CN114788745A - Anti-embolism carotid artery forming system - Google Patents

Abstract

The invention discloses an anti-embolism carotid angioplasty system, comprising a stent delivery sheath, a self-expanding stent and a stent advancing catheter. The stent delivery sheath has a proximal end, a distal end and an inner cavity; the self-expanding stent has an unexpanded state and expanded state; the stent advancing catheter should have a catheter shaft, and an expandable member is installed at the distal end of the catheter shaft; the stent delivery sheath is provided with the stent advancing catheter, and the stent advancing catheter is sleeved with matching sliding block. The beneficial effects are as follows: in the treatment of carotid artery stenosis, the stent implantation can be protected by the integrated expansion stent filter, and the operation is simple and convenient. , expanding the gas permeable membrane in the stent provides more effective fixation for the expanded gas permeable membrane, and simplifies the catheter operation in the subsequent steps.

Description

An anti-embolic carotid angioplasty system

technical field

The invention relates to the technical field of interventional treatment of vascular diseases, in particular to an anti-embolism carotid arterioplasty system.

Background technique

Catheters based on treatments including angioplasty and stenting have shown surprising advances in the treatment of infarct vascular disease. In 1974, Gruentzig et al. first reported percutaneous transluminal angioplasty using a balloon dilatation catheter for the treatment of peripheral arterial stenosis.

Despite the amazing progress this technology has made, many problems and difficulties remain in the use of angioplasty and stenting to treat carotid artery disease. Specifically, manipulation of the catheter in the carotid artery may dislodge embolic material, such as thrombotic material and atherosclerotic plaque, which are carried distally by the bloodstream into the cerebral vasculature and cause ischemic damage to the brain Currently available distal embolic protection devices for performing carotid-protective angioplasty and stenting include filter devices for capturing potential emboli and occlusion balloon catheters combined with suction for removal of potential emboli . Commercially available systems tend to be expensive and somewhat cumbersome to use. Another disadvantage of using a distal embolic protection device is that placing the device distally relative to the treatment site tends to induce spasm of the distal internal carotid artery, which can sometimes lead to serious complications. Other approaches, such as proximal occlusion of the carotid artery, have still not shown effectiveness in reducing embolic complications.

For the problems in the related technologies, no effective solutions have been proposed so far.

SUMMARY OF THE INVENTION

In view of the problems in the related art, the present invention proposes an anti-embolism carotid angioplasty system to overcome the above-mentioned technical problems existing in the related art.

For this reason, the concrete technical scheme that the present invention adopts is as follows:

An anti-embolism carotid angioplasty system, comprising a stent delivery sheath, a self-expanding stent and a stent advancing catheter, characterized in that;

the stent delivery sheath has a proximal end, a distal end and a lumen;

the self-expanding stent has an unexpanded state and an expanded state;

The stent advancing catheter has a catheter shaft with an expandable member mounted on the distal end of the catheter shaft;

The stent delivery sheath is provided with the stent advancing catheter, the stent advancing catheter is sleeved with a matching sliding sleeve block, and the sliding sleeve block is surrounded by a plurality of evenly distributed self-expanding stents, The self-expanding stent is sheathed with a matching gas permeable membrane, the self-expanding stent is connected with the sliding sleeve block through a movable assembly, and a guide catheter is provided on one side of the stent delivery sheath, and the guide catheter is There is a guide wire matched with it, and the guide wire is provided with an embolism protection component matched with it;

The embolic protection assembly comprises a tubular shaft provided with a catheter inlet matched with the guide wire; the guide wire sequentially passes through the guide catheter and the stenosis region in the carotid artery, the tubular shaft The upper sleeve is provided with an expanded breathable membrane, and an expanded stent filter is arranged in the expanded breathable membrane;

The stent advancing catheter is provided with a stent advancing sheath extending to the outside of the stent delivery sheath, the stent advancing sheath is connected with the sliding sleeve block, and one end of the stent advancing sheath extends to the outside of the stent advancing catheter There is a promotion department.

Preferably, the embolic protection assembly is sized and configured to be insertable through the lumen of the stent advancer sheath.

Preferably, the stent advancing sheath has an opening passing through the wall of the stent delivery sheath and communicating with the lumen at an intermediate position between the proximal end and the distal end of the stent delivery sheath.

Preferably, the opening is sized and configured to allow insertion of the tubular shaft of the embolic protection assembly therethrough.

Preferably, an automatic release sheath is provided on the stent delivery sheath, and the automatic release sheath surrounds the proximal end of the tubular shaft of the embolic protection assembly and the proximal end of the stent delivery sheath.

Preferably, a hemostatic valve is provided at the proximal end of the stent delivery sheath, the hemostatic valve being configured to provide a seal about the catheter shaft of the stent advancement catheter.

Preferably, the stent advances a shoulder at the distal end of the catheter sized and configured to urge the self-expanding stent through the lumen of the stent delivery sheath.

Preferably, a carrier balloon is provided on the surface of the expanded gas permeable membrane.

Preferably, a drug coating is provided on the surface of the carrier balloon, and the drug coating is in the shape of micron-scale fine needles.

The beneficial effects of the invention are as follows: in the treatment of carotid artery stenosis, the stent implantation can be protected from embolism through the integrated expanded stent filter, the operation is simple and convenient, and the expansion of the expanded breathable membrane on the expanded stent filter provides the carotid artery Completely reliable occlusion provides more effective fixation of the expanded gas permeable membrane within the stent, simplifying catheter manipulation in subsequent steps. The surface of the expandable gas permeable membrane is provided with a carrier balloon and a drug coating. When the drug coating reaches the injury site, the active drug is rapidly released from the surface of the balloon coating, and deposited on the surface of the blood vessel wall to achieve an effective drug concentration.

Description of drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the accompanying drawings required in the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some of the present invention. In the embodiments, for those of ordinary skill in the art, other drawings can also be obtained according to these drawings without any creative effort.

1 is a schematic structural diagram of an anti-embolism carotid angioplasty system according to an embodiment of the present invention;

2 is a schematic structural diagram of an embolism protection component in an anti-embolism carotid angioplasty system according to an embodiment of the present invention;

FIG. 3 is an enlarged structural schematic diagram of a cargo balloon in an anti-embolism carotid angioplasty system according to an embodiment of the present invention.

In the picture:

1. Stent delivery sheath; 2. Self-expanding stent; 3. Stent advancing catheter; 4. Proximal end; 5. Distal end; 11. Guide catheter; 12. Guide wire; 13. Embolic protection component; 14. Tubular shaft; 15. Catheter inlet; Section; 20. Self-release sheath, 21. Loading balloon, 22. Drug coating.

Detailed ways

In order to further illustrate the various embodiments, the present invention provides accompanying drawings, which are part of the disclosure of the present invention, and are mainly used to illustrate the embodiments, and can be used in conjunction with the relevant descriptions in the specification to explain the operation principles of the embodiments. For these, those of ordinary skill in the art will understand other possible implementations and the advantages of the present invention. Components in the figures are not drawn to scale, and similar component symbols are generally used to represent similar components.

According to an embodiment of the present invention, an anti-embolic carotid angioplasty system is provided.

Embodiment 1;

As shown in Figures 1-2, the anti-embolism carotid angioplasty system according to an embodiment of the present invention includes a stent delivery sheath 1, a self-expanding stent 2 and a stent advancing catheter 3, and is characterized in that:

The stent delivery sheath 1 has a proximal end 4, a distal end 5 and an inner cavity 6;

The self-expanding stent 2 has an unexpanded state and an expanded state;

The stent advancing catheter 3 should have a catheter shaft 7, and an expandable member is installed at the distal end of the catheter shaft 7;

The stent delivery sheath 1 is provided with the stent advancing catheter 3, the stent advancing catheter 3 is sleeved with a matching sliding sleeve block 8, and the sliding sleeve block 8 is surrounded with a number of uniformly distributed Described self-expanding stent 2, the self-expanding stent 2 is sleeved with a matching breathable membrane 9, the self-expanding stent 2 is connected with the sliding sleeve block 8 through the movable assembly 10, and the stent delivery sheath 1 A guide catheter 11 is provided on one side of the guide catheter, the guide catheter 11 is provided with a matching guide wire 12, and the guide wire 12 is provided with a matching embolism protection component 13;

The embolic protection assembly 13 includes a tubular shaft 14, and the tubular shaft 14 is provided with a catheter inlet 15 matched with the guide wire 12; the guide wire 12 passes through the guide catheter 11 and the carotid artery in sequence. In the narrow area 16, the tubular shaft 14 is sleeved with an expanding breathable membrane 17, and an expanding stent filter is arranged in the expanding breathable membrane 17;

The stent advancing catheter 3 is provided with a stent advancing sheath 18 extending to the outside of the stent delivery sheath 1, the stent advancing sheath 18 is connected with the sliding sleeve block 8, and one end of the stent advancing sheath 18 extends to A pushing portion 19 is provided outside the stent pushing catheter 3 .

Embodiment 2;

As shown in Figures 1-2, the embolic protection assembly 13 is sized and configured to be insertable through the lumen 6 of the stent advancer sheath 18, the stent advancer sheath 18 At an intermediate position between the proximal end 4 and the distal end 5 of the stent delivery sheath 1 , there is an opening through the wall of the stent delivery sheath and in communication with the lumen 6 .

Embodiment three;

As shown in Figures 1-2, the opening is sized and configured to allow insertion of the tubular shaft 14 of the embolic protection assembly 13 therethrough, and the stent delivery sheath 1 is provided with an automatic release sheath 20 , the automatic release sheath 20 surrounds the proximal end of the tubular shaft 14 of the embolic protection assembly 13 and the proximal end of the stent delivery sheath 1 together.

Embodiment four;

As shown in Figures 1-3, a hemostatic valve is provided at the proximal end 4 of the stent delivery sheath 1, the hemostatic valve is configured to provide a seal around the catheter shaft 7 of the stent advancement catheter 3, The shoulder at the distal end of the stent advancement catheter 3 is sized and configured to push the self-expanding stent 2 through the lumen 6 of the stent delivery sheath 1, so A drug coating 22 is provided on the surface of the cargo-carrying balloon 21 , and the drug coating 22 is in the shape of micron-scale fine needles. Specifically, the drug coating 22 includes pectin, an active drug, and the active drug is paclitaxel or docetaxel. Among them, the drug coating of the present invention uses pectin as an excipient, and is mixed with active drugs to form micron-sized microneedles. Through the intima of the blood vessel, the drug components are released to each membrane layer, and the affected part of the inner wall is gradually improved through the dual mechanism of osmotic superposition and slow-release transdermal. The surface of the coating is rapidly released, and the effective drug concentration is deposited on the surface of the blood vessel wall.

To sum up, with the aid of the above technical solutions of the present invention, in the treatment of carotid artery stenosis endothelioplasty stent implantation can form embolism protection through the integrated expansion stent filter, the operation is simple and convenient, and the expansion of the breathable membrane 17 can be used to expand the stent. Expansion of the screen provides complete and reliable occlusion of the carotid artery, provides more effective fixation of the expanded gas permeable membrane 17 within the stent, and simplifies catheter manipulation in subsequent steps.

The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the scope of the present invention. within the scope of protection.

Claims (9)

1. an anti-embolism carotid angioplasty system, comprising a stent delivery sheath (1), a self-expanding stent (2) and a stent advancing catheter (3), characterized in that; The stent delivery sheath (1) has a proximal end (4), a distal end (5) and an inner cavity (6); The self-expanding stent (2) has an unexpanded state and an expanded state; The stent advancing catheter (3) has a catheter shaft (7), and an expandable member is installed at the distal end of the catheter shaft (7); The stent delivery sheath (1) is provided with the stent advancing catheter (3), and the stent advancing catheter (3) is sleeved with a matching sliding sleeve block (8), the sliding sleeve block (8) ) is surrounded with a plurality of uniformly distributed self-expanding supports (2), the self-expanding support (2) is sleeved with a matching gas permeable membrane (9), and the self-expanding support (2) moves through the The assembly (10) is connected with the sliding sleeve block (8), a guide catheter (11) is provided on one side of the stent delivery sheath (1), and a guide catheter (11) is provided with a guide catheter (11) matching the guide catheter. a wire (12), the guide wire (12) is provided with a matching embolic protection component (13); The embolic protection assembly (13) comprises a tubular shaft (14), and the tubular shaft (14) is provided with a catheter inlet (15) matching the guide wire (12); the guide wire (12) is arranged in sequence Passing through the guide catheter (11) and the stenosis region (16) in the carotid artery, the tubular shaft (14) is sheathed with an expansion gas permeable membrane (17), and the expansion gas permeable membrane (17) is provided with an expansion gas membrane (17). Bracket filter; The stent pushing catheter (3) is provided with a stent pushing sheath (18) extending outside the stent delivery sheath (1), and the stent pushing sheath (18) is connected with the sliding sleeve block (8), One end of the stent pushing sheath (18) extends to the outside of the stent pushing catheter (3), and a pushing portion (19) is provided. 2. An anti-embolic carotid angioplasty system according to claim 1, wherein the embolic protection component (13) is dimensioned and configured to be insertable The lumen (6) of the sheath (18) is advanced through the stent. 3. An anti-embolism carotid angioplasty system according to claim 1, wherein the stent advancing sheath (18) is located between the proximal end (4) of the stent delivery sheath (1) and the An opening passing through the wall of the stent delivery sheath and communicating with the lumen (6) is provided at an intermediate position between the distal ends (5). 4. An anti-embolic carotid angioplasty system according to claim 3, wherein said opening is sized and configured to allow said tubular shaft (14) of said embolic protection assembly (13) ) inserted through. 5. An anti-embolism carotid angioplasty system according to claim 1, wherein an automatic release sheath (20) is provided on the stent delivery sheath (1), and the automatic release sheath (20) The proximal end of the tubular shaft (14) of the embolic protection assembly (13) and the proximal end of the stent delivery sheath (1) are enclosed together. 6. The anti-embolism carotid angioplasty system according to claim 1, wherein a hemostatic valve is provided at the proximal end (4) of the stent delivery sheath (1), and the hemostatic valve is The catheter shaft (7) is configured to provide a seal around the stent advancement catheter (3). 7. A kind of anti-embolism carotid angioplasty system according to claim 1, is characterized in that, the shoulder at the distal end of described stent advancement catheter (3), sets the size of described shoulder and makes it structure to push the self-expanding stent (2) through the lumen (6) of the stent delivery sheath (1). 8 . The anti-embolism carotid arterioplasty system according to claim 1 , wherein a carrier balloon ( 21 ) is provided on the surface of the expanding gas permeable membrane ( 17 ). 9 . 9. The anti-embolism carotid angioplasty system according to claim 8, wherein a drug coating (22) is provided on the surface of the carrier balloon (21), and the drug coating (22) is Micron-sized tiny needles.

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