIG4 is a schematic diagram of a second structure of the present invention;

图5为本发明中的第三结构示意图;FIG5 is a schematic diagram of a third structure of the present invention;

图6为本发明中的第四结构示意图;FIG6 is a schematic diagram of a fourth structure of the present invention;

图7为本发明中的第五结构示意图;FIG7 is a schematic diagram of a fifth structure of the present invention;

图8为本发明中的第六结构示意图。FIG8 is a sixth structural diagram of the present invention.

图中:1、装置底座;2、储液箱;3、电动伸缩杆;4、容器;5、定量筒;6、夹持架;7、第一电机;8、第一齿轮;9、第二齿轮;10、第一夹持件;11、第二夹持件;12、橡胶防滑齿;13、入液管;14、推液壳体;15、控制阀;16、第一齿条;17、推液板;18、第二电机;19、蜗杆;20、蜗轮;21、第三齿轮;22、第三电机;23、第四齿轮;24、第二齿条;25、连接杆;26、活动挡板;27、传动滑槽。In the figure: 1. device base; 2. liquid storage tank; 3. electric telescopic rod; 4. container; 5. quantitative cylinder; 6. clamping frame; 7. first motor; 8. first gear; 9. second gear; 10. first clamping member; 11. second clamping member; 12. rubber anti-skid teeth; 13. liquid inlet pipe; 14. liquid pushing shell; 15. control valve; 16. first rack; 17. liquid pushing plate; 18. second motor; 19. worm; 20. worm wheel; 21. third gear; 22. third motor; 23. fourth gear; 24. second rack; 25. connecting rod; 26. movable baffle; 27. transmission slide.

具体实施方式DETAILED DESCRIPTION

下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

实施例一Embodiment 1

如图1-图8所示,本发明提出的一种血液蛋白质组检测用加液装置,包括装置底座1,装置底座1外部设置有两个电动伸缩杆3,电动伸缩杆3外部对称固定连接有定量筒5,定量筒5材质透明且外部设置有刻度线,而定量筒5外部设置有定量机构,通过定量机构可带动定量筒5内部滑动连接的推液板17发生移动,通过将推液板17移动到刻度线的不同位置可对液体定量;As shown in Fig. 1 to Fig. 8, a liquid adding device for blood proteome detection proposed by the present invention comprises a device base 1, two electric telescopic rods 3 are arranged outside the device base 1, and a quantitative cylinder 5 is symmetrically fixedly connected to the outside of the electric telescopic rod 3. The quantitative cylinder 5 is made of transparent material and has scale lines arranged on the outside, and a quantitative mechanism is arranged on the outside of the quantitative cylinder 5. The quantitative mechanism can drive a liquid pushing plate 17 slidably connected to the inside of the quantitative cylinder 5 to move, and the liquid can be quantified by moving the liquid pushing plate 17 to different positions of the scale lines;

电动伸缩杆3外部设置有储液箱2,储液箱2外部连通有两个入液管13,入液管13外部远离储液箱2一侧固定连接有控制阀15,控制阀15又与推液板17连通,控制阀15内设置有控制组件,通过控制组件控制控制阀15开启可使储液箱2内的液体通过入液管13流入定量筒5内,而需要加液时,通过控制组件关闭控制阀15即可;A liquid storage tank 2 is arranged outside the electric telescopic rod 3, and two liquid inlet pipes 13 are connected to the outside of the liquid storage tank 2. A control valve 15 is fixedly connected to the side of the liquid inlet pipe 13 away from the liquid storage tank 2. The control valve 15 is connected to the liquid push plate 17. A control component is arranged inside the control valve 15. The control component controls the control valve 15 to open so that the liquid in the liquid storage tank 2 can flow into the quantitative cylinder 5 through the liquid inlet pipe 13. When liquid needs to be added, the control valve 15 can be closed by the control component.

定量机构包括设置在电动伸缩杆3外部的推液壳体14,推液壳体14内部设置有第二电机18,第二电机18外部输出端设置有定量组件;The quantitative mechanism includes a liquid pushing housing 14 arranged outside the electric telescopic rod 3, a second motor 18 is arranged inside the liquid pushing housing 14, and a quantitative component is arranged at the external output end of the second motor 18;

定量组件包括第二电机18外部输出端设置的蜗杆19,蜗杆19外部转动连接有推液壳体14,蜗杆19外部啮合连接有蜗轮20,蜗轮20外部转动连接有推液壳体14,蜗轮20外部固定连接有第三齿轮21,第三齿轮21外部啮合连接有第一齿条16,第一齿条16外部固定连接有推液板17;The quantitative component includes a worm 19 arranged at the external output end of the second motor 18, the worm 19 is externally rotatably connected to the liquid pushing housing 14, the worm 19 is externally meshedly connected to the worm wheel 20, the worm wheel 20 is externally rotatably connected to the liquid pushing housing 14, the worm wheel 20 is externally fixedly connected to the third gear 21, the third gear 21 is externally meshedly connected to the first rack 16, and the first rack 16 is externally fixedly connected to the liquid pushing plate 17;

推液壳体14内部固定连接有传动滑槽27,传动滑槽27内部滑动连接有第一齿条16;A transmission slide 27 is fixedly connected inside the liquid pushing housing 14, and a first rack 16 is slidably connected inside the transmission slide 27;

控制组件包括控制阀15内部设置的第三电机22,第三电机22外部输出端设置有第四齿轮23,第四齿轮23外部对称啮合连接有第二齿条24,第二齿条24外部固定连接有连接杆25,连接杆25外部固定连接有活动挡板26,活动挡板26外部滑动连接有控制阀15。The control component includes a third motor 22 arranged inside the control valve 15, a fourth gear 23 is arranged at the external output end of the third motor 22, the fourth gear 23 is symmetrically meshed with a second rack 24 on the outside, the second rack 24 is fixedly connected to a connecting rod 25 on the outside, the connecting rod 25 is fixedly connected to a movable baffle 26 on the outside, and the movable baffle 26 is slidably connected to the control valve 15 on the outside.

本实施例中,使用时,首先将容器4通过夹持机构固定,接着打开推液壳体14内部的第二电机18,通过第二电机18可带动蜗杆19发生转动,蜗杆19转动可带动啮合连接的蜗轮20转动,蜗轮20转动可带动固定连接的第三齿轮21发生转动,第三齿轮21转动可带动啮合连接的第一齿条16进行移动,而第一齿条16的外部滑动连接有传动滑槽27,通过传动滑槽27可保证第一齿条16移动时的稳定,而第一齿条16移动可带动推液板17在定量筒5内部滑动,通过控制推液板17使其停留在不同的刻度位置,可对定量筒5内能够通入的液体总量进行控制,从而达到定量加液的目的,装置通过提前的设定使得装置在加液过程中无需人员再观察确认,提高了装置的使用效果;In the present embodiment, when in use, the container 4 is first fixed by the clamping mechanism, and then the second motor 18 inside the liquid pushing housing 14 is turned on, and the worm 19 can be driven to rotate by the second motor 18, and the rotation of the worm 19 can drive the meshing worm wheel 20 to rotate, and the rotation of the worm wheel 20 can drive the fixedly connected third gear 21 to rotate, and the rotation of the third gear 21 can drive the meshing first rack 16 to move, and the outer sliding connection of the first rack 16 is connected with a transmission slide 27, and the stability of the first rack 16 during movement can be ensured by the transmission slide 27, and the movement of the first rack 16 can drive the liquid pushing plate 17 to slide inside the quantitative cylinder 5, and by controlling the liquid pushing plate 17 to stay at different scale positions, the total amount of liquid that can be introduced into the quantitative cylinder 5 can be controlled, thereby achieving the purpose of quantitative liquid addition, and the device is set in advance so that the device does not need to be observed and confirmed by personnel during the liquid addition process, thereby improving the use effect of the device;

定量完成后,通过电动伸缩杆3可带动两个定量筒5向下移动,从而逐渐与位于正下方的容器4接近,当定量筒5的前端进入容器4内后,控制控制阀15内部设置的第三电机22带动第四齿轮23发生转动,第四齿轮23转动可带动对称啮合连接的第二齿条24发生移动,而第二齿条24移动可带动通过连接杆25固定连接的活动挡板26发生移动,所以通过第三电机22可控制控制阀15的开启与关闭,通过第三电机22控制控制阀15开启使得储液箱2内的液体可以通过入液管13流入定量筒5内,当液体灌满定量筒5后,通过第三电机22控制控制阀15关闭,之后只需要控制推液板17向下移动即可将定量的液体输入到容器4内。After the quantitative measurement is completed, the two quantitative cylinders 5 can be driven to move downward by the electric telescopic rod 3, so as to gradually approach the container 4 located directly below. When the front end of the quantitative cylinder 5 enters the container 4, the third motor 22 arranged inside the control valve 15 drives the fourth gear 23 to rotate. The rotation of the fourth gear 23 can drive the second rack 24 symmetrically meshingly connected to move, and the movement of the second rack 24 can drive the movable baffle 26 fixedly connected by the connecting rod 25 to move. Therefore, the opening and closing of the control valve 15 can be controlled by the third motor 22. The control valve 15 is opened by the third motor 22 so that the liquid in the liquid storage tank 2 can flow into the quantitative cylinder 5 through the liquid inlet pipe 13. When the liquid fills the quantitative cylinder 5, the control valve 15 is closed by the third motor 22. After that, it is only necessary to control the liquid pushing plate 17 to move downward to input the quantitative liquid into the container 4.

实施例二Embodiment 2

如图1-图8所示,基于实施例一的基础上,装置底座1外部设置有两个夹持机构,通过夹持机构可对容器4进行夹持固定,而固定位置就位于定量筒5的正下方;As shown in FIG. 1 to FIG. 8 , based on the first embodiment, two clamping mechanisms are provided outside the device base 1 , through which the container 4 can be clamped and fixed, and the fixing position is located directly below the quantitative cylinder 5;

夹持组件包括固定连接在装置底座1外部的夹持架6,夹持架6内部设置有第一电机7,第一电机7外部输出端设置有夹持组件;The clamping assembly includes a clamping frame 6 fixedly connected to the outside of the device base 1, a first motor 7 is arranged inside the clamping frame 6, and a clamping assembly is arranged at the external output end of the first motor 7;

夹持组件包括第一电机7外部输出端设置的第一齿轮8,第一齿轮8外部啮合连接有第一夹持件10,第一夹持件10外部转动连接有夹持架6,第一夹持件10外部设置有橡胶防滑齿12;The clamping assembly includes a first gear 8 disposed at the external output end of the first motor 7, the first gear 8 is externally meshed and connected with a first clamping member 10, the first clamping member 10 is externally rotatably connected with a clamping frame 6, and the first clamping member 10 is externally provided with rubber anti-slip teeth 12;

第一齿轮8外部固定连接有第二齿轮9,第二齿轮9外部转动连接有夹持架6,第二齿轮9外部啮合连接有第二夹持件11,第二夹持件11外部转动连接有夹持架6,第二夹持件11外部固定连接有橡胶防滑齿12。The first gear 8 is fixedly connected to the outside of the second gear 9, which is rotatably connected to the clamping frame 6, and the second gear 9 is meshingly connected to the outside of the second clamping member 11, which is rotatably connected to the clamping frame 6, and the second clamping member 11 is fixedly connected to the outside of the rubber anti-skid teeth 12.

本实施例中,使用前,首先将容器4放置在第一夹持件10和第二夹持件11中间的位置,接着通过第一电机7带动第一齿轮8个第二齿轮9发生转动,第一齿轮8和第二齿轮9转动可带动啮合连接的第一夹持件10和第二夹持件11也发生转动,从而使第一夹持件10和第二夹持件11向内转动闭合,将位于中间的容器4夹持固定,有效保证了容器4在加液过程中的稳定性,避免了容器4发生倾斜从而导致液体流出的情况出现,而设置在第一夹持件10和第二夹持件11外部的橡胶防滑齿12还可进一步提高容器4与第一夹持件10和第二夹持件11间的摩擦,使容器4的稳定性得到提升,而且橡胶防滑齿12材质柔软可以在夹持过程中保证容器4不会受到损伤。In this embodiment, before use, the container 4 is first placed in the middle of the first clamping member 10 and the second clamping member 11, and then the first motor 7 drives the first gear 8 and the second gear 9 to rotate. The rotation of the first gear 8 and the second gear 9 can drive the meshing first clamping member 10 and the second clamping member 11 to rotate, so that the first clamping member 10 and the second clamping member 11 are rotated inward and closed, clamping and fixing the container 4 located in the middle, effectively ensuring the stability of the container 4 during the liquid adding process, and avoiding the container 4 from tilting and causing the liquid to flow out. The rubber anti-slip teeth 12 arranged on the outside of the first clamping member 10 and the second clamping member 11 can further increase the friction between the container 4 and the first clamping member 10 and the second clamping member 11, so that the stability of the container 4 is improved, and the rubber anti-slip teeth 12 are made of a soft material to ensure that the container 4 will not be damaged during the clamping process.

尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变形,本发明的范围由所附权利要求及其等同物限定。Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims (9)

1.一种血液蛋白质组检测用加液装置,包括装置底座(1),其特征在于,所述装置底座(1)外部设置有两个电动伸缩杆(3),所述电动伸缩杆(3)外部对称固定连接有定量筒(5),所述定量筒(5)材质透明且外部设置有刻度线,而定量筒(5)外部设置有定量机构,通过定量机构可带动定量筒(5)内部滑动连接的推液板(17)发生移动,通过将推液板(17)移动到刻度线的不同位置可对液体定量;1. A liquid adding device for blood proteome detection, comprising a device base (1), characterized in that two electric telescopic rods (3) are arranged outside the device base (1), and a quantitative cylinder (5) is symmetrically fixedly connected to the outside of the electric telescopic rod (3), the quantitative cylinder (5) is made of transparent material and has scale lines arranged on the outside, and a quantitative mechanism is arranged on the outside of the quantitative cylinder (5), and a liquid pushing plate (17) slidably connected to the inside of the quantitative cylinder (5) can be driven to move by the quantitative mechanism, and the liquid can be quantified by moving the liquid pushing plate (17) to different positions of the scale lines; 所述电动伸缩杆(3)外部设置有储液箱(2),所述储液箱(2)外部连通有两个入液管(13),所述入液管(13)外部远离储液箱(2)一侧固定连接有控制阀(15),所述控制阀(15)又与推液板(17)连通,所述控制阀(15)内设置有控制组件,通过控制组件控制控制阀(15)开启可使储液箱(2)内的液体通过入液管(13)流入定量筒(5)内,而需要加液时,通过控制组件关闭控制阀(15)即可。The electric telescopic rod (3) is provided with a liquid storage tank (2) outside, and the liquid storage tank (2) is connected to two liquid inlet pipes (13) outside. A control valve (15) is fixedly connected to the side of the liquid inlet pipe (13) outside the liquid storage tank (2), and the control valve (15) is connected to a liquid push plate (17). A control component is provided inside the control valve (15). The control component controls the control valve (15) to open so that the liquid in the liquid storage tank (2) can flow into the quantitative cylinder (5) through the liquid inlet pipe (13). When liquid needs to be added, the control valve (15) can be closed by the control component. 2.根据权利要求1所述的一种血液蛋白质组检测用加液装置,其特征在于,所述定量机构包括设置在电动伸缩杆(3)外部的推液壳体(14),所述推液壳体(14)内部设置有第二电机(18),所述第二电机(18)外部输出端设置有定量组件。2. A liquid adding device for blood proteome detection according to claim 1, characterized in that the quantitative mechanism includes a liquid pushing shell (14) arranged outside the electric telescopic rod (3), a second motor (18) is arranged inside the liquid pushing shell (14), and a quantitative component is arranged at the external output end of the second motor (18). 3.根据权利要求2所述的一种血液蛋白质组检测用加液装置,其特征在于,所述定量组件包括第二电机(18)外部输出端设置的蜗杆(19),所述蜗杆(19)外部转动连接有推液壳体(14),所述蜗杆(19)外部啮合连接有蜗轮(20),所述蜗轮(20)外部转动连接有推液壳体(14),所述蜗轮(20)外部固定连接有第三齿轮(21),所述第三齿轮(21)外部啮合连接有第一齿条(16),所述第一齿条(16)外部固定连接有推液板(17)。3. A liquid adding device for blood proteome detection according to claim 2, characterized in that the quantitative component includes a worm (19) arranged at the external output end of the second motor (18), the worm (19) is externally rotatably connected to a liquid pushing housing (14), the worm (19) is externally meshedly connected to a worm wheel (20), the worm wheel (20) is externally rotatably connected to the liquid pushing housing (14), the worm wheel (20) is externally fixedly connected to a third gear (21), the third gear (21) is externally meshedly connected to a first rack (16), and the first rack (16) is externally fixedly connected to a liquid pushing plate (17). 4.根据权利要求2所述的一种血液蛋白质组检测用加液装置,其特征在于,所述推液壳体(14)内部固定连接有传动滑槽(27),所述传动滑槽(27)内部滑动连接有第一齿条(16)。4. A liquid adding device for blood proteome detection according to claim 2, characterized in that a transmission slide groove (27) is fixedly connected inside the liquid pushing housing (14), and a first rack (16) is slidably connected inside the transmission slide groove (27). 5.根据权利要求1所述的一种血液蛋白质组检测用加液装置,其特征在于,所述控制组件包括控制阀(15)内部设置的第三电机(22),所述第三电机(22)外部输出端设置有第四齿轮(23),所述第四齿轮(23)外部对称啮合连接有第二齿条(24),所述第二齿条(24)外部固定连接有连接杆(25),所述连接杆(25)外部固定连接有活动挡板(26),所述活动挡板(26)外部滑动连接有控制阀(15)。5. A liquid adding device for blood proteome detection according to claim 1, characterized in that the control component includes a third motor (22) arranged inside the control valve (15), a fourth gear (23) is arranged at the external output end of the third motor (22), the fourth gear (23) is symmetrically meshed with a second rack (24) on the outside, the second rack (24) is fixedly connected to a connecting rod (25) on the outside, the connecting rod (25) is fixedly connected to a movable baffle (26) on the outside, and the movable baffle (26) is slidably connected to the control valve (15) on the outside. 6.根据权利要求1所述的一种血液蛋白质组检测用加液装置,其特征在于,所述装置底座(1)外部设置有两个夹持机构,通过夹持机构可对容器(4)进行夹持固定,而固定位置就位于定量筒(5)的正下方。6. A liquid adding device for blood proteome detection according to claim 1, characterized in that two clamping mechanisms are arranged outside the device base (1), and the container (4) can be clamped and fixed by the clamping mechanisms, and the fixing position is located directly below the quantitative cylinder (5). 7.根据权利要求6所述的一种血液蛋白质组检测用加液装置,其特征在于,所述夹持组件包括固定连接在装置底座(1)外部的夹持架(6),所述夹持架(6)内部设置有第一电机(7),所述第一电机(7)外部输出端设置有夹持组件。7. A liquid adding device for blood proteome detection according to claim 6, characterized in that the clamping assembly includes a clamping frame (6) fixedly connected to the outside of the device base (1), a first motor (7) is arranged inside the clamping frame (6), and a clamping assembly is arranged at the external output end of the first motor (7). 8.根据权利要求7所述的一种血液蛋白质组检测用加液装置,其特征在于,所述夹持组件包括第一电机(7)外部输出端设置的第一齿轮(8),所述第一齿轮(8)外部啮合连接有第一夹持件(10),所述第一夹持件(10)外部转动连接有夹持架(6),所述第一夹持件(10)外部设置有橡胶防滑齿(12)。8. A liquid adding device for blood proteome detection according to claim 7, characterized in that the clamping assembly includes a first gear (8) arranged at the external output end of the first motor (7), the first gear (8) is externally meshedly connected to a first clamping member (10), the first clamping member (10) is externally rotatably connected to a clamping frame (6), and the first clamping member (10) is externally provided with rubber anti-slip teeth (12). 9.根据权利要求8所述的一种血液蛋白质组检测用加液装置,其特征在于,所述第一齿轮(8)外部固定连接有第二齿轮(9),所述第二齿轮(9)外部转动连接有夹持架(6),所述第二齿轮(9)外部啮合连接有第二夹持件(11),所述第二夹持件(11)外部转动连接有夹持架(6),所述第二夹持件(11)外部固定连接有橡胶防滑齿(12)。9. A liquid adding device for blood proteome detection according to claim 8, characterized in that the first gear (8) is fixedly connected to the outside of the second gear (9), the second gear (9) is rotatably connected to the outside of the clamping frame (6), the second gear (9) is meshingly connected to the outside of the second clamping piece (11), the second clamping piece (11) is rotatably connected to the outside of the clamping frame (6), and the second clamping piece (11) is fixedly connected to the outside of the rubber anti-slip teeth (12).
CN202410839429.3A 2024-06-26 2024-06-26 A liquid adding device for blood proteome detection Pending CN118707128A (en)

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CN119186671A (en) * 2024-11-14 2024-12-27 江苏医药职业学院 Quantitative instrument for cardiovascular pharmacology experiment

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